Mode of action human relevance (species concordance) framework: Evolution of the Bradford Hill considerations and comparative analysis of weight of evidence
Meek, M. E. (Bette), Palermo, Christine M., Bachman, Ammie N., North, Colin M., Jeffrey Lewis, R.
Published in Journal of applied toxicology (01.06.2014)
Published in Journal of applied toxicology (01.06.2014)
Get full text
Journal Article
IPCS Framework for Analyzing the Relevance of a Noncancer Mode of Action for Humans
Boobis, Alan R., Doe, John E., Heinrich-Hirsch, Barbara, (Bette) Meek, M. E., Munn, Sharon, Ruchirawat, Mathuros, Schlatter, Josef, Seed, Jennifer, Vickers, Carolyn
Published in Critical reviews in toxicology (01.01.2008)
Published in Critical reviews in toxicology (01.01.2008)
Get full text
Journal Article
New developments in the evolution and application of the WHO/IPCS framework on mode of action/species concordance analysis
Meek, M. E., Boobis, A., Cote, I., Dellarco, V., Fotakis, G., Munn, S., Seed, J., Vickers, C.
Published in Journal of applied toxicology (01.01.2014)
Published in Journal of applied toxicology (01.01.2014)
Get full text
Journal Article
How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology
Wittwehr, Clemens, Aladjov, Hristo, Ankley, Gerald, Byrne, Hugh J, de Knecht, Joop, Heinzle, Elmar, Klambauer, Günter, Landesmann, Brigitte, Luijten, Mirjam, MacKay, Cameron, Maxwell, Gavin, Meek, M E Bette, Paini, Alicia, Perkins, Edward, Sobanski, Tomasz, Villeneuve, Dan, Waters, Katrina M, Whelan, Maurice
Published in Toxicological sciences (01.02.2017)
Published in Toxicological sciences (01.02.2017)
Get full text
Journal Article
IPCS Framework for Analyzing the Relevance of a Cancer Mode of Action for Humans
Boobis, Alan R., Cohen, Samuel M., Dellarco, Vicki, McGregor, Douglas, Meek, M. E. (Bette), Vickers, Carolyn, Willcocks, Deborah, Farland, William
Published in Critical reviews in toxicology (01.11.2006)
Published in Critical reviews in toxicology (01.11.2006)
Get full text
Journal Article
Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity
Bal-Price, Anna, Lein, Pamela J., Keil, Kimberly P., Sethi, Sunjay, Shafer, Timothy, Barenys, Marta, Fritsche, Ellen, Sachana, Magdalini, Meek, M.E. (Bette)
Published in Neurotoxicology (Park Forest South) (01.03.2017)
Published in Neurotoxicology (Park Forest South) (01.03.2017)
Get full text
Journal Article
Evolution of chemical-specific adjustment factors (CSAF) based on recent international experience; increasing utility and facilitating regulatory acceptance
Bhat, Virunya S., Meek, M.E. (Bette), Valcke, Mathieu, English, Caroline, Boobis, Alan, Brown, Richard
Published in Critical reviews in toxicology (21.10.2017)
Published in Critical reviews in toxicology (21.10.2017)
Get full text
Journal Article
A Framework for Human Relevance Analysis of Information on Carcinogenic Modes of Action
Meek, M. E. (Bette), Bucher, John R., Cohen, Samuel M., Dellarco, Vicki, Hill, Richard N., Lehman-McKeeman, Lois D., Longfellow, David G., Pastoor, Timothy, Seed, Jennifer, Patton, Dorothy E.
Published in Critical reviews in toxicology (01.01.2003)
Published in Critical reviews in toxicology (01.01.2003)
Get full text
Journal Article
Development of the adverse outcome pathway "alkylation of DNA in male premeiotic germ cells leading to heritable mutations" using the OECD's users' handbook supplement
Yauk, Carole L., Lambert, Iain B., Meek, M.E. (Bette), Douglas, George R., Marchetti, Francesco
Published in Environmental and molecular mutagenesis (01.12.2015)
Published in Environmental and molecular mutagenesis (01.12.2015)
Get full text
Journal Article
4-Aminobiphenyl and DNA Reactivity: Case Study Within the Context of the 2006 IPCS Human Relevance Framework for Analysis of a Cancer Mode of Action for Humans
Cohen, Samuel M., Boobis, Alan R., (Bette) Meek, M. E., Preston, R. Julian, McGregor, Douglas B.
Published in Critical reviews in toxicology (01.11.2006)
Published in Critical reviews in toxicology (01.11.2006)
Get full text
Journal Article
Framework for human health risk assessment of non-cancer effects resulting from short-duration and intermittent exposures to chemicals
Haber, Lynne T., Sandhu, Reena, Li-Muller, Angela, Mohapatra, Asish, Petrovic, Sanya, Meek, M. E. (Bette)
Published in Journal of applied toxicology (01.09.2016)
Published in Journal of applied toxicology (01.09.2016)
Get full text
Journal Article
Using mode of action information to improve regulatory decision-making: An ECETOC/ILSI RF/HESI workshop overview
Carmichael, Neil, Bausen, Melanie, Boobis, Alan R., Cohen, Samuel M., Embry, Michelle, Fruijtier-Pölloth, Claudia, Greim, Helmut, Lewis, Richard, (Bette) Meek, M.E., Mellor, Howard, Vickers, Carolyn, Doe, John
Published in Critical reviews in toxicology (01.03.2011)
Published in Critical reviews in toxicology (01.03.2011)
Get full text
Journal Article
Application of benchmark dose modeling to protein expression data in the development and analysis of mode of action/adverse outcome pathways for testicular toxicity
Chepelev, Nikolai L., Meek, M. E. (Bette), Yauk, Carole Lyn
Published in Journal of applied toxicology (01.11.2014)
Published in Journal of applied toxicology (01.11.2014)
Get full text
Journal Article
Overview: Using Mode of Action and Life Stage Information to Evaluate the Human Relevance of Animal Toxicity Data
Seed, Jennifer, Carney, Edward W., Corley, Richard A., Crofton, Kevin M., DeSesso, John M., Foster, Paul M. D., Kavlock, Robert, Kimmel, Gary, Klaunig, James, Meek, M. E., Preston, R. Julian, Slikker, William, Tabacova, Sonia, Williams, Gary M., Wiltse, Jeanette, Zoeller, R. Thomas, Fenner-Crisp, Penelope, Patton, Dorothy E.
Published in Critical reviews in toxicology (01.10.2005)
Published in Critical reviews in toxicology (01.10.2005)
Get full text
Journal Article
Case study illustrating the WHO IPCS guidance on characterization and application of physiologically based pharmacokinetic models in risk assessment
Meek, M.E. (Bette), Barton, Hugh A., Bessems, Jos G., Lipscomb, John C., Krishnan, Kannan
Published in Regulatory toxicology and pharmacology (01.06.2013)
Published in Regulatory toxicology and pharmacology (01.06.2013)
Get full text
Journal Article