Resveratrol derivatives as a pharmacological tool
Biasutto, Lucia, Mattarei, Andrea, Azzolini, Michele, Spina, Martina, Sassi, Nicola, Romio, Matteo, Paradisi, Cristina, Zoratti, Mario
Published in Annals of the New York Academy of Sciences (01.09.2017)
Published in Annals of the New York Academy of Sciences (01.09.2017)
Get full text
Journal Article
A Synthetic Fluorescent Mitochondria‐Targeted Sensor for Ratiometric Imaging of Calcium in Live Cells
Pendin, Diana, Norante, Rosa, De Nadai, Andrea, Gherardi, Gaia, Vajente, Nicola, Basso, Emy, Kaludercic, Nina, Mammucari, Cristina, Paradisi, Cristina, Pozzan, Tullio, Mattarei, Andrea
Published in Angewandte Chemie International Edition (15.07.2019)
Published in Angewandte Chemie International Edition (15.07.2019)
Get full text
Journal Article
Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction
Costa, Roberto, Peruzzo, Roberta, Bachmann, Magdalena, Montà, Giulia Dalla, Vicario, Mattia, Santinon, Giulia, Mattarei, Andrea, Moro, Enrico, Quintana-Cabrera, Rubén, Scorrano, Luca, Zeviani, Massimo, Vallese, Francesca, Zoratti, Mario, Paradisi, Cristina, Argenton, Francesco, Brini, Marisa, Calì, Tito, Dupont, Sirio, Szabò, Ildikò, Leanza, Luigi
Published in Cell reports (Cambridge) (20.08.2019)
Published in Cell reports (Cambridge) (20.08.2019)
Get full text
Journal Article
Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD
Li, Shuangxi, Wu, Zhihao, Li, Yu, Tantray, Ishaq, De Stefani, Diego, Mattarei, Andrea, Krishnan, Gopinath, Gao, Fen-Biao, Vogel, Hannes, Lu, Bingwei
Published in Cell reports (Cambridge) (04.08.2020)
Published in Cell reports (Cambridge) (04.08.2020)
Get full text
Journal Article
LETM1-Mediated K+ and Na+ Homeostasis Regulates Mitochondrial Ca2+ Efflux
Austin, Shane, Tavakoli, Mojtaba, Pfeiffer, Christina, Seifert, Julia, Mattarei, Andrea, De Stefani, Diego, Zoratti, Mario, Nowikovsky, Karin
Published in Frontiers in physiology (17.11.2017)
Published in Frontiers in physiology (17.11.2017)
Get full text
Journal Article
Esmethadone (REL-1017) and Other Uncompetitive NMDAR Channel Blockers May Improve Mood Disorders via Modulation of Synaptic Kinase-Mediated Signaling
Stahl, Stephen M., De Martin, Sara, Mattarei, Andrea, Bettini, Ezio, Pani, Luca, Guidetti, Clotilde, Folli, Franco, de Somer, Marc, Traversa, Sergio, Inturrisi, Charles E., Pappagallo, Marco, Gentilucci, Marco, Alimonti, Andrea, Fava, Maurizio, Manfredi, Paolo L.
Published in International journal of molecular sciences (13.10.2022)
Published in International journal of molecular sciences (13.10.2022)
Get full text
Journal Article
An agonist of the CXCR4 receptor accelerates the recovery from the peripheral neuroparalysis induced by Taipan snake envenomation
Stazi, Marco, D'Este, Giorgia, Mattarei, Andrea, Negro, Samuele, Lista, Florigio, Rigoni, Michela, Megighian, Aram, Montecucco, Cesare
Published in PLoS neglected tropical diseases (01.09.2020)
Published in PLoS neglected tropical diseases (01.09.2020)
Get full text
Journal Article
The mitochondrial ATP-dependent potassium channel (mitoKATP) controls skeletal muscle structure and function
Di Marco, Giulia, Gherardi, Gaia, De Mario, Agnese, Piazza, Ilaria, Baraldo, Martina, Mattarei, Andrea, Blaauw, Bert, Rizzuto, Rosario, De Stefani, Diego, Mammucari, Cristina
Published in Cell death & disease (17.01.2024)
Published in Cell death & disease (17.01.2024)
Get full text
Journal Article
Defective excitation-contraction coupling and mitochondrial respiration precede mitochondrial Ca2+ accumulation in spinobulbar muscular atrophy skeletal muscle
Marchioretti, Caterina, Zanetti, Giulia, Pirazzini, Marco, Gherardi, Gaia, Nogara, Leonardo, Andreotti, Roberta, Martini, Paolo, Marcucci, Lorenzo, Canato, Marta, Nath, Samir R., Zuccaro, Emanuela, Chivet, Mathilde, Mammucari, Cristina, Pacifici, Marco, Raffaello, Anna, Rizzuto, Rosario, Mattarei, Andrea, Desbats, Maria A., Salviati, Leonardo, Megighian, Aram, Sorarù, Gianni, Pegoraro, Elena, Belluzzi, Elisa, Pozzuoli, Assunta, Biz, Carlo, Ruggieri, Pietro, Romualdi, Chiara, Lieberman, Andrew P., Babu, Gopal J., Sandri, Marco, Blaauw, Bert, Basso, Manuela, Pennuto, Maria
Published in Nature communications (06.02.2023)
Published in Nature communications (06.02.2023)
Get full text
Journal Article
Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo
Bachmann, Magdalena, Rossa, Andrea, Varanita, Tatiana, Fioretti, Bernard, Biasutto, Lucia, Milenkovic, Stefan, Checchetto, Vanessa, Peruzzo, Roberta, Ahmad, Syed A., Patel, Sameer H., Lukowski, Robert, Edwards, Michael J., Ceccarelli, Matteo, Gulbins, Erich, Zoratti, Mario, Mattarei, Andrea, Szabo, Ildiko
Published in Cell death & disease (20.12.2022)
Published in Cell death & disease (20.12.2022)
Get full text
Journal Article
Mitochondria-targeted resveratrol derivatives act as cytotoxic pro-oxidants
Sassi, Nicola, Mattarei, Andrea, Azzolini, Michele, Bernardi, Paolo, Szabo', Ildiko', Paradisi, Cristina, Zoratti, Mario, Biasutto, Lucia
Published in Current pharmaceutical design (01.01.2014)
Published in Current pharmaceutical design (01.01.2014)
Get more information
Journal Article
DA7R: A 7-Letter Zip Code to Target PDAC
Parrasia, Sofia, Rossa, Andrea, Roncaglia, Nicola, Mattarei, Andrea, Honisch, Claudia, Szabò, Ildikò, Ruzza, Paolo, Biasutto, Lucia
Published in Pharmaceutics (16.05.2023)
Published in Pharmaceutics (16.05.2023)
Get full text
Journal Article
Pharmacological modulation of Kv1.3 potassium channel selectively triggers pathological B lymphocyte apoptosis in vivo in a genetic CLL model
Severin, Filippo, Urbani, Andrea, Varanita, Tatiana, Bachmann, Magdalena, Azzolini, Michele, Martini, Veronica, Pizzi, Marco, Tos, Angelo Paolo Dei, Frezzato, Federica, Mattarei, Andrea, Ghia, Paolo, Bertilaccio, Maria Teresa Sabrina, Gulbins, Erich, Paradisi, Cristina, Zoratti, Mario, Semenzato, Gianpietro Carlo, Leanza, Luigi, Trentin, Livio, Szabò, Ildiko
Published in Journal of experimental & clinical cancer research (16.02.2022)
Published in Journal of experimental & clinical cancer research (16.02.2022)
Get full text
Journal Article
Drug–Drug Interaction Studies of Esmethadone (REL-1017) Involving CYP3A4- and CYP2D6-Mediated Metabolism
Ferri, Nicola, De Martin, Sara, Stuart, James, Traversa, Sergio, Folli, Franco, Pappagallo, Marco, O’Gorman, Cedric, Guidetti, Clotilde, Mattarei, Andrea, Inturrisi, Charles E., Manfredi, Paolo L.
Published in Drugs in R&D (01.03.2024)
Published in Drugs in R&D (01.03.2024)
Get full text
Journal Article
Pharmacokinetics, Tolerability, and Safety of Esmethadone in Subjects with Chronic Kidney Disease or Hepatic Impairment
Ferri, Nicola, De Martin, Sara, Stuart, James, Traversa, Sergio, Mattarei, Andrea, Comai, Stefano, Folli, Franco, Pappagallo, Marco, Guidetti, Clotilde, Inturrisi, Charles E., Manfredi, Paolo L.
Published in Drugs in R&D (01.06.2024)
Published in Drugs in R&D (01.06.2024)
Get full text
Journal Article
The N-Methyl-D-Aspartate Receptor Blocker REL-1017 (Esmethadone) Reduces Calcium Influx Induced by Glutamate, Quinolinic Acid, and Gentamicin
Bettini, Ezio, De Martin, Sara, Mattarei, Andrea, Pappagallo, Marco, Stahl, Stephen M., Bifari, Francesco, Inturrisi, Charles E., Folli, Franco, Traversa, Sergio, Manfredi, Paolo L.
Published in Pharmaceuticals (Basel, Switzerland) (17.07.2022)
Published in Pharmaceuticals (Basel, Switzerland) (17.07.2022)
Get full text
Journal Article
Pharmacological Comparative Characterization of REL-1017 (Esmethadone-HCl) and Other NMDAR Channel Blockers in Human Heterodimeric N-Methyl-D-Aspartate Receptors
Bettini, Ezio, Stahl, Stephen M., De Martin, Sara, Mattarei, Andrea, Sgrignani, Jacopo, Carignani, Corrado, Nola, Selena, Locatelli, Patrizia, Pappagallo, Marco, Inturrisi, Charles E., Bifari, Francesco, Cavalli, Andrea, Alimonti, Andrea, Pani, Luca, Fava, Maurizio, Traversa, Sergio, Folli, Franco, Manfredi, Paolo L.
Published in Pharmaceuticals (Basel, Switzerland) (01.08.2022)
Published in Pharmaceuticals (Basel, Switzerland) (01.08.2022)
Get full text
Journal Article