Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
Maurer, Till, Garrenton, Lindsay S, Oh, Angela, Pitts, Keith, Anderson, Daniel J, Skelton, Nicholas J, Fauber, Benjamin P, Pan, Borlan, Malek, Shiva, Stokoe, David, Ludlam, Mary J. C, Bowman, Krista K, Wu, Jiansheng, Giannetti, Anthony M, Starovasnik, Melissa A, Mellman, Ira, Jackson, Peter K, Rudolph, Joachim, Wang, Weiru, Fang, Guowei
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2012)
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Journal Article
Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes
Hewings, David S., Heideker, Johanna, Ma, Taylur P., AhYoung, Andrew P., El Oualid, Farid, Amore, Alessia, Costakes, Gregory T., Kirchhofer, Daniel, Brasher, Bradley, Pillow, Thomas, Popovych, Nataliya, Maurer, Till, Schwerdtfeger, Carsten, Forrest, William F., Yu, Kebing, Flygare, John, Bogyo, Matthew, Wertz, Ingrid E.
Published in Nature communications (21.03.2018)
Published in Nature communications (21.03.2018)
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Journal Article
Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation
Rougé, Lionel, Bainbridge, Travis W., Kwok, Michael, Tong, Raymond, Di Lello, Paola, Wertz, Ingrid E., Maurer, Till, Ernst, James A., Murray, Jeremy
Published in Structure (London) (02.08.2016)
Published in Structure (London) (02.08.2016)
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Journal Article
Backbone cyclization of a recombinant cystine-knot peptide by engineered Sortase A
Stanger, Karen, Maurer, Till, Kaluarachchi, Harini, Coons, Mary, Franke, Yvonne, Hannoush, Rami N.
Published in FEBS letters (28.11.2014)
Published in FEBS letters (28.11.2014)
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Journal Article
High-Resolution Structure of the Histidine-Containing Phosphocarrier Protein (HPr) from Staphylococcus aureus and Characterization of Its Interaction with the Bifunctional HPr Kinase/Phosphorylase
MAURER, Till, MEIER, Sebastian, KACHEL, Norman, MUNTE, Claudia Elisabeth, HASENBEIN, Sonja, KOCH, Brigitte, HENGSTENBERG, Wolfgang, KALBITZER, Hans Robert
Published in Journal of Bacteriology (01.09.2004)
Published in Journal of Bacteriology (01.09.2004)
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Journal Article
USP7 small-molecule inhibitors interfere with ubiquitin binding
Kategaya, Lorna, Di Lello, Paola, Rougé, Lionel, Pastor, Richard, Clark, Kevin R., Drummond, Jason, Kleinheinz, Tracy, Lin, Eva, Upton, John-Paul, Prakash, Sumit, Heideker, Johanna, McCleland, Mark, Ritorto, Maria Stella, Alessi, Dario R., Trost, Matthias, Bainbridge, Travis W., Kwok, Michael C. M., Ma, Taylur P., Stiffler, Zachary, Brasher, Bradley, Tang, Yinyan, Jaishankar, Priyadarshini, Hearn, Brian R., Renslo, Adam R., Arkin, Michelle R., Cohen, Frederick, Yu, Kebing, Peale, Frank, Gnad, Florian, Chang, Matthew T., Klijn, Christiaan, Blackwood, Elizabeth, Martin, Scott E., Forrest, William F., Ernst, James A., Ndubaku, Chudi, Wang, Xiaojing, Beresini, Maureen H., Tsui, Vickie, Schwerdtfeger, Carsten, Blake, Robert A., Murray, Jeremy, Maurer, Till, Wertz, Ingrid E.
Published in Nature (London) (26.10.2017)
Published in Nature (London) (26.10.2017)
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Journal Article
Structure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin
Ultsch, Mark, Li, Bing, Maurer, Till, Mathieu, Mary, Adolfsson, Oskar, Muhs, Andreas, Pfeifer, Andrea, Pihlgren, Maria, Bainbridge, Travis W., Reichelt, Mike, Ernst, James A., Eigenbrot, Charles, Fuh, Germaine, Atwal, Jasvinder K., Watts, Ryan J., Wang, Weiru
Published in Scientific reports (20.12.2016)
Published in Scientific reports (20.12.2016)
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Journal Article
Discovery of Small-Molecule Inhibitors of Ubiquitin Specific Protease 7 (USP7) Using Integrated NMR and in Silico Techniques
Di Lello, Paola, Pastor, Richard, Murray, Jeremy M, Blake, Robert A, Cohen, Frederick, Crawford, Terry D, Drobnick, Joy, Drummond, Jason, Kategaya, Lorna, Kleinheinz, Tracy, Maurer, Till, Rougé, Lionel, Zhao, Xianrui, Wertz, Ingrid, Ndubaku, Chudi, Tsui, Vickie
Published in Journal of medicinal chemistry (28.12.2017)
Published in Journal of medicinal chemistry (28.12.2017)
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Journal Article
Structural basis for dual-mode inhibition of the ABC transporter MsbA
Ho, Hoangdung, Miu, Anh, Alexander, Mary Kate, Garcia, Natalie K., Oh, Angela, Zilberleyb, Inna, Reichelt, Mike, Austin, Cary D., Tam, Christine, Shriver, Stephanie, Hu, Huiyong, Labadie, Sharada S., Liang, Jun, Wang, Lan, Wang, Jian, Lu, Yan, Purkey, Hans E., Quinn, John, Franke, Yvonne, Clark, Kevin, Beresini, Maureen H., Tan, Man-Wah, Sellers, Benjamin D., Maurer, Till, Koehler, Michael F. T., Wecksler, Aaron T., Kiefer, James R., Verma, Vishal, Xu, Yiming, Nishiyama, Mireille, Payandeh, Jian, Koth, Christopher M.
Published in Nature (London) (01.05.2018)
Published in Nature (London) (01.05.2018)
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Journal Article
Solution Structure of Leukemia Inhibitory Factor
Hinds, Mark G., Maurer, Till, Zhang, Jian-Guo, Nicola, Nicos A., Norton, Raymond S.
Published in The Journal of biological chemistry (29.05.1998)
Published in The Journal of biological chemistry (29.05.1998)
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Journal Article
Combined chemical shift changes and amino acid specific chemical shift mapping of protein-protein interactions
Schumann, Frank H, Riepl, Hubert, Maurer, Till, Gronwald, Wolfram, Neidig, Klaus-Peter, Kalbitzer, Hans Robert
Published in Journal of biomolecular NMR (01.12.2007)
Published in Journal of biomolecular NMR (01.12.2007)
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Journal Article
De Novo Guanine Biosynthesis but Not the Riboswitch-Regulated Purine Salvage Pathway Is Required for Staphylococcus aureus Infection In Vivo
Kofoed, Eric M, Yan, Donghong, Katakam, Anand K, Reichelt, Mike, Lin, Baiwei, Kim, Janice, Park, Summer, Date, Shailesh V, Monk, Ian R, Xu, Min, Austin, Cary D, Maurer, Till, Tan, Man-Wah
Published in Journal of bacteriology (15.07.2016)
Published in Journal of bacteriology (15.07.2016)
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Journal Article
Phosphorylation-dependent activity of the deubiquitinase DUBA
Huang, Oscar W, Ma, Xiaolei, Yin, JianPing, Flinders, Jeremy, Maurer, Till, Kayagaki, Nobuhiko, Phung, Qui, Bosanac, Ivan, Arnott, David, Dixit, Vishva M, Hymowitz, Sarah G, Starovasnik, Melissa A, Cochran, Andrea G
Published in Nature structural & molecular biology (01.02.2012)
Published in Nature structural & molecular biology (01.02.2012)
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Journal Article
Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation
Rougé, Lionel, Bainbridge, Travis W., Kwok, Michael, Tong, Raymond, Di Lello, Paola, Wertz, Ingrid E., Maurer, Till, Ernst, James A., Murray, Jeremy
Published in Structure (London) (01.08.2016)
Published in Structure (London) (01.08.2016)
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Journal Article