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Compuestos de 1-oxo-1,2-dihidroisoquinolin-7-il-(tiofen-2-il-5-sustituido)-sulfonamida, formulaciones que contienen esos compuestos, y su uso como inhibidores de AICARFT en el tratamiento de cánceres

Compuestos de 1-oxo-1,2-dihidroisoquinolin-7-il-(tiofen-2-il-5-sustituido)-sulfonamida, formulaciones que contienen esos compuestos, y su uso como inhibidores de AICARFT en el tratamiento de cánceres

by DURHAM, Timothy Barrett, TOTH, James Lee, MCCOWAN, Jefferson Ray, THRASHER, Kenneth Jeff, SI, Chong, FRIMPONG, Kwame, DALLY, Robert Dean, WU, Zhipei, SHEPHERD, Timothy Alan, FALES, Kevin Robert, NJOROGE, Frank George, BROOKS, Harold Burns
Year of Publication 28.06.2019

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1-OXO-1,2-DIHYDROISOQUINOLIN-7-YL-(5-SUBSTITUTED-THIOPHEN-2-YL)-SULFONAMIDE COMPOUNDS, FORMULATIONS CONTAINING THOSE COMPOUNDS, AND THEIR USE AS AICARFT INHIBITORS IN THE TREATMENT OF CANCERS

1-OXO-1,2-DIHYDROISOQUINOLIN-7-YL-(5-SUBSTITUTED-THIOPHEN-2-YL)-SULFONAMIDE COMPOUNDS, FORMULATIONS CONTAINING THOSE COMPOUNDS, AND THEIR USE AS AICARFT INHIBITORS IN THE TREATMENT OF CANCERS

by DURHAM, Timothy Barrett, TOTH, James Lee, MCCOWAN, Jefferson Ray, THRASHER, Kenneth Jeff, SI, Chong, FRIMPONG, Kwame, DALLY, Robert Dean, WU, Zhipei, SHEPHERD, Timothy Alan, FALES, Kevin Robert, NJOROGE, Frank George, BROOKS, Harold Burns
Year of Publication 13.02.2019

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1-OXO-1,2-DIHYDROISOQUINOLIN-7-YL-(5-SUBSTITUTED-THIOPHEN-2-YL)-SULFONAMIDE COMPOUNDS, FORMULATIONS CONTAINING THOSE COMPOUNDS, AND THEIR USE AS AICARFT INHIBITORS IN THE TREATMENT OF CANCERS

1-OXO-1,2-DIHYDROISOQUINOLIN-7-YL-(5-SUBSTITUTED-THIOPHEN-2-YL)-SULFONAMIDE COMPOUNDS, FORMULATIONS CONTAINING THOSE COMPOUNDS, AND THEIR USE AS AICARFT INHIBITORS IN THE TREATMENT OF CANCERS

by DURHAM, Timothy Barrett, TOTH, James Lee, MCCOWAN, Jefferson Ray, THRASHER, Kenneth Jeff, SI, Chong, FRIMPONG, Kwame, DALLY, Robert Dean, WU, Zhipei, SHEPHERD, Timothy Alan, FALES, Kevin Robert, NJOROGE, Frank George, BROOKS, Harold Burns
Year of Publication 11.10.2017

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1-oxo-1,2-dihydroisoquinolin-7-yl-(5-substituted-thiophen-2-yl)-sulfonamide compounds, formulations containing those compounds, and their use as AICARFT inhibitors in the treatment of cancers

1-oxo-1,2-dihydroisoquinolin-7-yl-(5-substituted-thiophen-2-yl)-sulfonamide compounds, formulations containing those compounds, and their use as AICARFT inhibitors in the treatment of cancers

by Brooks Harold Burns, Dally Robert Dean, Frimpong Kwame, Toth James Lee, Njoroge Frank George, Shepherd Timothy Alan, Si Chong, Fales Kevin Robert, McCowan Jefferson Ray, Wu Zhipei, Thrasher Kenneth Jeff, Durham Timothy Barrett
Year of Publication 03.10.2017

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1-OXO-1,2-DIHYDROISOQUINOLIN-7-YL-(5-SUBSTITUTED-THIOPHEN-2-YL)-SULFONAMIDE COMPOUNDS, FORMULATIONS CONTAINING THOSE COMPOUNDS, AND THEIR USE AS AICARFT INHIBITORS IN THE TREATMENT OF CANCERS

1-OXO-1,2-DIHYDROISOQUINOLIN-7-YL-(5-SUBSTITUTED-THIOPHEN-2-YL)-SULFONAMIDE COMPOUNDS, FORMULATIONS CONTAINING THOSE COMPOUNDS, AND THEIR USE AS AICARFT INHIBITORS IN THE TREATMENT OF CANCERS

by DALLY Robert Dean, WU Zhipei, NJOROGE Frank George, TOTH James Lee, DURHAM Timothy Barrett, THRASHER Kenneth Jeff, FALES Kevin Robert, SI Chong, MCCOWAN Jefferson Ray, FRIMPONG Kwame, SHEPHERD Timothy Alan, BROOKS Harold Burns
Year of Publication 17.08.2017

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N-(2-arylethyl)-benzylamines as antagonists of the 5-ht6 receptor and pharmaceutical compositions containing them

N-(2-arylethyl)-benzylamines as antagonists of the 5-ht6 receptor and pharmaceutical compositions containing them

by GIETHLEN BRUNO, GILLIG JAMES RONALD, MCCOWAN JEFFERSON RAY, FISHER MATTHEW JOSEPH, COHEN MICHAEL PHILIP, CHEN ZHAOGEN, MILLER SHAWN CHRISTOPHER, SCHAUS JOHN MEHNERT
Year of Publication 28.01.2016

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N-(2-ARYLETHYL) BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR

N-(2-ARYLETHYL) BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR

by MILLER, SHAWN CHRISTOPHER, SCHAUS, JOHN MEHNERT, CHEN, ZHAOGEN, GIETHLEN, BRUNO, GILLIG, JAMES RONALD, MCCOWAN, JEFFERSON RAY, COHEN, MICHAEL PHILIP, FISHER, MATTHEW JOSEPH
Year of Publication 30.12.2015

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1 -OXO-1,2-DIHYDROISOQUINOLIN-7-YL-(5-SUBSTITUTED-THIOPHEN-2-YL)-SULFONAMIDE COMPOUNDS, FORMULATIONS CONTAINING THOSE COMPOUNDS, AND THEIR USE AS AICARFT INHIBITORS IN THE TREATMENT OF CANCERS

1 -OXO-1,2-DIHYDROISOQUINOLIN-7-YL-(5-SUBSTITUTED-THIOPHEN-2-YL)-SULFONAMIDE COMPOUNDS, FORMULATIONS CONTAINING THOSE COMPOUNDS, AND THEIR USE AS AICARFT INHIBITORS IN THE TREATMENT OF CANCERS

by SI, CHONG, DALLY, ROBERT DEAN, FRIMPONG, KWAME, NJOROGE, FRANK GEORGE, WU, ZHIPEI, BROOKS, HAROLD BURNS, MCCOWAN, JEFFERSON RAY, TOTH, JAMES LEE, THRASHER, KENNETH JEFF, DURHAM, TIMOTHY BARRETT, FALES, KEVIN ROBERT, SHEPHERD, TIMOTHY ALAN
Year of Publication 09.06.2016

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Patent

1 -OXO-1,2-DIHYDROISOQUINOLIN-7-YL-(5-SUBSTITUTED-THIOPHEN-2-YL)-SULFONAMIDE COMPOUNDS, FORMULATIONS CONTAINING THOSE COMPOUNDS, AND THEIR USE AS AICARFT INHIBITORS IN THE TREATMENT OF CANCERS

1 -OXO-1,2-DIHYDROISOQUINOLIN-7-YL-(5-SUBSTITUTED-THIOPHEN-2-YL)-SULFONAMIDE COMPOUNDS, FORMULATIONS CONTAINING THOSE COMPOUNDS, AND THEIR USE AS AICARFT INHIBITORS IN THE TREATMENT OF CANCERS

by SI, CHONG, DALLY, ROBERT DEAN, FRIMPONG, KWAME, NJOROGE, FRANK GEORGE, WU, ZHIPEI, BROOKS, HAROLD BURNS, MCCOWAN, JEFFERSON RAY, TOTH, JAMES LEE, THRASHER, KENNETH JEFF, DURHAM, TIMOTHY BARRETT, FALES, KEVIN ROBERT, SHEPHERD, TIMOTHY ALAN
Year of Publication 09.06.2016

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Patent

N-(2-arylethyl)benzylamines as antagonists of the 5-HT6 receptor

N-(2-arylethyl)benzylamines as antagonists of the 5-HT6 receptor

by GIETHLEN BRUNO, GILLIG JAMES RONALD, MCCOWAN JEFFERSON RAY, FISHER MATTHEW JOSEPH, COHEN MICHAEL PHILIP, CHEN ZHAOGEN, MILLER SHAWN CHRISTOPHER, SCHAUS JOHN MEHNERT
Year of Publication 25.10.2011

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Patent

N-(2-arylethyl)benzylamines as antagonists of the 5-HT6 receptor

N-(2-arylethyl)benzylamines as antagonists of the 5-HT6 receptor

by Chen, Zhaogen, Cohen, Michael Philip, Fisher, Matthew Joseph, Giethlen, Bruno, Gillig, James Ronald, McCowan, Jefferson Ray, Miller, Shawn Christopher, Schaus, John Mehnert
Year of Publication 25.10.2011

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Patent

N-(2-ARYLETHYL)BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR

N-(2-ARYLETHYL)BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR

by MILLER, SHAWN CHRISTOPHER, SCHAUS, JOHN MEHNERT, CHEN, ZHAOGEN, GIETHLEN, BRUNO, GILLIG, JAMES RONALD, MCCOWAN, JEFFERSON RAY, COHEN, MICHAEL PHILIP, FISHER, MATTHEW JOSEPH
Year of Publication 21.06.2011

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Ν-(2-ΑΡΥΛΑΙΘΥΛΟ)ΒΕΝΖΥΛΑΜΙΝΕΣ ΩΣ ΑΝΤΑΓΩΝΙΣΤΕΣ ΤΟΥ 5-ΗT6 ΥΠΟΔΟΧΕΑ

Ν-(2-ΑΡΥΛΑΙΘΥΛΟ)ΒΕΝΖΥΛΑΜΙΝΕΣ ΩΣ ΑΝΤΑΓΩΝΙΣΤΕΣ ΤΟΥ 5-ΗT6 ΥΠΟΔΟΧΕΑ

by GILLIG James Ronald, COHEN Michael Philip, CHEN Zhaogen, MCCOWAN Jefferson Ray, SCHAUS John Mehnert, GIETHLEN Bruno, MILLER Shawn Christopher, FISHER Matthew Joseph
Year of Publication 26.04.2017

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Patent

BIPHENYL AMIDE LACTAM DERIVATIVES AS INHIBITORS OF 11- BETA-HYDROXYSTEROID DEHYDROGENASE 1

BIPHENYL AMIDE LACTAM DERIVATIVES AS INHIBITORS OF 11- BETA-HYDROXYSTEROID DEHYDROGENASE 1

by HITE, GARY, ALAN, KRASUTSKY, ALEXEI, PAVLOVYCH, YORK, JEREMY, SCHULENBURG, CHEN, ZHAOGEN, SNYDER, NANCY, JUNE, WALLACE, OWEN, BRENDAN, TOTH, JAMES, LEE, WINNEROSKI, JUNIOR, LEONARD, LARRY, HINKLIN, RONALD, JAY, XU, YANPING, MCCOWAN, JEFFERSON, RAY, AICHER, THOMAS, DANIEL, SAEED, ASHRAF, LI, RENHUA
Year of Publication 28.08.2013

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Patent

BIPHENYL AMIDE LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1

BIPHENYL AMIDE LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1

by WALLACE, OWEN BRENDAN, CHEN, ZHAOGEN, SNYDER, NANCY JUNE, HITE, GARY ALAN, AICHER, THOMAS DANIEL, KRASUTSKY, ALEXEI PAVLOVYCH, WINNEROSKI, JUNIOR LEONARD LARRY, XU, YANPING, HINKLIN, RONALD JAY, SAEED, ASHRAF, MCCOWAN, JEFFERSON RAY, TOTH, JAMES LEE, LI, RENHUA, YORK, JEREMY SCHULENBURG
Year of Publication 27.08.2013

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Patent

N-(2-arylethyl) benzylamines as antagonists of 5-HT6 receptor

N-(2-arylethyl) benzylamines as antagonists of 5-HT6 receptor

by GIETHLEN BRUNO, GILLIG JAMES RONALD, MCCOWAN JEFFERSON RAY, FISHER MATTHEW JOSEPH, COHEN MICHAEL PHILIP, CHEN ZHAOGEN, MILLER SHAWN CHRISTOPHER, SCHAUS JOHN MEHNERT
Year of Publication 07.10.2010

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Biphenyl amide lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1

Biphenyl amide lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1

by Aicher, Thomas Daniel, Chen, Zhaogen, Hinklin, Ronald Jay, Hite, Gary Alan, Krasutsky, Alexei Pavlovych, Li, Renhua, McCowan, Jefferson Ray, Saeed, Ashraf, Snyder, Nancy June, Toth, James Lee, Wallace, Owen Brendan, Winneroski, Jr, Leonard Larry, Xu, Yanping, York, Jeremy Schulenburg
Year of Publication 03.01.2012

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N-(2-ARYLETHYL) BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR

N-(2-ARYLETHYL) BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR

by Giethlen Bruno, Chen Zhaogen, Gillig James Ronald, Schaus John Mehnert, Cohen Michael Philip, McCowan Jefferson Ray, Miller Shawn Christopher, Fisher Matthew Joseph
Year of Publication 29.07.2016

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Patent

1-oxo-1,2-dihydroisoquinolin-7-yl-(5-substituted-thiophen-2-yl)-sulfonamide compounds, formulations containing those compounds, and their use as aicarft inhibitors in the treatment of cancers

1-oxo-1,2-dihydroisoquinolin-7-yl-(5-substituted-thiophen-2-yl)-sulfonamide compounds, formulations containing those compounds, and their use as aicarft inhibitors in the treatment of cancers

by NJOROGE FRANK GEORGE, FRIMPONG KWAME, SI CHONG, TOTH JAMES LEE, BROOKS HAROLD BURNS, FALES KEVIN ROBERT, MCCOWAN JEFFERSON RAY, THRASHER KENNETH JEFF, SHEPHERD TIMOTHY ALAN, WU ZHIPEI, DALLY ROBERT DEAN, DURHAM TIMOTHY BARRETT
Year of Publication 01.08.2017

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Benzothiophenderivate als antithrombotische Mitteln und Zwischenprodukte

Benzothiophenderivate als antithrombotische Mitteln und Zwischenprodukte

by MCCOWAN, JEFFERSON RAY, TOTH, JOHN ELDON, SALL, DANIEL JON
Year of Publication 17.07.2003

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