Search Results - "MCBRAYER, Tamara R" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Synthesis and Antiviral Evaluation of (1,4-Disubstituted-1,2,3-Triazol)-( E )-2-Methyl-but-2-Enyl Nucleoside Phosphonate Prodrugs

Synthesis and Antiviral Evaluation of (1,4-Disubstituted-1,2,3-Triazol)-( E )-2-Methyl-but-2-Enyl Nucleoside Phosphonate Prodrugs

by Abuduaini, Tuniyazi, Roy, Vincent, Marlet, Julien, Gaudy-Graffin, Catherine, Brand, Denys, Baronti, Cécile, Touret, Franck, Coutard, Bruno, McBrayer, Tamara R, Schinazi, Raymond F, Agrofoglio, Luigi A
Published in Molecules (Basel, Switzerland) (09.03.2021)

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Synthesis and antiviral evaluation of 2′,2′,3′,3′-tetrafluoro nucleoside analogs

Synthesis and antiviral evaluation of 2′,2′,3′,3′-tetrafluoro nucleoside analogs

by Sari, Ozkan, Bassit, Leda, Gavegnano, Christina, McBrayer, Tamara R., McCormick, Louise, Cox, Bryan, Coats, Steven J., Amblard, Franck, Schinazi, Raymond F.
Published in Tetrahedron letters (15.02.2017)

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Design, Synthesis, and Antiviral Activity of 2‘-Deoxy-2‘-fluoro-2‘-C-methylcytidine, a Potent Inhibitor of Hepatitis C Virus Replication

Design, Synthesis, and Antiviral Activity of 2‘-Deoxy-2‘-fluoro-2‘-C-methylcytidine, a Potent Inhibitor of Hepatitis C Virus Replication

by Clark, Jeremy L, Hollecker, Laurent, Mason, J. Christian, Stuyver, Lieven J, Tharnish, Phillip M, Lostia, Stefania, McBrayer, Tamara R, Schinazi, Raymond F, Watanabe, Kyoichi A, Otto, Michael J, Furman, Phillip A, Stec, Wojciech J, Patterson, Steven E, Pankiewicz, Krzysztof W
Published in Journal of medicinal chemistry (25.08.2005)

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Synthesis, evaluation of anti-HIV-1 and anti-HCV activity of novel 2′,3′-dideoxy-2′,2′-difluoro-4′-azanucleosides

Synthesis, evaluation of anti-HIV-1 and anti-HCV activity of novel 2′,3′-dideoxy-2′,2′-difluoro-4′-azanucleosides

by Martínez-Montero, Saúl, Fernández, Susana, Sanghvi, Yogesh S., Theodorakis, Emmanuel A., Detorio, Mervi A., Mcbrayer, Tamara R., Whitaker, Tony, Schinazi, Raymond F., Gotor, Vicente, Ferrero, Miguel
Published in Bioorganic & medicinal chemistry (01.12.2012)

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Mechanism of Activation of β-d-2′-Deoxy-2′-Fluoro-2′-C-Methylcytidine and Inhibition of Hepatitis C Virus NS5B RNA Polymerase

Mechanism of Activation of β-d-2′-Deoxy-2′-Fluoro-2′-C-Methylcytidine and Inhibition of Hepatitis C Virus NS5B RNA Polymerase

by MURAKAMI, Eisuke, HAIYING BAO, FURMAN, Phillip A, RAMESH, Mangala, MCBRAYER, Tamara R, WHITAKER, Tony, MICOLOCHICK STEUER, Holly M, SCHINAZI, Raymond F, STUYVER, Lieven J, OBIKHOD, Aleksandr, OTTO, Michael J
Published in Antimicrobial Agents and Chemotherapy (01.02.2007)

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Ribonucleoside Analogue That Blocks Replication of Bovine Viral Diarrhea and Hepatitis C Viruses in Culture

Ribonucleoside Analogue That Blocks Replication of Bovine Viral Diarrhea and Hepatitis C Viruses in Culture

by STUYVER, Lieven J, WHITAKER, Tony, RACHAKONDA, Suguna, WATANABE, Kyoichi A, OTTO, Michael J, SCHINAZI, Raymond F, MCBRAYER, Tamara R, HERNANDEZ-SANTIAGO, Brenda I, LOSTIA, Stefania, THARNISH, Phillip M, RAMESH, Mangala, CHU, Chung K, JORDAN, Robert, JUNXING SHI
Published in Antimicrobial Agents and Chemotherapy (01.01.2003)

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Synthesis and evaluation of Janus type nucleosides as potential HCV NS5B polymerase inhibitors

Synthesis and evaluation of Janus type nucleosides as potential HCV NS5B polymerase inhibitors

by Zhou, Longhu, Amblard, Franck, Zhang, Hongwang, McBrayer, Tamara R., Detorio, Mervi A., Whitaker, Tony, Coats, Steven J., Schinazi, Raymond F.
Published in Bioorganic & medicinal chemistry letters (01.06.2013)

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Synthesis and antiviral activity of 2′-deoxy-2′-fluoro-2′-C-methyl purine nucleosides as inhibitors of hepatitis C virus RNA replication

Synthesis and antiviral activity of 2′-deoxy-2′-fluoro-2′-C-methyl purine nucleosides as inhibitors of hepatitis C virus RNA replication

by Clark, Jeremy L., Mason, J. Christian, Hollecker, Laurent, Stuyver, Lieven J., Tharnish, Phillip M., McBrayer, Tamara R., Otto, Michael J., Furman, Phillip A., Schinazi, Raymond F., Watanabe, Kyoichi A.
Published in Bioorganic & medicinal chemistry letters (15.03.2006)

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Dynamics of Subgenomic Hepatitis C Virus Replicon RNA Levels in Huh-7 Cells after Exposure to Nucleoside Antimetabolites

Dynamics of Subgenomic Hepatitis C Virus Replicon RNA Levels in Huh-7 Cells after Exposure to Nucleoside Antimetabolites

by Stuyver, Lieven J, McBrayer, Tamara R, Tharnish, Phillip M, Hassan, Abdalla E A, Chu, Chung K, Pankiewicz, Krzysztof W, Watanabe, Kyochi A, Schinazi, Raymond F, Otto, Michael J
Published in Journal of Virology (01.10.2003)

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Inhibition of the Subgenomic Hepatitis C Virus Replicon in Huh-7 Cells by 2′-Deoxy-2′-Fluorocytidine

Inhibition of the Subgenomic Hepatitis C Virus Replicon in Huh-7 Cells by 2′-Deoxy-2′-Fluorocytidine

by Stuyver, Lieven J, McBrayer, Tamara R, Whitaker, Tony, Tharnish, Phillip M, Ramesh, Mangala, Lostia, Stefania, Cartee, Leanne, Shi, Junxing, Hobbs, Ann, Schinazi, Raymond F, Watanabe, Kyoichi A, Otto, Michael J
Published in Antimicrobial Agents and Chemotherapy (01.02.2004)

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Synthesis and anti-viral activity of a series of d- and l-2′-deoxy-2′-fluororibonucleosides in the subgenomic HCV replicon system

Synthesis and anti-viral activity of a series of d- and l-2′-deoxy-2′-fluororibonucleosides in the subgenomic HCV replicon system

by Shi, Junxing, Du, Jinfa, Ma, Tianwei, Pankiewicz, Krzysztof W., Patterson, Steven E., Tharnish, Phillip M., McBrayer, Tamara R., Stuyver, Lieven J., Otto, Michael J., Chu, Chung K., Schinazi, Raymond F., Watanabe, Kyoichi A.
Published in Bioorganic & medicinal chemistry (01.03.2005)

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Asymmetric Binding to NS5A by Daclatasvir (BMS-790052) and Analogs Suggests Two Novel Modes of HCV Inhibition

Asymmetric Binding to NS5A by Daclatasvir (BMS-790052) and Analogs Suggests Two Novel Modes of HCV Inhibition

by Nettles, James H, Stanton, Richard A, Broyde, Joshua, Amblard, Franck, Zhang, Hongwang, Zhou, Longhu, Shi, Junxing, McBrayer, Tamara R, Whitaker, Tony, Coats, Steven J, Kohler, James J, Schinazi, Raymond F
Published in Journal of medicinal chemistry (11.12.2014)

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Synthesis and anti-HCV activity of a series of β-d-2′-deoxy-2′-dibromo nucleosides and their corresponding phosphoramidate prodrugs

Synthesis and anti-HCV activity of a series of β-d-2′-deoxy-2′-dibromo nucleosides and their corresponding phosphoramidate prodrugs

by Chen, Zhe, Cox, Bryan D., Garnier-Amblard, Ethel C., McBrayer, Tamara R., Coats, Steven J., Schinazi, Raymond F., Amblard, Franck
Published in Bioorganic & medicinal chemistry letters (01.12.2017)

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Preparation of ribavirin analogues by copper- and ruthenium-catalyzed azide-alkyne 1,3-dipolar cycloaddition

Preparation of ribavirin analogues by copper- and ruthenium-catalyzed azide-alkyne 1,3-dipolar cycloaddition

by Pradere, Ugo, Roy, Vincent, McBrayer, Tamara R., Schinazi, Raymond F., Agrofoglio, Luigi A.
Published in Tetrahedron (15.09.2008)

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β‑d‑2′‑C‑Methyl-2,6-diaminopurine Ribonucleoside Phosphoramidates are Potent and Selective Inhibitors of Hepatitis C Virus (HCV) and Are Bioconverted Intracellularly to Bioactive 2,6-Diaminopurine and Guanosine 5′-Triphosphate Forms

β‑d‑2′‑C‑Methyl-2,6-diaminopurine Ribonucleoside Phosphoramidates are Potent and Selective Inhibitors of Hepatitis C Virus (HCV) and Are Bioconverted Intracellularly to Bioactive 2,6-Diaminopurine and Guanosine 5′-Triphosphate Forms

by Zhou, Longhu, Zhang, Hong-wang, Tao, Sijia, Bassit, Leda, Whitaker, Tony, McBrayer, Tamara R, Ehteshami, Maryam, Amiralaei, Sheida, Pradere, Ugo, Cho, Jong Hyun, Amblard, Franck, Bobeck, Drew, Detorio, Mervi, Coats, Steven J, Schinazi, Raymond F
Published in Journal of medicinal chemistry (23.04.2015)

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Nucleotide Substrate Specificity of Anti-Hepatitis C Virus Nucleoside Analogs for Human Mitochondrial RNA Polymerase

Nucleotide Substrate Specificity of Anti-Hepatitis C Virus Nucleoside Analogs for Human Mitochondrial RNA Polymerase

by Ehteshami, Maryam, Zhou, Longhu, Amiralaei, Sheida, Shelton, Jadd R, Cho, Jong Hyun, Zhang, Hongwang, Li, Hao, Lu, Xiao, Ozturk, Tugba, Stanton, Richard, Amblard, Franck, McBrayer, Tamara R, Coats, Steven J, Schinazi, Raymond F
Published in Antimicrobial agents and chemotherapy (01.08.2017)

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Antiviral activity of nucleoside analogues against norovirus

Antiviral activity of nucleoside analogues against norovirus

by COSTANTINI, Verónica P, WHITAKER, Tony, BARCLAY, Leslie, LEE, David, MCBRAYER, Tamara R, SCHINAZI, Raymond F, VINJE, Jan
Published in Antiviral therapy (01.01.2012)

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Synthesis and broad spectrum antiviral evaluation of bis(POM) prodrugs of novel acyclic nucleosides

Synthesis and broad spectrum antiviral evaluation of bis(POM) prodrugs of novel acyclic nucleosides

by Hamada, Manabu, Roy, Vincent, McBrayer, Tamara R., Whitaker, Tony, Urbina-Blanco, Cesar, Nolan, Steven P., Balzarini, Jan, Snoeck, Robert, Andrei, Graciela, Schinazi, Raymond F., Agrofoglio, Luigi A.
Published in European journal of medicinal chemistry (01.09.2013)

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Design, synthesis and evaluation of novel anti-HCV molecules that deliver intracellularly three highly potent NS5A inhibitors

Design, synthesis and evaluation of novel anti-HCV molecules that deliver intracellularly three highly potent NS5A inhibitors

by Boucle, Sebastien, Tao, Sijia, Amblard, Franck, Stanton, Richard A., Nettles, James H., Li, Chengwei, McBrayer, Tamara R., Whitaker, Tony, Coats, Steven J., Schinazi, Raymond F.
Published in Bioorganic & medicinal chemistry letters (01.09.2015)

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Synthesis and Evaluation of 2,6-Modified Purine 2′‑C‑Methyl Ribonucleosides as Inhibitors of HCV Replication

Synthesis and Evaluation of 2,6-Modified Purine 2′‑C‑Methyl Ribonucleosides as Inhibitors of HCV Replication

by Zhou, Longhu, Zhang, Hongwang, Tao, Sijia, Ehteshami, Maryam, Cho, Jong Hyun, McBrayer, Tamara R, Tharnish, Philip, Whitaker, Tony, Amblard, Franck, Coats, Steven J, Schinazi, Raymond F
Published in ACS medicinal chemistry letters (14.01.2016)

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