Advances in recombinant protein expression for use in pharmaceutical research
Assenberg, Rene, Wan, Paul T, Geisse, Sabine, Mayr, Lorenz M
Published in Current opinion in structural biology (01.06.2013)
Published in Current opinion in structural biology (01.06.2013)
Get full text
Journal Article
Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery
Lundin, Anders, Porritt, Michelle J., Jaiswal, Himjyot, Seeliger, Frank, Johansson, Camilla, Bidar, Abdel Wahad, Badertscher, Lukas, Wimberger, Sandra, Davies, Emma J., Hardaker, Elizabeth, Martins, Carla P., James, Emily, Admyre, Therese, Taheri-Ghahfarokhi, Amir, Bradley, Jenna, Schantz, Anna, Alaeimahabadi, Babak, Clausen, Maryam, Xu, Xiufeng, Mayr, Lorenz M., Nitsch, Roberto, Bohlooly-Y, Mohammad, Barry, Simon T., Maresca, Marcello
Published in Nature communications (29.09.2020)
Published in Nature communications (29.09.2020)
Get full text
Journal Article
Engineered Cas9 extracellular vesicles as a novel gene editing tool
Osteikoetxea, Xabier, Silva, Andreia, Lázaro‐Ibáñez, Elisa, Salmond, Nikki, Shatnyeva, Olga, Stein, Josia, Schick, Jan, Wren, Stephen, Lindgren, Julia, Firth, Mike, Madsen, Alexandra, Mayr, Lorenz M., Overman, Ross, Davies, Rick, Dekker, Niek
Published in Journal of extracellular vesicles (01.05.2022)
Published in Journal of extracellular vesicles (01.05.2022)
Get full text
Journal Article
In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model
Carreras, Alba, Pane, Luna Simona, Nitsch, Roberto, Madeyski-Bengtson, Katja, Porritt, Michelle, Akcakaya, Pinar, Taheri-Ghahfarokhi, Amir, Ericson, Elke, Bjursell, Mikael, Perez-Alcazar, Marta, Seeliger, Frank, Althage, Magnus, Knöll, Ralph, Hicks, Ryan, Mayr, Lorenz M, Perkins, Rosie, Lindén, Daniel, Borén, Jan, Bohlooly-Y, Mohammad, Maresca, Marcello
Published in BMC biology (15.01.2019)
Published in BMC biology (15.01.2019)
Get full text
Journal Article
Blocking phospholamban with VHH intrabodies enhances contractility and relaxation in heart failure
De Genst, Erwin, Foo, Kylie S., Xiao, Yao, Rohner, Eduarde, de Vries, Emma, Sohlmér, Jesper, Witman, Nevin, Hidalgo, Alejandro, Kolstad, Terje R. S., Louch, William E., Pehrsson, Susanne, Park, Andrew, Ikeda, Yasuhiro, Li, Xidan, Mayr, Lorenz M., Wickson, Kate, Jennbacken, Karin, Hansson, Kenny, Fritsche-Danielson, Regina, Hunt, James, Chien, Kenneth R.
Published in Nature communications (31.05.2022)
Published in Nature communications (31.05.2022)
Get full text
Journal Article
Secretome screening reveals immunomodulating functions of IFNα-7, PAP and GDF-7 on regulatory T-cells
Ding, Mei, Malhotra, Rajneesh, Ottosson, Tomas, Lundqvist, Magnus, Mebrahtu, Aman, Brengdahl, Johan, Gehrmann, Ulf, Bäck, Elisabeth, Ross-Thriepland, Douglas, Isaksson, Ida, Magnusson, Björn, Sachsenmeier, Kris F., Tegel, Hanna, Hober, Sophia, Uhlén, Mathias, Mayr, Lorenz M., Davies, Rick, Rockberg, Johan, Schiavone, Lovisa Holmberg
Published in Scientific reports (18.08.2021)
Published in Scientific reports (18.08.2021)
Get full text
Journal Article
In vivo CRISPR editing with no detectable genome-wide off-target mutations
Akcakaya, Pinar, Bobbin, Maggie L., Guo, Jimmy A., Malagon-Lopez, Jose, Clement, Kendell, Garcia, Sara P., Fellows, Mick D., Porritt, Michelle J., Firth, Mike A., Carreras, Alba, Baccega, Tania, Seeliger, Frank, Bjursell, Mikael, Tsai, Shengdar Q., Nguyen, Nhu T., Nitsch, Roberto, Mayr, Lorenz M., Pinello, Luca, Bohlooly-Y, Mohammad, Aryee, Martin J., Maresca, Marcello, Joung, J. Keith
Published in Nature (London) (01.09.2018)
Published in Nature (London) (01.09.2018)
Get full text
Journal Article
Single fluorescent protein-based Ca2+ sensors with increased dynamic range
Souslova, Ekaterina A, Belousov, Vsevolod V, Lock, John G, Strömblad, Staffan, Kasparov, Sergey, Bolshakov, Alexey P, Pinelis, Vsevolod G, Labas, Yulii A, Lukyanov, Sergey, Mayr, Lorenz M, Chudakov, Dmitriy M
Published in BMC biotechnology (29.06.2007)
Published in BMC biotechnology (29.06.2007)
Get full text
Journal Article
Suppressor of Cytokine Signaling-3 Is Recruited to the Activated Granulocyte-Colony Stimulating Factor Receptor and Modulates its Signal Transduction
Hortner, Michael, Nielsch, Ulrich, Mayr, Lorenz M, Johnston, James A, Heinrich, Peter C, Haan, Serge
Published in The Journal of immunology (1950) (01.08.2002)
Published in The Journal of immunology (1950) (01.08.2002)
Get full text
Journal Article
Decoding non-random mutational signatures at Cas9 targeted sites
Taheri-Ghahfarokhi, Amir, Taylor, Benjamin J M, Nitsch, Roberto, Lundin, Anders, Cavallo, Anna-Lina, Madeyski-Bengtson, Katja, Karlsson, Fredrik, Clausen, Maryam, Hicks, Ryan, Mayr, Lorenz M, Bohlooly-Y, Mohammad, Maresca, Marcello
Published in Nucleic acids research (19.09.2018)
Published in Nucleic acids research (19.09.2018)
Get full text
Journal Article
The structure of Ca2+ sensor Case16 reveals the mechanism of reaction to low Ca2+ concentrations
Leder, Lukas, Stark, Wilhelm, Freuler, Felix, Marsh, May, Meyerhofer, Marco, Stettler, Thomas, Mayr, Lorenz M, Britanova, Olga V, Strukova, Lydia A, Chudakov, Dmitriy M, Souslova, Ekaterina A
Published in Sensors (Basel, Switzerland) (01.09.2010)
Published in Sensors (Basel, Switzerland) (01.09.2010)
Get full text
Journal Article
Time reduction and process optimization of the baculovirus expression system for more efficient recombinant protein production in insect cells
Philipps, Björn, Rotmann, Daniel, Wicki, Micha, Mayr, Lorenz M, Forstner, Michael
Published in Protein expression and purification (01.07.2005)
Published in Protein expression and purification (01.07.2005)
Get full text
Journal Article
High throughput generation of a resource of the human secretome in mammalian cells
Tegel, Hanna, Dannemeyer, Melanie, Kanje, Sara, Sivertsson, Åsa, Berling, Anna, Svensson, Anne-Sophie, Hober, Andreas, Enstedt, Henric, Volk, Anna-Luisa, Lundqvist, Magnus, Moradi, Mona, Afshari, Delaram, Ekblad, Siri, Xu, LanLan, Westin, Malin, Bidad, Faranak, Schiavone, Lovisa Holmberg, Davies, Rick, Mayr, Lorenz M., Knight, Sinead, Göpel, Sven O., Voldborg, Björn G., Edfors, Fredrik, Forsström, Björn, von Feilitzen, Kalle, Zwahlen, Martin, Rockberg, Johan, Takanen, Jenny Ottosson, Uhlén, Mathias, Hober, Sophia
Published in New biotechnology (25.09.2020)
Published in New biotechnology (25.09.2020)
Get full text
Journal Article
Endosomal escape enhancing compounds facilitate functional delivery of extracellular vesicle cargo
Heath, Nikki, Osteikoetxea, Xabier, de Oliveria, Taiana Mia, Lázaro-Ibáñez, Elisa, Shatnyeva, Olga, Schindler, Christina, Tigue, Natalie, Mayr, Lorenz M, Dekker, Niek, Overman, Ross, Davies, Rick
Published in Nanomedicine (London, England) (01.11.2019)
Published in Nanomedicine (London, England) (01.11.2019)
Get full text
Journal Article