Synthesis of a Cytotoxic Amanitin for Biorthogonal Conjugation
Zhao, Liang, May, Jonathan P., Blanc, Antoine, Dietrich, David J., Loonchanta, Anastak, Matinkhoo, Kaveh, Pryyma, Alla, Perrin, David M.
Published in Chembiochem : a European journal of chemical biology (06.07.2015)
Published in Chembiochem : a European journal of chemical biology (06.07.2015)
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Journal Article
Synthesis of the Death-Cap Mushroom Toxin α‑Amanitin
Matinkhoo, Kaveh, Pryyma, Alla, Todorovic, Mihajlo, Patrick, Brian O, Perrin, David M
Published in Journal of the American Chemical Society (30.05.2018)
Published in Journal of the American Chemical Society (30.05.2018)
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Journal Article
Scaling Amatoxin Synthesis with an Improved Route to (2S,3R,4R)‑Dihydroxyisoleucine Exemplified by a Toxic, Clickable α‑Amanitin Analogue
Hambira, Chido M, Matinkhoo, Kaveh, Pryyma, Alla, Patrick, Brian O, Perrin, David M
Published in Journal of organic chemistry (02.04.2021)
Published in Journal of organic chemistry (02.04.2021)
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Journal Article
Synthesis and evaluation of "Ama-Flash", a photocaged amatoxin prodrug for light-activated RNA Pol II inhibition and cell death
Matinkhoo, Kaveh, Pryyma, Alla, Wong, Antonio A. W. L., Perrin, David M.
Published in Chemical communications (Cambridge, England) (25.09.2021)
Published in Chemical communications (Cambridge, England) (25.09.2021)
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Journal Article
Novel Psilocin Prodrugs with Altered Pharmacological Properties as Candidate Therapies for Treatment-Resistant Anxiety Disorders
Raithatha, Sheetal A., Hagel, Jillian M., Matinkhoo, Kaveh, Yu, Lisa, Press, David, Cook, Sarah G., Sharma, Govinda, Dhananjaya, D., Jensen, Glynnis, Lee, Jessica B., Cai, Charlie, Gallant, Jonathan, Bains, Jaideep, Tucker, Joseph E., Facchini, Peter J.
Published in Journal of medicinal chemistry (25.01.2024)
Published in Journal of medicinal chemistry (25.01.2024)
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Journal Article
Cover Feature: Design, Synthesis, and Biochemical Evaluation of Alpha‐Amanitin Derivatives Containing Analogs of the trans‐Hydroxyproline Residue for Potential Use in Antibody‐Drug Conjugates (Chem. Eur. J. 40/2021)
Matinkhoo, Kaveh, Wong, Antonio A. W. L., Hambira, Chido M., Kato, Brandon, Wei, Charlie, Müller, Christoph, Hechler, Torsten, Braun, Alexandra, Gallo, Francesca, Pahl, Andreas, Perrin, David M.
Published in Chemistry : a European journal (16.07.2021)
Published in Chemistry : a European journal (16.07.2021)
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Journal Article
Design, Synthesis, and Biochemical Evaluation of Alpha‐Amanitin Derivatives Containing Analogs of the trans‐Hydroxyproline Residue for Potential Use in Antibody‐Drug Conjugates
Matinkhoo, Kaveh, Wong, Antonio A. W. L., Hambira, Chido M., Kato, Brandon, Wei, Charlie, Müller, Christoph, Hechler, Torsten, Braun, Alexandra, Gallo, Francesca, Pahl, Andreas, Perrin, David M.
Published in Chemistry : a European journal (16.07.2021)
Published in Chemistry : a European journal (16.07.2021)
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Journal Article
Synthesis and preliminary evaluation of octreotate conjugates of bioactive synthetic amatoxins for targeting somatostatin receptor (sstr2) expressing cells
Pryyma, Alla, Matinkhoo, Kaveh, Bu, Yong Jia, Merkens, Helen, Zhang, Zhengxing, Bénard, Francois, Perrin, David M
Published in RSC chemical biology (05.01.2022)
Published in RSC chemical biology (05.01.2022)
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Journal Article
C4-carboxylic acid-substituted tryptamine derivatives and methods of using
Hagel, Jillian M, Matinkhoo, Kaveh, Press, David James, Jensen, Glynnis Elizabeth, Cai, Ye, Facchini, Peter J
Year of Publication 03.09.2024
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Year of Publication 03.09.2024
Patent
C4-carboxylic acid-substituted tryptamine derivatives and methods of using
Hagel, Jillian M, Matinkhoo, Kaveh, Press, David James, Jensen, Glynnis Elizabeth, Cai, Ye, Facchini, Peter J
Year of Publication 20.08.2024
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Year of Publication 20.08.2024
Patent
SUBSTITUTED ETHYLAMINE FUSED HETEROCYCLIC MESCALINE DERIVATIVES
Cai, Charlie, Hagel, Jillian M, Matinkhoo, Kaveh, Press, David James, Facchini, Peter J, Lee, Jessica
Year of Publication 25.07.2024
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Year of Publication 25.07.2024
Patent