Collective synthesis of natural products by means of organocascade catalysis
Jones, Spencer B., Simmons, Bryon, Mastracchio, Anthony, MacMillan, David W. C.
Published in Nature (London) (14.07.2011)
Published in Nature (London) (14.07.2011)
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Journal Article
Direct and enantioselective α-allylation of ketones via singly occupied molecular orbital (SOMO) catalysis
Mastracchio, Anthony, Warkentin, Alexander A, Walji, Abbas M, MacMillan, David W.C
Published in Proceedings of the National Academy of Sciences - PNAS (30.11.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (30.11.2010)
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Journal Article
Discovery of a Potent and Selective Covalent p300/CBP Inhibitor
Mastracchio, Anthony, Lai, Chunqiu, Digiammarino, Enrico, Ready, Damien B, Lasko, Loren M, Bromberg, Kenneth D, McClellan, William J, Montgomery, Debra, Manaves, Vlasios, Shaw, Bailin, Algire, Mikkel, Patterson, Melanie J, Sun, Chaohong C, Rosenberg, Saul, Lai, Albert, Michaelides, Michael R
Published in ACS medicinal chemistry letters (13.05.2021)
Published in ACS medicinal chemistry letters (13.05.2021)
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Journal Article
Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients
Yuda, Junichiro, Will, Christine, Phillips, Darren C., Abraham, Linu, Alvey, Cory, Avigdor, Abraham, Buck, Wayne, Besenhofer, Lauren, Boghaert, Erwin, Cheng, Dong, Cojocari, Dan, Doyle, Kelly, Hansen, T. Matthew, Huang, Kevin, Johnson, Eric F., Judd, Andrew S., Judge, Russell A., Kalvass, John C., Kunzer, Aaron, Lam, Lloyd T., Li, Rachel, Martin, Ruth L., Mastracchio, Anthony, Mitten, Mike, Petrich, Adam, Wang, Jin, Ward, James E., Zhang, Haichao, Wang, Xilu, Wolff, Johannes E., Bell-McGuinn, Katherine M., Souers, Andrew J.
Published in Communications medicine (25.10.2023)
Published in Communications medicine (25.10.2023)
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Crystal Structure of Human Phosphodiesterase 3B: Atomic Basis for Substrate and Inhibitor Specificity
Scapin, Giovanna, Patel, Sangita B, Chung, Christine, Varnerin, Jeffrey P, Edmondson, Scott D, Mastracchio, Anthony, Parmee, Emma R, Singh, Suresh B, Becker, Joseph W, Van der Ploeg, Lex H. T, Tota, Michael R
Published in Biochemistry (Easton) (25.05.2004)
Published in Biochemistry (Easton) (25.05.2004)
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Journal Article
Interspecies in vitro metabolism of the phosphodiesterase-4 (PDE4) inhibitor L-454,560
Bateman, Kevin P., Trimble, Laird, Chauret, Nathalie, Silva, Jose, Day, Stephen, Macdonald, Dwight, Dube, Daniel, Gallant, Michel, Mastracchio, Anthony, Perrier, Helene, Girard, Yves, Nicoll-Griffith, Deborah
Published in Journal of mass spectrometry. (01.06.2006)
Published in Journal of mass spectrometry. (01.06.2006)
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Journal Article
Direct and enantioselective {alpha}-allylation of ketones via singly occupied molecular orbital (SOMO) catalysis
Mastracchio, Anthony, Warkentin, Alexander A, Walji, Abbas M, MacMillan, David W C
Published in Proceedings of the National Academy of Sciences - PNAS (30.11.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (30.11.2010)
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Journal Article
Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma
Plotnik, Joshua P, Richardson, Adam E, Yang, Haopeng, Rojas, Estela, Bontcheva, Velitchka, Dowell, Colleen, Parsons, Sydney, Wilson, Ashley, Ravanmehr, Vida, Will, Christine, Jung, Paul, Zhu, Haizhong, Partha, Sarathy Karunan, Panchal, Sanjay C, Mali, Raghuveer Singh, Kohlhapp, Frederick J, McClure, Ryan A, Ramathal, Cyril Y, George, Mariam D, Jhala, Manisha, Elsen, Nathaniel L, Qiu, Wei, Judge, Russell A, Pan, Chin, Mastracchio, Anthony, Henderson, Jared, Meulbroek, Jonathan A, Green, Michael R, Pappano, William N
Published in Molecular cancer therapeutics (02.07.2024)
Published in Molecular cancer therapeutics (02.07.2024)
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Journal Article
Enabling, Decagram-Scale Synthesis of Macrocyclic MCL‑1 Inhibitor ABBV-467
Brady, Patrick B., Sorensen, Bryan K., Risi, Roberto M., Curtin, Michael L., Mantei, Robert A., Florjancic, Alan S., Mastracchio, Anthony, Ji, Cheng, Kunzer, Aaron R., Lai, Chunqiu, Storer, Gregory E., Chan, Vincent S., Henry, Rodger F., Souers, Andrew J., Michaelides, Michael R., Judd, Andrew S., Hansen, T. Matthew
Published in Journal of organic chemistry (17.11.2023)
Published in Journal of organic chemistry (17.11.2023)
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Journal Article
Corrigendum to “Investigation of biaryl heterocycles as inhibitors of Wee1 kinase” [Bioorg. Med. Chem. Lett. 29 (2019) 1481–1486]
Mastracchio, Anthony, Lai, Chunqiu, Torrent, Maricel, Bromberg, Kenneth, Buchanan, Fritz G., Ferguson, Debra, Bontcheva, Velitchka, Johnson, Eric F., Lasko, Loren, Maag, David, Shoemaker, Alexander R., Penning, Thomas D.
Published in Bioorganic & medicinal chemistry letters (15.02.2020)
Published in Bioorganic & medicinal chemistry letters (15.02.2020)
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Journal Article
Investigation of biaryl heterocycles as inhibitors of Wee1 kinase
Mastracchio, Anthony, Lai, Chunqiu, Torrent, Maricel, Bromberg, Kenneth, Buchanan, Fritz G., Ferguson, Debra, Bontcheva, Velitchka, Johnson, Eric F., Lasko, Loren, Maag, David, Shoemaker, Alexander R., Penning, Thomas D.
Published in Bioorganic & medicinal chemistry letters (15.06.2019)
Published in Bioorganic & medicinal chemistry letters (15.06.2019)
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Journal Article
Collective synthesis of natural products by means of organocascade catalysis
Jones, Spencer B, Simmons, Bryon, Mastracchio, Anthony, MacMillan, David W.C
Published in Nature (London) (14.07.2011)
Published in Nature (London) (14.07.2011)
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Journal Article
Balancing Properties with Carboxylates: A Lead Optimization Campaign for Selective and Orally Active CDK9 Inhibitors
Tong, Yunsong, Florjancic, Alan S, Clark, Rick F, Lai, Chunqiu, Mastracchio, Anthony, Zhu, Gui-dong, Smith, Morey L, Kovar, Peter J, Shaw, Bailin, Albert, Daniel H, Qiu, Wei, Longenecker, Kenton L, Liu, Xiaoqin, Olson, Amanda M, Osterling, Donald J, Tahir, Stephen K, Phillips, Darren C, Leverson, Joel D, Souers, Andrew J, Penning, Thomas D
Published in ACS medicinal chemistry letters (08.07.2021)
Published in ACS medicinal chemistry letters (08.07.2021)
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Journal Article
(2S, 3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl4-oxo-2-(4-[1,2,4]triazolo[1,5-a]pyridin-6-ylphenyl)butanamide: A selective alpha-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Edmondson, Scott D., Mastracchio, Anthony, Mathvink, Robert J., He, Jiafang, Harper, Bart, Park, You-Jung, Beconi, Maria, Di Salvo, Jerry, Eiermann, George J., He, Huaibing, Leiting, Barbara, Leone, Joseph F., Levorse, Dorothy A., Lyons, Kathryn, Patel, Reshma A., Patel, Sangita B., Petrov, Aleksandr, Scapin, Giovanna, Shang, Jackie, Roy, Ranabir Sinha, Smith, Aaron, Wu, Joseph K., Xu, Shiyao, Zhu, Bing, Thornberry, Nancy A., Weber, Ann E.
Published in Journal of medicinal chemistry (15.06.2006)
Published in Journal of medicinal chemistry (15.06.2006)
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Journal Article
Heterocycle fused cyclohexylglycine derivatives as novel dipeptidyl peptidase-IV inhibitors
Mastracchio, A, Parmee, ER, Leiting, B, Marsilio, F, Patel, R, Thornberry, NA, Weber, AE, Edmondson, SD
Published in Heterocycles (01.01.2004)
Published in Heterocycles (01.01.2004)
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Journal Article
(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-a]- pyridin-6-ylphenyl)butanamide: A Selective α-Amino Amide Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes
Edmondson, Scott D, Mastracchio, Anthony, Mathvink, Robert J, He, Jiafang, Harper, Bart, Park, You-Jung, Beconi, Maria, Di Salvo, Jerry, Eiermann, George J, He, Huaibing, Leiting, Barbara, Leone, Joseph F, Levorse, Dorothy A, Lyons, Kathryn, Patel, Reshma A, Patel, Sangita B, Petrov, Aleksandr, Scapin, Giovanna, Shang, Jackie, Roy, Ranabir Sinha, Smith, Aaron, Wu, Joseph K, Xu, Shiyao, Zhu, Bing, Thornberry, Nancy A, Weber, Ann E
Published in Journal of medicinal chemistry (15.06.2006)
Published in Journal of medicinal chemistry (15.06.2006)
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Journal Article
거대환식 MCL-1 저해제 및 이의 용도
JUDD ANDREW, KLING ANDREAS, TESKE JESSE, BRAJE WILFRIED, SONG XIAOHONG, MASTRACCHIO ANTHONY, DOHERTY GEORGE, SOUERS ANDREW, JANTOS KATJA, SULLIVAN GERARD, KUNZER AARON, WANG XILU, PENNING THOMAS, LAI CHUNQIU, TAO ZHI FU, JI CHENG, WENDT MICHAEL, POHLKI FRAUKE
Year of Publication 22.04.2020
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Year of Publication 22.04.2020
Patent
Triazolopiperazine-amides as dipeptidyl peptidase IV inhibitors: Close analogs of JANUVIA™ (sitagliptin phosphate)
Kim, Dooseop, Kowalchick, Jennifer E., Edmondson, Scott D., Mastracchio, Anthony, Xu, Jinyou, Eiermann, George J., Leiting, Barbara, Wu, Joseph K., Pryor, KellyAnn D., Patel, Reshma A., He, Huaibing, Lyons, Kathryn A., Thornberry, Nancy A., Weber, Ann E.
Published in Bioorganic & medicinal chemistry letters (15.06.2007)
Published in Bioorganic & medicinal chemistry letters (15.06.2007)
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