Identification of the first highly selective inhibitor of human lactate dehydrogenase B
Shibata, Sachio, Sogabe, Satoshi, Miwa, Masanori, Fujimoto, Takuya, Takakura, Nobuyuki, Naotsuka, Akihiko, Kitamura, Shuji, Kawamoto, Tomohiro, Soga, Tomoyoshi
Published in Scientific reports (01.11.2021)
Published in Scientific reports (01.11.2021)
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K-Ras(G12D)-selective inhibitory peptides generated by random peptide T7 phage display technology
Sakamoto, Kotaro, Kamada, Yusuke, Sameshima, Tomoya, Yaguchi, Masahiro, Niida, Ayumu, Sasaki, Shigekazu, Miwa, Masanori, Ohkubo, Shoichi, Sakamoto, Jun-ichi, Kamaura, Masahiro, Cho, Nobuo, Tani, Akiyoshi
Published in Biochemical and biophysical research communications (11.03.2017)
Published in Biochemical and biophysical research communications (11.03.2017)
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Journal Article
A G Protein-coupled Receptor Responsive to Bile Acids
Kawamata, Yuji, Fujii, Ryo, Hosoya, Masaki, Harada, Masataka, Yoshida, Hiromi, Miwa, Masanori, Fukusumi, Shoji, Habata, Yugo, Itoh, Takashi, Shintani, Yasushi, Hinuma, Shuji, Fujisawa, Yukio, Fujino, Masahiko
Published in The Journal of biological chemistry (14.03.2003)
Published in The Journal of biological chemistry (14.03.2003)
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Identification of ligand-selective peptidic ActRIIB-antagonists using phage display technology
Sakamoto, Kotaro, Kanematsu-Yamaki, Yoko, Kamada, Yusuke, Oka, Masahiro, Ohnishi, Toshiyuki, Miwa, Masanori, Asami, Taiji, Inooka, Hiroshi
Published in Biochemistry and biophysics reports (01.09.2017)
Published in Biochemistry and biophysics reports (01.09.2017)
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Journal Article
Phase I study of TP300 in patients with advanced solid tumors with pharmacokinetic, pharmacogenetic and pharmacodynamic analyses
Anthoney, D Alan, Naik, Jay, Macpherson, Iain R J, Crawford, Donna, Hartley, John M, Hartley, Janet A, Saito, Tomohisa, Abe, Masaichi, Jones, Keith, Miwa, Masanori, Twelves, Christopher, Evans, T R J
Published in BMC cancer (21.11.2012)
Published in BMC cancer (21.11.2012)
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Journal Article
The design and synthesis of a new tumor-selective fluoropyrimidine carbamate, Capecitabine
SHIMMA, N, UMEDA, I, KURUMA, I, HORII, I, ISHITSUKA, H, ARASAKI, M, MURASAKI, C, MASUBUCHI, K, KOHCHI, Y, MIWA, M, URA, M, SAWADA, N, TAHARA, H
Published in Bioorganic & medicinal chemistry (01.07.2000)
Published in Bioorganic & medicinal chemistry (01.07.2000)
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Journal Article
Augmentation of the antitumor activity of capecitabine by a tumor selective dihydropyrimidine dehydrogenase inhibitor, RO0094889
Endo, Mika, Miwa, Masanori, Eda, Hiroyuki, Ura, Masako, Tanimura, Hiromi, Ishikawa, Tohru, Miyazaki‐Nose, Taeko, Hattori, Kazuo, Shimma, Nobuo, Yamada‐Okabe, Hisafumi, Ishitsuka, Hideo
Published in International journal of cancer (20.09.2003)
Published in International journal of cancer (20.09.2003)
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Journal Article
Discovery of a novel prolyl-tRNA synthetase inhibitor and elucidation of its binding mode to the ATP site in complex with l-proline
Adachi, Ryutaro, Okada, Kengo, Skene, Robert, Ogawa, Kazumasa, Miwa, Masanori, Tsuchinaga, Kazuhiro, Ohkubo, Shoichi, Henta, Tsutomu, Kawamoto, Tomohiro
Published in Biochemical and biophysical research communications (24.06.2017)
Published in Biochemical and biophysical research communications (24.06.2017)
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Journal Article
Identification of α‑Synuclein Proaggregator: Rapid Synthesis and Streamlining RT-QuIC Assays in Parkinson’s Disease
Takada, Fumito, Kasahara, Takahito, Otake, Kentaro, Maru, Takamitsu, Miwa, Masanori, Muto, Kei, Sasaki, Minoru, Hirozane, Yoshihiko, Yoshikawa, Masato, Yamaguchi, Junichiro
Published in ACS medicinal chemistry letters (08.09.2022)
Published in ACS medicinal chemistry letters (08.09.2022)
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Journal Article
Crystal Structure of a Human K‑Ras G12D Mutant in Complex with GDP and the Cyclic Inhibitory Peptide KRpep-2d
Sogabe, Satoshi, Kamada, Yusuke, Miwa, Masanori, Niida, Ayumu, Sameshima, Tomoya, Kamaura, Masahiro, Yonemori, Kazuko, Sasaki, Shigekazu, Sakamoto, Jun-ichi, Sakamoto, Kotaro
Published in ACS medicinal chemistry letters (13.07.2017)
Published in ACS medicinal chemistry letters (13.07.2017)
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Journal Article
Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2
Iwatani-Yoshihara, Misa, Ito, Masahiro, Klein, Michael G, Yamamoto, Takeshi, Yonemori, Kazuko, Tanaka, Toshio, Miwa, Masanori, Morishita, Daisuke, Endo, Satoshi, Tjhen, Richard, Qin, Ling, Nakanishi, Atsushi, Maezaki, Hironobu, Kawamoto, Tomohiro
Published in Journal of medicinal chemistry (13.07.2017)
Published in Journal of medicinal chemistry (13.07.2017)
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Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent
Isshiki, Yoshiaki, Kohchi, Yasunori, Iikura, Hitoshi, Matsubara, Yasuaki, Asoh, Kohsuke, Murata, Takeshi, Kohchi, Masami, Mizuguchi, Eisaku, Tsujii, Shinji, Hattori, Kazuo, Miura, Takaaki, Yoshimura, Yasushi, Aida, Satoshi, Miwa, Masanori, Saitoh, Ryoichi, Murao, Naoaki, Okabe, Hisafumi, Belunis, Charles, Janson, Cheryl, Lukacs, Christine, Schück, Verena, Shimma, Nobuo
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
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Journal Article
Comparative Antitumor Activity and Intestinal Toxicity of 5′‐Deoxy‐5‐fluorouridine and Its Prodrug Trimethoxybenzoyl‐5′‐deoxy‐5‐fluorocytidine
Ninomiya, Yasuyuki, Miwa, Masanori, Eda, Hiroyuki, Sahara, Hiroshi, Fujimoto, Kaori, Ishida, Masako, Umeda, Isao, Yokose, Kazuteru, Ishitsuka, Hideo
Published in Cancer science (01.02.1990)
Published in Cancer science (01.02.1990)
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Journal Article
water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts
Endo, Mika, Miwa, Masanori, Ura, Masako, Tanimura, Hiromi, Taniguchi, Kenji, Miyazaki, Yoko, Ohwada, Jun, Tsukazaki, Masao, Niizuma, Satoshi, Murata, Takeshi, Ozawa, Sawako, Suda, Hitomi, Ogawa, Kotaro, Nanba, Eitaro, Nagao, Shunsuke, Shimma, Nobuo, Yamada-Okabe, Hisafumi
Published in Cancer chemotherapy and pharmacology (2010)
Published in Cancer chemotherapy and pharmacology (2010)
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Journal Article
A water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts
ENDO, Mika, MIWA, Masanori, OZAWA, Sawako, SUDA, Hitomi, OGAWA, Kotaro, NANBA, Eitaro, NAGAO, Shunsuke, SHIMMA, Nobuo, YAMADA-OKABE, Hisafumi, URA, Masako, TANIMURA, Hiromi, TANIGUCHI, Kenji, MIYAZAKI, Yoko, OHWADA, Jun, TSUKAZAKI, Masao, NIIZUMA, Satoshi, MURATA, Takeshi
Published in Cancer chemotherapy and pharmacology (2010)
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Published in Cancer chemotherapy and pharmacology (2010)
Journal Article
Comparative studies on the antitumor and immunosuppressive effects of the new fluorouracil derivative N4-trimethoxybenzoyl-5'-deoxy-5-fluorocytidine and its parent drug 5'-deoxy-5-fluorouridine
Miwa, M, Ishikawa, T, Eda, H, Ryu, M, Fujimoto, K, Ninomiya, Y, Umeda, I, Yokose, K, Ishitsuka, H
Published in Chemical & pharmaceutical bulletin (1990)
Published in Chemical & pharmaceutical bulletin (1990)
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Journal Article
Design and synthesis of novel prodrugs of 2′-deoxy-2′-methylidenecytidine activated by membrane dipeptidase overexpressed in tumor tissues
Kohchi, Yasunori, Hattori, Kazuo, Oikawa, Nobuhiro, Mizuguchi, Eisaku, Isshiki, Yoshiaki, Aso, Kohsuke, Yoshinari, Kiyoshi, Shirai, Haruyoshi, Miwa, Masanori, Inagaki, Yukiko, Ura, Masako, Ogawa, Kotaroh, Okabe, Hisafumi, Ishitsuka, Hideo, Shimma, Nobuo
Published in Bioorganic & medicinal chemistry letters (15.04.2007)
Published in Bioorganic & medicinal chemistry letters (15.04.2007)
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Journal Article
Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine
Hattori, Kazuo, Kohchi, Yasunori, Oikawa, Nobuhiro, Suda, Hitomi, Ura, Masako, Ishikawa, Tohru, Miwa, Masanori, Endoh, Mika, Eda, Hiroyuki, Tanimura, Hiromi, Kawashima, Akira, Horii, Ikuo, Ishitsuka, Hideo, Shimma, Nobuo
Published in Bioorganic & medicinal chemistry letters (10.03.2003)
Published in Bioorganic & medicinal chemistry letters (10.03.2003)
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