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Published in Proceedings of the National Academy of Sciences - PNAS (28.05.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (28.05.2019)
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Anti-PDGF-B monoclonal antibody reduces liver fibrosis development
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Olinciguat, an Oral sGC Stimulator, Exhibits Diverse Pharmacology Across Preclinical Models of Cardiovascular, Metabolic, Renal, and Inflammatory Disease
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Discovery and SAR of PF-4693627, a potent, selective and orally bioavailable mPGES-1 inhibitor for the potential treatment of inflammation
Arhancet, Graciela B., Walker, Daniel P., Metz, Sue, Fobian, Yvette M., Heasley, Steven E., Carter, Jeffrey S., Springer, John R., Jones, Darin E., Hayes, Michael J., Shaffer, Alexander F., Jerome, Gina M., Baratta, Michael T., Zweifel, Ben, Moore, William M., Masferrer, Jaime L., Vazquez, Michael L.
Published in Bioorganic & medicinal chemistry letters (15.02.2013)
Published in Bioorganic & medicinal chemistry letters (15.02.2013)
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Distinction of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition from cyclooxygenase-2 inhibition in cells using a novel, selective mPGES-1 inhibitor
Mbalaviele, Gabriel, Pauley, Adele M., Shaffer, Alexander F., Zweifel, Ben S., Mathialagan, Sumathy, Mnich, Stephen J., Nemirovskiy, Olga V., Carter, Jeff, Gierse, James K., Wang, Jane L., Vazquez, Michael L., Moore, William M., Masferrer, Jaime L.
Published in Biochemical pharmacology (15.05.2010)
Published in Biochemical pharmacology (15.05.2010)
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Cyclooxygenase-2 Is Overexpressed in Human Cervical Cancer
KULKARNI, Swati, RADER, Janet S, FAN ZHANG, LIAPIS, Helen, KOKI, Alane T, MASFERRER, Jaime L, SUBBARAMAIAH, Kotha, DANNENBERG, Andrew J
Published in Clinical cancer research (01.02.2001)
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Published in Clinical cancer research (01.02.2001)
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Pharmacokinetics, mass balance, tissue distribution, metabolism, and excretion of praliciguat, a clinical‐stage soluble guanylate cyclase stimulator in rats
Banijamali, Ali R., Carvalho, Andrew E., Wakefield, James D., Germano, Peter, Barden, Timothy C., Tobin, Jenny V., Zimmer, Daniel P., Masferrer, Jaime L., Profy, Albert T., Currie, Mark G., Todd Milne, G.
Published in Pharmacology research & perspectives (01.04.2020)
Published in Pharmacology research & perspectives (01.04.2020)
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Comparative Protection against Liver Inflammation and Fibrosis by a Selective Cyclooxygenase-2 Inhibitor and a Nonredox-Type 5-Lipoxygenase Inhibitor
Horrillo, Raquel, Planagumà, Anna, González-Périz, Ana, Ferré, Natàlia, Titos, Esther, Miquel, Rosa, López-Parra, Marta, Masferrer, Jaime L, Arroyo, Vicente, Clària, Joan
Published in The Journal of pharmacology and experimental therapeutics (01.12.2007)
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Synergy between celecoxib and radiotherapy results from inhibition of cyclooxygenase-2-derived prostaglandin E2, a survival factor for tumor and associated vasculature
DAVIS, Thomas W, O'NEAL, Janet M, PAGEL, Mark D, ZWEIFEL, Ben S, MEHTA, Pramod P, HEUVELMAN, Deborah M, MASFERRER, Jaime L
Published in Cancer research (Chicago, Ill.) (2004)
Published in Cancer research (Chicago, Ill.) (2004)
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Stimulation of soluble guanylate cyclase exerts antiinflammatory actions in the liver through a VASP/NF-κB/NLRP3 inflammasome circuit
Flores-Costa, Roger, Duran-Güell, Marta, Casulleras, Mireia, López-Vicario, Cristina, Alcaraz-Quiles, José, Diaz, Alba, Lozano, Juan J., Titos, Esther, Hall, Katherine, Sarno, Renee, Masferrer, Jaime L., Clària, Joan
Published in Proceedings of the National Academy of Sciences - PNAS (10.11.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (10.11.2020)
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Selective Inhibition of Inducible Cyclooxygenase 2 in vivo is Antiinflammatory and Nonulcerogenic
MASFERRER, J. L, ZWEIFEL, B. S, MANNING, P. T, HAUSER, S. D, LEAHY, K. M, SMITH, W. G, ISAKSON, P. C, SEIBERT, K
Published in Proceedings of the National Academy of Sciences - PNAS (12.04.1994)
Published in Proceedings of the National Academy of Sciences - PNAS (12.04.1994)
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Valdecoxib: Assessment of Cyclooxygenase-2 Potency and Selectivity
Gierse, James K, Zhang, Yan, Hood, William F, Walker, Mark C, Trigg, Jennifer S, Maziasz, Timothy J, Koboldt, Carol M, Muhammad, Jerry L, Zweifel, Ben S, Masferrer, Jaime L, Isakson, Peter C, Seibert, Karen
Published in The Journal of pharmacology and experimental therapeutics (01.03.2005)
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Soluble guanylate cyclase stimulator praliciguat attenuates inflammation, fibrosis, and end-organ damage in the Dahl model of cardiorenal failure
Shea, Courtney M, Price, Gavrielle M, Liu, Guang, Sarno, Renee, Buys, Emmanuel S, Currie, Mark G, Masferrer, Jaime L
Published in American journal of physiology. Renal physiology (01.01.2020)
Published in American journal of physiology. Renal physiology (01.01.2020)
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The Cyclooxygenase-2 Inhibitor, Celecoxib, Prevents the Development of Mammary Tumors in HER-2/neu Mice
LANZA-JACOBY, Susan, MILLER, Sheldon, FLYNN, John, GALLATIG, Kathleen, DASKALAKIS, Constantine, MASFERRER, Jaime L, ZWEIFEL, Ben S, SEMBHI, Harjeet, RUSSO, Irma H
Published in Cancer epidemiology, biomarkers & prevention (01.12.2003)
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Published in Cancer epidemiology, biomarkers & prevention (01.12.2003)
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Inhibition of Cyclooxygenase-2 by Celecoxib Reverses Tumor-Induced Wasting
Davis, Thomas W., Zweifel, Ben S., O'Neal, Janet M., Heuvelman, Deborah M., Abegg, Ann L., Hendrich, Todd O., Masferrer, Jaime L.
Published in The Journal of pharmacology and experimental therapeutics (01.03.2004)
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The soluble guanylate cyclase stimulator IW‐1973 prevents inflammation and fibrosis in experimental non‐alcoholic steatohepatitis
Flores‐Costa, Roger, Alcaraz‐Quiles, José, Titos, Esther, López‐Vicario, Cristina, Casulleras, Mireia, Duran‐Güell, Marta, Rius, Bibiana, Diaz, Alba, Hall, Katherine, Shea, Courtney, Sarno, Renee, Currie, Mark, Masferrer, Jaime L, Clària, Joan
Published in British journal of pharmacology (01.03.2018)
Published in British journal of pharmacology (01.03.2018)
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Olinciguat, a stimulator of soluble guanylyl cyclase, attenuates inflammation, vaso‐occlusion and nephropathy in mouse models of sickle cell disease
Tchernychev, Boris, Li, Huihui, Lee, Sung‐Kyun, Gao, Xin, Ramanarasimhaiah, Raghunath, Liu, Guang, Hall, Katherine C., Bernier, Sylvie G., Jones, Juli E., Feil, Susanne, Feil, Robert, Buys, Emmanuel S., Graul, Regina M., Frenette, Paul S., Masferrer, Jaime L.
Published in British journal of pharmacology (01.09.2021)
Published in British journal of pharmacology (01.09.2021)
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Pharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of Disease
Tobin, Jenny V, Zimmer, Daniel P, Shea, Courtney, Germano, Peter, Bernier, Sylvie G, Liu, Guang, Long, Kim, Miyashiro, Joy, Ranganath, Sheila, Jacobson, Sarah, Tang, Kim, Im, G-Yoon Jamie, Sheppeck, 2nd, James, Moore, Joel D, Sykes, Kristine, Wakefield, James, Sarno, Renee, Banijamali, Ali R, Profy, Albert T, Milne, G Todd, Currie, Mark G, Masferrer, Jaime L
Published in The Journal of pharmacology and experimental therapeutics (01.06.2018)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2018)
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SGLT2 inhibition potentiates the cardiovascular, renal, and metabolic effects of sGC stimulation in hypertensive rats with prolonged exposure to high-fat diet
Reverte, Virginia, Rodriguez, Francisca, Oltra, Lidia, Moreno, Juan M, Llinás, María T, Shea, Courtney M, Schwartzkopf, Chad D, Buys, Emmanuel S, Masferrer, Jaime L, Salazar, F Javier
Published in American journal of physiology. Heart and circulatory physiology (01.04.2022)
Published in American journal of physiology. Heart and circulatory physiology (01.04.2022)
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