PepFect14 mediates the delivery of mRNA into human primary keratinocytes and in vivo
Periyasamy, Kapilraj, Maloverjan, Maria, Biswas, Abhijit, Remm, Anu, Pook, Martin, Rebane, Ana, Pooga, Margus
Published in Frontiers in pharmacology (13.07.2023)
Published in Frontiers in pharmacology (13.07.2023)
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Deciphering the internalization mechanism of WRAP:siRNA nanoparticles
Deshayes, Sébastien, Konate, Karidia, Dussot, Marion, Chavey, Bérengère, Vaissière, Anaïs, Van, Thi Nhu Ngoc, Aldrian, Gudrun, Padari, Kärt, Pooga, Margus, Vivès, Eric, Boisguérin, Prisca
Published in Biochimica et biophysica acta. Biomembranes (01.06.2020)
Published in Biochimica et biophysica acta. Biomembranes (01.06.2020)
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Translocation of cell-penetrating peptides across the plasma membrane is controlled by cholesterol and microenvironment created by membranous proteins
Pae, Janely, Säälik, Pille, Liivamägi, Laura, Lubenets, Dmitri, Arukuusk, Piret, Langel, Ülo, Pooga, Margus
Published in Journal of controlled release (28.10.2014)
Published in Journal of controlled release (28.10.2014)
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Journal Article
Internalisation and Biological Activity of Nucleic Acids Delivering Cell-Penetrating Peptide Nanoparticles Is Controlled by the Biomolecular Corona
Lorents, Annely, Maloverjan, Maria, Padari, Kärt, Pooga, Margus
Published in Pharmaceuticals (Basel, Switzerland) (12.07.2021)
Published in Pharmaceuticals (Basel, Switzerland) (12.07.2021)
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Journal Article
Penetration without cells: Membrane translocation of cell-penetrating peptides in the model giant plasma membrane vesicles
Säälik, Pille, Niinep, Aira, Pae, Janely, Hansen, Mats, Lubenets, Dmitri, Langel, Ülo, Pooga, Margus
Published in Journal of controlled release (30.07.2011)
Published in Journal of controlled release (30.07.2011)
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Journal Article
Enhancement of siRNA transfection by the optimization of fatty acid length and histidine content in the CPP
Porosk, Ly, Arukuusk, Piret, Põhako, Kaisa, Kurrikoff, Kaido, Kiisholts, Kristina, Padari, Kärt, Pooga, Margus, Langel, Ülo
Published in Biomaterials science (24.09.2019)
Published in Biomaterials science (24.09.2019)
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Journal Article
Direct translocation as major cellular uptake for CADY self-assembling peptide-based nanoparticles
Rydström, Anna, Deshayes, Sébastien, Konate, Karidia, Crombez, Laurence, Padari, Kärt, Boukhaddaoui, Hassan, Aldrian, Gudrun, Pooga, Margus, Divita, Gilles
Published in PloS one (05.10.2011)
Published in PloS one (05.10.2011)
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Journal Article
Differential Endosomal Pathways for Radically Modified Peptide Vectors
Arukuusk, Piret, Pärnaste, Ly, Margus, Helerin, Eriksson, N. K. Jonas, Vasconcelos, Luis, Padari, Kärt, Pooga, Margus, Langel, Ülo
Published in Bioconjugate chemistry (16.10.2013)
Published in Bioconjugate chemistry (16.10.2013)
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Journal Article
Divalent Metal Ions Boost Effect of Nucleic Acids Delivered by Cell-Penetrating Peptides
Maloverjan, Maria, Padari, Kärt, Abroi, Aare, Rebane, Ana, Pooga, Margus
Published in Cells (Basel, Switzerland) (21.02.2022)
Published in Cells (Basel, Switzerland) (21.02.2022)
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Journal Article
Formulation of Stable and Homogeneous Cell-Penetrating Peptide NF55 Nanoparticles for Efficient Gene Delivery In Vivo
Freimann, Krista, Arukuusk, Piret, Kurrikoff, Kaido, Pärnaste, Ly, Raid, Raivo, Piirsoo, Andres, Pooga, Margus, Langel, Ülo
Published in Molecular therapy. Nucleic acids (02.03.2018)
Published in Molecular therapy. Nucleic acids (02.03.2018)
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Journal Article
The role of endocytosis in the uptake and intracellular trafficking of PepFect14–nucleic acid nanocomplexes via class A scavenger receptors
Juks, Carmen, Padari, Kärt, Margus, Helerin, Kriiska, Asko, Etverk, Indrek, Arukuusk, Piret, Koppel, Kaida, Ezzat, Kariem, Langel, Ülo, Pooga, Margus
Published in Biochimica et biophysica acta (01.12.2015)
Published in Biochimica et biophysica acta (01.12.2015)
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Journal Article
Expression Pattern and Localization Dynamics of Guanine Nucleotide Exchange Factor RIC8 during Mouse Oogenesis
Saare, Merly, Lulla, Sirje, Tõnissoo, Tambet, Meier, Riho, Kask, Keiu, Ruisu, Katrin, Karis, Alar, Salumets, Andres, Pooga, Margus
Published in PloS one (10.06.2015)
Published in PloS one (10.06.2015)
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Journal Article
Choosing an Optimal Solvent Is Crucial for Obtaining Cell-Penetrating Peptide Nanoparticles with Desired Properties and High Activity in Nucleic Acid Delivery
Biswas, Abhijit, Maloverjan, Maria, Padari, Kärt, Abroi, Aare, Rätsep, Margus, Wärmländer, Sebastian K T S, Jarvet, Jüri, Gräslund, Astrid, Kisand, Vambola, Lõhmus, Rünno, Pooga, Margus
Published in Pharmaceutics (2023)
Published in Pharmaceutics (2023)
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Journal Article
Protein Cargo Delivery Properties of Cell-Penetrating Peptides. A Comparative Study
Säälik, Pille, Elmquist, Anna, Hansen, Mats, Padari, Kärt, Saar, Külliki, Viht, Kaido, Langel, Ülo, Pooga, Margus
Published in Bioconjugate chemistry (01.11.2004)
Published in Bioconjugate chemistry (01.11.2004)
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Journal Article
Dual role of the miR‐146 family in rhinovirus‐induced airway inflammation and allergic asthma exacerbation
Laanesoo, Anet, Urgard, Egon, Periyasamy, Kapilraj, Laan, Martti, Bochkov, Yury A., Aab, Alar, Magilnick, Nathaniel, Pooga, Margus, Gern, James E., Johnston, Sebastian L., Coquet, Jonathan M., Boldin, Mark P., Wengel, Jesper, Altraja, Alan, Bochenek, Grazyna, Jakiela, Bogdan, Rebane, Ana
Published in Clinical and translational medicine (01.06.2021)
Published in Clinical and translational medicine (01.06.2021)
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Journal Article
Ablation of RIC8A function in mouse neurons leads to a severe neuromuscular phenotype and postnatal death
Ruisu, Katrin, Kask, Keiu, Meier, Riho, Saare, Merly, Raid, Raivo, Veraksitš, Alar, Karis, Alar, Tõnissoo, Tambet, Pooga, Margus
Published in PloS one (16.08.2013)
Published in PloS one (16.08.2013)
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Journal Article
Nucleotide exchange factor RIC‐8 is indispensable in mammalian early development
Tõnissoo, Tambet, Lulla, Sirje, Meier, Riho, Saare, Merly, Ruisu, Katrin, Pooga, Margus, Karis, Alar
Published in Developmental dynamics (01.12.2010)
Published in Developmental dynamics (01.12.2010)
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