In Vitro Activity of E1210, a Novel Antifungal, against Clinically Important Yeasts and Molds
MIYAZAKI, Mamiko, HORII, Takaaki, ABE, Shinya, YOSHIMATSU, Kentaro, ASADA, Makoto, HATA, Katsura, WATANABE, Nao-Aki, NAKAMOTO, Kazutaka, TANAKA, Keigo, SHIROTORI, Syuji, MURAI, Norio, INOUE, Satoshi, MATSUKURA, Masayuki
Published in Antimicrobial Agents and Chemotherapy (01.10.2011)
Published in Antimicrobial Agents and Chemotherapy (01.10.2011)
Get full text
Journal Article
Efficacy of Oral E1210, a New Broad-Spectrum Antifungal with a Novel Mechanism of Action, in Murine Models of Candidiasis, Aspergillosis, and Fusariosis
Hata, Katsura, Horii, Takaaki, Miyazaki, Mamiko, Watanabe, Nao-aki, Okubo, Miyuki, Sonoda, Jiro, Nakamoto, Kazutaka, Tanaka, Keigo, Shirotori, Syuji, Murai, Norio, Inoue, Satoshi, Matsukura, Masayuki, Abe, Shinya, Yoshimatsu, Kentaro, Asada, Makoto
Published in Antimicrobial Agents and Chemotherapy (01.10.2011)
Published in Antimicrobial Agents and Chemotherapy (01.10.2011)
Get full text
Journal Article
Synthesis and evaluation of novel antifungal agents-quinoline and pyridine amide derivatives
Nakamoto, Kazutaka, Tsukada, Itaru, Tanaka, Keigo, Matsukura, Masayuki, Haneda, Toru, Inoue, Satoshi, Murai, Norio, Abe, Shinya, Ueda, Norihiro, Miyazaki, Mamiko, Watanabe, Naoaki, Asada, Makoto, Yoshimatsu, Kentaro, Hata, Katsura
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Get full text
Journal Article
An Effective Synthesis of a (Pyridin-3-yl)isoxazole via 1,3-Dipolar Cycloaddition Using ZnCl2: Synthesis of a (2-Aminopyridin-3-yl)isoxazole Derivative and Its Antifungal Activity
Tanaka, Keigo, Inoue, Satoshi, Murai, Norio, Shiroton, Syuji, Nakamoto, Kazutaka, Abe, Shinya, Horii, Takaaki, Miyazaki, Mamiko, Hata, Katsura, Watanabe, Naoaki, Asada, Makoto, Matsukura, Masayuki
Published in Chemistry letters (2010)
Published in Chemistry letters (2010)
Get more information
Journal Article
E7386, a Selective Inhibitor of the Interaction between β-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling
Yamada, Kazuhiko, Hori, Yusaku, Inoue, Satoshi, Yamamoto, Yuji, Iso, Kentaro, Kamiyama, Hiroshi, Yamaguchi, Atsumi, Kimura, Takayuki, Uesugi, Mai, Ito, Junichi, Matsuki, Masahiro, Nakamoto, Kazutaka, Harada, Hitoshi, Yoneda, Naoki, Takemura, Atsushi, Kushida, Ikuo, Wakayama, Naomi, Kubara, Kenji, Kato, Yu, Semba, Taro, Yokoi, Akira, Matsukura, Masayuki, Odagami, Takenao, Iwata, Masao, Tsuruoka, Akihiko, Uenaka, Toshimitsu, Matsui, Junji, Matsushima, Tomohiro, Nomoto, Kenichi, Kouji, Hiroyuki, Owa, Takashi, Funahashi, Yasuhiro, Ozawa, Yoichi
Published in Cancer research (Chicago, Ill.) (15.02.2021)
Published in Cancer research (Chicago, Ill.) (15.02.2021)
Get full text
Journal Article
Lenvatinib, an angiogenesis inhibitor targeting VEGFR/FGFR, shows broad antitumor activity in human tumor xenograft models associated with microvessel density and pericyte coverage
Yamamoto, Yuji, Matsui, Junji, Matsushima, Tomohiro, Obaishi, Hiroshi, Miyazaki, Kazuki, Nakamura, Katsuji, Tohyama, Osamu, Semba, Taro, Yamaguchi, Atsumi, Hoshi, Sachi Suzuki, Mimura, Fusayo, Haneda, Toru, Fukuda, Yoshio, Kamata, Jun-Ichi, Takahashi, Keiko, Matsukura, Masayuki, Wakabayashi, Toshiaki, Asada, Makoto, Nomoto, Ken-Ichi, Watanabe, Tatsuo, Dezso, Zoltan, Yoshimatsu, Kentaro, Funahashi, Yasuhiro, Tsuruoka, Akihiko
Published in Vascular cell (06.09.2014)
Published in Vascular cell (06.09.2014)
Get full text
Journal Article
Ten-Gram-Scale Total Synthesis of the Anticancer Drug Candidate E7130 to Supply Clinical Trials
Kaburagi, Yosuke, Kira, Kazunobu, Yahata, Kenzo, Iso, Kentaro, Sato, Yuki, Matsuura, Fumiyoshi, Ohashi, Isao, Matsumoto, Yasunobu, Isomura, Minetaka, Sasaki, Takeo, Fukuyama, Takashi, Miyashita, Yusuke, Azuma, Hiroshi, Iida, Daisuke, Ishida, Tasuku, Itano, Wataru, Matsuda, Masaaki, Matsukura, Masayuki, Murai, Norio, Nagao, Satoshi, Seki, Masashi, Yamamoto, Akihiko, Yamamoto, Yuji, Yoneda, Naoki, Watanabe, Yuzo, Kamada, Atsushi, Kayano, Akio, Tagami, Katsuya, Asano, Osamu, Owa, Takashi, Kishi, Yoshito
Published in Organic letters (12.04.2024)
Published in Organic letters (12.04.2024)
Get full text
Journal Article
What Does It Take to Develop Structurally Complex Molecules by Total Synthesis? Rapid Process Development and GMP Manufacturing of E7130 Drug Substance for First-in-Human Clinical Study
Sasaki, Takeo, Yahata, Kenzo, Isomura, Minetaka, Ohashi, Isao, Fukuyama, Takashi, Miyashita, Yusuke, Watanabe, Yuzo, Murai, Norio, Matsuda, Masaaki, Kamada, Atsushi, Kaburagi, Yosuke, Kira, Kazunobu, Iso, Kentaro, Sato, Yuki, Matsuura, Fumiyoshi, Matsumoto, Yasunobu, Azuma, Hiroshi, Iida, Daisuke, Ishida, Tasuku, Itano, Wataru, Nagao, Satoshi, Seki, Masashi, Yamamoto, Akihiko, Yamamoto, Yuji, Yoneda, Naoki, Matsukura, Masayuki, Asano, Osamu, Kayano, Akio, Tagami, Katsuya, Owa, Takashi, Kishi, Yoshito
Published in Organic process research & development (21.06.2024)
Published in Organic process research & development (21.06.2024)
Get full text
Journal Article
Abstract 5177: E7386 : First-in-class orally active CBP/beta-catenin modulator as an anticancer agent
Yamada, Kazuhiko, Hori, Yusaku, Yamaguchi, Atsumi, Matsuki, Masahiro, Tsukamoto, Shuntaro, Yokoi, Akira, Semba, Taro, Ozawa, Yoichi, Inoue, Satoshi, Yamamoto, Yuji, Iso, Kentaro, Nakamoto, Kazutaka, Harada, Hitoshi, Yoneda, Naoki, Takemura, Atsushi, Matsukura, Masayuki, Kubara, Kenji, Odagami, Takenao, Iwata, Masao, Tsuruoka, Akihiko, Uenaka, Toshimitsu, Matsui, Junji, Matsushima, Tomohiro, Nomoto, Kenich, Kouji, Hiroyuki, Owa, Takashi
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Get full text
Journal Article
Synthesis and Antiarrhythmic Activity of 2, 2-Dialkyl-1'-(N-substituted aminoalkyl)-spiro-[chroman-4, 4'-imidazolidine]-2', 5'-diones
MATSUKURA, Masayuki, DAIKU, Yoshiharu, UEDA, Kouichirou, TANAKA, Satoru, IGARASHI, Toshiji, MINAMI, Norio
Published in Chemical & pharmaceutical bulletin (01.07.1992)
Published in Chemical & pharmaceutical bulletin (01.07.1992)
Get full text
Journal Article
4-Benzylamino-1-chloro-6-substituted Phthalazines: Synthesis and Inhibitory Activity toward Phosphodiesterase 5
Watanabe, Nobuhisa, Kabasawa, Yasuhiro, Takase, Yasutaka, Matsukura, Masayuki, Miyazaki, Kazuki, Ishihara, Hiroki, Kodama, Kohtarou, Adachi, Hideyuki
Published in Journal of medicinal chemistry (27.08.1998)
Published in Journal of medicinal chemistry (27.08.1998)
Get full text
Journal Article
2-Alkynyl-8-aryl-9-methyladenines as Novel Adenosine Receptor Antagonists: Their Synthesis and Structure−Activity Relationships toward Hepatic Glucose Production Induced via Agonism of the A2B Receptor
Harada, Hitoshi, Asano, Osamu, Hoshino, Yorihisa, Yoshikawa, Seiji, Matsukura, Masayuki, Kabasawa, Yasuhiro, Niijima, Jun, Kotake, Yoshihiko, Watanabe, Nobuhisa, Kawata, Tsutomu, Inoue, Takashi, Horizoe, Tatsuo, Yasuda, Nobuyuki, Minami, Hiroe, Nagata, Kaya, Murakami, Manabu, Nagaoka, Junsaku, Kobayashi, Seiichi, Tanaka, Isao, Abe, Shinya
Published in Journal of medicinal chemistry (18.01.2001)
Published in Journal of medicinal chemistry (18.01.2001)
Get full text
Journal Article
Synthesis and Cardiovascular Activity of Phenylalkylamine Derivatives. I. Potential Specific Bradycardic Agents
OZAKI, Fumihiro, MATSUKURA, Masayuki, KABASAWA, Yasuhiro, ISHIBASHI, Keiji, IKEMORI, Megumi, HAMANO, Sachiyuki, MINAMI, Norio
Published in Chemical & pharmaceutical bulletin (1992)
Published in Chemical & pharmaceutical bulletin (1992)
Get full text
Journal Article