Septin 9 induces lipid droplets growth by a phosphatidylinositol-5-phosphate and microtubule-dependent mechanism hijacked by HCV
Akil, Abdellah, Peng, Juan, Omrane, Mohyeddine, Gondeau, Claire, Desterke, Christophe, Marin, Mickaël, Tronchère, Hélène, Taveneau, Cyntia, Sar, Sokhavuth, Briolotti, Philippe, Benjelloun, Soumaya, Benjouad, Abdelaziz, Maurel, Patrick, Thiers, Valérie, Bressanelli, Stéphane, Samuel, Didier, Bréchot, Christian, Gassama-Diagne, Ama
Published in Nature communications (15.07.2016)
Published in Nature communications (15.07.2016)
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The low-density lipoprotein receptor plays a role in the infection of primary human hepatocytes by hepatitis C virus
Molina, Sonia, Castet, Valérie, Fournier-Wirth, Chantal, Pichard-Garcia, Lydiane, Avner, Rachel, Harats, Dror, Roitelman, Joseph, Barbaras, Ronald, Graber, Pierre, Ghersa, Paola, Smolarsky, Moshe, Funaro, Ada, Malavasi, Fabio, Larrey, Dominique, Coste, Joliette, Fabre, Jean-Michel, Sa-Cunha, Antonio, Maurel, Patrick
Published in Journal of hepatology (01.03.2007)
Published in Journal of hepatology (01.03.2007)
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Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies
Hewitt, Nicola J., Gómez Lechón, María José, Houston, J. Brian, Hallifax, David, Brown, Hayley S., Maurel, Patrick, Kenna, J. Gerald, Gustavsson, Lena, Lohmann, Christina, Skonberg, Christian, Guillouzo, Andre, Tuschl, Gregor, Li, Albert P., LeCluyse, Edward, Groothuis, Geny M. M., Hengstler, Jan G.
Published in Drug metabolism reviews (2007)
Published in Drug metabolism reviews (2007)
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Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
Schuetz, Erin, Kuehl, Peter, Zhang, Jiong, Lin, Yvonne, Lamba, Jatinder, Assem, Mahfoud, Schuetz, John, Watkins, Paul B, Daly, Ann, Wrighton, Steven A, Hall, Stephen D, Maurel, Patrick, Relling, Mary, Brimer, Cynthia, Yasuda, Kazuto, Venkataramanan, Raman, Strom, Stephen, Thummel, Kenneth, Boguski, Mark S
Published in Nature genetics (01.04.2001)
Published in Nature genetics (01.04.2001)
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Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes
Vrzal, Radim, Stejskalova, Lucie, Monostory, Katalin, Maurel, Patrick, Bachleda, Petr, Pavek, Petr, Dvorak, Zdenek
Published in Chemico-biological interactions (15.05.2009)
Published in Chemico-biological interactions (15.05.2009)
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Hepatitis C virus infection reduces hepatocellular polarity in a vascular endothelial growth factor-dependent manner
Mee, Christopher J, Farquhar, Michelle J, Harris, Helen J, Hu, Ke, Ramma, Wenda, Ahmed, Asif, Maurel, Patrick, Bicknell, Roy, Balfe, Peter, McKeating, Jane A
Published in Gastroenterology (New York, N.Y. 1943) (01.03.2010)
Published in Gastroenterology (New York, N.Y. 1943) (01.03.2010)
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Modular bioreactor for primary human hepatocyte culture: Medium flow stimulates expression and activity of detoxification genes
Vinci, Bruna, Duret, Cédric, Klieber, Sylvie, Gerbal‐Chaloin, Sabine, Sa‐Cunha, Antonio, Laporte, Sylvain, Suc, Bertrand, Maurel, Patrick, Ahluwalia, Arti, Daujat‐Chavanieu, Martine
Published in Biotechnology journal (01.05.2011)
Published in Biotechnology journal (01.05.2011)
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Serum-Derived Hepatitis C Virus Infection of Primary Human Hepatocytes Is Tetraspanin CD81 Dependent
MOLINA, Sonia, CASTET, Valerie, DUBUISSON, Jean, COSTE, Joliette, MCKEATING, Jane, MAUREL, Patrick, FOURNIER-WIRTH, Chantal, PICHARD-GARCIA, Lydiane, WYCHOWSKI, Czeslaw, MEURS, Eliane, PASCUSSI, Jean-Marc, SUREAU, Camille, FABRE, Jean-Michel, SACUNHA, Antonio, LARREY, Dominique
Published in Journal of Virology (01.01.2008)
Published in Journal of Virology (01.01.2008)
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In vitro infection of primary human hepatocytes by HCV-positive sera: insights on a highly relevant model
Gondeau, Claire, Briolotti, Philippe, Razafy, Francia, Duret, Cédric, Rubbo, Pierre-Alain, Helle, François, Rème, Thierry, Ripault, Marie-Pierre, Ducos, Jacques, Fabre, Jean-Michel, Ramos, Jeanne, Pécheur, Eve-Isabelle, Larrey, Dominique, Maurel, Patrick, Daujat-Chavanieu, Martine
Published in Gut (01.09.2014)
Published in Gut (01.09.2014)
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Zearalenone activates pregnane X receptor, constitutive androstane receptor and aryl hydrocarbon receptor and corresponding phase I target genes mRNA in primary cultures of human hepatocytes
Ayed-Boussema, Imen, Pascussi, Jean Marc, Maurel, Patrick, Bacha, Hassen, Hassen, Wafa
Published in Environmental toxicology and pharmacology (01.01.2011)
Published in Environmental toxicology and pharmacology (01.01.2011)
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Journal Article
Protein Kinase A-Dependent Step(s) in Hepatitis C Virus Entry and Infectivity
FARQUHAR, Michelle J, HARRIS, Helen J, HOWL, John, HERBERG, Friedrich W, VAN IJZENDOORN, Sven C. D, BALFE, Peter, MCKEATING, Jane A, DISKAR, Mandy, JONES, Sarah, MEE, Christopher J, NIELSEN, Søren U, BRIMACOMBE, Claire L, MOLINA, Sonia, TOMS, Geoffrey L, MAUREL, Patrick
Published in Journal of Virology (01.09.2008)
Published in Journal of Virology (01.09.2008)
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Cold Preservation of Human Adult Hepatocytes for Liver Cell Therapy
Duret, Cedric, Moreno, Daniel, Balasiddaiah, Anangi, Roux, Solene, Briolotti, Phillipe, Raulet, Edith, Herrero, Astrid, Ramet, Helene, Biron-Andreani, Christine, Gerbal-Chaloin, Sabine, Ramos, Jeanne, Navarro, Francis, Hardwigsen, Jean, Maurel, Patrick, Aldabe, Rafael, Daujat-Chavanieu, Martine
Published in Cell transplantation (01.12.2015)
Published in Cell transplantation (01.12.2015)
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Systemic delivery of siRNA down regulates brain prion protein and ameliorates neuropathology in prion disorder
Lehmann, Sylvain, Relano-Gines, Aroa, Resina, Sarah, Brillaud, Elsa, Casanova, Danielle, Vincent, Charles, Hamela, Claire, Poupeau, Sophie, Laffont, Mathieu, Gabelle, Audrey, Delaby, Constance, Belondrade, Maxime, Arnaud, Jacques-Damien, Alvarez, Maria-Teresa, Maurel, Jean-Claude, Maurel, Patrick, Crozet, Carole
Published in PloS one (14.02.2014)
Published in PloS one (14.02.2014)
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The Circadian Clock Components CRY1 and CRY2 Are Necessary to Sustain Sex Dimorphism in Mouse Liver Metabolism
Bur, Isabelle M., Cohen-Solal, Anne M., Carmignac, Danielle, Abecassis, Pierre-Yves, Chauvet, Norbert, Martin, Agnès O., van der Horst, Gijsbertus T.J., Robinson, Iain C.A.F., Maurel, Patrick, Mollard, Patrice, Bonnefont, Xavier
Published in The Journal of biological chemistry (03.04.2009)
Published in The Journal of biological chemistry (03.04.2009)
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Journal Article
JNK inhibitor SP600125 is a partial agonist of human aryl hydrocarbon receptor and induces CYP1A1 and CYP1A2 genes in primary human hepatocytes
Dvorak, Zdenek, Vrzal, Radim, Henklova, Pavla, Jancova, Petra, Anzenbacherova, Eva, Maurel, Patrick, Svecova, Lucie, Pavek, Petr, Ehrmann, Jiri, Havlik, Roman, Bednar, Petr, Lemr, Karel, Ulrichova, Jitka
Published in Biochemical pharmacology (15.01.2008)
Published in Biochemical pharmacology (15.01.2008)
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SB203580, a pharmacological inhibitor of p38 MAP kinase transduction pathway activates ERK and JNK MAP kinases in primary cultures of human hepatocytes
Henklova, Pavla, Vrzal, Radim, Papouskova, Barbora, Bednar, Petr, Jancova, Petra, Anzenbacherova, Eva, Ulrichova, Jitka, Maurel, Patrick, Pavek, Petr, Dvorak, Zdenek
Published in European journal of pharmacology (28.09.2008)
Published in European journal of pharmacology (28.09.2008)
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Isolation, Characterization, and Differentiation to Hepatocyte‐Like Cells of Nonparenchymal Epithelial Cells from Adult Human Liver
Duret, Cédric, Gerbal‐Chaloin, Sabine, Ramos, Jeanne, Fabre, Jean‐Michel, Jacquet, Eric, Navarro, Francis, Blanc, Pierre, Sa‐Cunha, Antonio, Maurel, Patrick, Daujat‐Chavanieu, Martine
Published in Stem cells (Dayton, Ohio) (01.07.2007)
Published in Stem cells (Dayton, Ohio) (01.07.2007)
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Hepatic Expression of Thyroid Hormone-Responsive Spot 14 Protein Is Regulated by Constitutive Androstane Receptor (NR1I3)
Breuker, Cyril, Moreau, Amélie, Lakhal, Laila, Tamasi, Viola, Parmentier, Yannick, Meyer, Urs, Maurel, Patrick, Lumbroso, Serge, Vilarem, Marie-José, Pascussi, Jean-Marc
Published in Endocrinology (Philadelphia) (01.04.2010)
Published in Endocrinology (Philadelphia) (01.04.2010)
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