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An Enterohepatic Recirculation Population Pharmacokinetic and MIC-1 Pharmacokinetic-Pharmacodynamic Model for the MDM2 Inhibitor Navtemadlin (KRT-232) in Healthy Subjects
Zhang, Lu, Poland, Bill, Green, Michelle, Wong, Shekman, Slatter, J. Greg
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation
Ho, Jenny N.H.G., Schmidt, Dominik, Lowinus, Theresa, Ryoo, Jeongmin, Dopfer, Elaine-Pashupati, Gonzalo Núñez, Nicolás, Costa-Pereira, Sara, Toffalori, Cristina, Punta, Marco, Fetsch, Viktor, Wertheimer, Tobias, Rittmann, Marie-Claire, Braun, Lukas M., Follo, Marie, Briere, Christelle, Vinnakota, Janaki Manoja, Langenbach, Marlene, Koppers, Felicitas, Shoumariyeh, Khalid, Engel, Helena, Rückert, Tamina, Märklin, Melanie, Holzmayer, Samuel, Illert, Anna L., Magon, Federica, Andrieux, Geoffroy, Duquesne, Sandra, Pfeifer, Dietmar, Staniek, Julian, Rizzi, Marta, Miething, Cornelius, Köhler, Natalie, Duyster, Justus, Menssen, Hans D., Boerries, Melanie, Buescher, Joerg M., Cabezas-Wallscheid, Nina, Blazar, Bruce R., Apostolova, Petya, Vago, Luca, Pearce, Erika L., Becher, Burkhard, Zeiser, Robert
Published in Blood (08.09.2022)
Published in Blood (08.09.2022)
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KLF5/MDM2 Axis Modulates Oxidative Stress and Epithelial-Mesenchymal Transition in Human Lens Epithelial Cells: The Role in Diabetic Cataract
Li, Xiao, Chen, Doudou, Ouyang, Bowen, Wang, Shengnan, Li, Yawei, Li, Li, Zhu, Siquan, Zheng, Guangying
Published in Laboratory investigation (01.11.2023)
Published in Laboratory investigation (01.11.2023)
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miR-661 downregulates both Mdm2 and Mdm4 to activate p53
Hoffman, Y, Bublik, D R, Pilpel, Y, Oren, M
Published in Cell death and differentiation (01.02.2014)
Published in Cell death and differentiation (01.02.2014)
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Concentration-QTc (C-QTc) Analysis of the MDM2 Inhibitor KRT-232 (formerly AMG 232) in Subjects with Advanced Solid Tumors, Multiple Myeloma, or Acute Myeloid Leukemia
Taylor, Adekemi, Allard, Martine, Kresja, Cecile, Lee, Dana, Slatter, Greg
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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The C-terminal SAM domain of p73 binds to the N terminus of MDM2
Neira, José L., Díaz-García, Clara, Prieto, Manuel, Coutinho, Ana
Published in Biochimica et biophysica acta. General subjects (01.04.2019)
Published in Biochimica et biophysica acta. General subjects (01.04.2019)
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Primary Cardiac Intimal Sarcoma: Multi-Layered Strategy and Core Role of MDM2 Amplification/Co-Amplification and MDM2 Immunostaining
Nistor, Claudiu, Stanciu Gavan, Camelia, Birceanu, Adelina, Betianu, Cezar, Carsote, Mara, Cucu, Anca-Pati, Stanciu, Mihaela, Popa, Florina, Ciuche, Adrian, Ciobica, Mihai-Lucian
Published in Diagnostics (Basel) (28.04.2024)
Published in Diagnostics (Basel) (28.04.2024)
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CHOP regulates the p53–MDM2 axis and is required for neuronal survival after seizures
Engel, Tobias, Sanz-Rodgriguez, Amaya, Jimenez-Mateos, Eva M., Concannon, Caoimhin G., Jimenez-Pacheco, Alba, Moran, Catherine, Mesuret, Guillaume, Petit, Emilie, Delanty, Norman, Farrell, Michael A., O’Brien, Donncha F., Prehn, Jochen H. M., Lucas, Jose J., Henshall, David C.
Published in Brain (London, England : 1878) (01.02.2013)
Published in Brain (London, England : 1878) (01.02.2013)
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Therapy-relevant MDM2 amplification in cholangiocarcinomas in Caucasian patients
Lyu, Su Ir, Plum, Patrick Sven, Fretter, Caroline, Simon, Adrian Georg, Bedau, Tillmann, Knipper, Karl, Thomas, Michael N., Stippel, Dirk, Wagner, Britta Janina, Bruns, Christiane, Waldschmidt, Dirk, Büttner, Reinhard, Drebber, Uta, Quaas, Alexander
Published in Therapeutic advances in medical oncology (01.01.2024)
Published in Therapeutic advances in medical oncology (01.01.2024)
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MDM2 Copy Numbers in Well-Differentiated and Dedifferentiated Liposarcoma
Ware, Patrick L., Snow, Anthony N., Gvalani, Maya, Pettenati, Mark J., Qasem, Shadi A.
Published in American journal of clinical pathology (01.03.2014)
Published in American journal of clinical pathology (01.03.2014)
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MDM2 promoter del1518 polymorphism and cancer risk: evidence from 22,931 subjects
Hua, Wenfeng, Zhang, Anqi, Duan, Ping, Zhu, Jinhong, Zhao, Yuan, He, Jing, Zhang, Zhi
Published in OncoTargets and therapy (01.01.2017)
Published in OncoTargets and therapy (01.01.2017)
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MDM2 SNP309 variation contributes to leukemia risk: meta-analyses based on 7259 subjects
Zhuo, Wenlei, Zhang, Liang, Ling, Junjun, Zhu, Bo, Chen, Zhengtang
Published in Leukemia & lymphoma (01.11.2012)
Published in Leukemia & lymphoma (01.11.2012)
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Association of Interactions between Metabolic 'Caretaker' Genes, p53, MDM2, and Tobacco Use with the Risk of Oral Cancer: A Multifactor Dimensionality Reduction Approach
Singh, Ragini D, Patel, Kinjal A, Patel, Jayendra B, Patel, Prabhudas S
Published in Asian Pacific journal of cancer prevention : APJCP (01.04.2023)
Published in Asian Pacific journal of cancer prevention : APJCP (01.04.2023)
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Association of Insertion/Deletion Polymorphisms of MDM2, MCP-1 and VEGF with Esophageal Cancer Risk in North-West Indians: A Case - Control Study
Mahajan, Deepanshi, Sambyal, Vasudha, Uppal, Manjit Singh, Sudan, Meena, Guleria, Kamlesh
Published in Asian Pacific journal of cancer prevention : APJCP (01.05.2025)
Published in Asian Pacific journal of cancer prevention : APJCP (01.05.2025)
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The T309G MDM2 Gene Polymorphism Is a Novel Risk Factor for Proliferative Vitreoretinopathy
Pastor-Idoate, Salvador, Rodríguez-Hernández, Irene, Rojas, Jimena, Fernández, Itziar, García-Gutiérrez, María T., Ruiz-Moreno, José M., Rocha-Sousa, Amandio, Ramkissoon, Yashin, Harsum, Steven, MacLaren, Robert E., Charteris, David, VanMeurs, Jan C., González-Sarmiento, Rogelio, Pastor, José C.
Published in PloS one (09.12.2013)
Published in PloS one (09.12.2013)
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MDM2 SNP309T>G polymorphism increases susceptibility to hepatitis B virus-related hepatocellular carcinoma in a northeast Han Chinese population
Wang, Xi, Zhang, Xuelong, Qiu, Bing, Tang, Yinhua, Sun, He, Ji, Hongfei, Liu, Yan, Shi, Lijun, Song, Guang, Yang, Youlin
Published in Liver international (01.08.2012)
Published in Liver international (01.08.2012)
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