Clinical impact of intratumoral HER2 heterogeneity on trastuzumab efficacy in patients with HER2-positive gastric cancer
Wakatsuki, Takeru, Yamamoto, Noriko, Sano, Takeshi, Chin, Keisho, Kawachi, Hiroshi, Takahari, Daisuke, Ogura, Mariko, Ichimura, Takashi, Nakayama, Izuma, Osumi, Hiroki, Matsushima, Tomohiro, Suenaga, Mitsukuni, Shinozaki, Eiji, Hiki, Naoki, Ishikawa, Yuichi, Yamaguchi, Kensei
Published in Journal of gastroenterology (01.11.2018)
Published in Journal of gastroenterology (01.11.2018)
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Journal Article
Distinct Binding Mode of Multikinase Inhibitor Lenvatinib Revealed by Biochemical Characterization
Okamoto, Kiyoshi, Ikemori-Kawada, Megumi, Jestel, Anja, von König, Konstanze, Funahashi, Yasuhiro, Matsushima, Tomohiro, Tsuruoka, Akihiko, Inoue, Atsushi, Matsui, Junji
Published in ACS medicinal chemistry letters (08.01.2015)
Published in ACS medicinal chemistry letters (08.01.2015)
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Journal Article
E7050: A dual c‐Met and VEGFR‐2 tyrosine kinase inhibitor promotes tumor regression and prolongs survival in mouse xenograft models
Nakagawa, Takayuki, Tohyama, Osamu, Yamaguchi, Atsumi, Matsushima, Tomohiro, Takahashi, Keiko, Funasaka, Setsuo, Shirotori, Shuji, Asada, Makoto, Obaishi, Hiroshi
Published in Cancer science (01.01.2010)
Published in Cancer science (01.01.2010)
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Journal Article
Efficacy of chemotherapy for patients with gastric cancer with early recurrence during or after adjuvant chemotherapy with S-1 alone: a multicenter retrospective study
Yamaguchi, Toshifumi, Kumagai, Koshi, Yagi, Shusuke, Nomura, Takashi, Nagashima, Kengo, Watanabe, Masaya, Makuuchi, Rie, Kawakami, Kentaro, Matsushima, Tomohiro, Kadowaki, Shigenori, Haruta, Shusuke, Cho, Haruhiko, Kakihara, Naoki, Otsuka, Shinya, Yamada, Takanobu, Imai, Yoshiro, Boku, Narikazu
Published in Scientific reports (19.09.2024)
Published in Scientific reports (19.09.2024)
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Journal Article
Multitargeting strategy using lenvatinib and golvatinib: Maximizing anti‐angiogenesis activity in a preclinical cancer model
Nakazawa, Youya, Kawano, Satoshi, Matsui, Junji, Funahashi, Yasuhiro, Tohyama, Osamu, Muto, Hiroki, Nakagawa, Takayuki, Matsushima, Tomohiro
Published in Cancer science (01.02.2015)
Published in Cancer science (01.02.2015)
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Journal Article
Nivolumab versus irinotecan as third- or later-line treatment for advanced gastric cancer: a multi-center retrospective study
Kumanishi, Ryosuke, Kadowaki, Shigenori, Mitani, Seiichiro, Matsushima, Tomohiro, Ogata, Takatsugu, Narita, Yukiya, Masuishi, Toshiki, Bando, Hideaki, Tajika, Masahiro, Yasui, Hisateru, Hara, Hiroki, Muro, Kei
Published in International journal of clinical oncology (01.06.2023)
Published in International journal of clinical oncology (01.06.2023)
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Journal Article
E7090, a Novel Selective Inhibitor of Fibroblast Growth Factor Receptors, Displays Potent Antitumor Activity and Prolongs Survival in Preclinical Models
Watanabe Miyano, Saori, Yamamoto, Yuji, Kodama, Kotaro, Miyajima, Yukiko, Mikamoto, Masaki, Nakagawa, Takayuki, Kuramochi, Hiroko, Funasaka, Setsuo, Nagao, Satoshi, Sugi, Naoko Hata, Okamoto, Kiyoshi, Minoshima, Yukinori, Nakatani, Yusuke, Karoji, Yuki, Ohashi, Isao, Yamane, Yoshinobu, Okada, Toshimi, Matsushima, Tomohiro, Matsui, Junji, Iwata, Masao, Uenaka, Toshimitsu, Tsuruoka, Akihiko
Published in Molecular cancer therapeutics (01.11.2016)
Published in Molecular cancer therapeutics (01.11.2016)
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Journal Article
Associations between early tumor shrinkage and depth of response and clinical outcomes in patients treated with 1st-line chemotherapy for advanced gastric cancer
Osumi, Hiroki, Takahari, Daisuke, Shinozaki, Eiji, Chin, Keisho, Ogura, Mariko, Wakatsuki, Takeru, Ichimura, Takashi, Nakayama, Izuma, Matsushima, Tomohiro, Yamaguchi, Kensei
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.03.2018)
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.03.2018)
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Journal Article
Lenvatinib in combination with golvatinib overcomes hepatocyte growth factor pathway‐induced resistance to vascular endothelial growth factor receptor inhibitor
Nakagawa, Takayuki, Matsushima, Tomohiro, Kawano, Satoshi, Nakazawa, Youya, Kato, Yu, Adachi, Yusuke, Abe, Takanori, Semba, Taro, Yokoi, Akira, Matsui, Junji, Tsuruoka, Akihiko, Funahashi, Yasuhiro
Published in Cancer science (01.06.2014)
Published in Cancer science (01.06.2014)
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Journal Article
A retrospective analysis of ramucirumab monotherapy in previously treated Japanese patients with advanced or metastatic gastric adenocarcinoma
Murahashi, Satoshi, Takahari, Daisuke, Wakatsuki, Takeru, Fukuda, Naoki, Ichimura, Takashi, Ogura, Mariko, Ozaka, Masato, Shinozaki, Eiji, Nakayama, Izuma, Matsushima, Tomohiro, Osumi, Hiroki, Chin, Keisho, Yamaguchi, Kensei
Published in International journal of clinical oncology (01.02.2018)
Published in International journal of clinical oncology (01.02.2018)
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Journal Article
Change in clinical outcomes during the transition of adjuvant chemotherapy for stage III colorectal cancer
Osumi, Hiroki, Shinozaki, Eiji, Suenaga, Mitsukuni, Wakatsuki, Takeru, Nakayama, Izuma, Matsushima, Tomohiro, Ogura, Mariko, Ichimura, Takashi, Takahari, Daisuke, Chin, Keisho, Nagasaki, Toshiya, Konishi, Tsuyoshi, Akiyoshi, Takashi, Fujimoto, Yoshiya, Nagayama, Satoshi, Fukunaga, Yosuke, Ueno, Masashi, Yamaguchi, Kensei
Published in PloS one (31.05.2017)
Published in PloS one (31.05.2017)
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Journal Article
Retrospective comparison of S-1 plus cisplatin versus S-1 monotherapy for the treatment of advanced gastric cancer patients with positive peritoneal cytology but without gross peritoneal metastasis
Nakayama, Izuma, Chin, Keisho, Matsushima, Tomohiro, Takahari, Daisuke, Ogura, Mariko, Shinozaki, Eiji, Suenaga, Mitsukuni, Ozaka, Masato, Wakatsuki, Takeru, Ichimura, Takashi, Hiroki, Osumi, Yamaguchi, Kensei
Published in International journal of clinical oncology (01.12.2017)
Published in International journal of clinical oncology (01.12.2017)
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Journal Article
Discovery of anti-inflammatory clinical candidate E6201, inspired from resorcylic lactone LL-Z1640-2, III
Shen, Yongchun, Boivin, Roch, Yoneda, Naoki, Du, Hong, Schiller, Shawn, Matsushima, Tomohiro, Goto, Masaki, Shirota, Hiroshi, Gusovsky, Fabian, Lemelin, Charles, Jiang, Yimin, Zhang, Zhiyi, Pelletier, Robert, Ikemori-Kawada, Megumi, Kawakami, Yoshiyuki, Inoue, Atsushi, Schnaderbeck, Matthew, Wang, Yuan
Published in Bioorganic & medicinal chemistry letters (15.05.2010)
Published in Bioorganic & medicinal chemistry letters (15.05.2010)
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Journal Article
Chemotherapeutic Strategies for Peritoneal Dissemination of Gastric Cancer
Matsushima, Tomohiro, Wakatsuki, Takeru, Takahari, Daisuke, Chin, Keisho, Yamaguchi, Kensei
Published in Gan to kagaku ryoho (01.12.2016)
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Published in Gan to kagaku ryoho (01.12.2016)
Journal Article
Discovery of an in vitro and in vivo potent resorcylic lactone analog of LL-Z1640-2 as anti-inflammatory lead, II
Shen, Yongchun, Du, Hong, Kotake, Makoto, Matsushima, Tomohiro, Goto, Masaki, Shirota, Hiroshi, Gusovsky, Fabian, Li, Xiangyi, Jiang, Yimin, Schiller, Shawn, Spyvee, Mark, Davis, Heather, Zhang, Zhiyi, Pelletier, Robert, Ikemori-Kawada, Megumi, Kawakami, Yoshiyuki, Inoue, Atsushi, Wang, Yuan
Published in Bioorganic & medicinal chemistry letters (15.05.2010)
Published in Bioorganic & medicinal chemistry letters (15.05.2010)
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Journal Article