Search Results - "MCCARRICK MARGARET" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Design and Synthesis of Novel and Selective Phosphodiesterase 2 (PDE2a) Inhibitors for the Treatment of Memory Disorders

Design and Synthesis of Novel and Selective Phosphodiesterase 2 (PDE2a) Inhibitors for the Treatment of Memory Disorders

by Gomez, Laurent, Massari, Mark Eben, Vickers, Troy, Freestone, Graeme, Vernier, William, Ly, Kiev, Xu, Rui, McCarrick, Margaret, Marrone, Tami, Metz, Markus, Yan, Yingzhou G, Yoder, Zachary W, Lemus, Robert, Broadbent, Nicola J, Barido, Richard, Warren, Noelle, Schmelzer, Kara, Neul, David, Lee, Dong, Andersen, Carsten B, Sebring, Kristen, Aertgeerts, Kathleen, Zhou, Xianbo, Tabatabaei, Ali, Peters, Marco, Breitenbucher, J. Guy
Published in Journal of medicinal chemistry (09.03.2017)

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Journal Article

Discovery and optimization of thieno[2,3-d]pyrimidines as B-Raf inhibitors

Discovery and optimization of thieno[2,3-d]pyrimidines as B-Raf inhibitors

by Packard, Garrick K., Papa, Patrick, Riggs, Jennifer R., Erdman, Paul, Tehrani, Lida, Robinson, Dale, Harris, Roy, Shevlin, Graziella, Perrin-Ninkovic, Sophie, Hilgraf, Robert, McCarrick, Margaret A., Tran, Tam, Fleming, Yuedi, Bai, April, Richardson, Samantha, Katz, Jason, Tang, Yang, Leisten, Jim, Moghaddam, Mehran, Cathers, Brian, Zhu, Dan, Sakata, Steven
Published in Bioorganic & medicinal chemistry letters (01.01.2012)

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A model of the acid sphingomyelinase phosphoesterase domain based on its remote structural homolog purple acid phosphatase

A model of the acid sphingomyelinase phosphoesterase domain based on its remote structural homolog purple acid phosphatase

by Seto, Marian, Whitlow, Marc, McCarrick, Margaret A., Srinivasan, Subha, Zhu, Ying, Pagila, Rene, Mintzer, Robert, Light, David, Johns, Anthony, Meurer‐Ogden, Janet A.
Published in Protein science (01.12.2004)

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Hetero-Diels-Alder reaction transition structures: reactivity, stereoselectivity, catalysis, solvent effects, and the exo-lone-pair effect

Hetero-Diels-Alder reaction transition structures: reactivity, stereoselectivity, catalysis, solvent effects, and the exo-lone-pair effect

by McCarrick, Margaret A, Wu, Yun Dong, Houk, K. N
Published in Journal of organic chemistry (01.06.1993)

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Structure Function Differences in Nonpeptide CCR1 Antagonists for Human and Mouse CCR1

Structure Function Differences in Nonpeptide CCR1 Antagonists for Human and Mouse CCR1

by Onuffer, James, McCarrick, Margaret A, Dunning, Laura, Liang, Meina, Rosser, Mary, Wei, Guo-Ping, Ng, Howard, Horuk, Richard
Published in The Journal of immunology (1950) (15.02.2003)

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Synthesis, Characterization, and Structure−Activity Relationships of Amidine-Substituted (Bis)benzylidene-Cycloketone Olefin Isomers as Potent and Selective Factor Xa Inhibitors

Synthesis, Characterization, and Structure−Activity Relationships of Amidine-Substituted (Bis)benzylidene-Cycloketone Olefin Isomers as Potent and Selective Factor Xa Inhibitors

by Guilford, William J, Shaw, Kenneth J, Dallas, Jerry L, Koovakkat, Sunil, Lee, Wheeseong, Liang, Amy, Light, David R, McCarrick, Margaret A, Whitlow, Marc, Ye, Bin, Morrissey, Michael M
Published in Journal of medicinal chemistry (30.12.1999)

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Human Factor Xa Bound Amidine Inhibitor Conformation by Double Rotational-Echo Double Resonance Nuclear Magnetic Resonance and Molecular Dynamics Simulations

Human Factor Xa Bound Amidine Inhibitor Conformation by Double Rotational-Echo Double Resonance Nuclear Magnetic Resonance and Molecular Dynamics Simulations

by McDowell, Lynda M, McCarrick, Margaret A, Studelska, Daniel R, O'Connor, Robert D, Light, David R, Guilford, William J, Arnaiz, Damian, Adler, Marc, Dallas, Jerry L, Poliks, Barbara, Schaefer, Jacob
Published in Journal of medicinal chemistry (30.01.2003)

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Predicting relative binding affinities of non-peptide HIV protease inhibitors with free energy perturbation calculations

Predicting relative binding affinities of non-peptide HIV protease inhibitors with free energy perturbation calculations

by McCarrick, M A, Kollman, P A
Published in Journal of computer-aided molecular design (01.03.1999)

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exo-Lone-pair effect on hetero-Diels-Alder cycloaddition stereochemistry

exo-Lone-pair effect on hetero-Diels-Alder cycloaddition stereochemistry

by McCarrick, Margaret A, Wu, Yun Dong, Houk, K. N
Published in Journal of the American Chemical Society (01.02.1992)

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Journal Article

Transition structures for hydrogen atom transfers to oxygen. Comparisons of intermolecular and intramolecular processes, and open- and closed-shell systems

Transition structures for hydrogen atom transfers to oxygen. Comparisons of intermolecular and intramolecular processes, and open- and closed-shell systems

by Dorigo, Andrea E, McCarrick, Margaret A, Loncharich, Richard J, Houk, K. N
Published in Journal of the American Chemical Society (01.10.1990)

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Journal Article

Conformations of Trypsin-Bound Amidine Inhibitors of Blood Coagulant Factor Xa by Double REDOR NMR and MD Simulations

Conformations of Trypsin-Bound Amidine Inhibitors of Blood Coagulant Factor Xa by Double REDOR NMR and MD Simulations

by McDowell, Lynda M, McCarrick, Margaret A, Studelska, Daniel R, Guilford, William J, Arnaiz, Damian, Dallas, Jerry L, Light, David R, Whitlow, Marc, Schaefer, Jacob
Published in Journal of medicinal chemistry (23.09.1999)

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Journal Article

(Z,Z)-2,7-Bis(4-amidinobenzylidene)cycloheptan-1-one: Identification of a Highly Active Inhibitor of Blood Coagulation Factor Xa

(Z,Z)-2,7-Bis(4-amidinobenzylidene)cycloheptan-1-one: Identification of a Highly Active Inhibitor of Blood Coagulation Factor Xa

by Shaw, Kenneth J, Guilford, William J, Dallas, Jerry L, Koovakkaat, Sunil K, McCarrick, Margaret A, Liang, Amy, Light, David R, Morrissey, Michael M
Published in Journal of medicinal chemistry (10.09.1998)

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Journal Article

PDE1 억제제로서의 치환된 푸라노피리미딘 화합물

PDE1 억제제로서의 치환된 푸라노피리미딘 화합물

by CHUNG DEMICHAEL, BURNS AARON, TRAN JOE, DYCK BRIAN, KLEINKE ANDREW, RAFFAELE NICHOLAS, WEINHOUSE MICHAEL, KUMAR DANGE VIJAY, BOOKSER BRETT, BOTROUS IRINY, MCCARRICK MARGARET
Year of Publication 18.09.2020

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Patent

Transition structures for hydrogen atom transfers to oxygen. Comparisons of intermolecular and intramolecular processes, and open- and closed-shell systems [Erratum to document cited in CA113(19):171436c]

Transition structures for hydrogen atom transfers to oxygen. Comparisons of intermolecular and intramolecular processes, and open- and closed-shell systems [Erratum to document cited in CA113(19):171436c]

by Dorigo, Andrea E, McCarrick, Margaret A, Loncharich, Richard J, Houk, K. N
Published in Journal of the American Chemical Society (01.05.1991)

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Journal Article

PDE2 [124][15-a]-7- SUBSTITUTED [124]TRIAZOLO[15-A]PYRIMIDIN-7-YL COMPOUNDS AS PDE2 INHIBITORS

PDE2 [124][15-a]-7- SUBSTITUTED [124]TRIAZOLO[15-A]PYRIMIDIN-7-YL COMPOUNDS AS PDE2 INHIBITORS

by BREITENBUCHER JAMES, VERNIER WILLIAM, VICKERS TROY, LY KIEV, MCCARRICK MARGARET, GOMEZ LAURENT, LEMUS ROBERT, FREESTONE GRAEME
Year of Publication 20.12.2016

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Patent

SUBSTITUTED [1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL COMPOUNDS AS PDE2 INHIBITORS

SUBSTITUTED [1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL COMPOUNDS AS PDE2 INHIBITORS

by Vickers, Troy, Breitenbucher, James, Vernier, William, Ly, Kiev, Gomez, Laurent, McCarrick, Margaret, Freestone, Graeme, Lemus, Robert
Year of Publication 22.06.2023

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Patent

Substituted furanopyrimidine compounds as PDE1 inhibitors

Substituted furanopyrimidine compounds as PDE1 inhibitors

by Raffaele, Nicholas, Kleinke, Andrew, McCarrick, Margaret, Burns, Aaron, Weinhouse, Michael, Tran, Joe, Botrous, Iriny, Chung, DeMichael, Bookser, Brett, Kumar, Dange Vijay, Dyck, Brian
Year of Publication 11.06.2024

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Patent

SUBSTITUTED [1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL COMPOUNDS AS PDE2 INHIBITORS

SUBSTITUTED [1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL COMPOUNDS AS PDE2 INHIBITORS

by MCCARRICK, MARGARET, VERNIER, WILLIAM, GOMEZ, LAURENT, FREESTONE, GRAEME, VICKERS, TROY, LEMUS, ROBERT, BREITENBUCHER, JAMES, LY, KIEV
Year of Publication 21.02.2023

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Patent

COMPOSITIONS CONTAINING SUBSTITUTED [1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL COMPOUNDS AS PDE2 INHIBITORS

COMPOSITIONS CONTAINING SUBSTITUTED [1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL COMPOUNDS AS PDE2 INHIBITORS

by Vickers, Troy, Breitenbucher, James, Vernier, William, Ly, Kiev, Gomez, Laurent, McCarrick, Margaret, Freestone, Graeme, Lemus, Robert
Year of Publication 01.04.2022

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Patent

Substituted [1,2,4] triazolo [1,5-a] pyrimidin-7-yl compounds as PDE2 inhibitors

Substituted [1,2,4] triazolo [1,5-a] pyrimidin-7-yl compounds as PDE2 inhibitors

by Vickers, Troy, Breitenbucher, James, Vernier, William, Ly, Kiev, Gomez, Laurent, McCarrick, Margaret, Freestone, Graeme, Lemus, Robert
Year of Publication 09.12.2021

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Patent