PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery
Ramracheya, Reshma D., McCulloch, Laura J., Clark, Anne, Wiggins, David, Johannessen, Helene, Olsen, Magnus Kringstad, Cai, Xing, Zhao, Chun-Mei, Chen, Duan, Rorsman, Patrik
Published in Cell reports (Cambridge) (03.05.2016)
Published in Cell reports (Cambridge) (03.05.2016)
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Journal Article
GLP-1 analogue-induced weight loss does not improve obesity-induced AT dysfunction
Pastel, Emilie, McCulloch, Laura J, Ward, Rebecca, Joshi, Shivam, Gooding, Kim M, Shore, Angela C, Kos, Katarina
Published in Clinical science (1979) (01.03.2017)
Published in Clinical science (1979) (01.03.2017)
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COL6A3 Is Regulated by Leptin in Human Adipose Tissue and Reduced in Obesity
McCulloch, Laura J, Rawling, Tom J, Sjöholm, Kajsa, Franck, Niclas, Dankel, Simon N, Price, Emily J, Knight, Bridget, Liversedge, Neil H, Mellgren, Gunnar, Nystrom, Fredrik, Carlsson, Lena M, Kos, Katarina
Published in Endocrinology (Philadelphia) (01.01.2015)
Published in Endocrinology (Philadelphia) (01.01.2015)
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Much ado about norming: the Behavior Rating Inventory of Executive Function
Roth, Robert M, Erdodi, Laszlo A, McCulloch, Laura J, Isquith, Peter K
Published in Child neuropsychology (04.03.2015)
Published in Child neuropsychology (04.03.2015)
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Journal Article
A role for SPARC in the moderation of human insulin secretion
Harries, Lorna W, McCulloch, Laura J, Holley, Janet E, Rawling, Thomas J, Welters, Hannah J, Kos, Katarina
Published in PloS one (28.06.2013)
Published in PloS one (28.06.2013)
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Systematic review of social media interventions for smoking cessation
Naslund, John A, Kim, Sunny Jung, Aschbrenner, Kelly A, McCulloch, Laura J, Brunette, Mary F, Dallery, Jesse, Bartels, Stephen J, Marsch, Lisa A
Published in Addictive behaviors (01.10.2017)
Published in Addictive behaviors (01.10.2017)
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GLUT2 (SLC2A2) is not the principal glucose transporter in human pancreatic beta cells: Implications for understanding genetic association signals at this locus
McCulloch, Laura J., van de Bunt, Martijn, Braun, Matthias, Frayn, Keith N., Clark, Anne, Gloyn, Anna L.
Published in Molecular genetics and metabolism (01.12.2011)
Published in Molecular genetics and metabolism (01.12.2011)
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Journal Article
The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver
Beer, Nicola L., Tribble, Nicholas D., McCulloch, Laura J., Roos, Charlotta, Johnson, Paul R.V., Orho-Melander, Marju, Gloyn, Anna L.
Published in Human molecular genetics (01.11.2009)
Published in Human molecular genetics (01.11.2009)
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An in-frame deletion at the polymerase active site of POLD1 causes a multisystem disorder with lipodystrophy
Weedon, Michael N, Ellard, Sian, Prindle, Marc J, Caswell, Richard, Allen, Hana Lango, Oram, Richard, Godbole, Koumudi, Yajnik, Chittaranjan S, Sbraccia, Paolo, Novelli, Giuseppe, Turnpenny, Peter, McCann, Emma, Goh, Kim Jee, Wang, Yukai, Fulford, Jonathan, McCulloch, Laura J, Savage, David B, O'Rahilly, Stephen, Kos, Katarina, Loeb, Lawrence A, Semple, Robert K, Hattersley, Andrew T
Published in Nature genetics (01.08.2013)
Published in Nature genetics (01.08.2013)
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Journal Article
Sitagliptin and Roux‐en‐Y gastric bypass modulate insulin secretion via regulation of intra‐islet PYY
Guida, Claudia, McCulloch, Laura J., Godazgar, Mahdieh, Stephen, Sam D., Baker, Charlotte, Basco, Davide, Dong, Jiawen, Chen, Duan, Clark, Anne, Ramracheya, Reshma D
Published in Diabetes, obesity & metabolism (01.03.2018)
Published in Diabetes, obesity & metabolism (01.03.2018)
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Journal Article
A genome-wide association search for type 2 diabetes genes in African Americans
Palmer, Nicholette D, McDonough, Caitrin W, Hicks, Pamela J, Roh, Bong H, Wing, Maria R, An, S Sandy, Hester, Jessica M, Cooke, Jessica N, Bostrom, Meredith A, Rudock, Megan E, Talbert, Matthew E, Lewis, Joshua P, Ferrara, Assiamira, Lu, Lingyi, Ziegler, Julie T, Sale, Michele M, Divers, Jasmin, Shriner, Daniel, Adeyemo, Adebowale, Rotimi, Charles N, Ng, Maggie C Y, Langefeld, Carl D, Freedman, Barry I, Bowden, Donald W, Voight, Benjamin F, Scott, Laura J, Steinthorsdottir, Valgerdur, Morris, Andrew P, Dina, Christian, Welch, Ryan P, Zeggini, Eleftheria, Huth, Cornelia, Aulchenko, Yurii S, Thorleifsson, Gudmar, McCulloch, Laura J, Ferreira, Teresa, Grallert, Harald, Amin, Najaf, Wu, Guanming, Willer, Cristen J, Raychaudhuri, Soumya, McCarroll, Steve A, Langenberg, Claudia, Hofmann, Oliver M, Dupuis, Josée, Qi, Lu, Segrè, Ayellet V, van Hoek, Mandy, Navarro, Pau, Ardlie, Kristin, Balkau, Beverley, Benediktsson, Rafn, Bennett, Amanda J, Blagieva, Roza, Boerwinkle, Eric, Bonnycastle, Lori L, Boström, Kristina Bengtsson, Bravenboer, Bert, Bumpstead, Suzannah, Burtt, Noël P, Charpentier, Guillaume, Chines, Peter S, Cornelis, Marilyn, Couper, David J, Crawford, Gabe, Doney, Alex S F, Elliott, Katherine S, Elliott, Amanda L, Erdos, Michael R, Fox, Caroline S, Franklin, Christopher S, Ganser, Martha, Gieger, Christian, Grarup, Niels, Green, Todd, Griffin, Simon, Groves, Christopher J, Guiducci, Candace, Hadjadj, Samy, Hassanali, Neelam, Herder, Christian, Isomaa, Bo, Jackson, Anne U, Johnson, Paul R V, Jørgensen, Torben, Kao, Wen H L, Klopp, Norman, Kong, Augustine, Kraft, Peter, Kuusisto, Johanna, Lauritzen, Torsten, Li, Man, Lieverse, Aloysius, Lindgren, Cecilia M, Lyssenko, Valeriya, Marre, Michel, Meitinger, Thomas, Midthjell, Kristian, Morken, Mario A, Narisu, Narisu
Published in PloS one (04.01.2012)
Published in PloS one (04.01.2012)
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Journal Article
Lysyl oxidase and adipose tissue dysfunction
Pastel, Emilie, Price, Emily, Sjöholm, Kajsa, McCulloch, Laura J., Rittig, Nikolaj, Liversedge, Neil, Knight, Bridget, Møller, Niels, Svensson, Per-Arne, Kos, Katarina
Published in Metabolism, clinical and experimental (01.01.2018)
Published in Metabolism, clinical and experimental (01.01.2018)
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Journal Article
Functional characterisation of ADIPOQ variants using individuals recruited by genotype
Lee, Benjamin P., Lloyd-Laney, Henry O., Locke, Jonathan M., McCulloch, Laura J., Knight, Bridget, Yaghootkar, Hanieh, Cory, Giles, Kos, Katarina, Frayling, Timothy M., Harries, Lorna W.
Published in Molecular and cellular endocrinology (15.06.2016)
Published in Molecular and cellular endocrinology (15.06.2016)
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Journal Article
Severe Insulin Resistance and Intrauterine Growth Deficiency Associated With Haploinsufficiency for INSR and CHN2: New Insights Into Synergistic Pathways Involved in Growth and Metabolism
SULIMAN, Sara G. I, STANIK, Juraj, ELLARD, Sian, VOLPI, Emanuela V, KLIMES, Iwar, GLOYN, Anna L, MCCULLOCH, Laura J, WILSON, Natalie, EDGHILL, Emma L, MISOVICOVA, Nadezda, GASPERIKOVA, Daniela, SANDRIKOVA, Vilja, ELLIOTT, Katherine S, BARAK, Lubomir
Published in Diabetes (New York, N.Y.) (01.12.2009)
Published in Diabetes (New York, N.Y.) (01.12.2009)
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Journal Article
Severe Insulin Resistance and Intrauterine Growth Deficiency Associated With Haploinsufficiency for INSR and CHN2
Suliman, Sara G.I., Stanik, Juraj, McCulloch, Laura J., Wilson, Natalie, Edghill, Emma L., Misovicova, Nadezda, Gasperikova, Daniela, Sandrikova, Vilja, Elliott, Katherine S., Barak, Lubomir, Ellard, Sian, Volpi, Emanuela V., Klimes, Iwar, Gloyn, Anna L.
Published in Diabetes (New York, N.Y.) (01.12.2009)
Published in Diabetes (New York, N.Y.) (01.12.2009)
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Journal Article
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
Dupuis, Josée, Saxena, Richa, Soranzo, Nicole, Wheeler, Eleanor, Bouatia-Naji, Nabila, Morris, Andrew P, Elliott, Paul, Rybin, Denis, Thorleifsson, Gudmar, Steinthorsdottir, Valgerdur, Dehghan, Abbas, Franklin, Christopher S, Song, Kijoung, Egan, Josephine M, Doney, Alex, Voight, Benjamin F, Stringham, Heather M, Qi, Lu, Gieger, Christian, Rocheleau, Ghislain, Payne, Felicity, Roccasecca, Rosa Maria, Sethupathy, Praveen, Balkau, Beverley, Barter, Philip, Benediktsson, Rafn, Bonnefond, Amélie, Charpentier, Guillaume, Chines, Peter, Cornelis, Marilyn, Day, Ian N M, de Geus, Eco J C, Erdos, Michael R, Graessler, Jürgen, Grundy, Scott, Hartikainen, Anna-Liisa, Hayward, Caroline, Heath, Simon C, Herder, Christian, Hicks, Andrew A, Hingorani, Aroon D, Hui, Jennie, Johnson, Paul R V, Kaakinen, Marika, Kaprio, Jaakko, Kesaniemi, Y Antero, Kivimaki, Mika, Knight, Beatrice, Li, Yun, Mahley, Robert, Mangino, Massimo, McAteer, Jarred B, McPherson, Ruth, Morken, Mario A, Narisu, Narisu, Pattaro, Cristian, Peden, John F, Pedersen, Nancy L, Polasek, Ozren, Posthuma, Danielle, Province, Michael A, Rayner, Nigel W, Roden, Michael, Sandbaek, Annelli, Sanna, Serena, Sayer, Avan Aihie, Scheet, Paul, Seedorf, Udo, Shields, Beverley, Silveira, Angela, Simpson, Laila, Swift, Amy, Syvänen, Ann-Christine, Thorand, Barbara, Tichet, Jean, Varma, Dhiraj, Waeber, Gérard, Walley, Andrew, Walters, G Bragi, Wild, Sarah H, Zeggini, Eleftheria, Zelenika, Diana, Zhai, Guangju, Zillikens, M Carola, Loos, Ruth J F, Meneton, Pierre, Williams, Gordon H, Silander, Kaisa, Schwarz, Peter, Karpe, Fredrik, Cooper, Cyrus, Serrano-Ríos, Manuel, Kuusisto, Johanna, Laakso, Markku, Hansen, Torben, Pramstaller, Peter Paul, Wichmann, H Erich, Illig, Thomas, Stumvoll, Michael, Wilson, James F
Published in Nature genetics (01.02.2010)
Published in Nature genetics (01.02.2010)
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Leveraging Cross-Species Transcription Factor Binding Site Patterns: From Diabetes Risk Loci to Disease Mechanisms
Dankel, Simon N., Klocke, Bernward, Grallert, Harald, Glunk, Viktoria, Lee, Heekyoung, Ehlers, Kerstin, Wahl, Simone, Hoffmann, Christoph, Qian, Kun, Riess, Helene, Schroeder, Timm, Horsthemke, Bernhard, Voight, Benjamin F., Welch, Ryan P., Zeggini, Eleftheria, Huth, Cornelia, Aulchenko, Yurii S., McCulloch, Laura J., Ferreira, Teresa, Amin, Najaf, McCarroll, Steve A., Qi, Lu, Navarro, Pau, Ardlie, Kristin, Benediktsson, Rafn, Bennett, Amanda J., Boström, Kristina Bengtsson, Burtt, Noël P., Charpentier, Guillaume, Crawford, Gabe, Erdos, Michael R., Fox, Caroline S., Franklin, Christopher S., Gieger, Christian, Grarup, Niels, Griffin, Simon, Groves, Christopher J., Hadjadj, Samy, Johnson, Paul R.V., Klopp, Norman, Kong, Augustine, Kraft, Peter, Lauritzen, Torsten, Li, Man, Lyssenko, Valeriya, Marre, Michel, Morken, Mario A., Narisu, Narisu, Nilsson, Peter, Owen, Katharine R., Payne, Felicity, Perry, John R.B., Petersen, Ann-Kristin, Shields, Beverley M., Shrader, Peter, Sigurdsson, Gunnar, Strassburger, Klaus, Stringham, Heather M., Sun, Qi, Tichet, Jean, van Dam, Rob M., van Haeften, Timon W., van Herpt, Thijs, van Vliet-Ostaptchouk, Jana V., Weedon, Michael N., Wijmenga, Cisca, Bergman, Richard N., Cauchi, Stephane, Collins, Francis S., Gyllensten, Ulf, Hansen, Torben, Hitman, Graham A., Hofman, Albert, Laakso, Markku, Rudan, Igor, Stein, Lincoln D., Tuomilehto, Jaakko, Uitterlinden, Andre, Walker, Mark, Wareham, Nicholas J., Daly, Mark J., Hu, Frank B., Pankow, James S., Pedersen, Oluf, Florez, Jose C., Frayling, Timothy M., Groop, Leif, Wilson, James F., Illig, Thomas, van Duijn, Cornelia M., Stefansson, Kari, Boehnke, Michael, Spieler, Derek, Klingenspor, Martin, Dahlman, Ingrid, Hauck, Stefanie M., Blüher, Matthias, Hsu, Yi-Hsiang, Mellgren, Gunnar, Hauner, Hans
Published in Cell (2014)
Published in Cell (2014)
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Journal Article
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
Voight, Benjamin F, Scott, Laura J, Morris, Andrew P, Dina, Christian, Welch, Ryan P, Zeggini, Eleftheria, Huth, Cornelia, Aulchenko, Yurii S, McCulloch, Laura J, Ferreira, Teresa, Grallert, Harald, Wu, Guanming, Raychaudhuri, Soumya, Langenberg, Claudia, Dupuis, Josée, Qi, Lu, Segrè, Ayellet V, van Hoek, Mandy, Navarro, Pau, Benediktsson, Rafn, Bonnycastle, Lori L, Charpentier, Guillaume, Cornelis, Marilyn, Couper, David J, Crawford, Gabe, Doney, Alex S F, Elliott, Amanda L, Erdos, Michael R, Grarup, Niels, Green, Todd, Groves, Christopher J, Guiducci, Candace, Hadjadj, Samy, Hassanali, Neelam, Isomaa, Bo, Johnson, Paul R V, Jørgensen, Torben, Kao, Wen H L, Klopp, Norman, Kong, Augustine, Kraft, Peter, Lauritzen, Torsten, Li, Man, Marre, Michel, Midthjell, Kristian, Morken, Mario A, Narisu, Narisu, Owen, Katharine R, Payne, Felicity, Perry, John R B, Petersen, Ann-Kristin, Platou, Carl, Proença, Christine, Prokopenko, Inga, Rathmann, Wolfgang, Rayner, N William, Rocheleau, Ghislain, Sampson, Michael J, Saxena, Richa, Shields, Beverley M, Shrader, Peter, Sigurdsson, Gunnar, Sparsø, Thomas, Stringham, Heather M, Sun, Qi, Swift, Amy J, Thorand, Barbara, Tichet, Jean, van Haeften, Timon W, van Herpt, Thijs, Walters, G Bragi, Weedon, Michael N, Wijmenga, Cisca, Witteman, Jacqueline, Bergman, Richard N, Cauchi, Stephane, Collins, Francis S, Gyllensten, Ulf, Hofman, Albert, Hunter, David J, Hveem, Kristian, Pramstaller, Peter P, Uitterlinden, Andre, Walker, Mark, Wareham, Nicholas J, Abecasis, Gonçalo R, Boehm, Bernhard O, Campbell, Harry, Daly, Mark J, Hu, Frank B, Meigs, James B, Pankow, James S, Pedersen, Oluf, Wichmann, H-Erich, Barroso, Inês, Florez, Jose C, Thorsteinsdottir, Unnur, Froguel, Philippe, van Duijn, Cornelia M, Stefansson, Kari
Published in Nature genetics (01.07.2010)
Published in Nature genetics (01.07.2010)
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