Selective inhibition of TGFβ1 activation overcomes primary resistance to checkpoint blockade therapy by altering tumor immune landscape
Martin, Constance J, Datta, Abhishek, Littlefield, Christopher, Kalra, Ashish, Chapron, Christopher, Wawersik, Stefan, Dagbay, Kevin B, Brueckner, Christopher T, Nikiforov, Anastasia, Danehy, Jr, Francis T, Streich, Jr, Frederick C, Boston, Christopher, Simpson, Allison, Jackson, Justin W, Lin, Susan, Danek, Nicole, Faucette, Ryan R, Raman, Pichai, Capili, Allan D, Buckler, Alan, Carven, Gregory J, Schürpf, Thomas
Published in Science translational medicine (25.03.2020)
Published in Science translational medicine (25.03.2020)
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Journal Article
Macrophages clean up: efferocytosis and microbial control
Martin, Constance J, Peters, Kristen N, Behar, Samuel M
Published in Current opinion in microbiology (01.02.2014)
Published in Current opinion in microbiology (01.02.2014)
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Journal Article
Efferocytosis Is an Innate Antibacterial Mechanism
Martin, Constance J., Booty, Matthew G., Rosebrock, Tracy R., Nunes-Alves, Cláudio, Desjardins, Danielle M., Keren, Iris, Fortune, Sarah M., Remold, Heinz G., Behar, Samuel M.
Published in Cell host & microbe (13.09.2012)
Published in Cell host & microbe (13.09.2012)
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Journal Article
Concurrent infection with Mycobacterium tuberculosis confers robust protection against secondary infection in macaques
Cadena, Anthony M, Hopkins, Forrest F, Maiello, Pauline, Carey, Allison F, Wong, Eileen A, Martin, Constance J, Gideon, Hannah P, DiFazio, Robert M, Andersen, Peter, Lin, Philana Ling, Fortune, Sarah M, Flynn, JoAnne L
Published in PLoS pathogens (01.10.2018)
Published in PLoS pathogens (01.10.2018)
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Journal Article
Digitally Barcoding Mycobacterium tuberculosis Reveals In Vivo Infection Dynamics in the Macaque Model of Tuberculosis
Martin, Constance J, Cadena, Anthony M, Leung, Vivian W, Lin, Philana Ling, Maiello, Pauline, Hicks, Nathan, Chase, Michael R, Flynn, JoAnne L, Fortune, Sarah M
Published in mBio (09.05.2017)
Published in mBio (09.05.2017)
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Journal Article
Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis
Bryson, Bryan D., Rosebrock, Tracy R., Tafesse, Fikadu G., Itoh, Christopher Y., Nibasumba, Armel, Babunovic, Gregory H., Corleis, Bjorn, Martin, Constance, Keegan, Caroline, Andrade, Priscila, Realegeno, Susan, Kwon, Douglas, Modlin, Robert L., Fortune, Sarah M.
Published in Nature communications (27.05.2019)
Published in Nature communications (27.05.2019)
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Journal Article
Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection
Nunes-Alves, Cláudio, Booty, Matthew G, Carpenter, Stephen M, Rothchild, Alissa C, Martin, Constance J, Desjardins, Danielle, Steblenko, Katherine, Kløverpris, Henrik N, Madansein, Rajhmun, Ramsuran, Duran, Leslie, Alasdair, Correia-Neves, Margarida, Behar, Samuel M
Published in PLoS pathogens (01.05.2015)
Published in PLoS pathogens (01.05.2015)
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Journal Article
A bug’s life in the granuloma
Martin, Constance J., Carey, Allison F., Fortune, Sarah M.
Published in Seminars in Immunopathology (01.03.2016)
Published in Seminars in Immunopathology (01.03.2016)
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Journal Article
Book Review
An antibody that inhibits TGF-β1 release from latent extracellular matrix complexes attenuates the progression of renal fibrosis
Jackson, Justin W, Frederick C Streich, Jr, Pal, Ajai, Coricor, George, Boston, Chris, Brueckner, Christopher T, Canonico, Kaleigh, Chapron, Christopher, Cote, Shaun, Dagbay, Kevin B, Danehy, Jr, Francis T, Kavosi, Mania, Kumar, Sandeep, Lin, Susan, Littlefield, Christopher, Looby, Kailyn, Manohar, Rohan, Martin, Constance J, Wood, Marcie, Zawadzka, Agatha, Wawersik, Stefan, Nicholls, Samantha B, Datta, Abhishek, Buckler, Alan, Schürpf, Thomas, Carven, Gregory J, Qatanani, Mohammed, Fogel, Adam I
Published in Science signaling (09.07.2024)
Published in Science signaling (09.07.2024)
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Journal Article
Nonclinical Development of SRK-181: An Anti-Latent TGFβ1 Monoclonal Antibody for the Treatment of Locally Advanced or Metastatic Solid Tumors
Welsh, Brian T., Faucette, Ryan, Bilic, Sanela, Martin, Constance J., Schürpf, Thomas, Chen, David, Nicholls, Samantha, Lansita, Janice, Kalra, Ashish
Published in International journal of toxicology (01.05.2021)
Published in International journal of toxicology (01.05.2021)
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Journal Article
Requirement for Invariant Chain in Macrophages for Mycobacterium tuberculosis Replication and CD1d Antigen Presentation
Sillé, Fenna C M, Martin, Constance, Jayaraman, Pushpa, Rothchild, Alissa, Fortune, Sarah, Besra, Gurdyal S, Behar, Samuel M, Boes, Marianne
Published in Infection and Immunity (01.08.2011)
Published in Infection and Immunity (01.08.2011)
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Journal Article
Treatments for the Prevention and Management of Suicide: A Systematic Review
D'Anci, Kristen E, Uhl, Stacey, Giradi, Gina, Martin, Constance
Published in Annals of internal medicine (03.09.2019)
Published in Annals of internal medicine (03.09.2019)
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Journal Article
A Functional Role for Antibodies in Tuberculosis
Lu, Lenette L., Chung, Amy W., Rosebrock, Tracy R., Ghebremichael, Musie, Yu, Wen Han, Grace, Patricia S., Schoen, Matthew K., Tafesse, Fikadu, Martin, Constance, Leung, Vivian, Mahan, Alison E., Sips, Magdalena, Kumar, Manu P., Tedesco, Jacquelynne, Robinson, Hannah, Tkachenko, Elizabeth, Draghi, Monia, Freedberg, Katherine J., Streeck, Hendrik, Suscovich, Todd J., Lauffenburger, Douglas A., Restrepo, Blanca I., Day, Cheryl, Fortune, Sarah M., Alter, Galit
Published in Cell (06.10.2016)
Published in Cell (06.10.2016)
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Journal Article
Abstract 4090: Defeating primary checkpoint resistance: SRTβ1-Ab3 is a first-in-class, fully human antibody that renders resistant tumors sensitive to anti-PD-1
Schürpf, Thomas, Martin, Constance J., Littlefield, Christopher, Chapron, Christopher, Wawersik, Stefan, Kalra, Ashish, Simpson, Allison, Danehy, Francis, Boston, Christopher, Nikiforov, Anastasia, Lin, Susan, Jackson, Justin, Carven, Gregory J., Buckler, Alan, Datta, Abhishek
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article