Potent and orally bioavailable CCR4 antagonists: Synthesis and structure–activity relationship study of 2-aminoquinazolines
Yokoyama, Kazuhiro, Ishikawa, Noriko, Igarashi, Susumu, Kawano, Noriyuki, Masuda, Naoyuki, Hamaguchi, Wataru, Yamasaki, Shingo, Koganemaru, Yohei, Hattori, Kazuyuki, Miyazaki, Takahiro, Ogino, Shin-ichi, Matsumoto, Yuzo, Takeuchi, Makoto, Ohta, Mitsuaki
Published in Bioorganic & medicinal chemistry (2009)
Published in Bioorganic & medicinal chemistry (2009)
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Discovery of potent CCR4 antagonists: Synthesis and structure–activity relationship study of 2,4-diaminoquinazolines
Yokoyama, Kazuhiro, Ishikawa, Noriko, Igarashi, Susumu, Kawano, Noriyuki, Hattori, Kazuyuki, Miyazaki, Takahiro, Ogino, Shin-ichi, Matsumoto, Yuzo, Takeuchi, Makoto, Ohta, Mitsuaki
Published in Bioorganic & medicinal chemistry (15.07.2008)
Published in Bioorganic & medicinal chemistry (15.07.2008)
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Biochemical and pharmacological characterization of YM-60828, a newly synthesized and orally active inhibitor of human factor Xa
Taniuchi, Y, Sakai, Y, Hisamichi, N, Kayama, M, Mano, Y, Sato, K, Hirayama, F, Koshio, H, Matsumoto, Y, Kawasaki, T
Published in Thrombosis and haemostasis (01.03.1998)
Published in Thrombosis and haemostasis (01.03.1998)
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Synthesis and biological activity of novel 1,2-disubstituted benzene derivatives as factor Xa inhibitors
Koshio, Hiroyuki, Hirayama, Fukushi, Ishihara, Tsukasa, Shiraki, Ryouta, Shigenaga, Takeshi, Taniuchi, Yuta, Sato, Kazuo, Moritani, Yumiko, Iwatsuki, Yoshiyuki, Kaku, Seiji, Katayama, Naoko, Kawasaki, Tomihisa, Matsumoto, Yuzo, Sakamoto, Shuichi, Tsukamoto, Shin-ichi
Published in Bioorganic & medicinal chemistry (15.02.2005)
Published in Bioorganic & medicinal chemistry (15.02.2005)
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The discovery of YM-60828: A potent, selective and orally-bioavailable factor Xa inhibitor
HIRAYAMA, Fukushi, KOSHIO, Hiroyuki, YANAGISAWA, Isao, KATAYAMA, Naoko, KURIHARA, Hiroyuki, TANIUCHI, Yuta, SATO, Kazuo, HISAMICHI, Nami, SAKAI-MORITANI, Yumiko, KAWASAKI, Tomihisa, MATSUMOTO, Yuzo
Published in Bioorganic & medicinal chemistry (01.05.2002)
Published in Bioorganic & medicinal chemistry (01.05.2002)
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Outcome of Moyamoya disease in our institute: comparing analyses of initial and recurrent patients
Ono, Yasuhiro, Morimoto, Jun, Hisamatsu, Yoshio, Kuramoto, Satoshi, Katsumata, Atsushi, Kawauchi, Masamitsu, Matsumoto, Yuzo
Published in Japanese Journal of Stroke (25.11.2013)
Published in Japanese Journal of Stroke (25.11.2013)
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YM-60828, a novel factor Xa inhibitor: Separation of its antithrombotic effects from its prolongation of bleeding time
Sato, Kazuo, Kawasaki, Tomihisa, Taniuchi, Yuta, Hirayama, Fukushi, Koshio, Hiroyuki, Matsumoto, Yuzo
Published in European journal of pharmacology (27.11.1997)
Published in European journal of pharmacology (27.11.1997)
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An Easy Access to 7-Methyl-2-naphthalenecarbonitrile
Koshio, Hiroyuki, Ishihara, Tsukasa, Yamada, Hiroyoshi, Hirayama, Fukushi, Matsumoto, Yuzo, Yanagisawa, Isao
Published in Chemical & Pharmaceutical Bulletin (01.04.2005)
Published in Chemical & Pharmaceutical Bulletin (01.04.2005)
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Antithrombotic effects of YM‐60828, a newly synthesized factor Xa inhibitor, in rat thrombosis models and its effects on bleeding time
Sato, Kazuo, Kawasaki, Tomihisa, Hisamichi, Nami, Taniuchi, Yuta, Hirayama, Fukushi, Koshio, Hiroyuki, Matsumoto, Yuzo
Published in British journal of pharmacology (01.01.1998)
Published in British journal of pharmacology (01.01.1998)
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Orally active factor Xa inhibitor: synthesis and biological activity of masked amidines as prodrugs of novel 1,4-diazepane derivatives
Koshio, Hiroyuki, Hirayama, Fukushi, Ishihara, Tsukasa, Kaizawa, Hiroyuki, Shigenaga, Takeshi, Taniuchi, Yuta, Sato, Kazuo, Moritani, Yumiko, Iwatsuki, Yoshiyuki, Uemura, Toshio, Kaku, Seiji, Kawasaki, Tomihisa, Matsumoto, Yuzo, Sakamoto, Shuichi, Tsukamoto, Shin-ichi
Published in Bioorganic & medicinal chemistry (15.10.2004)
Published in Bioorganic & medicinal chemistry (15.10.2004)
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Antitumor effects of gefitinib for metastatic brain tumors from lung carcinomas with EGFR mutation
Ono, Yasuhiro, Toyota, Yasunori, Toyoshima, Atsuhiko, Kuramoto, Satoshi, Katzumata, Atsushi, Kawauchi, Masamitsu, Matsumoto, Yuzo
Published in Nō shinkei geka (01.06.2011)
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Published in Nō shinkei geka (01.06.2011)
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Design, synthesis and biological activity of YM-60828 derivatives. Part 2: potent and orally-bioavailable factor Xa inhibitors based on benzothiadiazine-4-one template
Hirayama, Fukushi, Koshio, Hiroyuki, Katayama, Naoko, Ishihara, Tsukasa, Kaizawa, Hiroyuki, Taniuchi, Yuta, Sato, Kazuo, Sakai-Moritani, Yumiko, Kaku, Seiji, Kurihara, Hiroyuki, Kawasaki, Tomihisa, Matsumoto, Yuzo, Sakamoto, Shuichi, Tsukamoto, Shin-ichi
Published in Bioorganic & medicinal chemistry (06.02.2003)
Published in Bioorganic & medicinal chemistry (06.02.2003)
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Design, synthesis and biological activity of YM-60828 derivatives: Potent and orally-bioavailable factor Xa inhibitors based on naphthoanilide and naphthalensulfonanilide templates
HIRAYAMA, Fukushi, KOSHIO, Hiroyuki, SATO, Kazuo, SAKAI-MORITANI, Yumiko, KAKU, Seiji, KAWASAKI, Tomihisa, MATSUMOTO, Yuzo, SAKAMOTO, Shuichi, TSUKAMOTO, Shin-Ichi, ISHIHARA, Tsukasa, WATANUKI, Susumu, HACHIYA, Shunichiro, KAIZAWA, Hiroyuki, KURAMOCHI, Takahiro, KATAYAMA, Naoko, KURIHARA, Hiroyuki, TANIUCHI, Yuta
Published in Bioorganic & medicinal chemistry (01.08.2002)
Published in Bioorganic & medicinal chemistry (01.08.2002)
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Comparative studies of an orally-active factor Xa inhibitor, YM-60828, with other antithrombotic agents in a rat model of arterial thrombosis
Kawasaki, T, Sato, K, Sakai, Y, Hirayama, F, Koshio, H, Taniuchi, Y, Matsumoto, Y
Published in Thrombosis and haemostasis (01.02.1998)
Published in Thrombosis and haemostasis (01.02.1998)
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A case of progressive multifocal leukoencephalopathy with alcoholic liver dysfunction
Ono, Yasuhiro, Kikuchi, Yoichiro, Katsumata, Atsushi, Nishio, Shinsaku, Kawauchi, Masamitsu, Matsumoto, Yuzo, Nakamura, Satoko, Mano, Shohey
Published in Nō shinkei geka (01.06.2010)
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Published in Nō shinkei geka (01.06.2010)
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Outcome after External Decompression for Massive Cerebral Infarction
SAKAI, Kyoji, IWAHASHI, Kazuko, TERADA, Kinya, GOHDA, Yuji, SAKURAI, Masaru, MATSUMOTO, Yuzo
Published in Neurologia medico-chirurgica (1998)
Published in Neurologia medico-chirurgica (1998)
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Relationship between the antithrombotic effect of YM-75466, a novel factor Xa inhibitor, and coagulation parameters in rats
Sato, Kazuo, Taniuchi, Yuta, Kawasaki, Tomihisa, Hirayama, Fukushi, Koshio, Hiroyuki, Matsumoto, Yuzo
Published in European journal of pharmacology (24.04.1998)
Published in European journal of pharmacology (24.04.1998)
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