Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity
Leger, Paul R, Hu, Dennis X, Biannic, Berenger, Bui, Minna, Han, Xinping, Karbarz, Emily, Maung, Jack, Okano, Akinori, Osipov, Maksim, Shibuya, Grant M, Young, Kyle, Higgs, Christopher, Abraham, Betty, Bradford, Delia, Cho, Cynthia, Colas, Christophe, Jacobson, Scott, Ohol, Yamini M, Pookot, Deepa, Rana, Payal, Sanchez, Jerick, Shah, Niket, Sun, Michael, Wong, Steve, Brockstedt, Dirk G, Kassner, Paul D, Schwarz, Jacob B, Wustrow, David J
Published in Journal of medicinal chemistry (28.05.2020)
Published in Journal of medicinal chemistry (28.05.2020)
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Novel, Selective Inhibitors of USP7 Uncover Multiple Mechanisms of Antitumor Activity In Vitro and In Vivo
Ohol, Yamini M., Sun, Michael T., Cutler, Gene, Leger, Paul R., Hu, Dennis X., Biannic, Berenger, Rana, Payal, Cho, Cynthia, Jacobson, Scott, Wong, Steve T., Sanchez, Jerick, Shah, Niket, Pookot, Deepa, Abraham, Betty, Young, Kyle, Suthram, Silpa, Marshall, Lisa A., Bradford, Delia, Kozon, Nathan, Han, Xinping, Okano, Akinori, Maung, Jack, Colas, Christophe, Schwarz, Jacob, Wustrow, David, Brockstedt, Dirk G., Kassner, Paul D.
Published in Molecular cancer therapeutics (01.10.2020)
Published in Molecular cancer therapeutics (01.10.2020)
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Potent GCN2 Inhibitor Capable of Reversing MDSC-Driven T Cell Suppression Demonstrates In Vivo Efficacy as a Single Agent and in Combination with Anti-Angiogenesis Therapy
Jackson, Jeffrey J., Shibuya, Grant M., Ravishankar, Buvana, Adusumilli, Lavanya, Bradford, Delia, Brockstedt, Dirk G., Bucher, Cyril, Bui, Minna, Cho, Cynthia, Colas, Christoph, Cutler, Gene, Dukes, Adrian, Han, Xinping, Hu, Dennis X., Jacobson, Scott, Kassner, Paul D., Katibah, George E., Ko, Michelle Yoo Min, Kolhatkar, Urvi, Leger, Paul R., Ma, Anqi, Marshall, Lisa, Maung, Jack, Ng, Andrew A., Okano, Akinori, Pookot, Deepa, Poon, Daniel, Ramana, Chandru, Reilly, Maureen K., Robles, Omar, Schwarz, Jacob B., Shakhmin, Anton A., Shunatona, Hunter P., Sreenivasan, Raashi, Tivitmahaisoon, Parcharee, Xu, Mengshu, Zaw, Thant, Wustrow, David J., Zibinsky, Mikhail
Published in Journal of medicinal chemistry (13.10.2022)
Published in Journal of medicinal chemistry (13.10.2022)
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Abstract 4441: Discovery of potent and selective inhibitors of USP7 with anti-tumor activity in vitro and in vivo
Ohol, Yamini M., Sun, Michael, Leger, Paul, Hu, Dennis, Biannic, Berenger, Rana, Payal, Cho, Cynthia, Jacobson, Scott, Wong, Steve, Sanchez, Jerick, Han, Xinping, Young, Kyle, Okano, Akinori, Maung, Jack, Cutler, Gene, Shah, Nick, Adusumilli, Lavanya, Kaveri, Deepika, Talay, Oezcan, Pookot, Deepa, Abraham, Betty, Bradford, Delia, Kozon, Nathan, Colas, Christophe, Kim, Andrea, Schwarz, Jacob, Wustrow, David, Brockstedt, Dirk, Kassner, Paul
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 2915: Discovery and optimization of potent and selective inhibitors of USP7 to enhance anti-tumor immunity and target tumor growth
Abraham, Betty, Adusumilli, Lavanya, Biannic, Berenger, Bradford, Delia, Brovarney, Martin, Chian, David, Cutler, Gene, Han, Xinping, Hu, Dennis, Jacobson, Scott, Johnson, Sherra, Kassner, Paul, Kaveri, Deepika, Ketcham, John, Kim, Andrea, Leger, Paul, Marshall, Lisa, Marubayashi, Sachie, Maung, Jack, McKinnell, Jenny, Meleza, Cesar, Ohol, Yamini, Okano, Akinori, Peiser, Leanne, Pookot, Deepa, Rana, Payal, Schwarz, Jacob, Shah, Nick, Shibuya, Grant, Sun, Michael, Suthram, Silpa, Talay, Oezcan, Wadsworth, Angela, Wustrow, David, Young, Kyle, Napper, Andrew
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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The molecular pruning of a phosphoramidate peptidomimetic inhibitor of prostate-specific membrane antigen
Wu, Lisa Y., Anderson, Marc O., Toriyabe, Yoko, Maung, Jack, Campbell, Tammy Y., Tajon, Cheryl, Kazak, Marat, Moser, Jamie, Berkman, Clifford E.
Published in Bioorganic & medicinal chemistry (01.12.2007)
Published in Bioorganic & medicinal chemistry (01.12.2007)
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Imidazo[1,2-a]pyridines That Directly Interact with Hepatitis C NS4B: Initial Preclinical Characterization
Shotwell, J. Brad, Baskaran, Subramanian, Chong, Pek, Creech, Katrina L, Crosby, Renae M, Dickson, Hamilton, Fang, Jing, Garrido, Dulce, Mathis, Amanda, Maung, Jack, Parks, Derek J, Pouliot, Jeffrey J, Price, Daniel J, Rai, Roopa, Seal, John W, Schmitz, Uli, Tai, Vincent W. F, Thomson, Michael, Xie, Mi, Xiong, Zhiping Z, Peat, Andrew J
Published in ACS medicinal chemistry letters (12.07.2012)
Published in ACS medicinal chemistry letters (12.07.2012)
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피라졸 화합물 및 이러한 화합물을 제조하고 사용하는 방법
LI HUI, KELLEY RYAN, SINGH RAJINDER, HECKRODT THILO, CHEN YAN, TAYLOR VANESSA, MAUNG JACK, YEN ROSE, MCMURTRIE DARREN, TSO KIN
Year of Publication 15.12.2017
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Year of Publication 15.12.2017
Patent
Probing for a hydrophobic a binding register in prostate-specific membrane antigen with phenylalkylphosphonamidates
Maung, Jack, Mallari, Jeremy P., Girtsman, Teri A., Wu, Lisa Y., Rowley, Jennifer A., Santiago, Nicholas M., Brunelle, Alan N., Berkman, Clifford E.
Published in Bioorganic & medicinal chemistry (15.09.2004)
Published in Bioorganic & medicinal chemistry (15.09.2004)
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Water-soluble prodrugs of an Aurora kinase inhibitor
Oslob, Johan D., Heumann, Stacey A., Yu, Chul H., Allen, Darin A., Baskaran, Subramanian, Bui, Minna, Delarosa, Erlie, Fung, Amy D., Hashash, Ahmad, Hau, Jonathan, Ivy, Sheryl, Jacobs, Jeffrey W., Lew, Willard, Maung, Jack, McDowell, Robert S., Ritchie, Sean, Romanowski, Michael J., Silverman, Jeffrey A., Yang, Wenjin, Zhong, Min, Fuchs-Knotts, Tarra
Published in Bioorganic & medicinal chemistry letters (01.03.2009)
Published in Bioorganic & medicinal chemistry letters (01.03.2009)
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