Acid ceramidase deficiency: Farber disease and SMA-PME
Yu, Fabian P S, Amintas, Samuel, Levade, Thierry, Medin, Jeffrey A
Published in Orphanet journal of rare diseases (20.07.2018)
Published in Orphanet journal of rare diseases (20.07.2018)
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Lentivirus-mediated gene therapy for Fabry disease
Khan, Aneal, Barber, Dwayne L., Huang, Ju, Rupar, C. Anthony, Rip, Jack W., Auray-Blais, Christiane, Boutin, Michel, O’Hoski, Pamela, Gargulak, Kristy, McKillop, William M., Fraser, Graeme, Wasim, Syed, LeMoine, Kaye, Jelinski, Shelly, Chaudhry, Ahsan, Prokopishyn, Nicole, Morel, Chantal F., Couban, Stephen, Duggan, Peter R., Fowler, Daniel H., Keating, Armand, West, Michael L., Foley, Ronan, Medin, Jeffrey A.
Published in Nature communications (25.02.2021)
Published in Nature communications (25.02.2021)
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Genetic ablation of acid ceramidase in Krabbe disease confirms the psychosine hypothesis and identifies a new therapeutic target
Li, Yedda, Xu, Yue, Benitez, Bruno A., Nagree, Murtaza S., Dearborn, Joshua T., Jiang, Xuntian, Guzman, Miguel A., Woloszynek, Josh C., Giaramita, Alex, Yip, Bryan K., Elsbernd, Joseph, Babcock, Michael C., Lo, Melanie, Fowler, Stephen C., Wozniak, David F., Vogler, Carole A., Medin, Jeffrey A., Crawford, Brett E., Sands, Mark S.
Published in Proceedings of the National Academy of Sciences - PNAS (01.10.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (01.10.2019)
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On-Tissue Localization of Ceramides and Other Sphingolipids by MALDI Mass Spectrometry Imaging
Jones, E. Ellen, Dworski, Shaalee, Canals, Daniel, Casas, Josefina, Fabrias, Gemma, Schoenling, Drew, Levade, Thierry, Denlinger, Chadrick, Hannun, Yusuf A, Medin, Jeffrey A, Drake, Richard R
Published in Analytical chemistry (Washington) (19.08.2014)
Published in Analytical chemistry (Washington) (19.08.2014)
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Sarcoma IL-12 overexpression facilitates NK cell immunomodulation
Rademacher, Mary Jo, Cruz, Anahi, Faber, Mary, Oldham, Robyn A. A., Wang, Dandan, Medin, Jeffrey A., Schloemer, Nathan J.
Published in Scientific reports (15.04.2021)
Published in Scientific reports (15.04.2021)
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Ceramide metabolism alterations contribute to Tumor Necrosis Factor-induced melanoma dedifferentiation and predict resistance to immune checkpoint inhibitors in advanced melanoma patients
Dufau, Carine, Genais, Matthieu, Mucher, Elodie, Jung, Benjamin, Garcia, Virginie, Montfort, Anne, Tosolini, Marie, Clarke, Christopher J, Medin, Jeffrey A, Levade, Thierry, Delord, Jean-Pierre, Meyer, Nicolas, Pancaldi, Vera, Andrieu-Abadie, Nathalie, Ségui, Bruno
Published in Frontiers in immunology (29.07.2024)
Published in Frontiers in immunology (29.07.2024)
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Acid Ceramidase Deficiency: Bridging Gaps between Clinical Presentation, Mouse Models, and Future Therapeutic Interventions
Kleynerman, Annie, Rybova, Jitka, Faber, Mary L, McKillop, William M, Levade, Thierry, Medin, Jeffrey A
Published in Biomolecules (Basel, Switzerland) (01.02.2023)
Published in Biomolecules (Basel, Switzerland) (01.02.2023)
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Novel anti-CD30/CD3 bispecific antibodies activate human T cells and mediate potent anti-tumor activity
Faber, Mary L, Oldham, Robyn A A, Thakur, Archana, Rademacher, Mary Jo, Kubicka, Ewa, Dlugi, Theresa A, Gifford, Steven A, McKillop, William M, Schloemer, Nathan J, Lum, Lawrence G, Medin, Jeffrey A
Published in Frontiers in immunology (14.08.2023)
Published in Frontiers in immunology (14.08.2023)
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Neuraminidase 1 activates insulin receptor and reverses insulin resistance in obese mice
Fougerat, Anne, Pan, Xuefang, Smutova, Victoria, Heveker, Nikolaus, Cairo, Christopher W., Issad, Tarik, Larrivée, Bruno, Medin, Jeffrey A., Pshezhetsky, Alexey V.
Published in Molecular metabolism (Germany) (01.06.2018)
Published in Molecular metabolism (Germany) (01.06.2018)
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Autologous, lentivirus‐modified, T‐rapa cell “micropharmacies” for lysosomal storage disorders
Nagree, Murtaza S, Felizardo, Tania C, Faber, Mary L, Rybova, Jitka, Rupar, C Anthony, Foley, S Ronan, Fuller, Maria, Fowler, Daniel H, Medin, Jeffrey A
Published in EMBO molecular medicine (07.04.2022)
Published in EMBO molecular medicine (07.04.2022)
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Systemic ceramide accumulation leads to severe and varied pathological consequences
Alayoubi, Abdulfatah M., Wang, James C. M., Au, Bryan C. Y., Carpentier, Stéphane, Garcia, Virginie, Dworski, Shaalee, El‐Ghamrasni, Samah, Kirouac, Kevin N., Exertier, Mathilde J., Xiong, Zi Jian, Privé, Gilbert G., Simonaro, Calogera M., Casas, Josefina, Fabrias, Gemma, Schuchman, Edward H., Turner, Patricia V., Hakem, Razqallah, Levade, Thierry, Medin, Jeffrey A.
Published in EMBO molecular medicine (01.06.2013)
Published in EMBO molecular medicine (01.06.2013)
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Development of Novel Immunotherapies for Multiple Myeloma
Al-Hujaily, Ensaf M, Oldham, Robyn A A, Hari, Parameswaran, Medin, Jeffrey A
Published in International journal of molecular sciences (08.09.2016)
Published in International journal of molecular sciences (08.09.2016)
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Adiponectin overexpression improves metabolic abnormalities caused by acid ceramidase deficiency but does not prolong lifespan in a mouse model of Farber Disease
Norris, Marie K., Tippetts, Trevor S., Wilkerson, Joseph L., Nicholson, Rebekah J., Maschek, J. Alan, Levade, Thierry, Medin, Jeffrey A., Summers, Scott A., Holland, William L.
Published in Molecular genetics and metabolism reports (01.06.2024)
Published in Molecular genetics and metabolism reports (01.06.2024)
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Natural killer cell lines preferentially kill clonogenic multiple myeloma cells and decrease myeloma engraftment in a bioluminescent xenograft mouse model
SWIFT, Brenna E, WILLIAMS, Brent A, KOSAKA, Yoko, WANG, Xing-Hua, MEDIN, Jeffrey A, VISWANATHAN, Sowmya, MARTINEZ-LOPEZ, Joaquin, KEATING, Armand
Published in Haematologica (Roma) (01.07.2012)
Published in Haematologica (Roma) (01.07.2012)
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Yin and Yang of mesenchymal stem cells and aplastic anemia
Broglie, Larisa, Margolis, David, Medin, Jeffrey A
Published in World journal of stem cells (26.12.2017)
Published in World journal of stem cells (26.12.2017)
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Persistent hematopoietic polyclonality after lentivirus-mediated gene therapy for Fabry disease
Saleh, Amr H., Rothe, Michael, Barber, Dwayne L., McKillop, William M., Fraser, Graeme, Morel, Chantal F., Schambach, Axel, Auray-Blais, Christiane, West, Michael L., Khan, Aneal, Fowler, Daniel H., Rupar, C. Anthony, Foley, Ronan, Medin, Jeffrey A., Keating, Armand
Published in Molecular therapy. Methods & clinical development (09.03.2023)
Published in Molecular therapy. Methods & clinical development (09.03.2023)
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Spinal muscular atrophy-like phenotype in a mouse model of acid ceramidase deficiency
Nagree, Murtaza S., Rybova, Jitka, Kleynerman, Annie, Ahrenhoerster, Carissa J., Saville, Jennifer T., Xu, TianMeng, Bachochin, Maxwell, McKillop, William M., Lawlor, Michael W., Pshezhetsky, Alexey V., Isaeva, Olena, Budde, Matthew D., Fuller, Maria, Medin, Jeffrey A.
Published in Communications biology (25.05.2023)
Published in Communications biology (25.05.2023)
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Evaluation of Bystander Cell Killing Effects in Suicide Gene Therapy of Cancer: Engineered Thymidylate Kinase (TMPK)/AZT Enzyme-Prodrug Axis
Sato, Takeya, Neschadim, Anton, Nakagawa, Ryo, Yanagisawa, Teruyuki, Medin, Jeffrey A
Published in Methods in molecular biology (Clifton, N.J.) (2015)
Published in Methods in molecular biology (Clifton, N.J.) (2015)
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