Etoposide Metabolites Enhance DNA Topoisomerase II Cleavage near Leukemia-Associated MLL Translocation Breakpoints
Lovett, Brian D, Strumberg, Dirk, Blair, Ian A, Pang, Shaokun, Burden, Donald A, Megonigal, Maureen D, Rappaport, Eric F, Rebbeck, Timothy R, Osheroff, Neil, Pommier, Yves G, Felix, Carolyn A
Published in Biochemistry (Easton) (06.02.2001)
Published in Biochemistry (Easton) (06.02.2001)
Get full text
Journal Article
Association of Germline p53 Mutation With MLL Segmental Jumping Translocation in Treatment-Related Leukemia
Felix, Carolyn A., Megonigal, Maureen D., Chervinsky, David S., Leonard, Debra G.B., Tsuchida, Nao, Kakati, Surabhi, Block, Anne Marie W., Fisher, John, Grossi, Mauro, Salhany, Kevin I., Jani-Sait, Sheila N., Aplan, Peter D.
Published in Blood (15.06.1998)
Published in Blood (15.06.1998)
Get full text
Journal Article
Potential role for wild-type p53 in leukemias with MLL gene translocations
MEGONIGAL, M. D, RAPPAPORT, E. F, NOWELL, P. C, LANGE, B. J, FELIX, C. A
Published in Oncogene (12.03.1998)
Published in Oncogene (12.03.1998)
Get full text
Journal Article
t(11;22)(q23;q11.2) in Acute Myeloid Leukemia of Infant Twins Fuses MLL with hCDCrel, a Cell Division Cycle Gene in the Genomic Region of Deletion in DiGeorge and Velocardiofacial Syndromes
Megonigal, Maureen D., Rappaport, Eric F., Jones, Douglas H., Williams, Terence M., Lovett, Brian D., Kelly, Kara M., Lerou, Paul H., Moulton, Thomas, Budarf, Marcia L., Felix, Carolyn A.
Published in Proceedings of the National Academy of Sciences - PNAS (26.05.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (26.05.1998)
Get full text
Journal Article
Near-Precise Interchromosomal Recombination and Functional DNA Topoisomerase II Cleavage Sites at MLL and AF-4 Genomic Breakpoints in Treatment-Related Acute Lymphoblastic Leukemia with t(4; 11) Translocation
Lovett, Brian D., Lo Nigro, Luca, Rappaport, Eric F., Blair, Ian A., Osheroff, Neil, Zheng, Naiyu, Megonigal, Maureen D., Williams, Wendy Reed, Nowell, Peter C., Felix, Carolyn A.
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2001)
Get full text
Journal Article
Detection of Leukemia-Associated MLL-GAS7 Translocation Early during Chemotherapy with DNA Topoisomerase II Inhibitors
Megonigal, M D, Cheung, N K, Rappaport, E F, Nowell, P C, Wilson, R B, Jones, D H, Addya, K, Leonard, D G, Kushner, B H, Williams, T M, Lange, B J, Felix, C A
Published in Proceedings of the National Academy of Sciences - PNAS (14.03.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (14.03.2000)
Get full text
Journal Article
Panhandle PCR for cDNA: A Rapid Method for Isolation of MLL Fusion Transcripts Involving Unknown Partner Genes
Megonigal, Maureen D., Rappaport, Eric F., Wilson, Robert B., Jones, Douglas H., Whitlock, James A., Ortega, Jorge A., Slater, Diana J., Nowell, Peter C., Felix, Carolyn A.
Published in Proceedings of the National Academy of Sciences - PNAS (15.08.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (15.08.2000)
Get full text
Journal Article
Panhandle PCR Strategy to Amplify MLL Genomic Breakpoints in Treatment-Related Leukemias
Megonigal, Maureen D., Rappaport, Eric F., Jones, Douglas H., Kim, Caroline S., Nowell, Peter C., Lange, Beverly J., Felix, Carolyn A.
Published in Proceedings of the National Academy of Sciences - PNAS (14.10.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (14.10.1997)
Get full text
Journal Article
t(3;11) translocation in treatment-related acute myeloid leukemia fuses MLL with the GMPS (GUANOSINE 5′ MONOPHOSPHATE SYNTHETASE) gene
Pegram, Linda D., Megonigal, Maureen D., Lange, Beverly J., Nowell, Peter C., Rowley, Janet D., Rappaport, Eric F., Felix, Carolyn A.
Published in Blood (15.12.2000)
Published in Blood (15.12.2000)
Get full text
Journal Article
Panhandle Polymerase Chain Reaction Amplifies MLL Genomic Translocation Breakpoint Involving Unknown Partner Gene
Felix, Carolyn A., Kim, Caroline S., Megonigal, Maureen D., Slater, Diana J., Jones, Douglas H., Spinner, Nancy B., Stump, Tammy, Hosler, Matthew R., Nowell, Peter C., Lange, Beverly J., Rappaport, Eric F.
Published in Blood (15.12.1997)
Published in Blood (15.12.1997)
Get full text
Journal Article
Duplicated regions of AF-4 intron 4 at t(4;11) translocation breakpoints
Felix, C A, Hosler, M R, Slater, D J, Megonigal, M D, Lovett, B D, Williams, T M, Nowell, P C, Spinner, N B, Owens, N L, Hoxie, J, Croce, C M, Lange, B J, Rappaport, E F
Published in Molecular diagnosis (01.12.1999)
Published in Molecular diagnosis (01.12.1999)
Get more information
Journal Article
Reciprocal DNA topoisomerase II cleavage events at 5'-TATTA-3' sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further processing
WHITMARSH, Ryan J, SAGINARIO, Charles, SLATER, Diana J, RIED, Thomas, KNUTSEN, Turid, BLAIR, Ian A, FELIX, Carolyn A, YA ZHUO, HILGENFELD, Eva, RAPPAPORT, Eric F, MEGONIGAL, Maureen D, CARROLL, Martin, MINGLI LIU, OSHEROFF, Neil, CHEUNG, Nai-Kong V
Published in Oncogene (20.11.2003)
Published in Oncogene (20.11.2003)
Get full text
Journal Article
Panhandle Polymerase Chain Reaction Amplifies MLL Genomic Translocation Breakpoint Involving Unknown Partner Gene
Felix, Carolyn A., Kim, Caroline S., Megonigal, Maureen D., Slater, Diana J., Jones, Douglas H., Spinner, Nancy B., Stump, Tammy, Hosler, Matthew R., Nowell, Peter C., Lange, Beverly J., Rappaport, Eric F.
Published in Blood (15.12.1997)
Published in Blood (15.12.1997)
Get full text
Journal Article