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Takebe, Yutaka, Saucedo, Carrie J, Lund, Garry, Uenishi, Rie, Hase, Saiki, Tsuchiura, Takayo, Kneteman, Norman, Ramessar, Koreen, Tyrrell, D Lorne J, Shirakura, Masayuki, Wakita, Takaji, McMahon, James B, O'Keefe, Barry R
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Published in PloS one (21.05.2013)
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Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae
O'KEEFE, Barry R, GIOMARELLI, Barbara, MCCRAY, Paul B, BARNARD, Dale L, SHENOY, Shilpa R, CHAN, Paul K. S, MCMAHON, James B, PALMER, Kenneth E, BARNETT, Brian W, MEYERHOLZ, David K, WOHLFORD-LENANE, Christine L
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Identification of an Inhibitor of the EWS-FLI1 Oncogenic Transcription Factor by High-Throughput Screening
Grohar, Patrick J., Woldemichael, Girma M., Griffin, Laurie B., Mendoza, Arnulfo, Chen, Qing-Rong, Yeung, Choh, Currier, Duane G., Davis, Sean, Khanna, Chand, Khan, Javed, McMahon, James B., Helman, Lee J.
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Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component
O'Keefe, Barry R, Vojdani, Fakhrieh, Buffa, Viviana, Shattock, Robin J, Montefiori, David C, Bakke, James, Mirsalis, Jon, d'Andrea, Anna-Lisa, Hume, Steven D, Bratcher, Barry, Saucedo, Carrie J, McMahon, James B, Pogue, Gregory P, Palmer, Kenneth E
Published in Proceedings of the National Academy of Sciences - PNAS (14.04.2009)
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The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus
Garrison, Aura R., Giomarelli, Barbara G., Lear-Rooney, Calli M., Saucedo, Carrie J., Yellayi, Srikanth, Krumpe, Lauren R.H., Rose, Maura, Paragas, Jason, Bray, Mike, Olinger, Gene G., McMahon, James B., Huggins, John, O’Keefe, Barry R.
Published in Antiviral research (01.12.2014)
Published in Antiviral research (01.12.2014)
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Isolation and Characterization of Griffithsin, a Novel HIV-inactivating Protein, from the Red Alga Griffithsia sp.
Mori, Toshiyuki, O'Keefe, Barry R., Sowder, Raymond C., Bringans, Scott, Gardella, Roberta, Berg, Shannon, Cochran, Pamela, Turpin, Jim A., Buckheit, Robert W., McMahon, James B., Boyd, Michael R.
Published in The Journal of biological chemistry (11.03.2005)
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Stellettapeptins A and B, HIV-inhibitory cyclic depsipeptides from the marine sponge Stelletta sp
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Published in Tetrahedron letters (08.07.2015)
Published in Tetrahedron letters (08.07.2015)
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Monomerization of Viral Entry Inhibitor Griffithsin Elucidates the Relationship between Multivalent Binding to Carbohydrates and anti-HIV Activity
Moulaei, Tinoush, Shenoy, Shilpa R., Giomarelli, Barbara, Thomas, Cheryl, McMahon, James B., Dauter, Zbigniew, O'Keefe, Barry R., Wlodawer, Alexander
Published in Structure (London) (08.09.2010)
Published in Structure (London) (08.09.2010)
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Isobutylhydroxyamides from the Pericarp of Nepalese Zanthoxylum armatum Inhibit NF1-Defective Tumor Cell Line Growth
Devkota, Krishna P, Wilson, Jennifer, Henrich, Curtis J, McMahon, James B, Reilly, Karlyne M, Beutler, John A
Published in Journal of natural products (Washington, D.C.) (25.01.2013)
Published in Journal of natural products (Washington, D.C.) (25.01.2013)
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Isolation, Structural Elucidation, and Absolute Stereochemistry of Enigmazole A, a Cytotoxic Phosphomacrolide from the Papua New Guinea Marine Sponge Cinachyrella enigmatica
Oku, Naoya, Takada, Kentaro, Fuller, Richard W, Wilson, Jennifer A, Peach, Megan L, Pannell, Lewis K, McMahon, James B, Gustafson, Kirk R
Published in Journal of the American Chemical Society (04.08.2010)
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Domain-Swapped Structure of the Potent Antiviral Protein Griffithsin and Its Mode of Carbohydrate Binding
Ziółkowska, Natasza E., O'Keefe, Barry R., Mori, Toshiyuki, Zhu, Charles, Giomarelli, Barbara, Vojdani, Fakhrieh, Palmer, Kenneth E., McMahon, James B., Wlodawer, Alexander
Published in Structure (London) (01.07.2006)
Published in Structure (London) (01.07.2006)
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Binding of the Mannose-Specific Lectin, Griffithsin, to HIV-1 gp120 Exposes the CD4-Binding Site
BANKOLEDI ALEXANDRE, Kabamba, GRAY, Elin S, PANTOPHLET, Ralph, MOORE, Penny L, MCMAHON, James B, CHAKAUYA, Ereck, O'KEEFE, Barry R, CHIKWAMBA, Rachel, MORRIS, Lynn
Published in Journal of Virology (01.09.2011)
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Engineering soya bean seeds as a scalable platform to produce cyanovirin‐N, a non‐ARV microbicide against HIV
O'Keefe, Barry R., Murad, André M., Vianna, Giovanni R., Ramessar, Koreen, Saucedo, Carrie J., Wilson, Jennifer, Buckheit, Karen W., Cunha, Nicolau B., Araújo, Ana Claudia G., Lacorte, Cristiano C., Madeira, Luisa, McMahon, James B., Rech, Elibio L.
Published in Plant biotechnology journal (01.09.2015)
Published in Plant biotechnology journal (01.09.2015)
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Erioflorin stabilizes the tumor suppressor Pdcd4 by inhibiting its interaction with the E3-ligase β-TrCP1
Blees, Johanna S, Bokesch, Heidi R, Rübsamen, Daniela, Schulz, Kathrin, Milke, Larissa, Bajer, Magdalena M, Gustafson, Kirk R, Henrich, Curtis J, McMahon, James B, Colburn, Nancy H, Schmid, Tobias, Brüne, Bernhard
Published in PloS one (02.10.2012)
Published in PloS one (02.10.2012)
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T7 lytic phage-displayed peptide libraries exhibit less sequence bias than M13 filamentous phage-displayed peptide libraries
Krumpe, Lauren R. H., Atkinson, Andrew J., Smythers, Gary W., Kandel, Andrea, Schumacher, Kathryn M., McMahon, James B., Makowski, Lee, Mori, Toshiyuki
Published in Proteomics (Weinheim) (01.08.2006)
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Lack of a Functional VHL Gene Product Sensitizes Renal Cell Carcinoma Cells to the Apoptotic Effects of the Protein Synthesis Inhibitor Verrucarin A
Woldemichael, Girma M, Turbyville, Thomas J, Vasselli, James R, Linehan, W. Marston, McMahon, James B
Published in Neoplasia (New York, N.Y.) (01.08.2012)
Published in Neoplasia (New York, N.Y.) (01.08.2012)
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New inhibitors of ABCG2 identified by high-throughput screening
Henrich, Curtis J, Robey, Robert W, Bokesch, Heidi R, Bates, Susan E, Shukla, Suneet, Ambudkar, Suresh V, Dean, Michael, McMahon, James B
Published in Molecular cancer therapeutics (01.12.2007)
Published in Molecular cancer therapeutics (01.12.2007)
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Tricyclic guanidine alkaloids from the marine sponge Acanthella cavernosa that stabilize the tumor suppressor PDCD4
Grkovic, Tanja, Blees, Johanna S, Bayer, Magdalena M, Colburn, Nancy H, Thomas, Cheryl L, Henrich, Curtis J, Peach, Megan L, McMahon, James B, Schmid, Tobias, Gustafson, Kirk R
Published in Marine drugs (21.08.2014)
Published in Marine drugs (21.08.2014)
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