A rationale for determining, testing, and controlling specific impurities in pharmaceuticals that possess potential for genotoxicity
Müller, Lutz, Mauthe, Robert J., Riley, Christopher M., Andino, Marta M., Antonis, David De, Beels, Chris, DeGeorge, Joseph, De Knaep, Alfons G.M., Ellison, Dean, Fagerland, Jane A., Frank, Rebecca, Fritschel, Betsy, Galloway, Sheila, Harpur, Ernie, Humfrey, Charles D.N., Jacks, Alexander S., Jagota, Nirdosh, Mackinnon, John, Mohan, Ganapathy, Ness, Daniel K., O’Donovan, Michael R., Smith, Mark D., Vudathala, Gopi, Yotti, Larry
Published in Regulatory toxicology and pharmacology (01.04.2006)
Published in Regulatory toxicology and pharmacology (01.04.2006)
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Journal Article
Comparative biotransformation studies of MeIQx and PhIP in animal models and humans
Garner, R.C, Lightfoot, T.J, Cupid, B.C, Russell, D, Coxhead, J.M, Kutschera, W, Priller, A, Rom, W, Steier, P, Alexander, D.J, Leveson, S.H, Dingley, K.H, Mauthe, R.J, Turteltaub, K.W
Published in Cancer letters (01.09.1999)
Published in Cancer letters (01.09.1999)
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Journal Article
Conference Proceeding
Quantitative imaging microscopy for the sensitive detection of administered metal containing drugs in single cells and tissue slices—a demonstration using platinum based chemotherapeutic agents
Mauthe, R.J, Sideras-Haddad, E, Turteltaub, K.W, Bench, G
Published in Journal of pharmaceutical and biomedical analysis (01.08.1998)
Published in Journal of pharmaceutical and biomedical analysis (01.08.1998)
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Journal Article
Investigation of the formation and accumulation of liver DNA adducts in mice chronically exposed to tamoxifen
MARTIN, E. A, CARTHEW, P, WHITE, I. N. H, HEYDON, R. T, GASKELL, M, MAUTHE, R. J, TURTELTAUB, K. W, SMITH, L. L
Published in Carcinogenesis (New York) (01.11.1997)
Published in Carcinogenesis (New York) (01.11.1997)
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Journal Article
Pyrethroid Decrease in Central Nervous System from Nerve Agent Pretreatment
Buchholz, Bruce A., Pawley, Norma H., Vogel, John S., Mauthe, Robert J.
Published in Journal of applied toxicology (01.07.1997)
Published in Journal of applied toxicology (01.07.1997)
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Journal Article
Comparison of DNA‐adduct and tissue‐available dose levels of MeIQx in human and rodent colon following administration of a very low dose
Mauthe, Robert J., Dingley, Karen H., Leveson, Steven H., Freeman, Stewart P.H.T., Turesky, Robert J., Garner, R. Colin, Turteltaub, Kenneth W.
Published in International journal of cancer (09.02.1999)
Published in International journal of cancer (09.02.1999)
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Journal Article
Interspecies differences in the major DNA adducts formed from benzo(a)pyrene but not 7,12-dimethylbenz(a)anthracene in rat and human mammary cell cultures
MOORE, C. J, PRUESS-SCHWARTZ, D, MAUTHE, R. J, GOULD, M. N, BAIRD, W. M
Published in Cancer research (Chicago, Ill.) (15.08.1987)
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Published in Cancer research (Chicago, Ill.) (15.08.1987)
Journal Article
MeIQx-DNA adduct formation in rodent and human tissues at low doses
Turteltaub, K W, Mauthe, R J, Dingley, K H, Vogel, J S, Frantz, C E, Garner, R C, Shen, N
Published in Mutation research (12.05.1997)
Published in Mutation research (12.05.1997)
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Journal Article
Comparisons of the binding of [ 14C]radiolabelled tamoxifen or toremifene to rat DNA using accelerator mass spectrometry
White, Ian N.H, Martin, Elizabeth A, Mauthe, Robert J, Vogel, John S, Turteltaub, Kenneth W, Smith, Lewis L
Published in Chemico-biological interactions (12.09.1997)
Published in Chemico-biological interactions (12.09.1997)
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Journal Article
SFTG international collaborative study on in vitro micronucleus test III. Using CHO cells
Aardema, Marilyn J, Snyder, Ronald D, Spicer, Carol, Divi, Katyayini, Morita, Takeshi, Mauthe, Robert J, Gibson, David P, Soelter, Sandra, Curry, Patrick T, Thybaud, Veronique, Lorenzon, Giocondo, Marzin, Daniel, Lorge, Elisabeth
Published in Mutation research (04.08.2006)
Published in Mutation research (04.08.2006)
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Journal Article
Context is key—Case studies on the biological significance and role of DNA adduct data in cancer risk assessment
Boogaard, P.J., Bachman, A., Martin, E., Mauthe, R.J., Pottenger, L.H., Schoeny, R., Skare, J.A., Kim, J.
Published in Toxicology letters (01.08.2011)
Published in Toxicology letters (01.08.2011)
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Journal Article
Quantitative imaging microscopy for the sensitive detection of administered metal containing drugs in single cells and tissue slices--a demonstration using platinum based chemotherapeutic agent
Mauthe, R J, Sideras-Haddad, E, Turteltaub, K W, Bench, G
Published in Journal of pharmaceutical and biomedical analysis (01.08.1998)
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Published in Journal of pharmaceutical and biomedical analysis (01.08.1998)
Journal Article
Quantitation of benzo[ a]pyrene-DNA adducts by postlabeling with 14C-acetic anhydride and accelerator mass spectrometry
Goldman, Radoslav, Day, Billy W, Carver, Tonya A, Mauthe, Robert J, Turteltaub, Kenneth W, Shields, Peter G
Published in Chemico-biological interactions (01.06.2000)
Published in Chemico-biological interactions (01.06.2000)
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