MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM
Casaletto, Jessica B., Geddie, Melissa L., Abu-Yousif, Adnan O., Masson, Kristina, Fulgham, Aaron, Boudot, Antoine, Maiwald, Tim, Kearns, Jeffrey D., Kohli, Neeraj, Su, Stephen, Razlog, Maja, Raue, Andreas, Kalra, Ashish, Håkansson, Maria, Logan, Derek T., Welin, Martin, Chattopadhyay, Shrikanta, Harms, Brian D., Nielsen, Ulrik B., Schoeberl, Birgit, Lugovskoy, Alexey A., MacBeath, Gavin
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2019)
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Journal Article
A novel molecular mechanism of primary resistance to FLT3-kinase inhibitors in AML
Breitenbuecher, Frank, Markova, Boyka, Kasper, Stefan, Carius, Birgit, Stauder, Torsten, Böhmer, Frank D., Masson, Kristina, Rönnstrand, Lars, Huber, Christoph, Kindler, Thomas, Fischer, Thomas
Published in Blood (23.04.2009)
Published in Blood (23.04.2009)
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Journal Article
STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability
Luo, Tuoping, Masson, Kristina, Jaffe, Jacob D, Silkworth, Whitney, Ross, Nathan T, Scherer, Christina A, Scholl, Claudia, Fröhling, Stefan, Carr, Steven A, Stern, Andrew M, Schreiber, Stuart L, Golub, Todd R
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2012)
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Journal Article
Predicting ligand-dependent tumors from multi-dimensional signaling features
Hass, Helge, Masson, Kristina, Wohlgemuth, Sibylle, Paragas, Violette, Allen, John E., Sevecka, Mark, Pace, Emily, Timmer, Jens, Stelling, Joerg, MacBeath, Gavin, Schoeberl, Birgit, Raue, Andreas
Published in NPJ systems biology and applications (20.09.2017)
Published in NPJ systems biology and applications (20.09.2017)
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Journal Article
Protein-tyrosine Phosphatase DEP-1 Controls Receptor Tyrosine Kinase FLT3 Signaling
Arora, Deepika, Stopp, Sabine, Böhmer, Sylvia-Annette, Schons, Julia, Godfrey, Rinesh, Masson, Kristina, Razumovskaya, Elena, Rönnstrand, Lars, Tänzer, Simone, Bauer, Reinhard, Böhmer, Frank-D., Müller, Jörg P.
Published in The Journal of biological chemistry (01.04.2011)
Published in The Journal of biological chemistry (01.04.2011)
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Journal Article
Oncogenic Flt3 receptors display different specificity and kinetics of autophosphorylation
Razumovskaya, Elena, Masson, Kristina, Khan, Rasheed, Bengtsson, Susanne, Rönnstrand, Lars
Published in Experimental hematology (01.08.2009)
Published in Experimental hematology (01.08.2009)
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Journal Article
A role of Gab2 association in Flt3 ITD mediated Stat5 phosphorylation and cell survival
Masson, Kristina, Liu, Tao, Khan, Rasheed, Sun, Jianmin, Rönnstrand, Lars
Published in British journal of haematology (01.07.2009)
Published in British journal of haematology (01.07.2009)
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Journal Article
Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD–induced myeloproliferation
Kharazi, Shabnam, Mead, Adam J., Mansour, Anna, Hultquist, Anne, Böiers, Charlotta, Luc, Sidinh, Buza-Vidas, Natalija, Ma, Zhi, Ferry, Helen, Atkinson, Debbie, Reckzeh, Kristian, Masson, Kristina, Cammenga, Jörg, Rönnstrand, Lars, Arai, Fumio, Suda, Toshio, Nerlov, Claus, Sitnicka, Ewa, Jacobsen, Sten Eirik W.
Published in Blood (29.09.2011)
Published in Blood (29.09.2011)
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Journal Article
Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance
Emdal, Kristina B., Palacio-Escat, Nicolàs, Wigerup, Caroline, Eguchi, Akihiro, Nilsson, Helén, Bekker-Jensen, Dorte B., Rönnstrand, Lars, Kazi, Julhash U., Puissant, Alexandre, Itzykson, Raphaël, Saez-Rodriguez, Julio, Masson, Kristina, Blume-Jensen, Peter, Olsen, Jesper V.
Published in Cell reports (Cambridge) (09.08.2022)
Published in Cell reports (Cambridge) (09.08.2022)
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Journal Article
Direct binding of Cbl to Tyr(568) and Tyr(936) of the stem cell factor receptor/c-Kit is required for ligand-induced ubiquitination, internalization and degradation
Masson, Kristina, Heiss, Elke, Band, Hamid, Rönnstrand, Lars
Published in Biochemical journal (01.10.2006)
Published in Biochemical journal (01.10.2006)
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Journal Article
Abstract 1312: Predicting ligand-dependent tumors from multi-dimensional signaling features
Hass, Helge, Masson, Kristina, Wohlgemuth, Sibylle, Paragas, Violette, Allen, John E., Sevecka, Mark, Pace, Emily, Timmer, Jens, Stelling, Joerg, MacBeath, Gavin, Schoeberl, Birgit, Raue, Andreas
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells
Weïwer, Michel, Spoonamore, James, Wei, Jingqiang, Guichard, Boris, Ross, Nathan T, Masson, Kristina, Silkworth, Whitney, Dandapani, Sivaraman, Palmer, Michelle, Scherer, Christina A, Stern, Andrew M, Schreiber, Stuart L, Munoz, Benito
Published in ACS medicinal chemistry letters (13.12.2012)
Published in ACS medicinal chemistry letters (13.12.2012)
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Journal Article
Abstract C002: Identification of biomarkers predictive of sensitivity to the CHK1/2 inhibitor ACR-368 using high-resolution phosphoproteomics and development of an ACR-368-tailored patient responder identification 3-marker test, ACR-368 OncoSignature
Wigerup, Caroline, Shipitsin, Michail, Murshid, Ayesha, Shi, Lei, Jakobsson, Magnus E., Bekker-Jensen, Dorte, Choudry, Sibgat, Dunyak, James, Proia, David, Olsen, Jesper V., Masson, Kristina, Blume-Jensen, Peter
Published in Molecular cancer therapeutics (01.12.2023)
Published in Molecular cancer therapeutics (01.12.2023)
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Journal Article
Abstract LB-243: The ErbB3-targeting antibody MM-121 (seribantumab) reverses heregulin-driven resistance to multiple chemotherapies on tumor cell growth
Masson, Kristina, Grantcharova, Viara, Burenkova, Olga, Wainszelbaum, Marisa, Iadevaia, Sergio, Adams, Sharlene, Raue, Andreas, Czibere, Akos, Schoeberl, Birgit, MacBeath, Gavin
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Abstract 1690: Mechanistic characterization of MM-131, a bispecific antibody that blocks c-Met signaling through concurrent targeting of EpCAM
Abu-Yousif, Adnan O., Casaletto, Jessica B., Masson, Kristina, Fulgham, Aaron, Geddie, Melissa, Schoeberl, Birgit, Nielsen, Ulrik, MacBeath, Gavin
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Systems biology driving drug development: from design to the clinical testing of the anti-ErbB3 antibody seribantumab (MM-121)
Schoeberl, Birgit, Kudla, Art, Masson, Kristina, Kalra, Ashish, Curley, Michael, Finn, Gregory, Pace, Emily, Harms, Brian, Kim, Jaeyeon, Kearns, Jeff, Fulgham, Aaron, Burenkova, Olga, Grantcharova, Viara, Yarar, Defne, Paragas, Violette, Fitzgerald, Jonathan, Wainszelbaum, Marisa, West, Kip, Mathews, Sara, Nering, Rachel, Adiwijaya, Bambang, Garcia, Gabriela, Kubasek, Bill, Moyo, Victor, Czibere, Akos, Nielsen, Ulrik B, MacBeath, Gavin
Published in NPJ systems biology and applications (01.01.2017)
Published in NPJ systems biology and applications (01.01.2017)
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Journal Article
Abstract 1977: ACR-2316: A potentially first-in-class, potent, selective WEE1/PKMYT1 inhibitor rationally designed for superior single agent activity through synergistic disruption of cell cycle checkpoints
Wigerup, Caroline, Nilsson, Helén, Shi, Lei, Jung, Joon, Baddour-Sousounis, Joelle, Cornelius, Ruban, Lipjankic, Nina, Muralitharan, Uthira, Siino, Valentina, Diez, Ignacio Arribas, Best, Zachary, Pasetto, Martina, Dahlberg, William, Rafiei, Shahrzad, Lombardo, Portia, Jakobsson, Magnus E., Improgo, Reina, Scherer, Christina, van Duzer, John, Proia, David A., Masson, Kristina, Blume-Jensen, Peter
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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