Search Results - "MCPHEAT, Jane" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Discovery of retinoic acid receptor agonists as proliferators of cardiac progenitor cells through a phenotypic screening approach

Discovery of retinoic acid receptor agonists as proliferators of cardiac progenitor cells through a phenotypic screening approach

by Drowley, Lauren, McPheat, Jane, Nordqvist, Anneli, Peel, Samantha, Karlsson, Ulla, Martinsson, Sofia, Müllers, Erik, Dellsén, Anita, Knight, Sinead, Barrett, Ian, Sánchez, José, Magnusson, Björn, Greber, Boris, Wang, Qing‐Dong, Plowright, Alleyn T.
Published in Stem cells translational medicine (01.01.2020)

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AZD0284, a Potent, Selective, and Orally Bioavailable Inverse Agonist of Retinoic Acid Receptor-Related Orphan Receptor C2

AZD0284, a Potent, Selective, and Orally Bioavailable Inverse Agonist of Retinoic Acid Receptor-Related Orphan Receptor C2

by Narjes, Frank, Llinas, Antonio, von Berg, Stefan, Jirholt, Johan, Lever, Sarah, Pehrson, Rikard, Collins, Mia, Malmberg, Anna, Svanberg, Petter, Xue, Yafeng, Olsson, Roine I, Malmberg, Jesper, Hughes, Glyn, Hossain, Nafizal, Grindebacke, Hanna, Leffler, Agnes, Krutrök, Nina, Bäck, Elisabeth, Ramnegård, Marie, Lepistö, Matti, Thunberg, Linda, Aagaard, Anna, McPheat, Jane, Hansson, Eva L, Chen, Rongfeng, Xiong, Yao, Hansson, Thomas G
Published in Journal of medicinal chemistry (23.09.2021)

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Potent and Orally Bioavailable Inverse Agonists of RORγt Resulting from Structure-Based Design

Potent and Orally Bioavailable Inverse Agonists of RORγt Resulting from Structure-Based Design

by Narjes, Frank, Xue, Yafeng, von Berg, Stefan, Malmberg, Jesper, Llinas, Antonio, Olsson, Roine I, Jirholt, Johan, Grindebacke, Hanna, Leffler, Agnes, Hossain, Nafizal, Lepistö, Matti, Thunberg, Linda, Leek, Hanna, Aagaard, Anna, McPheat, Jane, Hansson, Eva L, Bäck, Elisabeth, Tångefjord, Stefan, Chen, Rongfeng, Xiong, Yao, Hongbin, Ge, Hansson, Thomas G
Published in Journal of medicinal chemistry (13.09.2018)

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Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (T(H)17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR gamma

Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (T(H)17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR gamma

by Olsson, Roine I., Xue, Yafeng, von Berg, Stefan, Aagaard, Anna, McPheat, Jane, Hansson, Eva L., Bernstrom, Jenny, Hansson, Pia, Jirholt, Johan, Grindebacke, Hanna, Leffler, Agnes, Chen, Rongfeng, Xiong, Yao, Ge, Hongbin, Hansson, Thomas G., Narjes, Frank
Published in ChemMedChem (19.01.2016)

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Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor RORγ

Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor RORγ

by Olsson, Roine I., Xue, Yafeng, von Berg, Stefan, Aagaard, Anna, McPheat, Jane, Hansson, Eva L., Bernström, Jenny, Hansson, Pia, Jirholt, Johan, Grindebacke, Hanna, Leffler, Agnes, Chen, Rongfeng, Xiong, Yao, Ge, Hongbin, Hansson, Thomas G., Narjes, Frank
Published in ChemMedChem (19.01.2016)

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Characterization of a Small Molecule Inhibitor of Plasminogen Activator Inhibitor Type 1 That Accelerates the Transition into the Latent Conformation

Characterization of a Small Molecule Inhibitor of Plasminogen Activator Inhibitor Type 1 That Accelerates the Transition into the Latent Conformation

by Fjellström, Ola, Deinum, Johanna, Sjögren, Tove, Johansson, Carina, Geschwindner, Stefan, Nerme, Viveca, Legnehed, Anne, McPheat, Jane, Olsson, Karolina, Bodin, Cristian, Paunovic, Amalia, Gustafsson, David
Published in The Journal of biological chemistry (11.01.2013)

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Discovery of Potent and Orally Bioavailable Inverse Agonists of the Retinoic Acid Receptor-Related Orphan Receptor C2

Discovery of Potent and Orally Bioavailable Inverse Agonists of the Retinoic Acid Receptor-Related Orphan Receptor C2

by von Berg, Stefan, Xue, Yafeng, Collins, Mia, Llinas, Antonio, Olsson, Roine I, Halvarsson, Torbjörn, Lindskog, Maria, Malmberg, Jesper, Jirholt, Johan, Krutrök, Nina, Ramnegård, Marie, Brännström, Marie, Lundqvist, Anders, Lepistö, Matti, Aagaard, Anna, McPheat, Jane, Hansson, Eva L, Chen, Rongfeng, Xiong, Yao, Hansson, Thomas G, Narjes, Frank
Published in ACS medicinal chemistry letters (13.06.2019)

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Development of an ELISA for High-Throughput Screening of Inhibitors of Cdk5-Mediated PPARγ Phosphorylation

Development of an ELISA for High-Throughput Screening of Inhibitors of Cdk5-Mediated PPARγ Phosphorylation

by Prokoph, Nina, Ormö, Mats, O'Mahony, Gavin, Hogner, Anders, McPheat, Jane, Karlsson, Ulla, Holmberg Schiavone, Lovisa, Liu, Jianming
Published in Assay and drug development technologies (01.05.2016)

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Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper17 (TH17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR[gamma]

Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper17 (TH17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR[gamma]

by Olsson, Roine I, Xue, Yafeng, vonBerg, Stefan, Aagaard, Anna, McPheat, Jane, Hansson, Eva L, Bernstrom, Jenny, Hansson, Pia, Jirholt, Johan, Grindebacke, Hanna, Leffler, Agnes, Chen, Rongfeng, Xiong, Yao, Ge, Hongbin, Hansson, Thomas G, Narjes, Frank
Published in ChemMedChem (01.01.2016)

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Back Cover: Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper17 (TH17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR[gamma]

Back Cover: Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper17 (TH17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR[gamma]

by Olsson, Roine I, Xue, Yafeng, vonBerg, Stefan, Aagaard, Anna, McPheat, Jane, Hansson, Eva L, Bernstrom, Jenny, Hansson, Pia, Jirholt, Johan, Grindebacke, Hanna, Leffler, Agnes, Chen, Rongfeng, Xiong, Yao, Ge, Hongbin, Hansson, Thomas G, Narjes, Frank
Published in ChemMedChem (01.01.2016)

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Back Cover: Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor RORγ (ChemMedChem 2/2016)

Back Cover: Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor RORγ (ChemMedChem 2/2016)

by Olsson, Roine I., Xue, Yafeng, von Berg, Stefan, Aagaard, Anna, McPheat, Jane, Hansson, Eva L., Bernström, Jenny, Hansson, Pia, Jirholt, Johan, Grindebacke, Hanna, Leffler, Agnes, Chen, Rongfeng, Xiong, Yao, Ge, Hongbin, Hansson, Thomas G., Narjes, Frank
Published in ChemMedChem (01.01.2016)

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A serendipitously identified novel small molecule procoagulant compound giving rise to a high-throughput screening assay based on human plasma

A serendipitously identified novel small molecule procoagulant compound giving rise to a high-throughput screening assay based on human plasma

by Gustafsson, David, Nielsen, Sofi, McPheat, Jane, Wågberg, Fredrik, Kaspersson, Karin, Rohman, Mattias, Ulander, Johan, Fex, Tomas, Fjellström, Ola, Deinum, Johanna
Published in Thrombosis research (01.08.2013)

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Targeted Integration of the Ren-1D Locus in Mouse Embryonic Stem Cells

Targeted Integration of the Ren-1D Locus in Mouse Embryonic Stem Cells

by Christopher C. J. Miller, McPheat, Jane C., Potts, Wendy J.
Published in Proceedings of the National Academy of Sciences - PNAS (01.06.1992)

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Evaluation of human liver slices and reporter gene assays as systems for predicting the cytochrome P450 induction potential of drugs in vivo in humans

Evaluation of human liver slices and reporter gene assays as systems for predicting the cytochrome P450 induction potential of drugs in vivo in humans

by PERSSON, Kajsa P, EKEHED, Susanne, OTTER, Charlotta, MAREIKE LUTZ, E. S, MCPHEAT, Jane, MASIMIREMBWA, Collen M, ANDERSSON, Tommy B
Published in Pharmaceutical research (2006)

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Identification of the human ApoAV gene as a novel RORα target gene

Identification of the human ApoAV gene as a novel RORα target gene

by Lind, Ulrika, Nilsson, Tina, McPheat, Jane, Strömstedt, Per-Erik, Bamberg, Krister, Balendran, Clare, Kang, Daiwu
Published in Biochemical and biophysical research communications (29.04.2005)

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Differential interaction of steroid hormone receptors with LXXLL motifs in SRC-1a depends on residues flanking the motif

Differential interaction of steroid hormone receptors with LXXLL motifs in SRC-1a depends on residues flanking the motif

by Needham, Maurice, Raines, Stephanie, McPheat, Jane, Stacey, Clare, Ellston, Jonathan, Hoare, Susan, Parker, Malcolm
Published in The Journal of steroid biochemistry and molecular biology (01.01.2000)

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Identification of the human ApoAV gene as a novel RORalpha target gene

Identification of the human ApoAV gene as a novel RORalpha target gene

by Lind, Ulrika, Nilsson, Tina, McPheat, Jane, Strömstedt, Per-Erik, Bamberg, Krister, Balendran, Clare, Kang, Daiwu
Published in Biochemical and biophysical research communications (29.04.2005)

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Identification of the human ApoAV gene as a novel ROR{alpha} target gene

Identification of the human ApoAV gene as a novel ROR{alpha} target gene

by Lind, Ulrika, Nilsson, Tina, McPheat, Jane, Stroemstedt, Per-Erik, Bamberg, Krister, Balendran, Clare, Kang, Daiwu
Published in Biochemical and biophysical research communications (29.04.2005)

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Study of the interaction of the medium chain μ2 subunit of the clathrin-associated adapter protein complex 2 with cytotoxic T-lymphocyte antigen 4 and CD28

Study of the interaction of the medium chain μ2 subunit of the clathrin-associated adapter protein complex 2 with cytotoxic T-lymphocyte antigen 4 and CD28

by FOLLOWS, Emily R., McPHEAT, Jane C., MINSHULL, Claire, MOORE, Nel C., PAUPTIT, Richard A., ROWSELL, Siân, STACEY, Claire L., STANWAY, Judith J., TAYLOR, Ian W.F., ABBOTT, W. Mark
Published in Biochemical journal (15.10.2001)

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Study of the interaction of the medium chain μ2 subunit of the clathrin-associated adapter protein complex 2 with cytotoxic T-lymphocyte antigen 4 and CD28

Study of the interaction of the medium chain μ2 subunit of the clathrin-associated adapter protein complex 2 with cytotoxic T-lymphocyte antigen 4 and CD28

by FOLLOWS, Emily R., McPHEAT, Jane C., MINSHULL, Claire, MOORE, Nel C., PAUPTIT, Richard A., ROWSELL, Siân, STACEY, Claire L., STANWAY, Judith J., TAYLOR, Ian W. F., ABBOTT, W. Mark
Published in Biochemical journal (15.10.2001)

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