Search Results - "MARK KIRBY" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice

Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice

by Parks, Brian W., Nam, Elizabeth, Org, Elin, Kostem, Emrah, Norheim, Frode, Hui, Simon T., Pan, Calvin, Civelek, Mete, Rau, Christoph D., Bennett, Brian J., Mehrabian, Margarete, Ursell, Luke K., He, Aiqing, Castellani, Lawrence W., Zinker, Bradley, Kirby, Mark, Drake, Thomas A., Drevon, Christian A., Knight, Rob, Gargalovic, Peter, Kirchgessner, Todd, Eskin, Eleazar, Lusis, Aldons J.
Published in Cell metabolism (08.01.2013)

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Accidental spills at sea – Risk, impact, mitigation and the need for co-ordinated post-incident monitoring

Accidental spills at sea – Risk, impact, mitigation and the need for co-ordinated post-incident monitoring

by Kirby, Mark F., Law, Robin J.
Published in Marine pollution bulletin (01.06.2010)

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Journal Article

Qualification of oil-spill treatment products – Adopting the Baffled Flask Test for testing of dispersant efficacy in the UK

Qualification of oil-spill treatment products – Adopting the Baffled Flask Test for testing of dispersant efficacy in the UK

by Sühring, Roxana, Smith, Andy, Emerson, Heather, Doran, Denise, Mellor, Phil, Kirby, Mark F., Christie, Bernard
Published in Marine pollution bulletin (01.04.2018)

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Discovery and Preclinical Profile of Saxagliptin (BMS-477118): A Highly Potent, Long-Acting, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

by Augeri, David J, Robl, Jeffrey A, Betebenner, David A, Magnin, David R, Khanna, Ashish, Robertson, James G, Wang, Aiying, Simpkins, Ligaya M, Taunk, Prakash, Huang, Qi, Han, Song-Ping, Abboa-Offei, Benoni, Cap, Michael, Xin, Li, Tao, Li, Tozzo, Effie, Welzel, Gustav E, Egan, Donald M, Marcinkeviciene, Jovita, Chang, Shu Y, Biller, Scott A, Kirby, Mark S, Parker, Rex A, Hamann, Lawrence G
Published in Journal of medicinal chemistry (28.07.2005)

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Inhibitor selectivity in the clinical application of dipeptidyl peptidase-4 inhibition

Inhibitor selectivity in the clinical application of dipeptidyl peptidase-4 inhibition

by KIRBY, Mark, YU, Denise M. T, O'CONNOR, Stephen P, GORRELL, Mark D
Published in Clinical science (1979) (01.01.2010)

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The use of chemical dispersants to combat oil spills at sea: A review of practice and research needs in Europe

The use of chemical dispersants to combat oil spills at sea: A review of practice and research needs in Europe

by Chapman, Helen, Purnell, Karen, Law, Robin J., Kirby, Mark F.
Published in Marine pollution bulletin (01.07.2007)

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A standardised approach to the environmental risk assessment of potentially polluting wrecks

A standardised approach to the environmental risk assessment of potentially polluting wrecks

by Goodsir, Freya, Lonsdale, Jemma A., Mitchell, Peter J., Suehring, Roxana, Farcas, Adrian, Whomersley, Paul, Brant, Jan L., Clarke, Charlotte, Kirby, Mark F., Skelhorn, Matthew, Hill, Polly G.
Published in Marine pollution bulletin (01.05.2019)

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The principles of effective post-spill environmental monitoring in marine environments and their application to preparedness assessment

The principles of effective post-spill environmental monitoring in marine environments and their application to preparedness assessment

by Kirby, Mark F., Gioia, Rosalinda, Law, Robin J.
Published in Marine pollution bulletin (15.05.2014)

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Foveal Anatomic Associations with the Secondary Peak and the Slope of the Macular Pigment Spatial Profile

by Kirby, Mark L, Galea, Martin, Loane, Edward, Stack, Jim, Beatty, Stephen, Nolan, John M
Published in Investigative ophthalmology & visual science (01.03.2009)

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Involvement of DPP‐IV catalytic residues in enzyme–saxagliptin complex formation

Involvement of DPP‐IV catalytic residues in enzyme–saxagliptin complex formation

by Metzler, William J., Yanchunas, Joseph, Weigelt, Carolyn, Kish, Kevin, Klei, Herbert E., Xie, Dianlin, Zhang, Yaqun, Corbett, Martin, Tamura, James K., He, Bin, Hamann, Lawrence G., Kirby, Mark S., Marcinkeviciene, Jovita
Published in Protein science (01.02.2008)

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A central dip in the macular pigment spatial profile is associated with age and smoking

by Kirby, Mark L, Beatty, Stephen, Loane, Edward, Akkali, Mukunda C, Connolly, Eithne E, Stack, Jim, Nolan, John M
Published in Investigative ophthalmology & visual science (01.12.2010)

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Synthesis and SAR of azolopyrimidines as potent and selective dipeptidyl peptidase-4 (DPP4) inhibitors for type 2 diabetes

Synthesis and SAR of azolopyrimidines as potent and selective dipeptidyl peptidase-4 (DPP4) inhibitors for type 2 diabetes

by Brigance, Robert P., Meng, Wei, Fura, Aberra, Harrity, Thomas, Wang, Aiying, Zahler, Robert, Kirby, Mark S., Hamann, Lawrence G.
Published in Bioorganic & medicinal chemistry letters (01.08.2010)

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Potency, selectivity and prolonged binding of saxagliptin to DPP4: maintenance of DPP4 inhibition by saxagliptin in vitro and ex vivo when compared to a rapidly-dissociating DPP4 inhibitor

Potency, selectivity and prolonged binding of saxagliptin to DPP4: maintenance of DPP4 inhibition by saxagliptin in vitro and ex vivo when compared to a rapidly-dissociating DPP4 inhibitor

by Wang, Aiying, Dorso, Charles, Kopcho, Lisa, Locke, Gregory, Langish, Robert, Harstad, Eric, Shipkova, Petia, Marcinkeviciene, Jovita, Hamann, Lawrence, Kirby, Mark S
Published in BMC pharmacology (04.04.2012)

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Pharmacokinetics of the Dipeptidyl Peptidase 4 Inhibitor Saxagliptin in Rats, Dogs, and Monkeys and Clinical Projections

Pharmacokinetics of the Dipeptidyl Peptidase 4 Inhibitor Saxagliptin in Rats, Dogs, and Monkeys and Clinical Projections

by FURA, Aberra, KHANNA, Ashish, HUMPHREYS, W. Griffith, KIRBY, Mark, VYAS, Viral, KOPLOWITZ, Barry, CHANG, Shu-Ying, CAPORUSCIO, Christian, BOULTON, David W, CHRISTOPHER, Lisa J, CHADWICK, Kristina D, HAMANN, Lawrence G
Published in Drug metabolism and disposition (01.06.2009)

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Substitution of hazardous offshore chemicals in UK waters: an evaluation of their use and discharge from 2000 to 2012

Substitution of hazardous offshore chemicals in UK waters: an evaluation of their use and discharge from 2000 to 2012

by La Védrine, Maximillian A.G., Sheahan, David A., Gioia, Rosalinda, Rowles, Bob, Kroeger, Silke, Phillips, Claire, Kirby, Mark F.
Published in Journal of cleaner production (15.01.2015)

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Towards a scheme of toxic equivalency factors (TEFs) for the acute toxicity of PAHs in sediment

Towards a scheme of toxic equivalency factors (TEFs) for the acute toxicity of PAHs in sediment

by Fisher, Tom T., Law, Robin J., Rumney, Heather S., Kirby, Mark F., Kelly, Carole
Published in Ecotoxicology and environmental safety (01.11.2011)

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A circulating microRNA signature as noninvasive diagnostic and prognostic biomarkers for nonalcoholic steatohepatitis

A circulating microRNA signature as noninvasive diagnostic and prognostic biomarkers for nonalcoholic steatohepatitis

by Liu, Jie, Xiao, Yue, Wu, Xikun, Jiang, Lichun, Yang, Shurong, Ding, Zhiming, Fang, Zhuo, Hua, Haiqing, Kirby, Mark Stephen, Shou, Jianyong
Published in BMC genomics (09.03.2018)

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Substituted piperidinyl glycinyl 2-cyano-4,5-methano pyrrolidines as potent and stable dipeptidyl peptidase IV inhibitors

Substituted piperidinyl glycinyl 2-cyano-4,5-methano pyrrolidines as potent and stable dipeptidyl peptidase IV inhibitors

by Zhao, Guohua, Kwon, Chet, Wang, Aiying, Robertson, James G., Marcinkeviciene, Jovita, Parker, Rex A., Kirby, Mark S., Hamann, Lawrence G.
Published in Bioorganic & medicinal chemistry letters (15.03.2013)

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Polycyclic aromatic hydrocarbons in fish from St Helena, South Atlantic, in relation to an historic wreck

Polycyclic aromatic hydrocarbons in fish from St Helena, South Atlantic, in relation to an historic wreck

by Rumney, Heather S., Potter, Kerry, Mellor, Philip K., Brant, Jan, Whomersley, Paul, Shaw, Stephen, Barry, Jon, Kirby, Mark F., Law, Robin J.
Published in Marine pollution bulletin (15.12.2014)

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Optimization of Activity, Selectivity, and Liability Profiles in 5‑Oxopyrrolopyridine DPP4 Inhibitors Leading to Clinical Candidate (Sa)‑2-(3-(Aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo‑5H‑pyrrolo[3,4‑b]pyridin-6(7H)‑yl)‑N,N‑dimethylacetamide (BMS-767778)

Optimization of Activity, Selectivity, and Liability Profiles in 5‑Oxopyrrolopyridine DPP4 Inhibitors Leading to Clinical Candidate (Sa)‑2-(3-(Aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo‑5H‑pyrrolo[3,4‑b]pyridin-6(7H)‑yl)‑N,N‑dimethylacetamide (BMS-767778)

by Devasthale, Pratik, Wang, Ying, Wang, Wei, Fevig, John, Feng, JianXin, Wang, Aiying, Harrity, Tom, Egan, Don, Morgan, Nathan, Cap, Michael, Fura, Aberra, Klei, Herbert E, Kish, Kevin, Weigelt, Carolyn, Sun, Lucy, Levesque, Paul, Moulin, Frederic, Li, Yi-Xin, Zahler, Robert, Kirby, Mark S, Hamann, Lawrence G
Published in Journal of medicinal chemistry (26.09.2013)

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