An SCN9A channelopathy causes congenital inability to experience pain
Reimann, Frank, McHale, Duncan P, Valente, Enza Maria, Jafri, Hussain, Al-Gazali, Lihadh, Gribble, Fiona M, Thornton, Gemma, Gorman, Shaun, Williams, Richard, Wood, John N, Nicholas, Adeline K, Roberts, Emma, Mannan, Jovaria, Springell, Kelly, Woods, C. Geoffrey, Cox, James J, Raashid, Yasmin, Karbani, Gulshan, Hamamy, Henan
Published in Nature (14.12.2006)
Published in Nature (14.12.2006)
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Journal Article
A genome-wide screen for variants influencing certolizumab pegol response in a moderate to severe rheumatoid arthritis population
White, Ian R, Kleinstein, Sarah E, Praet, Christophe, Chamberlain, Chris, McHale, Duncan, Maia, Jessica M, Xie, Pingxing, Goldstein, David B, Urban, Thomas J, Shea, Patrick R
Published in PloS one (12.04.2022)
Published in PloS one (12.04.2022)
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Journal Article
Impact of oral administration of single strain Lactococcus lactis spp. cremoris on immune responses to keyhole limpet hemocyanin immunization and gut microbiota: A randomized placebo-controlled trial in healthy volunteers
Saghari, Mahdi, Gal, Pim, Grievink, Hendrika W, Klaassen, Erica S, Itano, Andrea, McHale, Duncan, Moerland, Matthijs
Published in Frontiers in immunology (07.12.2022)
Published in Frontiers in immunology (07.12.2022)
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Journal Article
Dominant Splice Site Mutations in PIK3R1 Cause Hyper IgM Syndrome, Lymphadenopathy and Short Stature
Petrovski, Slavé, Parrott, Roberta E., Roberts, Joseph L., Huang, Hongxiang, Yang, Jialong, Gorentla, Balachandra, Mousallem, Talal, Wang, Endi, Armstrong, Martin, McHale, Duncan, MacIver, Nancie J., Goldstein, David B., Zhong, Xiao-Ping, Buckley, Rebecca H.
Published in Journal of clinical immunology (01.07.2016)
Published in Journal of clinical immunology (01.07.2016)
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Journal Article
A randomized, double-blinded, phase 2 trial of EDP1815, an oral immunomodulatory preparation of Prevotella histicola , in adults with mild-to-moderate plaque psoriasis
Ehst, Benjamin D, Strober, Bruce, Blauvelt, Andrew, Maslin, Douglas, Macaro, Debbie, Carpenter, Nancy, Bodmer, Mark, McHale, Duncan
Published in Frontiers in medicine (15.05.2024)
Published in Frontiers in medicine (15.05.2024)
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Journal Article
Evaluation of single-strain Prevotella histicola on KLH-driven immune responses in healthy volunteers: A randomized controlled trial with EDP1815
Saghari, Mahdi, Gal, Pim, Grievink, Hendrika W., Klaassen, Erica S., Zhuparris, Ahnjili, Itano, Andrea, Bodmer, Mark, McHale, Duncan, Moerland, Matthijs
Published in Medicine in microecology (01.03.2024)
Published in Medicine in microecology (01.03.2024)
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Journal Article
Clinical translation of anti-inflammatory effects of Prevotella histicola in Th1, Th2, and Th17 inflammation
Itano, Andrea, Maslin, Douglas, Ramani, Kritika, Mehraei, Golbarg, Carpenter, Nancy, Cormack, Taylor, Saghari, Mahdi, Moerland, Matthijs, Troy, Erin, Caffry, Will, Wardwell-Scott, Leslie, Abel, Stuart, McHale, Duncan, Bodmer, Mark
Published in Frontiers in medicine (05.05.2023)
Published in Frontiers in medicine (05.05.2023)
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Journal Article
Mutation in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia disease
Burn, John, Barker, William A, Markham, Alex F, Curtis, Ann, Chinnery, Patrick F, Coulthard, Alan, Fey, Constanze, Jackson, Andrew P, Jackson, Margaret J, Bates, David, Curtis, Andrew R.J, McHale, Duncan P, Bindoff, Laurence A, Ince, Paul G, Hay, David, Morris, Christopher M
Published in Nature genetics (01.08.2001)
Published in Nature genetics (01.08.2001)
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Journal Article
The second locus for autosomal recessive primary microcephaly (MCPH2) maps to chromosome 19q13.1-13.2
Roberts, E, Jackson, A P, Carradice, A C, Deeble, V J, Mannan, J, Rashid, Y, Jafri, H, McHale, D P, Markham, A F, Lench, N J, Woods, C G
Published in European journal of human genetics : EJHG (01.10.1999)
Published in European journal of human genetics : EJHG (01.10.1999)
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Journal Article
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
Damgaard, Rune Busk, Walker, Jennifer A., Marco-Casanova, Paola, Morgan, Neil V., Titheradge, Hannah L., Elliott, Paul R., McHale, Duncan, Maher, Eamonn R., McKenzie, Andrew N.J., Komander, David
Published in Cell (25.08.2016)
Published in Cell (25.08.2016)
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Journal Article
Health Insurance Coverage Predicts Health Care Use among Latine Immigrants in Two Policy Contexts
Morrissey, Taryn, Castleberry, Neko Michelle, McHale, Duncan, Sol, Catalina, Dondero, Molly, Yamanis, Thespina
Published in Journal of health care for the poor and underserved (01.05.2024)
Published in Journal of health care for the poor and underserved (01.05.2024)
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Journal Article
Whole-exome sequencing in undiagnosed genetic diseases: interpreting 119 trios
Zhu, Xiaolin, Petrovski, Slavé, Xie, Pingxing, Ruzzo, Elizabeth K., Lu, Yi-Fan, McSweeney, K. Melodi, Ben-Zeev, Bruria, Nissenkorn, Andreea, Anikster, Yair, Oz-Levi, Danit, Dhindsa, Ryan S., Hitomi, Yuki, Schoch, Kelly, Spillmann, Rebecca C., Heimer, Gali, Marek-Yagel, Dina, Tzadok, Michal, Han, Yujun, Worley, Gordon, Goldstein, Jennifer, Jiang, Yong-Hui, Lancet, Doron, Pras, Elon, Shashi, Vandana, McHale, Duncan, Need, Anna C., Goldstein, David B.
Published in Genetics in medicine (01.10.2015)
Published in Genetics in medicine (01.10.2015)
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Journal Article
Pharmacogenetics: Development Issues and Solutions for Safe and Effective Medicines
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Journal Article
Conference Proceeding
Primary Autosomal Recessive Microcephaly (MCPH1) Maps to Chromosome 8p22-pter
Jackson, Andrew P., McHale, Duncan P., Campbell, David A., Jafri, Hussain, Rashid, Yasmin, Mannan, Jovaria, Karbani, Gulshan, Corry, Peter, Levene, Malcolm I., Mueller, Robert F., Markham, Alexander F., Lench, Nicholas J., Woods, C. Geoffrey
Published in American journal of human genetics (01.08.1998)
Published in American journal of human genetics (01.08.1998)
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Journal Article
Tracing investment in drug development for Alzheimer disease
Kodamullil, Alpha Tom, Zekri, Firas, Sood, Meemansa, Hengerer, Bastian, Canard, Luc, McHale, Duncan, Hofmann-Apitius, Martin
Published in Nature reviews. Drug discovery (23.10.2017)
Published in Nature reviews. Drug discovery (23.10.2017)
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Journal Article
Towards the taxonomy of human disease
Hofmann-Apitius, Martin, Alarcón-Riquelme, Marta E., Chamberlain, Chris, McHale, Duncan
Published in Nature reviews. Drug discovery (01.02.2015)
Published in Nature reviews. Drug discovery (01.02.2015)
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Journal Article
Abstract PS11-27: A phase I/II clinical trial of EDP1503 with pembrolizumab for triple-negative breast cancer
Francisco-Anderson, Loise, Shariffudin, Shamira, Gardner, Humphrey, Sandy, Peter, Goldberg, Michael, Kashyap, Shubhra, Abdou, Mary, Sizova, Maria, Kravitz, Valeria, Ponichtera, Holly, Carlson, Mark, Argueta, Shannon, Davitt, Chris, Parameswaran, Pooja, Chisamore, Michael, Bodmer, Mark, McHale, Duncan
Published in Cancer research (Chicago, Ill.) (15.02.2021)
Published in Cancer research (Chicago, Ill.) (15.02.2021)
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