Evaluation of engineered AAV capsids for hepatic factor IX gene transfer in murine and canine models
Markusic, David M, Nichols, Timothy C, Merricks, Elizabeth P, Palaschak, Brett, Zolotukhin, Irene, Marsic, Damien, Zolotukhin, Sergei, Srivastava, Arun, Herzog, Roland W
Published in Journal of translational medicine (01.05.2017)
Published in Journal of translational medicine (01.05.2017)
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Journal Article
Engineering and In Vitro Selection of a Novel AAV3B Variant with High Hepatocyte Tropism and Reduced Seroreactivity
Biswas, Moanaro, Marsic, Damien, Li, Ning, Zou, Chenhui, Gonzalez-Aseguinolaza, Gloria, Zolotukhin, Irene, Kumar, Sandeep R.P., Rana, Jyoti, Butterfield, John S.S., Kondratov, Oleksandr, de Jong, Ype P., Herzog, Roland W., Zolotukhin, Sergei
Published in Molecular therapy. Methods & clinical development (11.12.2020)
Published in Molecular therapy. Methods & clinical development (11.12.2020)
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Journal Article
An Immune-Competent Murine Model to Study Elimination of AAV-Transduced Hepatocytes by Capsid-Specific CD8 + T Cells
Palaschak, Brett, Marsic, Damien, Herzog, Roland W, Zolotukhin, Sergei, Markusic, David M
Published in Molecular therapy. Methods & clinical development (16.06.2017)
Published in Molecular therapy. Methods & clinical development (16.06.2017)
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Journal Article
Thermococcus thioreducens sp. nov., a novel hyperthermophilic, obligately sulfur-reducing archaeon from a deep-sea hydrothermal vent
Pikuta, Elena V, Marsic, Damien, Itoh, Takashi, Bej, Asim K, Tang, Jane, Whitman, William B, Ng, Joseph D, Garriott, Owen K, Hoover, Richard B
Published in International journal of systematic and evolutionary microbiology (01.07.2007)
Published in International journal of systematic and evolutionary microbiology (01.07.2007)
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Journal Article
PCR-based gene synthesis to produce recombinant proteins for crystallization
Marsic, Damien, Hughes, Ronny C, Byrne-Steele, Miranda L, Ng, Joseph D
Published in BMC biotechnology (29.04.2008)
Published in BMC biotechnology (29.04.2008)
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Journal Article
Direct Head-to-Head Evaluation of Recombinant Adeno-associated Viral Vectors Manufactured in Human versus Insect Cells
Kondratov, Oleksandr, Marsic, Damien, Crosson, Sean M., Mendez-Gomez, Hector R., Moskalenko, Oleksandr, Mietzsch, Mario, Heilbronn, Regine, Allison, Jonathan R., Green, Kari B., Agbandje-McKenna, Mavis, Zolotukhin, Sergei
Published in Molecular therapy (06.12.2017)
Published in Molecular therapy (06.12.2017)
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Journal Article
Characterization of a Bioengineered AAV3B Capsid Variant with Enhanced Hepatocyte Tropism and Immune Evasion
Rana, Jyoti, Marsic, Damien, Zou, Chenhui, Muñoz-Melero, Maite, Li, Xin, Kondratov, Oleksandr, Li, Ning, de Jong, Ype P, Zolotukhin, Sergei, Biswas, Moanaro
Published in Human gene therapy (01.04.2023)
Published in Human gene therapy (01.04.2023)
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Journal Article
Vector Design Tour de Force: Integrating Combinatorial and Rational Approaches to Derive Novel Adeno-associated Virus Variants
Marsic, Damien, Govindasamy, Lakshmanan, Currlin, Seth, Markusic, David M, Tseng, Yu-Shan, Herzog, Roland W, Agbandje-McKenna, Mavis, Zolotukhin, Sergei
Published in Molecular therapy (01.11.2014)
Published in Molecular therapy (01.11.2014)
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Journal Article
Intravitreal injection of a rationally designed AAV capsid library in non-human primate identifies variants with enhanced retinal transduction and neutralizing antibody evasion
Kellish, Patrick C., Marsic, Damien, Crosson, Sean M., Choudhury, Shreyasi, Scalabrino, Miranda L., Strang, Christianne E., Hill, Julie, McCullough, K. Tyler, Peterson, James J., Fajardo, Diego, Gupte, Siddhant, Makal, Victoria, Kondratov, Oleksandr, Kondratova, Liudmyla, Iyer, Siva, Witherspoon, C. Douglas, Gamlin, Paul D., Zolotukhin, Sergei, Boye, Sanford L., Boye, Shannon E.
Published in Molecular therapy (06.12.2023)
Published in Molecular therapy (06.12.2023)
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Journal Article
Biodistribution and safety of a single rAAV3B-AAT vector for silencing and replacement of alpha-1 antitrypsin in Cynomolgus macaques
Blackwood, Meghan, Gruntman, Alisha M., Tang, Qiushi, Pires-Ferreira, Debora, Reil, Darcy, Kondratov, Oleksandr, Marsic, Damien, Zolotukhin, Sergei, Gernoux, Gwladys, Keeler, Allison M., Mueller, Christian, Flotte, Terence R.
Published in Molecular therapy. Methods & clinical development (14.03.2024)
Published in Molecular therapy. Methods & clinical development (14.03.2024)
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Journal Article
723. AAV Mediated Cancer Targeting: Systemic Trafficking to Tumor Is More Important Than Vector Tumor Cell Interaction
Lu, Yuan, Marsic, Damien, Ling, Chen, Guijario, Maria V., Levings, Padraic P., Palmer, Glyn D., Dacanay, Anthony, Watson-Levings, Rachael S., Hyddmark, Viktoria, White, Margaret E., Zolotukhin, Sergei, Ghivizzani, Steven C.
Published in Molecular therapy (01.05.2016)
Published in Molecular therapy (01.05.2016)
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Journal Article
Proteocatella sphenisci gen. nov., sp. nov., a psychrotolerant, spore-forming anaerobe isolated from penguin guano
Pikuta, Elena V, Hoover, Richard B, Marsic, Damien, Whitman, William B, Lupa, Boguslaw, Tang, Jane, Krader, Paul
Published in International journal of systematic and evolutionary microbiology (01.09.2009)
Published in International journal of systematic and evolutionary microbiology (01.09.2009)
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Journal Article
Spirochaeta dissipatitropha sp. nov., an alkaliphilic, obligately anaerobic bacterium, and emended description of the genus Spirochaeta Ehrenberg 1835
Pikuta, Elena V, Hoover, Richard B, Bej, Asim K, Marsic, Damien, Whitman, William B, Krader, Paul
Published in International journal of systematic and evolutionary microbiology (01.07.2009)
Published in International journal of systematic and evolutionary microbiology (01.07.2009)
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Journal Article