Advances in recombinant protein expression for use in pharmaceutical research
Assenberg, Rene, Wan, Paul T, Geisse, Sabine, Mayr, Lorenz M
Published in Current opinion in structural biology (01.06.2013)
Published in Current opinion in structural biology (01.06.2013)
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Journal Article
In vivo CRISPR editing with no detectable genome-wide off-target mutations
Akcakaya, Pinar, Bobbin, Maggie L., Guo, Jimmy A., Malagon-Lopez, Jose, Clement, Kendell, Garcia, Sara P., Fellows, Mick D., Porritt, Michelle J., Firth, Mike A., Carreras, Alba, Baccega, Tania, Seeliger, Frank, Bjursell, Mikael, Tsai, Shengdar Q., Nguyen, Nhu T., Nitsch, Roberto, Mayr, Lorenz M., Pinello, Luca, Bohlooly-Y, Mohammad, Aryee, Martin J., Maresca, Marcello, Joung, J. Keith
Published in Nature (London) (01.09.2018)
Published in Nature (London) (01.09.2018)
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Journal Article
Decoding non-random mutational signatures at Cas9 targeted sites
Taheri-Ghahfarokhi, Amir, Taylor, Benjamin J M, Nitsch, Roberto, Lundin, Anders, Cavallo, Anna-Lina, Madeyski-Bengtson, Katja, Karlsson, Fredrik, Clausen, Maryam, Hicks, Ryan, Mayr, Lorenz M, Bohlooly-Y, Mohammad, Maresca, Marcello
Published in Nucleic acids research (19.09.2018)
Published in Nucleic acids research (19.09.2018)
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Journal Article
Coaxing Solid-State Phosphorescence from Tellurophenes
He, Gang, Torres Delgado, William, Schatz, Devon J., Merten, Christian, Mohammadpour, Arash, Mayr, Lorenz, Ferguson, Michael J., McDonald, Robert, Brown, Alex, Shankar, Karthik, Rivard, Eric
Published in Angewandte Chemie (International ed.) (25.04.2014)
Published in Angewandte Chemie (International ed.) (25.04.2014)
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Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery
Lundin, Anders, Porritt, Michelle J., Jaiswal, Himjyot, Seeliger, Frank, Johansson, Camilla, Bidar, Abdel Wahad, Badertscher, Lukas, Wimberger, Sandra, Davies, Emma J., Hardaker, Elizabeth, Martins, Carla P., James, Emily, Admyre, Therese, Taheri-Ghahfarokhi, Amir, Bradley, Jenna, Schantz, Anna, Alaeimahabadi, Babak, Clausen, Maryam, Xu, Xiufeng, Mayr, Lorenz M., Nitsch, Roberto, Bohlooly-Y, Mohammad, Barry, Simon T., Maresca, Marcello
Published in Nature communications (29.09.2020)
Published in Nature communications (29.09.2020)
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Engineered Cas9 extracellular vesicles as a novel gene editing tool
Osteikoetxea, Xabier, Silva, Andreia, Lázaro‐Ibáñez, Elisa, Salmond, Nikki, Shatnyeva, Olga, Stein, Josia, Schick, Jan, Wren, Stephen, Lindgren, Julia, Firth, Mike, Madsen, Alexandra, Mayr, Lorenz M., Overman, Ross, Davies, Rick, Dekker, Niek
Published in Journal of extracellular vesicles (01.05.2022)
Published in Journal of extracellular vesicles (01.05.2022)
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Journal Article
In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model
Carreras, Alba, Pane, Luna Simona, Nitsch, Roberto, Madeyski-Bengtson, Katja, Porritt, Michelle, Akcakaya, Pinar, Taheri-Ghahfarokhi, Amir, Ericson, Elke, Bjursell, Mikael, Perez-Alcazar, Marta, Seeliger, Frank, Althage, Magnus, Knöll, Ralph, Hicks, Ryan, Mayr, Lorenz M, Perkins, Rosie, Lindén, Daniel, Borén, Jan, Bohlooly-Y, Mohammad, Maresca, Marcello
Published in BMC biology (15.01.2019)
Published in BMC biology (15.01.2019)
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Blocking phospholamban with VHH intrabodies enhances contractility and relaxation in heart failure
De Genst, Erwin, Foo, Kylie S., Xiao, Yao, Rohner, Eduarde, de Vries, Emma, Sohlmér, Jesper, Witman, Nevin, Hidalgo, Alejandro, Kolstad, Terje R. S., Louch, William E., Pehrsson, Susanne, Park, Andrew, Ikeda, Yasuhiro, Li, Xidan, Mayr, Lorenz M., Wickson, Kate, Jennbacken, Karin, Hansson, Kenny, Fritsche-Danielson, Regina, Hunt, James, Chien, Kenneth R.
Published in Nature communications (31.05.2022)
Published in Nature communications (31.05.2022)
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Secretome screening reveals immunomodulating functions of IFNα-7, PAP and GDF-7 on regulatory T-cells
Ding, Mei, Malhotra, Rajneesh, Ottosson, Tomas, Lundqvist, Magnus, Mebrahtu, Aman, Brengdahl, Johan, Gehrmann, Ulf, Bäck, Elisabeth, Ross-Thriepland, Douglas, Isaksson, Ida, Magnusson, Björn, Sachsenmeier, Kris F., Tegel, Hanna, Hober, Sophia, Uhlén, Mathias, Mayr, Lorenz M., Davies, Rick, Rockberg, Johan, Schiavone, Lovisa Holmberg
Published in Scientific reports (18.08.2021)
Published in Scientific reports (18.08.2021)
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Journal Article
Therapeutic Genome Editing With CRISPR/Cas9 in a Humanized Mouse Model Ameliorates α1-antitrypsin Deficiency Phenotype
Bjursell, Mikael, Porritt, Michelle J., Ericson, Elke, Taheri-Ghahfarokhi, Amir, Clausen, Maryam, Magnusson, Lisa, Admyre, Therese, Nitsch, Roberto, Mayr, Lorenz, Aasehaug, Leif, Seeliger, Frank, Maresca, Marcello, Bohlooly-Y, Mohammad, Wiseman, John
Published in EBioMedicine (01.03.2018)
Published in EBioMedicine (01.03.2018)
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High throughput generation of a resource of the human secretome in mammalian cells
Tegel, Hanna, Dannemeyer, Melanie, Kanje, Sara, Sivertsson, Åsa, Berling, Anna, Svensson, Anne-Sophie, Hober, Andreas, Enstedt, Henric, Volk, Anna-Luisa, Lundqvist, Magnus, Moradi, Mona, Afshari, Delaram, Ekblad, Siri, Xu, LanLan, Westin, Malin, Bidad, Faranak, Schiavone, Lovisa Holmberg, Davies, Rick, Mayr, Lorenz M., Knight, Sinead, Göpel, Sven O., Voldborg, Björn G., Edfors, Fredrik, Forsström, Björn, von Feilitzen, Kalle, Zwahlen, Martin, Rockberg, Johan, Takanen, Jenny Ottosson, Uhlén, Mathias, Hober, Sophia
Published in New biotechnology (25.09.2020)
Published in New biotechnology (25.09.2020)
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Endosomal escape enhancing compounds facilitate functional delivery of extracellular vesicle cargo
Heath, Nikki, Osteikoetxea, Xabier, de Oliveria, Taiana Mia, Lázaro-Ibáñez, Elisa, Shatnyeva, Olga, Schindler, Christina, Tigue, Natalie, Mayr, Lorenz M, Dekker, Niek, Overman, Ross, Davies, Rick
Published in Nanomedicine (London, England) (01.11.2019)
Published in Nanomedicine (London, England) (01.11.2019)
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Single fluorescent protein-based Ca2+ sensors with increased dynamic range
Souslova, Ekaterina A, Belousov, Vsevolod V, Lock, John G, Strömblad, Staffan, Kasparov, Sergey, Bolshakov, Alexey P, Pinelis, Vsevolod G, Labas, Yulii A, Lukyanov, Sergey, Mayr, Lorenz M, Chudakov, Dmitriy M
Published in BMC biotechnology (29.06.2007)
Published in BMC biotechnology (29.06.2007)
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Journal Article
Fragment-Based Screening by Biochemical Assays: Systematic Feasibility Studies with Trypsin and MMP12
Boettcher, Andreas, Ruedisser, Simon, Erbel, Paulus, Vinzenz, Daniela, Schiering, Nikolaus, Hassiepen, Ulrich, Rigollier, Pascal, Mayr, Lorenz M., Woelcke, Julian
Published in Journal of biomolecular screening (01.10.2010)
Published in Journal of biomolecular screening (01.10.2010)
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