Punctuated copy number evolution and clonal stasis in triple-negative breast cancer
Gao, Ruli, Davis, Alexander, McDonald, Thomas O, Sei, Emi, Shi, Xiuqing, Wang, Yong, Tsai, Pei-Ching, Casasent, Anna, Waters, Jill, Zhang, Hong, Meric-Bernstam, Funda, Michor, Franziska, Navin, Nicholas E
Published in Nature genetics (01.10.2016)
Published in Nature genetics (01.10.2016)
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Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer
Ge, Jennifer Y, Shu, Shaokun, Kwon, Mijung, Jovanović, Bojana, Murphy, Katherine, Gulvady, Anushree, Fassl, Anne, Trinh, Anne, Kuang, Yanan, Heavey, Grace A, Luoma, Adrienne, Paweletz, Cloud, Thorner, Aaron R, Wucherpfennig, Kai W, Qi, Jun, Brown, Myles, Sicinski, Piotr, McDonald, Thomas O, Pellman, David, Michor, Franziska, Polyak, Kornelia
Published in Nature communications (11.05.2020)
Published in Nature communications (11.05.2020)
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Single-cell heterogeneity of EGFR and CDK4 co-amplification is linked to immune infiltration in glioblastoma
Walentynowicz, Kacper A., Engelhardt, Dalit, Cristea, Simona, Yadav, Shreya, Onubogu, Ugoma, Salatino, Roberto, Maerken, Melanie, Vincentelli, Cristina, Jhaveri, Aashna, Geisberg, Jacob, McDonald, Thomas O., Michor, Franziska, Janiszewska, Michalina
Published in Cell reports (Cambridge) (28.03.2023)
Published in Cell reports (Cambridge) (28.03.2023)
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Imaging dynamic mTORC1 pathway activity in vivo reveals marked shifts that support time-specific inhibitor therapy in AML
Oki, Toshihiko, Mercier, Francois, Kato, Hiroki, Jung, Yookyung, McDonald, Thomas O, Spencer, Joel A, Mazzola, Michael C, van Gastel, Nick, Lin, Charles P, Michor, Franziska, Kitamura, Toshio, Scadden, David T
Published in Nature communications (11.01.2021)
Published in Nature communications (11.01.2021)
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Identification of optimal dosing schedules of dacomitinib and osimertinib for a phase I/II trial in advanced EGFR-mutant non-small cell lung cancer
Poels, Kamrine E, Schoenfeld, Adam J, Makhnin, Alex, Tobi, Yosef, Wang, Yuli, Frisco-Cabanos, Heidie, Chakrabarti, Shaon, Shi, Manli, Napoli, Chelsi, McDonald, Thomas O, Tan, Weiwei, Hata, Aaron, Weinrich, Scott L, Yu, Helena A, Michor, Franziska
Published in Nature communications (17.06.2021)
Published in Nature communications (17.06.2021)
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Author Correction: Identification of optimal dosing schedules of dacomitinib and osimertinib for a phase I/II trial in advanced EGFR-mutant non-small cell lung cancer
Poels, Kamrine E, Schoenfeld, Adam J, Makhnin, Alex, Tobi, Yosef, Wang, Yuli, Frisco-Cabanos, Heidie, Chakrabarti, Shaon, Shi, Manli, Napoli, Chelsi, McDonald, Thomas O, Tan, Weiwei, Hata, Aaron, Weinrich, Scott L, Yu, Helena A, Michor, Franziska
Published in Nature communications (23.09.2022)
Published in Nature communications (23.09.2022)
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Evolutionary Action Score of TP53 Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients
Osman, Abdullah A, Neskey, David M, Katsonis, Panagiotis, Patel, Ameeta A, Ward, Alexandra M, Hsu, Teng-Kuei, Hicks, Stephanie C, McDonald, Thomas O, Ow, Thomas J, Alves, Marcus Ortega, Pickering, Curtis R, Skinner, Heath D, Zhao, Mei, Sturgis, Eric M, Kies, Merrill S, El-Naggar, Adel, Perrone, Federica, Licitra, Lisa, Bossi, Paolo, Kimmel, Marek, Frederick, Mitchell J, Lichtarge, Olivier, Myers, Jeffrey N
Published in Cancer research (Chicago, Ill.) (01.04.2015)
Published in Cancer research (Chicago, Ill.) (01.04.2015)
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The Myeloperoxidase Product Hypochlorous Acid Oxidizes HDL in the Human Artery Wall and Impairs ABCA1-Dependent Cholesterol Transport
Bergt, Constanze, Pennathur, Subramaniam, Fu, Xiaoyun, Byun, Jaeman, O'Brien, Kevin, McDonald, Thomas O., Singh, Pragya, Anantharamaiah, G. M., Chait, Alan, Brunzell, John, Geary, Randolph L., Oram, John F., Heinecke, Jay W., Klebanoff, Seymour J.
Published in Proceedings of the National Academy of Sciences - PNAS (31.08.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (31.08.2004)
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The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques
van Gils, Janine M, Derby, Merran C, Fernandes, Luciana R, Ramkhelawon, Bhama, Ray, Tathagat D, Rayner, Katey J, Parathath, Sajesh, Distel, Emilie, Feig, Jessica L, Alvarez-Leite, Jacqueline I, Rayner, Alistair J, McDonald, Thomas O, O'Brien, Kevin D, Stuart, Lynda M, Fisher, Edward A, Lacy-Hulbert, Adam, Moore, Kathryn J
Published in Nature immunology (01.02.2012)
Published in Nature immunology (01.02.2012)
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Human Atherosclerotic Intima and Blood of Patients with Established Coronary Artery Disease Contain High Density Lipoprotein Damaged by Reactive Nitrogen Species
Pennathur, Subramaniam, Bergt, Constanze, Shao, Baohai, Byun, Jaeman, Kassim, Sean Y, Singh, Pragya, Green, Pattie S, McDonald, Thomas O, Brunzell, John, Chait, Alan, Oram, John F, O'brien, Kevin, Geary, Randolph L, Heinecke, Jay W
Published in The Journal of biological chemistry (08.10.2004)
Published in The Journal of biological chemistry (08.10.2004)
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Serum amyloid A3 does not contribute to circulating SAA levels
Chiba, Tsuyoshi, Han, Chang Yeop, Vaisar, Tomas, Shimokado, Kentaro, Kargi, Atil, Chen, Mei-Hsiu, Wang, Shari, McDonald, Thomas O., O'Brien, Kevin D., Heinecke, Jay W, Chait, Alan
Published in Journal of lipid research (01.07.2009)
Published in Journal of lipid research (01.07.2009)
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Acrolein Impairs ATP Binding Cassette Transporter A1-dependent Cholesterol Export from Cells through Site-specific Modification of Apolipoprotein A-I
Shao, Baohai, Fu, Xiaoyun, McDonald, Thomas O., Green, Pattie S., Uchida, Koji, O'Brien, Kevin D., Oram, John F., Heinecke, Jay W.
Published in The Journal of biological chemistry (28.10.2005)
Published in The Journal of biological chemistry (28.10.2005)
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Mice Lacking Hepatic Lipase Are Lean and Protected against Diet-Induced Obesity and Hepatic Steatosis
Chiu, Harvey K, Qian, Kun, Ogimoto, Kayoko, Morton, Gregory J, Wisse, Brent E, Agrawal, Nalini, McDonald, Thomas O, Schwartz, Michael W, Dichek, Helén L
Published in Endocrinology (Philadelphia) (01.03.2010)
Published in Endocrinology (Philadelphia) (01.03.2010)
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Breast tumours maintain a reservoir of subclonal diversity during expansion
Minussi, Darlan C, Nicholson, Michael D, Ye, Hanghui, Davis, Alexander, Wang, Kaile, Baker, Toby, Tarabichi, Maxime, Sei, Emi, Du, Haowei, Rabbani, Mashiat, Peng, Cheng, Hu, Min, Bai, Shanshan, Lin, Yu-Wei, Schalck, Aislyn, Multani, Asha, Ma, Jin, McDonald, Thomas O, Casasent, Anna, Barrera, Angelica, Chen, Hui, Lim, Bora, Arun, Banu, Meric-Bernstam, Funda, Van Loo, Peter, Michor, Franziska, Navin, Nicholas E
Published in Nature (London) (08.04.2021)
Published in Nature (London) (08.04.2021)
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Serum Amyloid A and Lipoprotein Retention in Murine Models of Atherosclerosis
O’Brien, Kevin D, McDonald, Thomas O, Kunjathoor, Vidya, Eng, KimLi, Knopp, Eleanor A, Lewis, Katherine, Lopez, Roland, Kirk, Elizabeth A, Chait, Alan, Wight, Thomas N, deBeer, Frederick C, LeBoeuf, Renee C
Published in Arteriosclerosis, thrombosis, and vascular biology (01.04.2005)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.04.2005)
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