Dysregulated transcriptional responses to SARS-CoV-2 in the periphery
McClain, Micah T., Constantine, Florica J., Henao, Ricardo, Liu, Yiling, Tsalik, Ephraim L., Burke, Thomas W., Steinbrink, Julie M., Petzold, Elizabeth, Nicholson, Bradly P., Rolfe, Robert, Kraft, Bryan D., Kelly, Matthew S., Saban, Daniel R., Yu, Chen, Shen, Xiling, Ko, Emily M., Sempowski, Gregory D., Denny, Thomas N., Ginsburg, Geoffrey S., Woods, Christopher W.
Published in Nature communications (17.02.2021)
Published in Nature communications (17.02.2021)
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Host gene expression classifiers diagnose acute respiratory illness etiology
Tsalik, Ephraim L, Henao, Ricardo, Nichols, Marshall, Burke, Thomas, Ko, Emily R, McClain, Micah T, Hudson, Lori L, Mazur, Anna, Freeman, Debra H, Veldman, Tim, Langley, Raymond J, Quackenbush, Eugenia B, Glickman, Seth W, Cairns, Charles B, Jaehne, Anja K, Rivers, Emanuel P, Otero, Ronny M, Zaas, Aimee K, Kingsmore, Stephen F, Lucas, Joseph, Fowler, Jr, Vance G, Carin, Lawrence, Ginsburg, Geoffrey S, Woods, Christopher W
Published in Science translational medicine (20.01.2016)
Published in Science translational medicine (20.01.2016)
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Deep Sequencing of Influenza A Virus from a Human Challenge Study Reveals a Selective Bottleneck and Only Limited Intrahost Genetic Diversification
Sobel Leonard, Ashley, McClain, Micah T, Smith, Gavin J D, Wentworth, David E, Halpin, Rebecca A, Lin, Xudong, Ransier, Amy, Stockwell, Timothy B, Das, Suman R, Gilbert, Anthony S, Lambkin-Williams, Robert, Ginsburg, Geoffrey S, Woods, Christopher W, Koelle, Katia
Published in Journal of virology (15.12.2016)
Published in Journal of virology (15.12.2016)
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Temporal dynamics of host molecular responses differentiate symptomatic and asymptomatic influenza a infection
Huang, Yongsheng, Zaas, Aimee K, Rao, Arvind, Dobigeon, Nicolas, Woolf, Peter J, Veldman, Timothy, Øien, N Christine, McClain, Micah T, Varkey, Jay B, Nicholson, Bradley, Carin, Lawrence, Kingsmore, Stephen, Woods, Christopher W, Ginsburg, Geoffrey S, Hero, 3rd, Alfred O
Published in PLoS genetics (01.08.2011)
Published in PLoS genetics (01.08.2011)
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Systematic comparison of published host gene expression signatures for bacterial/viral discrimination
Bodkin, Nicholas, Ross, Melissa, McClain, Micah T, Ko, Emily R, Woods, Christopher W, Ginsburg, Geoffrey S, Henao, Ricardo, Tsalik, Ephraim L
Published in Genome medicine (21.02.2022)
Published in Genome medicine (21.02.2022)
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Journal Article
A host transcriptional signature for presymptomatic detection of infection in humans exposed to influenza H1N1 or H3N2
Woods, Christopher W, McClain, Micah T, Chen, Minhua, Zaas, Aimee K, Nicholson, Bradly P, Varkey, Jay, Veldman, Timothy, Kingsmore, Stephen F, Huang, Yongsheng, Lambkin-Williams, Robert, Gilbert, Anthony G, Hero, 3rd, Alfred O, Ramsburg, Elizabeth, Glickman, Seth, Lucas, Joseph E, Carin, Lawrence, Ginsburg, Geoffrey S
Published in PloS one (09.01.2013)
Published in PloS one (09.01.2013)
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Transcriptional responses define dysregulated immune activation in Hepatitis C (HCV)-naïve recipients of HCV-infected donor kidneys
Steinbrink, Julie M, Miller, Cameron, Myers, Rachel A, Sanoff, Scott, Mazur, Anna, Burke, Thomas W, Byrns, Jennifer, Jackson, Annette M, Luo, Xunrong, McClain, Micah T
Published in PloS one (01.01.2023)
Published in PloS one (01.01.2023)
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A comparison of host response strategies to distinguish bacterial and viral infection
Ross, Melissa, Henao, Ricardo, Burke, Thomas W, Ko, Emily R, McClain, Micah T, Ginsburg, Geoffrey S, Woods, Christopher W, Tsalik, Ephraim L
Published in PloS one (14.12.2021)
Published in PloS one (14.12.2021)
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Journal Article
Development of Autoantibodies before the Clinical Onset of Systemic Lupus Erythematosus
Arbuckle, Melissa R, McClain, Micah T, Rubertone, Mark V, Scofield, R. Hal, Dennis, Gregory J, James, Judith A, Harley, John B
Published in The New England journal of medicine (16.10.2003)
Published in The New England journal of medicine (16.10.2003)
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An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility
Wang, Liuyang, Balmat, Thomas J, Antonia, Alejandro L, Constantine, Florica J, Henao, Ricardo, Burke, Thomas W, Ingham, Andy, McClain, Micah T, Tsalik, Ephraim L, Ko, Emily R, Ginsburg, Geoffrey S, DeLong, Mark R, Shen, Xiling, Woods, Christopher W, Hauser, Elizabeth R, Ko, Dennis C
Published in Genome medicine (17.05.2021)
Published in Genome medicine (17.05.2021)
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Journal Article
Host-response transcriptional biomarkers accurately discriminate bacterial and viral infections of global relevance
Ko, Emily R., Reller, Megan E., Tillekeratne, L. Gayani, Bodinayake, Champica K., Miller, Cameron, Burke, Thomas W., Henao, Ricardo, McClain, Micah T., Suchindran, Sunil, Nicholson, Bradly, Blatt, Adam, Petzold, Elizabeth, Tsalik, Ephraim L., Nagahawatte, Ajith, Devasiri, Vasantha, Rubach, Matthew P., Maro, Venance P., Lwezaula, Bingileki F., Kodikara-Arachichi, Wasantha, Kurukulasooriya, Ruvini, De Silva, Aruna D., Clark, Danielle V., Schully, Kevin L., Madut, Deng, Dumler, J. Stephen, Kato, Cecilia, Galloway, Renee, Crump, John A., Ginsburg, Geoffrey S., Minogue, Timothy D., Woods, Christopher W.
Published in Scientific reports (18.12.2023)
Published in Scientific reports (18.12.2023)
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Journal Article
Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion
Giroux, Nicholas S., Ding, Shengli, McClain, Micah T., Burke, Thomas W., Petzold, Elizabeth, Chung, Hong A., Rivera, Grecia O., Wang, Ergang, Xi, Rui, Bose, Shree, Rotstein, Tomer, Nicholson, Bradly P., Chen, Tianyi, Henao, Ricardo, Sempowski, Gregory D., Denny, Thomas N., De Ussel, Maria Iglesias, Satterwhite, Lisa L., Ko, Emily R., Ginsburg, Geoffrey S., Kraft, Bryan D., Tsalik, Ephraim L., Shen, Xiling, Woods, Christopher W.
Published in Scientific reports (09.07.2022)
Published in Scientific reports (09.07.2022)
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Journal Article
Host response to influenza infections in human blood: association of influenza severity with host genetics and transcriptomic response
Schughart, Klaus, Smith, Amber M, Tsalik, Ephraim L, Threlkeld, Stephen C, Sellers, Subhashini, Fischer, 2nd, William A, Schreiber, Jens, Lücke, Eva, Cornberg, Markus, Debarry, Jennifer, Woods, Christopher W, McClain, Micah T, Heise, Mark
Published in Frontiers in immunology (13.08.2024)
Published in Frontiers in immunology (13.08.2024)
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Journal Article
Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry
James, Judith A, McClain, Micah T, Heinlen, Latisha D, Dennis, Gregory J, Roebuck, Jon, Harley, John B
Published in Nature medicine (01.01.2005)
Published in Nature medicine (01.01.2005)
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Journal Article
The Host Response to Viral Infections Reveals Common and Virus-Specific Signatures in the Peripheral Blood
Tsalik, Ephraim L, Fiorino, Cassandra, Aqeel, Ammara, Liu, Yiling, Henao, Ricardo, Ko, Emily R, Burke, Thomas W, Reller, Megan E, Bodinayake, Champica K, Nagahawatte, Ajith, Arachchi, Wasantha K, Devasiri, Vasantha, Kurukulasooriya, Ruvini, McClain, Micah T, Woods, Christopher W, Ginsburg, Geoffrey S, Tillekeratne, L Gayani, Schughart, Klaus
Published in Frontiers in immunology (27.10.2021)
Published in Frontiers in immunology (27.10.2021)
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Journal Article
Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
Garrido, Carolina, Hurst, Jillian H, Lorang, Cynthia G, Aquino, Jhoanna N, Rodriguez, Javier, Pfeiffer, Trevor S, Singh, Tulika, Semmes, Eleanor C, Lugo, Debra J, Rotta, Alexandre T, Turner, Nicholas A, Burke, Thomas W, McClain, Micah T, Petzold, Elizabeth A, Permar, Sallie R, Moody, M Anthony, Woods, Christopher W, Kelly, Matthew S, Fouda, Genevieve G
Published in JCI insight (08.09.2021)
Published in JCI insight (08.09.2021)
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Journal Article
Author Correction: Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion
Giroux, Nicholas S., Ding, Shengli, McClain, Micah T., Burke, Thomas W., Petzold, Elizabeth, Chung, Hong A., Rivera, Grecia O., Wang, Ergang, Xi, Rui, Bose, Shree, Rotstein, Tomer, Nicholson, Bradly P., Chen, Tianyi, Henao, Ricardo, Sempowski, Gregory D., Denny, Thomas N., De Ussel, Maria Iglesias, Satterwhite, Lisa L., Ko, Emily R., Ginsburg, Geoffrey S., Kraft, Bryan D., Tsalik, Ephraim L., Shen, Xiling, Woods, Christopher W.
Published in Scientific reports (20.04.2023)
Published in Scientific reports (20.04.2023)
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Journal Article
A host gene expression approach for identifying triggers of asthma exacerbations
Lydon, Emily C, Bullard, Charles, Aydin, Mert, Better, Olga M, Mazur, Anna, Nicholson, Bradly P, Ko, Emily R, McClain, Micah T, Ginsburg, Geoffrey S, Woods, Chris W, Burke, Thomas W, Henao, Ricardo, Tsalik, Ephraim L
Published in PloS one (08.04.2019)
Published in PloS one (08.04.2019)
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Journal Article
The host transcriptional response to Candidemia is dominated by neutrophil activation and heme biosynthesis and supports novel diagnostic approaches
Steinbrink, Julie M, Myers, Rachel A, Hua, Kaiyuan, Johnson, Melissa D, Seidelman, Jessica L, Tsalik, Ephraim L, Henao, Ricardo, Ginsburg, Geoffrey S, Woods, Christopher W, Alexander, Barbara D, McClain, Micah T
Published in Genome medicine (05.07.2021)
Published in Genome medicine (05.07.2021)
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Journal Article
A response adaptive randomization platform trial for efficient evaluation of Ebola virus treatments: A model for pandemic response
Berry, Scott M, Petzold, Elizabeth A, Dull, Peter, Thielman, Nathan M, Cunningham, Coleen K, Corey, G Ralph, McClain, Micah T, Hoover, David L, Russell, James, Griffiss, J McLeod, Woods, Christopher W
Published in Clinical trials (London, England) (01.02.2016)
Published in Clinical trials (London, England) (01.02.2016)
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