Altered cellular metabolism in gliomas — an emerging landscape of actionable co-dependency targets
Bi, Junfeng, Chowdhry, Sudhir, Wu, Sihan, Zhang, Wenjing, Masui, Kenta, Mischel, Paul S.
Published in Nature reviews. Cancer (01.01.2020)
Published in Nature reviews. Cancer (01.01.2020)
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Journal Article
The metabolomic landscape plays a critical role in glioma oncogenesis
Masui, Kenta, Cavenee, Webster K., Mischel, Paul S., Shibata, Noriyuki
Published in Cancer science (01.05.2022)
Published in Cancer science (01.05.2022)
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Journal Article
mTORC2 in the center of cancer metabolic reprogramming
Masui, Kenta, Cavenee, Webster K, Mischel, Paul S
Published in Trends in endocrinology and metabolism (01.07.2014)
Published in Trends in endocrinology and metabolism (01.07.2014)
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Journal Article
mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT
Gu, Yuchao, Albuquerque, Claudio P., Braas, Daniel, Zhang, Wei, Villa, Genaro R., Bi, Junfeng, Ikegami, Shiro, Masui, Kenta, Gini, Beatrice, Yang, Huijun, Gahman, Timothy C., Shiau, Andrew K., Cloughesy, Timothy F., Christofk, Heather R., Zhou, Huilin, Guan, Kun-Liang, Mischel, Paul S.
Published in Molecular cell (06.07.2017)
Published in Molecular cell (06.07.2017)
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Journal Article
Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment
Tanaka, Kazuhiro, Sasayama, Takashi, Irino, Yasuhiro, Takata, Kumi, Nagashima, Hiroaki, Satoh, Naoko, Kyotani, Katsusuke, Mizowaki, Takashi, Imahori, Taichiro, Ejima, Yasuo, Masui, Kenta, Gini, Beatrice, Yang, Huijun, Hosoda, Kohkichi, Sasaki, Ryohei, Mischel, Paul S, Kohmura, Eiji
Published in The Journal of clinical investigation (01.04.2015)
Published in The Journal of clinical investigation (01.04.2015)
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Journal Article
Metabolic state of glioma stem cells and nontumorigenic cells
Vlashi, Erina, Lagadec, Chann, Vergnes, Laurent, Matsutani, Tomoo, Masui, Kenta, Poulou, Maria, Popescu, Ruxandra, Della Donna, Lorenza, Evers, Patrick, Dekmezian, Carmen, Reue, Karen, Christofk, Heather, Mischel, Paul S, Pajonk, Frank
Published in Proceedings of the National Academy of Sciences - PNAS (20.09.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (20.09.2011)
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Journal Article
Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA
Nathanson, David A., Gini, Beatrice, Mottahedeh, Jack, Visnyei, Koppany, Koga, Tomoyuki, Gomez, German, Estin, Ascia, Hwang, Kiwook, Wang, Jun, Masui, Kenta, Paucar, Andres, Yang, Huijun, Ohashi, Minori, Zhu, Shaojun, Wykosky, Jill, Reed, Rachel, Nelson, Stanley F., Cloughesy, Timothy F., James, C. David, Rao, P. Nagesh, Kornblum, Harley I., Heath, James R., Cavenee, Webster K., Furnari, Frank B., Mischel, Paul S.
Published in Science (American Association for the Advancement of Science) (03.01.2014)
Published in Science (American Association for the Advancement of Science) (03.01.2014)
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Journal Article
Clinical features and difficulty in diagnosis of Langerhans cell histiocytosis in the hypothalamic-pituitary region
Oda, Yuichi, Amano, Kosaku, Seki, Yasufumi, Kimura, Shihori, Yamashita, Kaoru, Masui, Kenta, Komori, Takashi, Ichihara, Atsuhiro, Kawamata, Takakazu
Published in ENDOCRINE JOURNAL (01.01.2022)
Published in ENDOCRINE JOURNAL (01.01.2022)
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Journal Article
mTOR complex 2 is an integrator of cancer metabolism and epigenetics
Masui, Kenta, Harachi, Mio, Cavenee, Webster K., Mischel, Paul S., Shibata, Noriyuki
Published in Cancer letters (28.05.2020)
Published in Cancer letters (28.05.2020)
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Journal Article
mTOR Complex 2 Controls Glycolytic Metabolism in Glioblastoma through FoxO Acetylation and Upregulation of c-Myc
Masui, Kenta, Tanaka, Kazuhiro, Akhavan, David, Babic, Ivan, Gini, Beatrice, Matsutani, Tomoo, Iwanami, Akio, Liu, Feng, Villa, Genaro R., Gu, Yuchao, Campos, Carl, Zhu, Shaojun, Yang, Huijun, Yong, William H., Cloughesy, Timothy F., Mellinghoff, Ingo K., Cavenee, Webster K., Shaw, Reuben J., Mischel, Paul S.
Published in Cell metabolism (05.11.2013)
Published in Cell metabolism (05.11.2013)
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Journal Article
Metabolic reprogramming in the pathogenesis of glioma: Update
Masui, Kenta, Onizuka, Hiromi, Cavenee, Webster K., Mischel, Paul S., Shibata, Noriyuki
Published in Neuropathology (01.02.2019)
Published in Neuropathology (01.02.2019)
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Journal Article
Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma
Wei, Wei, Shin, Young Shik, Xue, Min, Matsutani, Tomoo, Masui, Kenta, Yang, Huijun, Ikegami, Shiro, Gu, Yuchao, Herrmann, Ken, Johnson, Dazy, Ding, Xiangming, Hwang, Kiwook, Kim, Jungwoo, Zhou, Jian, Su, Yapeng, Li, Xinmin, Bonetti, Bruno, Chopra, Rajesh, James, C. David, Cavenee, Webster K., Cloughesy, Timothy F., Mischel, Paul S., Heath, James R., Gini, Beatrice
Published in Cancer cell (11.04.2016)
Published in Cancer cell (11.04.2016)
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Journal Article
Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance
Masui, Kenta, Kazuhiro Tanaka, Shiro Ikegami, Genaro R. Villa, Huijun Yang, William H. Yong, Timothy F. Cloughesy, Kanato Yamagata, Nobutaka Arai, Webster K. Cavenee, Paul S. Mischel
Published in Proceedings of the National Academy of Sciences - PNAS (28.07.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (28.07.2015)
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Journal Article
Dual Regulation of Histone Methylation by mTOR Complexes Controls Glioblastoma Tumor Cell Growth via EZH2 and SAM
Harachi, Mio, Masui, Kenta, Honda, Hiroaki, Muragaki, Yoshihiro, Kawamata, Takakazu, Cavenee, Webster K, Mischel, Paul S, Shibata, Noriyuki
Published in Molecular cancer research (01.08.2020)
Published in Molecular cancer research (01.08.2020)
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Journal Article
Astrocytes release glutamate via cystine/glutamate antiporter upregulated in response to increased oxidative stress related to sporadic amyotrophic lateral sclerosis
Kazama, Miku, Kato, Yoichiro, Kakita, Akiyoshi, Noguchi, Noriko, Urano, Yasuomi, Masui, Kenta, Niida‐Kawaguchi, Motoko, Yamamoto, Tomoko, Watabe, Kazuhiko, Kitagawa, Kazuo, Shibata, Noriyuki
Published in Neuropathology (01.12.2020)
Published in Neuropathology (01.12.2020)
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Journal Article
mTOR Complexes as a Nutrient Sensor for Driving Cancer Progression
Harachi, Mio, Masui, Kenta, Okamura, Yukinori, Tsukui, Ryota, Mischel, Paul S, Shibata, Noriyuki
Published in International journal of molecular sciences (21.10.2018)
Published in International journal of molecular sciences (21.10.2018)
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