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Published in Proceedings of the National Academy of Sciences - PNAS (30.07.2013)
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Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974
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Published in Proceedings of the National Academy of Sciences - PNAS (10.12.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (10.12.2013)
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Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers
Hoffman, Gregory R., Rahal, Rami, Buxton, Frank, Xiang, Kay, McAllister, Gregory, Frias, Elizabeth, Bagdasarian, Linda, Huber, Janina, Lindeman, Alicia, Chen, Dongshu, Romero, Rodrigo, Ramadan, Nadire, Phadke, Tanushree, Haas, Kristy, Jaskelioff, Mariela, Wilson, Boris G., Meyer, Matthew J., Saenz-Vash, Veronica, Zhai, Huili, Myer, Vic E., Porter, Jeffrey A., Keen, Nicholas, McLaughlin, Margaret E., Mickanin, Craig, Roberts, Charles W. M., Stegmeier, Frank, Jagani, Zainab
Published in Proceedings of the National Academy of Sciences - PNAS (25.02.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (25.02.2014)
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PCA062, a P-cadherin Targeting Antibody-Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin-expressing Malignancies
Sheng, Qing, D'Alessio, Joseph A, Menezes, Daniel L, Karim, Christopher, Tang, Yan, Tam, Angela, Clark, Suzanna, Ying, Chi, Connor, Anu, Mansfield, Keith G, Rondeau, Jean-Michel, Ghoddusi, Majid, Geyer, Felipe C, Gu, Jane, McLaughlin, Margaret E, Newcombe, Rick, Elliot, GiNell, Tschantz, William R, Lehmann, Sylvie, Fanton, Christie P, Miller, Kathy, Huber, Thomas, Rendahl, Katherine G, Jeffry, Ursula, Pryer, Nancy K, Lees, Emma, Kwon, Paul, Abraham, Judith A, Damiano, Jason S, Abrams, Tinya J
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Published in Molecular cancer therapeutics (01.07.2021)
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Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family
Viatour, Patrick, Somervaille, Tim C, Venkatasubrahmanyam, Shivkumar, Kogan, Scott, McLaughlin, Margaret E, Weissman, Irving L, Butte, Atul J, Passegué, Emmanuelle, Sage, Julien
Published in Cell stem cell (09.10.2008)
Published in Cell stem cell (09.10.2008)
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Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming
McLaughlin-Drubin, Margaret E, Crum, Christopher P, Münger, Karl
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2011)
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Maintenance of adenomatous polyposis coli (APC)-mutant colorectal cancer is dependent on Wnt/β-catenin signaling
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Published in Proceedings of the National Academy of Sciences - PNAS (11.10.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (11.10.2011)
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discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer
Herfs, Michael, Yamamoto, Yusuke, Laury, Anna, Wang, Xia, Nucci, Marisa R, McLaughlin-Drubin, Margaret E, Münger, Karl, Feldman, Sarah, McKeon, Frank D, Xian, Wa, Crum, Christopher P
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Published in Proceedings of the National Academy of Sciences - PNAS (26.06.2012)
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MacPherson, David, Sage, Julien, Kim, Teresa, Ho, Dennis, McLaughlin, Margaret E, Jacks, Tyler
Published in Genes & development (15.07.2004)
Published in Genes & development (15.07.2004)
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ROS fusion tyrosine kinase activates a SH2 domain-containing phosphatase-2/phosphatidylinositol 3-kinase/mammalian target of rapamycin signaling axis to form glioblastoma in mice
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Published in Cancer research (Chicago, Ill.) (01.08.2006)
Published in Cancer research (Chicago, Ill.) (01.08.2006)
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Determinants of Wnt/β-catenin pathway dependency in colorectal cancer
Scholer-Dahirel, Alix, McLaughlin, Margaret E.
Published in Cell cycle (Georgetown, Tex.) (01.01.2012)
Published in Cell cycle (Georgetown, Tex.) (01.01.2012)
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Mouse Models of Tumor Development in Neurofibromatosis Type 1
Cichowski, Karen, Shih, T. Shane, Schmitt, Earlene, Santiago, Sabrina, Reilly, Karlyne, McLaughlin, Margaret E., Bronson, Roderick T., Jacks, Tyler
Published in Science (American Association for the Advancement of Science) (10.12.1999)
Published in Science (American Association for the Advancement of Science) (10.12.1999)
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Human Papillomavirus Type 16 E7 Oncoprotein Associates with E2F6
McLaughlin-Drubin, Margaret E., Huh, Kyung-Won, Münger, Karl
Published in Journal of Virology (01.09.2008)
Published in Journal of Virology (01.09.2008)
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Nf2 tumor suppressor regulates cell-cell adhesion during tissue fusion
McLaughlin, Margaret E, Kruger, Genevieve M, Slocum, Kelly L, Crowley, Denise, Michaud, Norman A, Huang, Jennifer, Magendantz, Margaret, Jacks, Tyler
Published in Proceedings of the National Academy of Sciences - PNAS (27.02.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (27.02.2007)
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Rodon, Jordi, Argilés, Guillem, Connolly, Roisin M., Vaishampayan, Ulka, de Jonge, Maja, Garralda, Elena, Giannakis, Marios, Smith, David C., Dobson, Jason R., McLaughlin, Margaret E., Seroutou, Abdelkader, Ji, Yan, Morawiak, Jennifer, Moody, Susan E., Janku, Filip
Published in British journal of cancer (06.07.2021)
Published in British journal of cancer (06.07.2021)
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Enhanced targeting of CML stem and progenitor cells by inhibition of porcupine acyltransferase in combination with TKI
Agarwal, Puneet, Zhang, Bin, Ho, Yinwei, Cook, Amy, Li, Ling, Mikhail, Fady M., Wang, Youzhen, McLaughlin, Margaret E., Bhatia, Ravi
Published in Blood (23.02.2017)
Published in Blood (23.02.2017)
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Jacks, Tyler, Ventura, Andrea, Kirsch, David G, McLaughlin, Margaret E, Tuveson, David A, Grimm, Jan, Lintault, Laura, Newman, Jamie, Reczek, Elizabeth E, Weissleder, Ralph
Published in Nature (08.02.2007)
Published in Nature (08.02.2007)
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