The NMDA receptor as a target for cognitive enhancement
Collingridge, Graham L., Volianskis, Arturas, Bannister, Neil, France, Grace, Hanna, Lydia, Mercier, Marion, Tidball, Patrick, Fang, Guangyu, Irvine, Mark W., Costa, Blaise M., Monaghan, Daniel T., Bortolotto, Zuner A., Molnár, Elek, Lodge, David, Jane, David E.
Published in Neuropharmacology (01.01.2013)
Published in Neuropharmacology (01.01.2013)
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Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors
Wang, Jue Xiang, Irvine, Mark W, Burnell, Erica S, Sapkota, Kiran, Thatcher, Robert J, Li, Minjun, Simorowski, Noriko, Volianskis, Arturas, Collingridge, Graham L, Monaghan, Daniel T, Jane, David E, Furukawa, Hiro
Published in Nature communications (22.01.2020)
Published in Nature communications (22.01.2020)
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Pharmacological characterization of a novel negative allosteric modulator of NMDA receptors, UBP792
Sapkota, Kiran, Burnell, Erica S., Irvine, Mark W., Fang, Guangyu, Gawande, Dinesh Y., Dravid, Shashank M., Jane, David E., Monaghan, Daniel T.
Published in Neuropharmacology (15.12.2021)
Published in Neuropharmacology (15.12.2021)
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Different NMDA receptor subtypes mediate induction of long‐term potentiation and two forms of short‐term potentiation at CA1 synapses in rat hippocampus in vitro
Volianskis, Arturas, Bannister, Neil, Collett, Valerie J., Irvine, Mark W., Monaghan, Daniel T., Fitzjohn, Stephen M., Jensen, Morten S., Jane, David E., Collingridge, Graham L.
Published in The Journal of physiology (01.02.2013)
Published in The Journal of physiology (01.02.2013)
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Journal Article
Multiple roles of GluN2B-containing NMDA receptors in synaptic plasticity in juvenile hippocampus
France, Grace, Fernández-Fernández, Diego, Burnell, Erica S., Irvine, Mark W., Monaghan, Daniel T., Jane, David E., Bortolotto, Zuner A., Collingridge, Graham L., Volianskis, Arturas
Published in Neuropharmacology (01.01.2017)
Published in Neuropharmacology (01.01.2017)
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A novel family of negative and positive allosteric modulators of NMDA receptors
Costa, Blaise Mathias, Irvine, Mark W, Fang, Guangyu, Eaves, Richard J, Mayo-Martin, Marie Belen, Skifter, Donald A, Jane, David E, Monaghan, Daniel T
Published in The Journal of pharmacology and experimental therapeutics (01.12.2010)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2010)
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Investigation of the structural requirements for N-methyl-D-aspartate receptor positive and negative allosteric modulators based on 2-naphthoic acid
Irvine, Mark W., Fang, Guangyu, Sapkota, Kiran, Burnell, Erica S., Volianskis, Arturas, Costa, Blaise M., Culley, Georgia, Collingridge, Graham L., Monaghan, Daniel T., Jane, David E.
Published in European journal of medicinal chemistry (15.02.2019)
Published in European journal of medicinal chemistry (15.02.2019)
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The Startle Disease Mutation E103K Impairs Activation of Human Homomeric α1 Glycine Receptors by Disrupting an Intersubunit Salt Bridge across the Agonist Binding Site
Safar, Fatemah, Hurdiss, Elliot, Erotocritou, Marios, Greiner, Timo, Lape, Remigijus, Irvine, Mark W., Fang, Guangyu, Jane, David, Yu, Rilei, Dämgen, Marc A., Biggin, Philip C., Sivilotti, Lucia G.
Published in The Journal of biological chemistry (24.03.2017)
Published in The Journal of biological chemistry (24.03.2017)
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Mechanism and properties of positive allosteric modulation of N-methyl-d-aspartate receptors by 6-alkyl 2-naphthoic acid derivatives
Sapkota, Kiran, Irvine, Mark W., Fang, Guangyu, Burnell, Erica S., Bannister, Neil, Volianskis, Arturas, Culley, Georgia R., Dravid, Shashank M., Collingridge, Graham L., Jane, David E., Monaghan, Daniel T.
Published in Neuropharmacology (01.10.2017)
Published in Neuropharmacology (01.10.2017)
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Journal Article
Structure-activity relationships for allosteric NMDA receptor inhibitors based on 2-naphthoic acid
Costa, Blaise Mathias, Irvine, Mark W., Fang, Guangyu, Eaves, Richard J., Mayo-Martin, Maria Belen, Laube, Bodo, Jane, David E., Monaghan, Daniel T.
Published in Neuropharmacology (01.03.2012)
Published in Neuropharmacology (01.03.2012)
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Coumarin-3-carboxylic acid derivatives as potentiators and inhibitors of recombinant and native N-methyl-d-aspartate receptors
Irvine, Mark W., Costa, Blaise M., Volianskis, Arturas, Fang, Guangyu, Ceolin, Laura, Collingridge, Graham L., Monaghan, Daniel T., Jane, David E.
Published in Neurochemistry international (01.09.2012)
Published in Neurochemistry international (01.09.2012)
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An interchangeable role for kainate and metabotropic glutamate receptors in the induction of rat hippocampal mossy fiber long-term potentiation in vivo
Wallis, James L., Irvine, Mark W., Jane, David E., Lodge, David, Collingridge, Graham L., Bortolotto, Zuner A.
Published in Hippocampus (01.11.2015)
Published in Hippocampus (01.11.2015)
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N-Methyl-d-aspartate (NMDA) Receptor NR2 Subunit Selectivity of a Series of Novel Piperazine-2,3-dicarboxylate Derivatives: Preferential Blockade of Extrasynaptic NMDA Receptors in the Rat Hippocampal CA3-CA1 Synapse
Costa, Blaise Mathias, Feng, Bihua, Tsintsadze, Timur S, Morley, Richard M, Irvine, Mark W, Tsintsadze, Vera, Lozovaya, Natasha A, Jane, David E, Monaghan, Daniel T
Published in The Journal of pharmacology and experimental therapeutics (01.11.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2009)
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Rhodanine derivatives as novel inhibitors of PDE4
Irvine, Mark W., Patrick, Graham L., Kewney, Justin, Hastings, Stuart F., MacKenzie, Simon J.
Published in Bioorganic & medicinal chemistry (15.03.2008)
Published in Bioorganic & medicinal chemistry (15.03.2008)
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Synthesis of a Series of Novel 3,9-Disubstituted Phenanthrenes as Analogues of Known N-Methyl-d-aspartate Receptor Allosteric Modulators
Irvine, Mark W., Fang, Guangyu, Eaves, Richard, Mayo-Martin, Maria B., Burnell, Erica S., Costa, Blaise M., Culley, Georgia R., Volianskis, Arturas, Collingridge, Graham L., Monaghan, Daniel T., Jane, David E.
Published in Synthesis (Stuttgart) (01.06.2015)
Published in Synthesis (Stuttgart) (01.06.2015)
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