HILPDA Uncouples Lipid Droplet Accumulation in Adipose Tissue Macrophages from Inflammation and Metabolic Dysregulation
van Dierendonck, Xanthe A.M.H., de la Rosa Rodriguez, Montserrat A., Georgiadi, Anastasia, Mattijssen, Frits, Dijk, Wieneke, van Weeghel, Michel, Singh, Rajat, Borst, Jan Willem, Stienstra, Rinke, Kersten, Sander
Published in Cell reports (Cambridge) (11.02.2020)
Published in Cell reports (Cambridge) (11.02.2020)
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The glucocorticoid receptor in brown adipocytes is dispensable for control of energy homeostasis
Glantschnig, Christina, Mattijssen, Frits, Vogl, Elena Sophie, Ali Khan, Asrar, Rios Garcia, Marcos, Fischer, Katrin, Müller, Timo, Uhlenhaut, Henriette, Nawroth, Peter, Scheideler, Marcel, Rose, Adam J, Pellegata, Natalia, Herzig, Stephan
Published in EMBO reports (05.11.2019)
Published in EMBO reports (05.11.2019)
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Fatty acid-inducible ANGPTL4 governs lipid metabolic response to exercise
Catoire, Milène, Alex, Sheril, Paraskevopulos, Nicolas, Mattijssen, Frits, Gogh, Inkie Evers-van, Schaart, Gert, Jeppesen, Jacob, Kneppers, Anita, Mensink, Marco, Voshol, Peter J., Olivecrona, Gunilla, Tan, Nguan Soon, Hesselink, Matthijs K. C., Berbée, Jimmy F., Rensen, Patrick C. N., Kalkhoven, Eric, Schrauwen, Patrick, Kersten, Sander
Published in Proceedings of the National Academy of Sciences - PNAS (18.03.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (18.03.2014)
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Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels
BOSMA, Madeleen, HESSELINK, Matthijs K. C, KERSTEN, Sander, SCHRAUWEN, Patrick, SPARKS, Lauren M, TIMMERS, Silvie, FERRAZ, Maria Joao, MATTIJSSEN, Frits, BEURDEN, Denis Van, SCHAART, Gert, DE BAETS, Marc H, VERHEYEN, Fons K
Published in Diabetes (New York, N.Y.) (01.11.2012)
Published in Diabetes (New York, N.Y.) (01.11.2012)
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The ER-Associated Degradation Adaptor Protein Sel1L Regulates LPL Secretion and Lipid Metabolism
Sha, Haibo, Sun, Shengyi, Francisco, Adam B., Ehrhardt, Nicole, Xue, Zhen, Liu, Lei, Lawrence, Peter, Mattijssen, Frits, Guber, Robert D., Panhwar, Muhammad S., Brenna, J. Thomas, Shi, Hang, Xue, Bingzhong, Kersten, Sander, Bensadoun, André, Péterfy, Miklós, Long, Qiaoming, Qi, Ling
Published in Cell metabolism (02.09.2014)
Published in Cell metabolism (02.09.2014)
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HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling
Giroud, Maude, Tsokanos, Foivos-Filippos, Caratti, Giorgio, Kotschi, Stefan, Khani, Sajjad, Jouffe, Céline, Vogl, Elena S., Irmler, Martin, Glantschnig, Christina, Gil-Lozano, Manuel, Hass, Daniela, Khan, Asrar Ali, Garcia, Marcos Rios, Mattijssen, Frits, Maida, Adriano, Tews, Daniel, Fischer-Posovszky, Pamela, Feuchtinger, Annette, Virtanen, Kirsi A., Beckers, Johannes, Wabitsch, Martin, Uhlenhaut, Henriette, Blüher, Matthias, Tuckermann, Jan, Scheideler, Marcel, Bartelt, Alexander, Herzig, Stephan
Published in Diabetologia (01.08.2021)
Published in Diabetologia (01.08.2021)
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Hypoxia-inducible Lipid Droplet-associated (HILPDA) Is a Novel Peroxisome Proliferator-activated Receptor (PPAR) Target Involved in Hepatic Triglyceride Secretion
Mattijssen, Frits, Georgiadi, Anastasia, Andasarie, Tresty, Szalowska, Ewa, Zota, Annika, Krones-Herzig, Anja, Heier, Christoph, Ratman, Dariusz, De Bosscher, Karolien, Qi, Ling, Zechner, Rudolf, Herzig, Stephan, Kersten, Sander
Published in The Journal of biological chemistry (11.07.2014)
Published in The Journal of biological chemistry (11.07.2014)
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Trip13 Depletion in Liver Cancer Induces a Lipogenic Response Contributing to Plin2‐Dependent Mitotic Cell Death
Rios Garcia, Marcos, Meissburger, Bettina, Chan, Jessica, Guia, Roldan M., Mattijssen, Frits, Roessler, Stephanie, Birkenfeld, Andreas L., Raschzok, Nathanael, Riols, Fabien, Tokarz, Janina, Giroud, Maude, Gil Lozano, Manuel, Hartleben, Goetz, Nawroth, Peter, Haid, Mark, López, Miguel, Herzig, Stephan, Berriel Diaz, Mauricio
Published in Advanced science (01.10.2022)
Published in Advanced science (01.10.2022)
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Linking nutritional regulation of Angptl4, Gpihbp1, and Lmf1 to lipoprotein lipase activity in rodent adipose tissue
Kroupa, Olessia, Vorrsjö, Evelina, Stienstra, Rinke, Mattijssen, Frits, Nilsson, Stefan K, Sukonina, Valentina, Kersten, Sander, Olivecrona, Gunilla, Olivecrona, Thomas
Published in BMC physiology (23.11.2012)
Published in BMC physiology (23.11.2012)
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A Hepatic GAbp-AMPK Axis Links Inflammatory Signaling to Systemic Vascular Damage
Niopek, Katharina, Üstünel, Bilgen Ekim, Seitz, Susanne, Sakurai, Minako, Zota, Annika, Mattijssen, Frits, Wang, Xiaoyue, Sijmonsma, Tjeerd, Feuchter, Yvonne, Gail, Anna M., Leuchs, Barbara, Niopek, Dominik, Staufer, Oskar, Brune, Maik, Sticht, Carsten, Gretz, Norbert, Müller-Decker, Karin, Hammes, Hans-Peter, Nawroth, Peter, Fleming, Thomas, Conkright, Michael D., Blüher, Matthias, Zeigerer, Anja, Herzig, Stephan, Berriel Diaz, Mauricio
Published in Cell reports (Cambridge) (08.08.2017)
Published in Cell reports (Cambridge) (08.08.2017)
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Journal Article
Angptl4 Protects against Severe Proinflammatory Effects of Saturated Fat by Inhibiting Fatty Acid Uptake into Mesenteric Lymph Node Macrophages
Lichtenstein, Laeticia, Mattijssen, Frits, de Wit, Nicole J., Georgiadi, Anastasia, Hooiveld, Guido J., van der Meer, Roelof, He, Yin, Qi, Ling, Köster, Anja, Tamsma, Jouke T., Tan, Nguan Soon, Müller, Michael, Kersten, Sander
Published in Cell metabolism (01.12.2010)
Published in Cell metabolism (01.12.2010)
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Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence
Rios Garcia, Marcos, Steinbauer, Brigitte, Srivastava, Kshitij, Singhal, Mahak, Mattijssen, Frits, Maida, Adriano, Christian, Sven, Hess-Stumpp, Holger, Augustin, Hellmut G., Müller-Decker, Karin, Nawroth, Peter P., Herzig, Stephan, Berriel Diaz, Mauricio
Published in Cell metabolism (05.12.2017)
Published in Cell metabolism (05.12.2017)
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Hypoxia-Inducible Lipid Droplet–Associated Is Not a Direct Physiological Regulator of Lipolysis in Adipose Tissue
Dijk, Wieneke, Mattijssen, Frits, de la Rosa Rodriguez, Montserrat, Loza Valdes, Angel, Loft, Anne, Mandrup, Susanne, Kalkhoven, Eric, Qi, Ling, Borst, Jan Willem, Kersten, Sander
Published in Endocrinology (Philadelphia) (01.05.2017)
Published in Endocrinology (Philadelphia) (01.05.2017)
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Angptl4 serves as an endogenous inhibitor of intestinal lipid digestion
Mattijssen, Frits, Alex, Sheril, Swarts, Hans J, Groen, Albert K, van Schothorst, Evert M, Kersten, Sander
Published in Molecular metabolism (Germany) (01.04.2014)
Published in Molecular metabolism (Germany) (01.04.2014)
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Dietary modulation of plasma angiopoietin-like protein 4 concentrations in healthy volunteers and in patients with type 2 diabetes
Jonker, Jacqueline T, Smit, Johannes WA, Hammer, Sebastiaan, Snel, Marieke, van der Meer, Rutger W, Lamb, Hildo J, Mattijssen, Frits, Mudde, Karin, Jazet, Ingrid M, Dekkers, Olaf M, de Roos, Albert, Romijn, Johannes A, Kersten, Sander, Rensen, Patrick CN
Published in The American journal of clinical nutrition (01.02.2013)
Published in The American journal of clinical nutrition (01.02.2013)
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Hepatic Deficiency in Transcriptional Cofactor TBL1 Promotes Liver Steatosis and Hypertriglyceridemia
Kulozik, Philipp, Jones, Allan, Mattijssen, Frits, Rose, Adam J., Reimann, Anja, Strzoda, Daniela, Kleinsorg, Stefan, Raupp, Christina, Kleinschmidt, Jürgen, Müller-Decker, Karin, Wahli, Walter, Sticht, Carsten, Gretz, Norbert, von Loeffelholz, Christian, Stockmann, Martin, Pfeiffer, Andreas, Stöhr, Sigrid, Dallinga-Thie, Geesje M., Nawroth, Peter P., Diaz, Mauricio Berriel, Herzig, Stephan
Published in Cell metabolism (06.04.2011)
Published in Cell metabolism (06.04.2011)
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Journal Article
Dietary modulation of plasma angiopoietin-like protein 4 concentrations in healthy volunteers and in patients with type 2 diabetes123
Jonker, Jacqueline T, Smit, Johannes WA, Hammer, Sebastiaan, Snel, Marieke, van der Meer, Rutger W, Lamb, Hildo J, Mattijssen, Frits, Mudde, Karin, Jazet, Ingrid M, Dekkers, Olaf M, de Roos, Albert, Romijn, Johannes A, Kersten, Sander, Rensen, Patrick CN
Published in The American journal of clinical nutrition (01.02.2013)
Published in The American journal of clinical nutrition (01.02.2013)
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Journal Article
Angptl4 protects against severe pro-inflammatory effects of dietary saturated fat by inhibiting lipoprotein lipase-dependent uptake of fatty acids in mesenteric lymph node macrophages
Lichtenstein, Laeticia, Mattijssen, Frits, de Wit, Nicole J., Georgiadi, Anastasia, Hooiveld, Guido J., van der Meer, Roelof, He, Yin, Qi, Ling, Köster, Anja, Tamsma, Jouke T., Tan, Nguan Soon, Müller, Michael, Kersten, Sander
Published in Cell metabolism (01.12.2010)
Published in Cell metabolism (01.12.2010)
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