Discovery of CRBN E3 Ligase Modulator CC-92480 for the Treatment of Relapsed and Refractory Multiple Myeloma
Hansen, Joshua D, Correa, Matthew, Nagy, Mark A, Alexander, Matt, Plantevin, Veronique, Grant, Virginia, Whitefield, Brandon, Huang, Dehua, Kercher, Timothy, Harris, Roy, Narla, Rama Krishna, Leisten, Jim, Tang, Yang, Moghaddam, Mehran, Ebinger, Katalin, Piccotti, Joseph, Havens, Courtney G, Cathers, Brian, Carmichael, James, Daniel, Thomas, Vessey, Rupert, Hamann, Lawrence G, Leftheris, Katerina, Mendy, Derek, Baculi, Frans, LeBrun, Laurie A, Khambatta, Gody, Lopez-Girona, Antonia
Published in Journal of medicinal chemistry (09.07.2020)
Published in Journal of medicinal chemistry (09.07.2020)
Get full text
Journal Article
Green chemistry tools to influence a medicinal chemistry and research chemistry based organisation
Alfonsi, Kim, Colberg, Juan, Dunn, Peter J., Fevig, Thomas, Jennings, Sandra, Johnson, Timothy A., Kleine, H. Peter, Knight, Craig, Nagy, Mark A., Perry, David A., Stefaniak, Mark
Published in Green chemistry : an international journal and green chemistry resource : GC (01.01.2008)
Published in Green chemistry : an international journal and green chemistry resource : GC (01.01.2008)
Get full text
Journal Article
Discovery of the c‑Jun N‑Terminal Kinase Inhibitor CC-90001
Nagy, Mark A, Hilgraf, Robert, Mortensen, Deborah S, Elsner, Jan, Norris, Stephen, Tikhe, Jayashree, Yoon, Won, Paisner, David, Delgado, Mercedes, Erdman, Paul, Haelewyn, Jason, Khambatta, Godrej, Xu, Li, Romanow, William J, Condroski, Kevin, Bahmanyar, Sogole, McCarrick, Meg, Benish, Brent, Blease, Kate, LeBrun, Laurie, Moghaddam, Mehran F, Apuy, Julius, Canan, Stacie S, Bennett, Brydon L, Satoh, Yoshitaka
Published in Journal of medicinal chemistry (23.12.2021)
Published in Journal of medicinal chemistry (23.12.2021)
Get full text
Journal Article
SUBSTITUTED 4-AMINOISOINDOLINE-1,3-DIONE COMPOUNDS AND THEIR USE FOR TREATING LYMPHOMA
ANTONIA LOPEZ-GIRONA, MATTHEW D ALEXANDER, MATTHEW D CORREA, VIRGINIA HEATHER SHARRON GRANT, JOSHUA HANSEN, MARK A NAGY, VERONIQUE PLANTEVIN-KRENITSKY, HUANG DEHUA, SORAYA CARRANCIO, TIMOTHY S KERCHER, ROY L HARRIS
Year of Publication 29.05.2024
Get full text
Year of Publication 29.05.2024
Patent
SUBSTITUTED DIAMINOCARBOXAMIDE AND DIAMINOCARBONITRILE PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
JAYASHREE TIKHE, JAN ELSNER, HILGRAF ROBERT, YOON WON HYUNG, DAVID A PAISNER, SATO YOSHITAKA, MERCEDES DELGADO, PAUL ERDMAN, MCCARRICK MEG, SLOSS MARIAN, MEHRAN F MOGHADDAM, LAURIE ANN LEBRUN, MARK A NAGY, BRYDON L BENNETT, STEPHEN NORRIS, WILLIAM J ROMANOW
Year of Publication 19.12.2023
Get full text
Year of Publication 19.12.2023
Patent
Comparison of V Values for Some Nitrogen- and Metal-Centered π-Bridged Mixed-Valence Compounds
Nelsen, Stephen F, Tran, Hieu Q, Nagy, Mark A
Published in Journal of the American Chemical Society (21.01.1998)
Published in Journal of the American Chemical Society (21.01.1998)
Get full text
Journal Article
SUBSTITUTED DIAMINOCARBOXAMIDE AND DIAMINOCARBONITRILE PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
JAYASHREE TIKHE, JAN ELSNER, HILGRAF ROBERT, YOON WON HYUNG, DAVID A PAISNER, SATO YOSHITAKA, MERCEDES DELGADO, PAUL ERDMAN, MCCARRICK MEG, SLOSS MARIAN, MEHRAN F MOGHADDAM, LAURIE ANN LEBRUN, MARK A NAGY, BRYDON L BENNETT, STEPHEN NORRIS, WILLIAM J ROMANOW
Year of Publication 16.09.2021
Get full text
Year of Publication 16.09.2021
Patent
SOLID FORMS OF 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRIMIDINE-5-CARBOXAMIDE, COMPOSITIONS THEREOF AND METHODS OF THEIR USE
HON-WAH MAN, JALE MUSLEHIDDINOGLU, ZOU DAOZHONG, NATHAN ANDREW BOERSEN, JEAN XU, MARIE GEORGES BEAUCHAMPS, ZOU NANFEI, ANTONIO CHRISTIAN FERRETTI, KELVIN HIN-YEONG YONG, HUANG LIANFENG, ROBERT HILGRAF, MARK A NAGY, LI YING, KOTHARE MOHIR ARUL
Year of Publication 12.11.2020
Get full text
Year of Publication 12.11.2020
Patent
SOLID FORM OF 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRIMIDINE-5-CARBOXAMIDE, COMPOSITION THEREOF, AND APPLICATION METHOD THEREFOR
HON-WAH MAN, JALE MUSLEHIDDINOGLU, ZOU DAOZHONG, NATHAN ANDREW BOERSEN, JEAN XU, MARIE GEORGES BEAUCHAMPS, ZOU NANFEI, ANTONIO CHRISTIAN FERRETTI, KELVIN HIN-YEONG YONG, HUANG LIANFENG, ROBERT HILGRAF, MARK A NAGY, LI YING, KOTHARE MOHIR ARUL
Year of Publication 29.08.2019
Get full text
Year of Publication 29.08.2019
Patent
SUBSTITUTED DIAMINOCARBOXAMIDE AND DIAMINOCARBONITRILE PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
JAYASHREE TIKHE, JAN ELSNER, HILGRAF ROBERT, YOON WON HYUNG, DAVID A PAISNER, SATO YOSHITAKA, MERCEDES DELGADO, PAUL ERDMAN, MCCARRICK MEG, SLOSS MARIAN, MEHRAN F MOGHADDAM, LAURIE ANN LEBRUN, MARK A NAGY, BRYDON L BENNETT, STEPHEN NORRIS, WILLIAM J ROMANOW
Year of Publication 11.07.2019
Get full text
Year of Publication 11.07.2019
Patent
SUBSTITUTED DIAMINOCARBOXAMIDE AND DIAMINOCARBONITRILE PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
JAYASHREE TIKHE, JAN ELSNER, HILGRAF ROBERT, YOON WON HYUNG, DAVID A PAISNER, SATO YOSHITAKA, MERCEDES DELGADO, PAUL ERDMAN, MCCARRICK MEG, SLOSS MARIAN, MEHRAN F MOGHADDAM, LAURIE ANN LEBRUN, MARK A NAGY, BRYDON L BENNETT, STEPHEN NORRIS, WILLIAM J ROMANOW
Year of Publication 05.01.2017
Get full text
Year of Publication 05.01.2017
Patent
Examination of the kinetic mechanism of mitogen-activated protein kinase activated protein kinase-2
Schindler, John F, Godbey, Andrew, Hood, William F, Bolten, Suzanne L, Broadus, Richard M, Kasten, Thomas P, Cassely, Aaron J, Hirsch, Jeffery L, Merwood, Michelle A, Nagy, Mark A, Fok, Kam F, Saabye, Matthew J, Morgan, Heidi M, Compton, Robert P, Mourey, Robert J, Wittwer, Arthur J, Monahan, Joseph B
Published in Biochimica et biophysica acta (29.07.2002)
Published in Biochimica et biophysica acta (29.07.2002)
Get full text
Journal Article
Indirect Determination of Self-Exchange Electron Transfer Rate Constants
Nelsen, Stephen F, Ismagilov, Rustem F, Gentile, Kevin E, Nagy, Mark A, Tran, Hieu Q, Qu, Qinling, Halfen, DeWayne T, Odegard, Amy L, Pladziewicz, Jack R
Published in Journal of the American Chemical Society (19.08.1998)
Published in Journal of the American Chemical Society (19.08.1998)
Get full text
Journal Article
Estimation of Self-Exchange Electron Transfer Rate Constants for Organic Compounds from Stopped-Flow Studies
Nelsen, Stephen F, Ramm, Michael T, Ismagilov, Rustem F, Nagy, Mark A, Trieber, Dwight A, Powell, Douglas R, Chen, Xi, Gengler, Jamie J, Qu, Qinling, Brandt, Jennifer L, Pladziewicz, Jack R
Published in Journal of the American Chemical Society (25.06.1997)
Published in Journal of the American Chemical Society (25.06.1997)
Get full text
Journal Article
TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS
Huang, Fei, Horn, Evan J, Hansen, Joshua D, Nagy, Mark A, Alexander, Matthew D
Year of Publication 18.07.2024
Get full text
Year of Publication 18.07.2024
Patent
TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS
Huang, Fei, Horn, Evan J, Hansen, Joshua D, Nagy, Mark A, Alexander, Matthew D
Year of Publication 07.12.2023
Get full text
Year of Publication 07.12.2023
Patent
TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS
ALEXANDER, Matthew D, HANSEN, Joshua D, NAGY, Mark A, HORN, Evan J, HUANG, Fei
Year of Publication 09.11.2023
Get full text
Year of Publication 09.11.2023
Patent
TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS
ALEXANDER, Matthew D, HANSEN, Joshua D, NAGY, Mark A, HORN, Evan J, HUANG, Fei
Year of Publication 09.11.2023
Get full text
Year of Publication 09.11.2023
Patent
TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS
ALEXANDER, Matthew D, HANSEN, Joshua D, NAGY, Mark A, HORN, Evan J, HUANG, Fei
Year of Publication 09.11.2023
Get full text
Year of Publication 09.11.2023
Patent