Targeting interleukins for the treatment of inflammatory bowel disease-what lies beyond anti-TNF therapy?
McLean, Mairi H, Neurath, Markus F, Durum, Scott K
Published in Inflammatory bowel diseases (01.02.2014)
Published in Inflammatory bowel diseases (01.02.2014)
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Journal Article
Interleukin-27 Regulates the Function of the Gastrointestinal Epithelial Barrier in a Human Tissue-Derived Organoid Model
Brice, Daniel P, Murray, Graeme I, Wilson, Heather M, Porter, Ross J, Berry, Susan, Durum, Scott K, McLean, Mairi H
Published in Biology (Basel, Switzerland) (01.03.2022)
Published in Biology (Basel, Switzerland) (01.03.2022)
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Journal Article
Clonal Transitions and Phenotypic Evolution in Barrett’s Esophagus
Evans, James A., Carlotti, Emanuela, Lin, Meng-Lay, Hackett, Richard J., Haughey, Magnus J., Passman, Adam M., Dunn, Lorna, Elia, George, Porter, Ross J., McLean, Mairi H., Hughes, Frances, ChinAleong, Joanne, Woodland, Philip, Preston, Sean L., Griffin, S. Michael, Lovat, Laurence, Rodriguez-Justo, Manuel, Huang, Weini, Wright, Nicholas A., Jansen, Marnix, McDonald, Stuart A.C.
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2022)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2022)
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Journal Article
Evaluation of the prescribing decision support system Synonyms in a primary care setting: a mixed-method study
Robertson, Lindsay A, McLean, Mairi-Anne, Montgomery Sardar, Colette, Bryson, Graeme, Kurdi, Amanj
Published in The International journal of pharmacy practice (01.10.2020)
Published in The International journal of pharmacy practice (01.10.2020)
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Journal Article
IL-27 induces an IFN-like signature in murine macrophages which in turn modulate colonic epithelium
Andrews, Caroline, McLean, Mairi H, Hixon, Julie A, Pontejo, Sergio M, Starr, Tregei, Malo, Courtney, Cam, Margaret, Ridnour, Lisa, Hickman, Heather, Steele-Mortimer, Olivia, Wink, David A, Young, Howard A, McVicar, Daniel W, Li, Wenqing, Durum, Scott K
Published in Frontiers in immunology (20.04.2023)
Published in Frontiers in immunology (20.04.2023)
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Journal Article
Subcellular Epithelial HMGB1 Expression Is Associated with Colorectal Neoplastic Progression, Male Sex, Mismatch Repair Protein Expression, Lymph Node Positivity, and an 'Immune Cold' Phenotype Associated with Poor Survival
Porter, Ross J, Murray, Graeme I, Hapca, Sandra, Hay, Andrew, Craig, Stephanie G, Humphries, Matthew P, James, Jacqueline A, Salto-Tellez, Manuel, Brice, Daniel P, Berry, Susan H, McLean, Mairi H
Published in Cancers (20.03.2023)
Published in Cancers (20.03.2023)
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Journal Article
Interleukin-27 Is a Potential Rescue Therapy for Acute Severe Colitis Through Interleukin-10-Dependent, T-Cell-Independent Attenuation of Colonic Mucosal Innate Immune Responses
McLean, Mairi H, Andrews, Caroline, Hanson, Miranda L, Baseler, Walter A, Anver, Miriam R, Senkevitch, Emilee, Staniszewska, Aleksandra K, Smith, Christopher, Davies, Luke C, Hixon, Julie, Li, Wenqeng, Shen, Wei, Steidler, Lothar, Durum, Scott K
Published in Inflammatory bowel diseases (01.11.2017)
Published in Inflammatory bowel diseases (01.11.2017)
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Journal Article
Increase in NF-κB Binding Affinity of the Variant C Allele of the Toll-Like Receptor 9 -1237T/C Polymorphism Is Associated with Helicobacter pylori-Induced Gastric Disease
Ng, Mike Tsz Hin, van't Hof, Rob, Crockett, Julie C, Hope, Mairi E, Berry, Susan, Thomson, John, McLean, Mairi H, McColl, Kenneth E.L, El-Omar, Emad M, Hold, Georgina L
Published in Infection and Immunity (01.03.2010)
Published in Infection and Immunity (01.03.2010)
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Journal Article
IL-22-Expressing Murine Lymphocytes Display Plasticity and Pathogenicity in Reporter Mice
Shen, Wei, Hixon, Julie A, McLean, Mairi H, Li, Wen Qing, Durum, Scott K
Published in Frontiers in immunology (19.01.2016)
Published in Frontiers in immunology (19.01.2016)
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Journal Article
Colonic epithelial cathelicidin (LL‐37) expression intensity is associated with progression of colorectal cancer and presence of CD8+ T cell infiltrate
Porter, Ross J, Murray, Graeme I, Alnabulsi, Abdo, Humphries, Matthew P, James, Jacqueline A, Salto‐Tellez, Manuel, Craig, Stephanie G, Wang, Ji M, Yoshimura, Teizo, McLean, Mairi H
Published in The journal of pathology. Clinical research (01.09.2021)
Published in The journal of pathology. Clinical research (01.09.2021)
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Journal Article
The matrix metalloproteinase/tissue inhibitor of matrix metalloproteinase profile in colorectal polyp cancers
Jeffery, Natalie, McLean, Mairi H, El-Omar, Emad M, Murray, Graeme I
Published in Histopathology (01.06.2009)
Published in Histopathology (01.06.2009)
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Journal Article
137 Intra-Luminal Interleukin (IL)-27 Ameliorates Acute Murine TNBS Colitis - A Potential Future Human Therapeutic for Inflammatory Bowel Disease?
McLean, Mairi H, Hanson, Miranda L, Steidler, Lothar, Anver, Miriam R, Shen, Wei, Durum, Scott K
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
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Journal Article
Mo1704 Intra-Luminal Interleukin (IL)-27 Attenuates Acute Murine 2,4,6-Trinitrobenzene Sulfonic Acid (TNBS) Colitis and Is Associated With Down-Regulation of Mucosal Humoral Response
McLean, Mairi H, Gold, Bert, Golubeva, Yelena, Wu, Xiaolin, Sun, David, Anver, Miriam R, Hanson, Miranda L, Steidler, Lothar, Durum, Scott K
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2014)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2014)
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Journal Article