Crystal structure of the SALL4–pomalidomide–cereblon–DDB1 complex
Matyskiela, Mary E., Clayton, Thomas, Zheng, Xinde, Mayne, Christopher, Tran, Eileen, Carpenter, Aaron, Pagarigan, Barbra, McDonald, Joseph, Rolfe, Mark, Hamann, Lawrence G., Lu, Gang, Chamberlain, Philip P.
Published in Nature structural & molecular biology (01.04.2020)
Published in Nature structural & molecular biology (01.04.2020)
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Evolution of Cereblon-Mediated Protein Degradation as a Therapeutic Modality
Chamberlain, Philip P, D’Agostino, Laura A, Ellis, J. Michael, Hansen, Joshua D, Matyskiela, Mary E, McDonald, Joseph J, Riggs, Jennifer R, Hamann, Lawrence G
Published in ACS medicinal chemistry letters (12.12.2019)
Published in ACS medicinal chemistry letters (12.12.2019)
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Discovery of CC-99677, a selective targeted covalent MAPKAPK2 (MK2) inhibitor for autoimmune disorders
Malona, JOHN, CHUAQUI, CLAUDIO, SELETSKY, BORIS M., BEEBE, LISA, CANTIN, SUSAN, KALKEN, DANIEL VAN, FAHNOE, KELLY, WANG, ZHIGANG, BROWNING, BETH, SZABO, HILARY, KOOPMAN, LOUISE A., ORAVECZ, TAMAS, MCDONALD, JOSEPH J., RAMIREZ-VALLE, FRANCISCO, GAUR, RAJULA, MENSAH, KOFI A., THOMAS, MICHAEL, CONNARN, JAMIE N., HU, HAIQING, ALEXANDER, MATTHEW D., CORIN, ALAN F.
Published in Translational research : the journal of laboratory and clinical medicine (01.11.2022)
Published in Translational research : the journal of laboratory and clinical medicine (01.11.2022)
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Predicting the Future Manufacturing Cost of Batteries for Plug-In Vehicles for the U.S. Environmental Protection Agency (EPA) 2017–2025 Light-Duty Greenhouse Gas Standards
Safoutin, Michael, McDonald, Joseph, Ellies, Ben
Published in World electric vehicle journal (06.10.2018)
Published in World electric vehicle journal (06.10.2018)
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Discovery of Selective, Covalent FGFR4 Inhibitors with Antitumor Activity in Models of Hepatocellular Carcinoma
Liu, Haibo, Niu, Deqiang, Tham Sjin, Robert Tjin, Dubrovskiy, Alex, Zhu, Zhendong, McDonald, Joseph J, Fahnoe, Kelly, Wang, Zhigang, Munson, Mark, Scholte, Andrew, Barrague, Matthieu, Fitzgerald, Maria, Liu, Jinyu, Kothe, Michael, Sun, Fangxian, Murtie, Joshua, Ge, Jie, Rocnik, Jennifer, Harvey, Darren, Ospina, Beatriz, Perron, Keli, Zheng, Gang, Shehu, Elvis, D’Agostino, Laura Akullian
Published in ACS medicinal chemistry letters (08.10.2020)
Published in ACS medicinal chemistry letters (08.10.2020)
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Discovery of Potent Inhibitors of Soluble Epoxide Hydrolase by Combinatorial Library Design and Structure-Based Virtual Screening
Xing, Li, McDonald, Joseph J, Kolodziej, Steve A, Kurumbail, Ravi G, Williams, Jennifer M, Warren, Chad J, O’Neal, Janet M, Skepner, Jill E, Roberds, Steven L
Published in Journal of medicinal chemistry (10.03.2011)
Published in Journal of medicinal chemistry (10.03.2011)
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Orally Active MMP-1 Sparing α-Tetrahydropyranyl and α-Piperidinyl Sulfone Matrix Metalloproteinase (MMP) Inhibitors with Efficacy in Cancer, Arthritis, and Cardiovascular Disease
Becker, Daniel P, Barta, Thomas E, Bedell, Louis J, Boehm, Terri L, Bond, Brian R, Carroll, Jeffery, Carron, Chris P, DeCrescenzo, Gary A, Easton, Alan M, Freskos, John N, Funckes-Shippy, Chris L, Heron, Marcia, Hockerman, Susan, Howard, Carol Pearcy, Kiefer, James R, Li, Madeleine H, Mathis, Karl J, McDonald, Joseph J, Mehta, Pramod P, Munie, Grace E, Sunyer, Teresa, Swearingen, Craig A, Villamil, Clara I, Welsch, Dean, Williams, Jennifer M, Yu, Ying, Yao, Jun
Published in Journal of medicinal chemistry (23.09.2010)
Published in Journal of medicinal chemistry (23.09.2010)
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Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents
Kurumbail, Ravi G, Stevens, Anna M, Gierse, James K, McDonald, Joseph J, Stegeman, Roderick A, Pak, Jina Y, Gildehaus, Daniel, iyashiro, Julie M, Penning, Thomas D, Seibert, Karen, Isakson, Peter C, Stallings, William C
Published in Nature (London) (26.12.1996)
Published in Nature (London) (26.12.1996)
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