Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis
Lee, Whasil, Nims, Robert J, Savadipour, Alireza, Zhang, Qiaojuan, Leddy, Holly A, Liu, Fang, McNulty, Amy L, Chen, Yong, Guilak, Farshid, Liedtke, Wolfgang B
Published in Proceedings of the National Academy of Sciences - PNAS (30.03.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (30.03.2021)
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Journal Article
Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage
Lee, Whasil, Leddy, Holly A, Chen, Yong, Lee, Suk Hee, Zelenski, Nicole A, McNulty, Amy L, Wu, Jason, Beicker, Kellie N, Coles, Jeffrey, Zauscher, Stefan, Grandl, Jörg, Sachs, Frederick, Guilak, Farshid, Liedtke, Wolfgang B
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2014)
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Journal Article
TRPV4 as a therapeutic target for joint diseases
McNulty, Amy L., Leddy, Holly A., Liedtke, Wolfgang, Guilak, Farshid
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.04.2015)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.04.2015)
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Journal Article
Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis
O'Conor, Christopher J, Ramalingam, Sendhilnathan, Zelenski, Nicole A, Benefield, Halei C, Rigo, Isaura, Little, Dianne, Wu, Chia-Lung, Chen, Di, Liedtke, Wolfgang, McNulty, Amy L, Guilak, Farshid
Published in Scientific reports (08.07.2016)
Published in Scientific reports (08.07.2016)
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Journal Article
Programmable Deuteration of Indoles via Reverse Deuterium Exchange
Fitzgerald, Liam S., McNulty, Rachael L., Greener, Andrew, O’Duill, Miriam L.
Published in Journal of organic chemistry (04.08.2023)
Published in Journal of organic chemistry (04.08.2023)
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Journal Article
Osteoarthritis year in review 2018: mechanics
DeFrate, L.E., Kim-Wang, S.Y., Englander, Z.A., McNulty, A.L.
Published in Osteoarthritis and cartilage (01.03.2019)
Published in Osteoarthritis and cartilage (01.03.2019)
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Journal Article
Cerebral perfusion, oxygenation and metabolism during exercise in young and elderly individuals
Fisher, James P., Hartwich, Doreen, Seifert, Thomas, Olesen, Niels D., McNulty, Clare L., Nielsen, Henning B., van Lieshout, Johannes J., Secher, Niels H.
Published in The Journal of physiology (01.04.2013)
Published in The Journal of physiology (01.04.2013)
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Journal Article
Relationship between T1rho Magnetic Resonance Imaging, Synovial Fluid Biomarkers, and the Biochemical and Biomechanical Properties of Cartilage
C. Hatcher, Courtney, T. Collins, Amber, Y. Kim, Sophia, C. Michel, Lindsey, C. Mostertz III, William, N. Ziemian, Sophia, E. Spritzer, Charles, Guilak, Farshid, E. DeFrate, Louis, L. McNulty, Amy
Published in Journal of biomechanics (11.04.2017)
Published in Journal of biomechanics (11.04.2017)
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Journal Article
Immune cell profiles in synovial fluid after anterior cruciate ligament and meniscus injuries
Kim-Wang, Sophia Y, Holt, Abigail G, McGowan, Alyssa M, Danyluk, Stephanie T, Goode, Adam P, Lau, Brian C, Toth, Alison P, Wittstein, Jocelyn R, DeFrate, Louis E, Yi, John S, McNulty, Amy L
Published in Arthritis research & therapy (04.11.2021)
Published in Arthritis research & therapy (04.11.2021)
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Journal Article
Temporomandibular joint pain: A critical role for Trpv4 in the trigeminal ganglion
Chen, Yong, Williams, Susan H., McNulty, Amy L., Hong, Ji Hee, Lee, Suk Hee, Rothfusz, Nicole E., Parekh, Puja K., Moore, Carlene, Gereau, Robert W., Taylor, Andrea B., Wang, Fan, Guilak, Farshid, Liedtke, Wolfgang
Published in Pain (Amsterdam) (01.08.2013)
Published in Pain (Amsterdam) (01.08.2013)
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Journal Article
Blood in the joint: effects of hemarthrosis on meniscus health and repair techniques
Lyons, L.P., Weinberg, J.B., Wittstein, J.R., McNulty, A.L.
Published in Osteoarthritis and cartilage (01.04.2021)
Published in Osteoarthritis and cartilage (01.04.2021)
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Journal Article
Interleukin-1, tumor necrosis factor-alpha, and transforming growth factor-beta 1 and integrative meniscal repair: influences on meniscal cell proliferation and migration
Riera, Katherine M, Rothfusz, Nicole E, Wilusz, Rebecca E, Weinberg, J B, Guilak, Farshid, McNulty, Amy L
Published in Arthritis research & therapy (01.01.2011)
Published in Arthritis research & therapy (01.01.2011)
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Journal Article
A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues
Nims, Robert J, Pferdehirt, Lara, Ho, Noelani B, Savadipour, Alireza, Lorentz, Jeremiah, Sohi, Sima, Kassab, Jordan, Ross, Alison K, O'Conor, Christopher J, Liedtke, Wolfgang B, Zhang, Bo, McNulty, Amy L, Guilak, Farshid
Published in Science advances (01.01.2021)
Published in Science advances (01.01.2021)
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Journal Article
Preventive Intervention for Living Donor Psychosocial Outcomes: Feasibility and Efficacy in a Randomized Controlled Trial
Dew, M. A., DiMartini, A. F., DeVito Dabbs, A. J., Zuckoff, A., Tan, H. P., McNulty, M. L., Switzer, G. E., Fox, K. R., Greenhouse, J. B., Humar, A.
Published in American journal of transplantation (01.10.2013)
Published in American journal of transplantation (01.10.2013)
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Journal Article
A Tale of Two Loads: Modulation of IL-1 Induced Inflammatory Responses of Meniscal Cells in Two Models of Dynamic Physiologic Loading
Andress, Benjamin D, Irwin, Rebecca M, Puranam, Ishaan, Hoffman, Brenton D, McNulty, Amy L
Published in Frontiers in bioengineering and biotechnology (01.03.2022)
Published in Frontiers in bioengineering and biotechnology (01.03.2022)
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Journal Article
The Effects of Adipokines on Cartilage and Meniscus Catabolism
McNulty, Amy L., Miller, Michael R., O'Connor, Shannon K., Guilak, Farshid
Published in Connective tissue research (01.12.2011)
Published in Connective tissue research (01.12.2011)
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Journal Article