Chitinases and Chitinase-Like Proteins as Therapeutic Targets in Inflammatory Diseases, with a Special Focus on Inflammatory Bowel Diseases
Mazur, Marzena, Zielińska, Anna, Grzybowski, Marcin M., Olczak, Jacek, Fichna, Jakub
Published in International journal of molecular sciences (01.07.2021)
Published in International journal of molecular sciences (01.07.2021)
Get full text
Journal Article
The Anti-Inflammatory Effect of Acidic Mammalian Chitinase Inhibitor OAT-177 in DSS-Induced Mouse Model of Colitis
Mazur, Marzena, Włodarczyk, Jakub, Świerczyński, Mikołaj, Kordek, Radzisław, Grzybowski, Marcin M, Olczak, Jacek, Fichna, Jakub
Published in International journal of molecular sciences (15.02.2022)
Published in International journal of molecular sciences (15.02.2022)
Get full text
Journal Article
Inhibition of Macrophage-Specific CHIT1 as an Approach to Treat Airway Remodeling in Severe Asthma
Sklepkiewicz, Piotr, Dymek, Barbara, Mlacki, Michal, Zagozdzon, Agnieszka, Salamon, Magdalena, Siwińska, Anna Maria, Mazurkiewicz, Marcin Piotr, de Souza Xavier Costa, Natalia, Mazur, Marzena, Mauad, Thais, Gołębiowski, Adam, Dzwonek, Karolina, Gołąb, Jakub, Zasłona, Zbigniew
Published in International journal of molecular sciences (01.03.2023)
Published in International journal of molecular sciences (01.03.2023)
Get full text
Journal Article
Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma
Mazur, Marzena, Olczak, Jacek, Olejniczak, Sylwia, Koralewski, Robert, Czestkowski, Wojciech, Jedrzejczak, Anna, Golab, Jakub, Dzwonek, Karolina, Dymek, Barbara, Sklepkiewicz, Piotr L, Zagozdzon, Agnieszka, Noonan, Tom, Mahboubi, Keyvan, Conway, Bruce, Sheeler, Ryan, Beckett, Paul, Hungerford, William M, Podjarny, Alberto, Mitschler, Andre, Cousido-Siah, Alexandra, Fadel, Firas, Golebiowski, Adam
Published in Journal of medicinal chemistry (08.02.2018)
Published in Journal of medicinal chemistry (08.02.2018)
Get full text
Journal Article
Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase
Mazur, Marzena, Bartoszewicz, Agnieszka, Dymek, Barbara, Salamon, Magdalena, Andryianau, Gleb, Kowalski, Michał, Olejniczak, Sylwia, Matyszewski, Krzysztof, Pluta, Elżbieta, Borek, Bartłomiej, Stefaniak, Filip, Zagozdzon, Agnieszka, Mazurkiewicz, Marcin, Koralewski, Robert, Czestkowski, Wojciech, Piotrowicz, Michał, Niedziejko, Piotr, Gruza, Mariusz M., Dzwonek, Karolina, Golebiowski, Adam, Golab, Jakub, Olczak, Jacek
Published in Bioorganic & medicinal chemistry letters (01.02.2018)
Published in Bioorganic & medicinal chemistry letters (01.02.2018)
Get full text
Journal Article
The Role of Nonenhanced Magnetic Resonance Imaging in the Early Assessment of Acute Pancreatitis
STIMAC, Davor, MILETIC, Damir, RADIC, Mladen, KRZNARIC, Irena, MAZUR-GRBAC, Marzena, PERKOVIC, Domagoj, MILIC, Sandra, GOLUBOVIC, Vesna
Published in The American journal of gastroenterology (01.05.2007)
Published in The American journal of gastroenterology (01.05.2007)
Get full text
Journal Article
Role of Magnetic Resonance Cholangiography in the Diagnosis of Bile Duct Lithiasis
Miletic, Damir, Uravic, Miljenko, Mazur‐Brbac, Marzena, Stimac, Davor, Petranovic, Davor, Sestan, Branko
Published in World journal of surgery (01.09.2006)
Published in World journal of surgery (01.09.2006)
Get full text
Journal Article
Therapeutic efficacy of the chitotriosidase inhibitors in STAM model of non-alcoholic steatohepatitis
Mlacki, Michal, Dymek, Barbara, Zagozdzon, Agnieszka, Mazur, Marzena, Koralewski, Robert, Golebiewski, Adam, Dzwonek, Karolina, Dobrzanski, Pawel
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
Get full text
Journal Article
FRI105 - Therapeutic efficacy of the chitotriosidase inhibitors in STAM model of non-alcoholic steatohepatitis
Mlacki, Michal, Dymek, Barbara, Zagozdzon, Agnieszka, Mazur, Marzena, Koralewski, Robert, Golebiewski, Adam, Dzwonek, Karolina, Dobrzanski, Pawel
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
Get full text
Journal Article
Cyclic derivatives of morphiceptin possess anti-transit effect in the gastrointestinal tract and alleviate abdominal pain in mice
Szymaszkiewicz, Agata, Włodarczyk, Jakub, Mazur, Marzena, Olczak, Jacek, Fichna, Jakub, Zielińska, Marta
Published in Pharmacological reports (01.04.2020)
Published in Pharmacological reports (01.04.2020)
Get full text
Journal Article
Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis
Koralewski, Robert, Dymek, Barbara, Mazur, Marzena, Sklepkiewicz, Piotr, Olejniczak, Sylwia, Czestkowski, Wojciech, Matyszewski, Krzysztof, Andryianau, Gleb, Niedziejko, Piotr, Kowalski, Michal, Gruza, Mariusz, Borek, Bartłomiej, Jedrzejczak, Karol, Bartoszewicz, Agnieszka, Pluta, Elżbieta, Rymaszewska, Aleksandra, Kania, Magdalena, Rejczak, Tomasz, Piasecka, Sylwia, Mlacki, Michal, Mazurkiewicz, Marcin, Piotrowicz, Michał, Salamon, Magdalena, Zagozdzon, Agnieszka, Napiorkowska-Gromadzka, Agnieszka, Bartlomiejczak, Aneta, Mozga, Witold, Dobrzański, Paweł, Dzwonek, Karolina, Golab, Jakub, Nowotny, Marcin, Olczak, Jacek, Golebiowski, Adam
Published in Journal of medicinal chemistry (24.12.2020)
Published in Journal of medicinal chemistry (24.12.2020)
Get full text
Journal Article
Structure-Based Discovery of High-Affinity Small Molecule Ligands and Development of Tool Probes to Study the Role of Chitinase-3-Like Protein 1
Czestkowski, Wojciech, Krzemiński, Łukasz, Piotrowicz, Michał C., Mazur, Marzena, Pluta, Elżbieta, Andryianau, Gleb, Koralewski, Robert, Matyszewski, Krzysztof, Olejniczak, Sylwia, Kowalski, Michał, Lisiecka, Katarzyna, Kozieł, Rafał, Piwowar, Katarzyna, Papiernik, Diana, Nowotny, Marcin, Napiórkowska-Gromadzka, Agnieszka, Nowak, Elżbieta, Niedziałek, Dorota, Wieczorek, Grzegorz, Siwińska, Anna, Rejczak, Tomasz, Jędrzejczak, Karol, Mulewski, Krzysztof, Olczak, Jacek, Zasłona, Zbigniew, Gołębiowski, Adam, Drzewicka, Katarzyna, Bartoszewicz, Agnieszka
Published in Journal of medicinal chemistry (14.03.2024)
Published in Journal of medicinal chemistry (14.03.2024)
Get full text
Journal Article
Inhibition of CHIT1 as a novel therapeutic approach in idiopathic pulmonary fibrosis
Sklepkiewicz, Piotr, Dymek, Barbara A., Mlacki, Michal, Koralewski, Robert, Mazur, Marzena, Nejman-Gryz, Patrycja, Korur, Serdar, Zagozdzon, Agnieszka, Rymaszewska, Aleksandra, von der Thüsen, Jan H., Siwińska, Anna M., Güner, Nazan Cemre, Cheda, Łukasz, Paplinska-Goryca, Magdalena, Proboszcz, Małgorzata, van den Bosch, Thierry P.P., Górska, Katarzyna, Golab, Jakub, Kamiński, Rafał M., Krenke, Rafał, Golebiowski, Adam, Dzwonek, Karolina, Dobrzanski, Pawel
Published in European journal of pharmacology (15.03.2022)
Published in European journal of pharmacology (15.03.2022)
Get full text
Journal Article
Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases
Mazur, Marzena, Dymek, Barbara, Koralewski, Robert, Sklepkiewicz, Piotr, Olejniczak, Sylwia, Mazurkiewicz, Marcin, Piotrowicz, Michał, Salamon, Magdalena, Jędrzejczak, Karol, Zagozdzon, Agnieszka, Czestkowski, Wojciech, Matyszewski, Krzysztof, Borek, Bartłomiej, Bartoszewicz, Agnieszka, Pluta, Elżbieta, Rymaszewska, Aleksandra, Mozga, Witold, Stefaniak, Filip, Dobrzański, Paweł, Dzwonek, Karolina, Golab, Jakub, Golebiowski, Adam, Olczak, Jacek
Published in Journal of medicinal chemistry (08.08.2019)
Published in Journal of medicinal chemistry (08.08.2019)
Get full text
Journal Article
Antinociceptive and antidepressant-like action of endomorphin-2 analogs with proline surrogates in position 2
Perlikowska, Renata, Piekielna, Justyna, Mazur, Marzena, Koralewski, Robert, Olczak, Jacek, do Rego, Jean-Claude, Fichna, Jakub, Modranka, Jakub, Janecki, Tomasz, Janecka, Anna
Published in Bioorganic & medicinal chemistry (01.09.2014)
Published in Bioorganic & medicinal chemistry (01.09.2014)
Get full text
Journal Article
Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase
Andryianau, Gleb, Kowalski, Michal, Piotrowicz, Michal C., Rajkiewicz, Adam A., Dymek, Barbara, Sklepkiewicz, Piotr L., Pluta, Elzbieta, Stefaniak, Filip, Czestkowski, Wojciech, Olejniczak, Sylwia, Mazur, Marzena, Niedziejko, Piotr, Koralewski, Robert, Matyszewski, Krzysztof, Gruza, Mariusz, Zagozdzon, Agnieszka, Salamon, Magdalena, Rymaszewska, Aleksandra, Welzer, Mikolaj, Dzwonek, Karolina, Golab, Jakub, Olczak, Jacek, Bartoszewicz, Agnieszka, Golebiowski, Adam
Published in ACS medicinal chemistry letters (11.06.2020)
Published in ACS medicinal chemistry letters (11.06.2020)
Get full text
Journal Article
Novel glycosylated endomorphin-2 analog produces potent centrally-mediated antinociception in mice after peripheral administration
Fichna, Jakub, Mazur, Marzena, Grzywacz, Daria, Kamysz, Wojciech, Perlikowska, Renata, Piekielna, Justyna, Sobczak, Marta, Sałaga, Maciej, Toth, Geza, Janecka, Anna, Chen, Chunqiu, Olczak, Jacek
Published in Bioorganic & medicinal chemistry letters (15.12.2013)
Published in Bioorganic & medicinal chemistry letters (15.12.2013)
Get full text
Journal Article
Synthesis of quaternary α-amino acid-based arginase inhibitors via the Ugi reaction
Golebiowski, Adam, Whitehouse, Darren, Beckett, R. Paul, Van Zandt, Michael, Ji, Min Koo, Ryder, Todd R., Jagdmann, Erik, Andreoli, Monica, Lee, Yung, Sheeler, Ryan, Conway, Bruce, Olczak, Jacek, Mazur, Marzena, Czestkowski, Wojciech, Piotrowska, Wieslawa, Cousido-Siah, Alexandra, Ruiz, Francesc X., Mitschler, Andre, Podjarny, Alberto, Schroeter, Hagen
Published in Bioorganic & medicinal chemistry letters (01.09.2013)
Published in Bioorganic & medicinal chemistry letters (01.09.2013)
Get full text
Journal Article
Cyclic side-chain-linked opioid analogs utilizing cis- and trans-4-aminocyclohexyl-d-alanine
Piekielna, Justyna, Gentilucci, Luca, De Marco, Rossella, Perlikowska, Renata, Adamska, Anna, Olczak, Jacek, Mazur, Marzena, Artali, Roberto, Modranka, Jakub, Janecki, Tomasz, Tömböly, Csaba, Janecka, Anna
Published in Bioorganic & medicinal chemistry (01.12.2014)
Published in Bioorganic & medicinal chemistry (01.12.2014)
Get full text
Journal Article
키티나제 억제제로서 유용한 치환된 아미노 트리아졸
JOACHIMIAK LUKASZ, MAZUR MARZENA, CZESTKOWSKI WOJCIECH, KOWALSKI MICHAL, GOLEBIOWSKI ADAM, OLEJNICZAK SYLWIA, OLCZAK JACEK, BARTOSZEWICZ AGNIESZKA, KORALEWSKI ROBERT, MATYSZEWSKI KRZYSZTOF, ANDRYIANAU GLEB, NIEDZIEJKO PIOTR
Year of Publication 05.04.2022
Get full text
Year of Publication 05.04.2022
Patent