Inhibiting TLR2 activation attenuates amyloid accumulation and glial activation in a mouse model of Alzheimer’s disease
McDonald, Claire L, Hennessy, Edel, Araiz, Ana Rubio, Keogh, Brian, McCormack, William, McGuirk, Peter, Reilly, Mary, Lynch, Marina A
Published in Brain, behavior, and immunity (01.11.2016)
Published in Brain, behavior, and immunity (01.11.2016)
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Myocardial Ischemia/Reperfusion Injury Is Mediated by Leukocytic Toll-Like Receptor-2 and Reduced by Systemic Administration of a Novel Anti-Toll-Like Receptor-2 Antibody
ARSLAN, Fatih, SMEETS, Mirjam B, DE KLEIJN, Dominique P. V, O'NEILL, Luke A. J, KEOGH, Brian, MCGUIRK, Peter, TIMMERS, Leo, TERSTEEG, Claudia, HOEFER, Imo E, DOEVENDANS, Pieter A, PASTERKAMP, Gerard
Published in Circulation (New York, N.Y.) (05.01.2010)
Published in Circulation (New York, N.Y.) (05.01.2010)
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Journal Article
Molecules of infectious agents as immunomodulatory drugs
Lavelle, Ed C, McGuirk, Peter, Mills, Kingston H G
Published in Current topics in medicinal chemistry (01.01.2004)
Published in Current topics in medicinal chemistry (01.01.2004)
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Journal Article
Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis
McGuirk, Peter, McCann, Chantelle, Mills, Kingston H G
Published in The Journal of experimental medicine (21.01.2002)
Published in The Journal of experimental medicine (21.01.2002)
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Journal Article
Identification of TLR2 Signalling Mechanisms Which Contribute to Barrett's and Oesophageal Adenocarcinoma Disease Progression
Flis, Ewelina, Barber, Gillian, Nulty, Ciara, Keogh, Brian, McGuirk, Peter, Anand, Akanksha, O'Sullivan, Jacintha, Quante, Michael, Creagh, Emma M
Published in Cancers (25.04.2021)
Published in Cancers (25.04.2021)
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Journal Article
Treatment With OPN-305, a Humanized Anti-Toll-Like Receptor-2 Antibody, Reduces Myocardial Ischemia/Reperfusion Injury in Pigs
ARSLAN, Fatih, HOUTGRAAF, Jaco H, AKEROYD, Lars, REILLY, Mary, PASTERKAMP, Gerard, DE KLEIJN, Dominique P. V, KEOGH, Brian, KAZEMI, Kushan, DE JONG, Renate, MCCORMACK, William J, O'NEILL, Luke A. J, MCGUIRK, Peter, TIMMERS, Leo, SMEETS, Mirjam B
Published in Circulation. Cardiovascular interventions (01.04.2012)
Published in Circulation. Cardiovascular interventions (01.04.2012)
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A Clinical Study of Tomaralimab (OPN-305), a Toll-like Receptor 2 (TLR-2) Antibody, in Heavily Pre-Treated Transfusion Dependent Patients with Lower Risk Myelodysplastic Syndromes (MDS) That Have Received and Failed on Prior Hypomethylating Agent (HMA) Therapy
Garcia-Manero, Guillermo, Jabbour, Elias J., Konopleva, Marina Y., Daver, Naval G., Borthakur, Gautam, DiNardo, Courtney D., Bose, Prithviraj, Patel, Parita, Komrokji, Rami S., Shastri, Aditi, Roboz, Gail J., Miller, Robert Matthew, Arbe-Barnes, Sarah, Reilly, Mary, McGuirk, Peter, Kearney, Tara, Keogh, Brian, Kantarjian, Hagop M.
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Mechanisms of Disease: the hygiene hypothesis revisited
Guarner, Francisco, Bourdet-Sicard, Raphaëlle, Brandtzaeg, Per, Gill, Harsharnjit S, McGuirk, Peter, van Eden, Willem, Versalovic, James, Weinstock, Joel V, Rook, Graham AW
Published in Nature clinical practice. Gastroenterology & hepatology (01.05.2006)
Published in Nature clinical practice. Gastroenterology & hepatology (01.05.2006)
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Journal Article
Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures
Ultaigh, Sinéad Nic An, Saber, Tajvur P, McCormick, Jennifer, Connolly, Mary, Dellacasagrande, Jerome, Keogh, Brian, McCormack, William, Reilly, Mary, O'Neill, Luke A, McGuirk, Peter, Fearon, Ursula, Veale, Douglas J
Published in Arthritis research & therapy (23.02.2011)
Published in Arthritis research & therapy (23.02.2011)
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Journal Article
Toll-Like Receptor 4-Mediated Innate IL-10 Activates Antigen-Specific Regulatory T Cells and Confers Resistance to Bordetella pertussis by Inhibiting Inflammatory Pathology
Higgins, Sarah C, Lavelle, Ed C, McCann, Chantelle, Keogh, Brian, McNeela, Edel, Byrne, Patricia, O'Gorman, Brian, Jarnicki, Andrew, McGuirk, Peter, Mills, Kingston H. G
Published in The Journal of immunology (1950) (15.09.2003)
Published in The Journal of immunology (1950) (15.09.2003)
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Journal Article
Depletion of NK cells results in disseminating lethal infection with Bordetella pertussis associated with a reduction of antigen‐specific Th1 and enhancement of Th2, but not Tr1 cells
Byrne, Patricia, McGuirk, Peter, Todryk, Stephen, Mills, Kingston H. G.
Published in European Journal of Immunology (01.09.2004)
Published in European Journal of Immunology (01.09.2004)
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Journal Article
Pathogen-specific T Regulatory 1 Cells Induced in the Respiratory Tract by a Bacterial Molecule that Stimulates Interleukin 10 Production by Dendritic Cells: A Novel Strategy for Evasion of Protective T Helper Type 1 Responses by
McGuirk, Peter, McCann, Chantelle, Mills, Kingston H.G.
Published in The Journal of experimental medicine (21.01.2002)
Published in The Journal of experimental medicine (21.01.2002)
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Journal Article
Pathogen-specific T Regulatory 1 Cells Induced in the Respiratory Tract by a Bacterial Molecule that Stimulates Interleukin 10 Production by Dendritic Cells
McGuirk, Peter, McCann, Chantelle, Mills, Kingston H.G.
Published in The Journal of experimental medicine (21.01.2002)
Published in The Journal of experimental medicine (21.01.2002)
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Journal Article
Prevention of experimental colitis by parenteral administration of a pathogen-derived immunomodulatory molecule
Braat, Henri, McGuirk, Peter, Ten Kate, Fiebo J W, Huibregtse, Inge, Dunne, Padraic J, Hommes, Daan W, Van Deventer, Sander J H, Mills, Kingston H G
Published in Gut (01.03.2007)
Published in Gut (01.03.2007)
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