Genome Organization Drives Chromosome Fragility
Canela, Andres, Maman, Yaakov, Jung, Seolkyoung, Wong, Nancy, Callen, Elsa, Day, Amanda, Kieffer-Kwon, Kyong-Rim, Pekowska, Aleksandra, Zhang, Hongliang, Rao, Suhas S.P., Huang, Su-Chen, Mckinnon, Peter J., Aplan, Peter D., Pommier, Yves, Aiden, Erez Lieberman, Casellas, Rafael, Nussenzweig, André
Published in Cell (27.07.2017)
Published in Cell (27.07.2017)
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DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation
Simsek, Deniz, Brunet, Erika, Wong, Sunnie Yan-Wai, Katyal, Sachin, Gao, Yankun, McKinnon, Peter J, Lou, Jacqueline, Zhang, Lei, Li, James, Rebar, Edward J, Gregory, Philip D, Holmes, Michael C, Jasin, Maria
Published in PLoS genetics (01.06.2011)
Published in PLoS genetics (01.06.2011)
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Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression
Larson, Jon D., Kasper, Lawryn H., Paugh, Barbara S., Jin, Hongjian, Wu, Gang, Kwon, Chang-Hyuk, Fan, Yiping, Shaw, Timothy I., Silveira, André B., Qu, Chunxu, Xu, Raymond, Zhu, Xiaoyan, Zhang, Junyuan, Russell, Helen R., Peters, Jennifer L., Finkelstein, David, Xu, Beisi, Lin, Tong, Tinkle, Christopher L., Patay, Zoltan, Onar-Thomas, Arzu, Pounds, Stanley B., McKinnon, Peter J., Ellison, David W., Zhang, Jinghui, Baker, Suzanne J.
Published in Cancer cell (14.01.2019)
Published in Cancer cell (14.01.2019)
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53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination
Callen, Elsa, Zong, Dali, Wu, Wei, Wong, Nancy, Stanlie, Andre, Ishikawa, Momoko, Pavani, Raphael, Dumitrache, Lavinia C., Byrum, Andrea K., Mendez-Dorantes, Carlos, Martinez, Paula, Canela, Andres, Maman, Yaakov, Day, Amanda, Kruhlak, Michael J., Blasco, Maria A., Stark, Jeremy M., Mosammaparast, Nima, McKinnon, Peter J., Nussenzweig, André
Published in Molecular cell (02.01.2020)
Published in Molecular cell (02.01.2020)
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The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number
Lavado, Alfonso, Park, Jun Young, Paré, Joshua, Finkelstein, David, Pan, Haitao, Xu, Beisi, Fan, Yiping, Kumar, Ram Parikshan, Neale, Geoffrey, Kwak, Young Don, McKinnon, Peter J., Johnson, Randy L., Cao, Xinwei
Published in Developmental cell (03.12.2018)
Published in Developmental cell (03.12.2018)
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Polynucleotide kinase-phosphatase (PNKP) mutations and neurologic disease
Dumitrache, Lavinia C., McKinnon, Peter J.
Published in Mechanisms of ageing and development (01.01.2017)
Published in Mechanisms of ageing and development (01.01.2017)
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Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair
Aditi, Downing, Susanna M., Schreiner, Patrick A., Kwak, Young Don, Li, Yang, Shaw, Timothy I., Russell, Helen R., McKinnon, Peter J.
Published in Neuron (Cambridge, Mass.) (15.12.2021)
Published in Neuron (Cambridge, Mass.) (15.12.2021)
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XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia
Hoch, Nicolas C., Hanzlikova, Hana, Rulten, Stuart L., Tétreault, Martine, Komulainen, Emilia, Ju, Limei, Hornyak, Peter, Zeng, Zhihong, Gittens, William, Rey, Stephanie A., Staras, Kevin, Mancini, Grazia M. S., McKinnon, Peter J., Wang, Zhao-Qi, Wagner, Justin D., Yoon, Grace, Caldecott, Keith W.
Published in Nature (London) (05.01.2017)
Published in Nature (London) (05.01.2017)
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A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging
Murga, Matilde, Fernandez-Capetillo, Oscar, Bunting, Samuel, Montaña, Maria F, Soria, Rebeca, Mulero, Francisca, Cañamero, Marta, Lee, Youngsoo, McKinnon, Peter J, Nussenzweig, Andre
Published in Nature genetics (01.08.2009)
Published in Nature genetics (01.08.2009)
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Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion
Rangachari, Manu, Zhu, Chen, Sakuishi, Kaori, Xiao, Sheng, Karman, Jozsef, Chen, Andrew, Angin, Mathieu, Wakeham, Andrew, Greenfield, Edward A, Sobel, Raymond A, Okada, Hitoshi, McKinnon, Peter J, Mak, Tak W, Addo, Marylyn M, Anderson, Ana C, Kuchroo, Vijay K
Published in Nature medicine (01.09.2012)
Published in Nature medicine (01.09.2012)
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Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes
Katyal, Sachin, Lee, Youngsoo, Nitiss, Karin C, Downing, Susanna M, Li, Yang, Shimada, Mikio, Zhao, Jingfeng, Russell, Helen R, Petrini, John H J, Nitiss, John L, McKinnon, Peter J
Published in Nature neuroscience (01.06.2014)
Published in Nature neuroscience (01.06.2014)
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