An androgen receptor N-terminal domain antagonist for treating prostate cancer
Myung, Jae-Kyung, Banuelos, Carmen A, Fernandez, Javier Garcia, Mawji, Nasrin R, Wang, Jun, Tien, Amy H, Yang, Yu Chi, Tavakoli, Iran, Haile, Simon, Watt, Kate, McEwan, Iain J, Plymate, Stephen, Andersen, Raymond J, Sadar, Marianne D
Published in The Journal of clinical investigation (01.07.2013)
Published in The Journal of clinical investigation (01.07.2013)
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Journal Article
Regression of Castrate-Recurrent Prostate Cancer by a Small-Molecule Inhibitor of the Amino-Terminus Domain of the Androgen Receptor
Andersen, Raymond J., Mawji, Nasrin R., Wang, Jun, Wang, Gang, Haile, Simon, Myung, Jae-Kyung, Watt, Kate, Tam, Teresa, Yang, Yu Chi, Bañuelos, Carmen A., Williams, David E., McEwan, Iain J., Wang, Yuzhou, Sadar, Marianne D.
Published in Cancer cell (15.06.2010)
Published in Cancer cell (15.06.2010)
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Journal Article
Cotargeting Androgen Receptor Splice Variants and mTOR Signaling Pathway for the Treatment of Castration-Resistant Prostate Cancer
Kato, Minoru, Banuelos, Carmen A, Imamura, Yusuke, Leung, Jacky K, Caley, Daniel P, Wang, Jun, Mawji, Nasrin R, Sadar, Marianne D
Published in Clinical cancer research (01.06.2016)
Published in Clinical cancer research (01.06.2016)
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Journal Article
Ralaniten Sensitizes Enzalutamide-Resistant Prostate Cancer to Ionizing Radiation in Prostate Cancer Cells that Express Androgen Receptor Splice Variants
Banuelos, Carmen A., Ito, Yusuke, Obst, Jon K., Mawji, Nasrin R., Wang, Jun, Hirayama, Yukiyoshi, Leung, Jacky K., Tam, Teresa, Tien, Amy H., Andersen, Raymond J., Sadar, Marianne D.
Published in Cancers (21.07.2020)
Published in Cancers (21.07.2020)
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Journal Article
Ligand-independent Activation of the Androgen Receptor by Interleukin-6 and the Role of Steroid Receptor Coactivator-1 in Prostate Cancer Cells
Ueda, Takeshi, Mawji, Nasrin R., Bruchovsky, Nicholas, Sadar, Marianne D.
Published in The Journal of biological chemistry (11.10.2002)
Published in The Journal of biological chemistry (11.10.2002)
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Journal Article
Differential Gene Expression Profiles between N-Terminal Domain and Ligand-Binding Domain Inhibitors of Androgen Receptor Reveal Ralaniten Induction of Metallothionein by a Mechanism Dependent on MTF1
Obst, Jon K, Mawji, Nasrin R, Teskey, Simon J L, Wang, Jun, Sadar, Marianne D
Published in Cancers (13.01.2022)
Published in Cancers (13.01.2022)
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Journal Article
Niphatenones, Glycerol Ethers from the Sponge Niphates digitalis Block Androgen Receptor Transcriptional Activity in Prostate Cancer Cells: Structure Elucidation, Synthesis, and Biological Activity
Meimetis, Labros G, Williams, David E, Mawji, Nasrin R, Banuelos, Carmen A, Lal, Aaron A, Park, Jacob J, Tien, Amy H, Fernandez, Javier Garcia, de Voogd, Nicole J, Sadar, Marianne D, Andersen, Raymond J
Published in Journal of medicinal chemistry (12.01.2012)
Published in Journal of medicinal chemistry (12.01.2012)
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Journal Article
Characterization of niphatenones that inhibit androgen receptor N-terminal domain
Banuelos, Carmen A, Lal, Aaron, Tien, Amy H, Shah, Neel, Yang, Yu Chi, Mawji, Nasrin R, Meimetis, Labros G, Park, Jacob, Kunzhong, Jian, Andersen, Raymond J, Sadar, Marianne D
Published in PloS one (2014)
Published in PloS one (2014)
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Journal Article
Inhibition of androgen receptor by decoy molecules delays progression to castration-recurrent prostate cancer
Myung, Jae-Kyung, Wang, Gang, Chiu, Helen H L, Wang, Jun, Mawji, Nasrin R, Sadar, Marianne D
Published in PloS one (17.03.2017)
Published in PloS one (17.03.2017)
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Journal Article
Androgen receptor decoy molecules block the growth of prostate cancer
Quayle, Steven N, Mawji, Nasrin R, Wang, Jun, Sadar, Marianne D
Published in Proceedings of the National Academy of Sciences - PNAS (23.01.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (23.01.2007)
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Journal Article
Spongian diterpenoids inhibit androgen receptor activity
Yang, Yu Chi, Meimetis, Labros G, Tien, Amy H, Mawji, Nasrin R, Carr, Gavin, Wang, Jun, Andersen, Raymond J, Sadar, Marianne D
Published in Molecular cancer therapeutics (01.05.2013)
Published in Molecular cancer therapeutics (01.05.2013)
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Journal Article
An orthotopic metastatic prostate cancer model in SCID mice via grafting of a transplantable human prostate tumor line
YUWEI WANG, HUI XUE, GOUT, Peter W, SQUIRE, Jeremy A, CUNHA, Gerald R, WANG, Yu-Zhuo, CUTZ, Jean-Claude, BAYANI, Jane, MAWJI, Nasrin R, CHEN, Wilfred G, GOETZ, Lester J, HAYWARD, Simon W, SADAR, Marianne D, GILKS, C. Blake
Published in Laboratory investigation (01.11.2005)
Published in Laboratory investigation (01.11.2005)
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Journal Article
Targeting Androgen Receptor Activation Function-1 with EPI to Overcome Resistance Mechanisms in Castration-Resistant Prostate Cancer
Yang, Yu Chi, Banuelos, Carmen Adriana, Mawji, Nasrin R, Wang, Jun, Kato, Minoru, Haile, Simon, McEwan, Iain J, Plymate, Stephen, Sadar, Marianne D
Published in Clinical cancer research (01.09.2016)
Published in Clinical cancer research (01.09.2016)
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Journal Article
Structure–Activity Relationships for the Marine Natural Product Sintokamides: Androgen Receptor N‑Terminus Antagonists of Interest for Treatment of Metastatic Castration-Resistant Prostate Cancer
Yan, Luping, Banuelos, Carmen A, Mawji, Nasrin R, Patrick, Brian O, Sadar, Marianne D, Andersen, Raymond J
Published in Journal of natural products (Washington, D.C.) (26.03.2021)
Published in Journal of natural products (Washington, D.C.) (26.03.2021)
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Journal Article
Sintokamide A Is a Novel Antagonist of Androgen Receptor That Uniquely Binds Activation Function-1 in Its Amino-terminal Domain
Banuelos, Carmen A, Tavakoli, Iran, Tien, Amy H, Caley, Daniel P, Mawji, Nasrin R, Li, Zhenzhen, Wang, Jun, Yang, Yu Chi, Imamura, Yusuke, Yan, Luping, Wen, Jian Guo, Andersen, Raymond J, Sadar, Marianne D
Published in The Journal of biological chemistry (14.10.2016)
Published in The Journal of biological chemistry (14.10.2016)
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Journal Article
Osteoblast-Derived Factors Induce Androgen-Independent Proliferation and Expression of Prostate-Specific Antigen in Human Prostate Cancer Cells
BLASZCZYK, Natalie, MASRI, Bassam A, SADAR, Marianne D, MAWJI, Nasrin R, UEDA, Takeshi, MCALINDEN, Gavan, DUNCAN, Clive P, BRUCHOVSKY, Nicholas, SCHWEIKERT, Hans-Udo, SCHNABEL, Doris, JONES, Edward C
Published in Clinical cancer research (01.03.2004)
Published in Clinical cancer research (01.03.2004)
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Journal Article
Rational optimization of a transcription factor activation domain inhibitor
Basu, Shaon, Martínez-Cristóbal, Paula, Frigolé-Vivas, Marta, Pesarrodona, Mireia, Lewis, Michael, Szulc, Elzbieta, Bañuelos, C Adriana, Sánchez-Zarzalejo, Carolina, Bielskutė, Stasė, Zhu, Jiaqi, Pombo-García, Karina, Garcia-Cabau, Carla, Zodi, Levente, Dockx, Hannes, Smak, Jordann, Kaur, Harpreet, Batlle, Cristina, Mateos, Borja, Biesaga, Mateusz, Escobedo, Albert, Bardia, Lídia, Verdaguer, Xavier, Ruffoni, Alessandro, Mawji, Nasrin R, Wang, Jun, Obst, Jon K, Tam, Teresa, Brun-Heath, Isabelle, Ventura, Salvador, Meierhofer, David, García, Jesús, Robustelli, Paul, Stracker, Travis H, Sadar, Marianne D, Riera, Antoni, Hnisz, Denes, Salvatella, Xavier
Published in Nature structural & molecular biology (01.12.2023)
Published in Nature structural & molecular biology (01.12.2023)
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Journal Article
Sintokamides A to E, Chlorinated Peptides from the Sponge Dysidea sp. that Inhibit Transactivation of the N-Terminus of the Androgen Receptor in Prostate Cancer Cells
Sadar, Marianne D, Williams, David E, Mawji, Nasrin R, Patrick, Brian O, Wikanta, Thamrin, Chasanah, Ekowati, Irianto, Hari Eko, Soest, Rob Van, Andersen, Raymond J
Published in Organic letters (06.11.2008)
Published in Organic letters (06.11.2008)
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Journal Article
MP66-07 TARGETING ANDROGEN RECEPTOR N-TERMINAL DOMAIN FOR PROSTATE CANCER IMAGING AND THERAPY
Imamura, Yusuke, Tien, Amy H, Mawji, Nasrin R, Kun Zhong, Jian, Pan, Jinhe, Lin, Kuo-Shyan, Andersen, Raymond J, Sadar, Marianne D
Published in The Journal of urology (01.04.2015)
Published in The Journal of urology (01.04.2015)
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