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Efficacy and Safety of a Recombinant Plant-Based Adjuvanted Covid-19 Vaccine
Hager, Karen J., Pérez Marc, Gonzalo, Gobeil, Philipe, Diaz, Ricardo S., Heizer, Gretchen, Llapur, Conrado, Makarkov, Alexander I., Vasconcellos, Eduardo, Pillet, Stéphane, Riera, Fernando, Saxena, Pooja, Geller Wolff, Priscila, Bhutada, Kapil, Wallace, Garry, Aazami, Hessam, Jones, Christine E., Polack, Fernando P., Ferrara, Luciana, Atkins, Judith, Boulay, Iohann, Dhaliwall, Jiwanjeet, Charland, Nathalie, Couture, Manon M.J., Jiang-Wright, Julia, Landry, Nathalie, Lapointe, Sophie, Lorin, Aurélien, Mahmood, Asif, Moulton, Lawrence H., Pahmer, Emmy, Parent, Julie, Séguin, Annie, Tran, Luan, Breuer, Thomas, Ceregido, Maria-Angeles, Koutsoukos, Marguerite, Roman, François, Namba, Junya, D’Aoust, Marc-André, Trepanier, Sonia, Kimura, Yosuke, Ward, Brian J.
Published in The New England journal of medicine (02.06.2022)
Published in The New England journal of medicine (02.06.2022)
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Plant molecular farming in the wake of the closure of Medicago Inc
Benvenuto, Eugenio, Broer, Inge, D’Aoust, Marc-André, Hitzeroth, Inga, Hundleby, Penny, Menassa, Rima, Oksman-Caldentey, Kirsi-Marja, Peyret, Hadrien, Salgueiro, Sancha, Saxena, Pooja, Stander, Jennifer, Warzecha, Heribert, Ma, Julian
Published in Nature biotechnology (01.07.2023)
Published in Nature biotechnology (01.07.2023)
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Human antibody response to N-glycans present on plant-made influenza virus-like particle (VLP) vaccines
Ward, Brian J., Landry, Nathalie, Trépanier, Sonia, Mercier, Geneviève, Dargis, Michèle, Couture, Manon, D’Aoust, Marc-André, Vézina, Louis-P.
Published in Vaccine (21.10.2014)
Published in Vaccine (21.10.2014)
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Safety, immunogenicity, and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in nonhuman primates
Pillet, Stéphane, Arunachalam, Prabhu S., Andreani, Guadalupe, Golden, Nadia, Fontenot, Jane, Aye, Pyone Pyone, Röltgen, Katharina, Lehmicke, Gabrielle, Gobeil, Philipe, Dubé, Charlotte, Trépanier, Sonia, Charland, Nathalie, D’Aoust, Marc-André, Russell-Lodrigue, Kasi, Monjure, Christopher, Blair, Robert V., Boyd, Scott D., Bohm, Rudolf P., Rappaport, Jay, Villinger, François, Landry, Nathalie, Pulendran, Bali, Ward, Brian J.
Published in Cellular & molecular immunology (01.02.2022)
Published in Cellular & molecular immunology (01.02.2022)
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An oligosaccharyltransferase from Leishmania donovani increases the N-glycan occupancy on plant-produced IgG1
Beihammer, Gernot, König-Beihammer, Julia, Kogelmann, Benjamin, Ruocco, Valentina, Grünwald-Gruber, Clemens, D’Aoust, Marc-André, Lavoie, Pierre-Olivier, Saxena, Pooja, Gach, Johannes S., Steinkellner, Herta, Strasser, Richard
Published in Frontiers in plant science (08.08.2023)
Published in Frontiers in plant science (08.08.2023)
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Production of Biopharmaceuticals in Nicotiana benthamiana—Axillary Stem Growth as a Key Determinant of Total Protein Yield
Goulet, Marie-Claire, Gaudreau, Linda, Gagné, Marielle, Maltais, Anne-Marie, Laliberté, Ann-Catherine, Éthier, Gilbert, Bechtold, Nicole, Martel, Michèle, D’Aoust, Marc-André, Gosselin, André, Pepin, Steeve, Michaud, Dominique
Published in Frontiers in plant science (11.06.2019)
Published in Frontiers in plant science (11.06.2019)
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Development and characterization of a plant-derived norovirus-like particle vaccine
Shapiro, Janna R., Andreani, Guadalupe, Dubé, Charlotte, Berubé, Mélanie, Bussière, Diane, Couture, Manon M.-J., Dargis, Michèle, Hendin, Hilary E., Landry, Nathalie, Lavoie, Pierre-Olivier, Pillet, Stéphane, Ward, Brian J., D'Aoust, Marc-André, Trépanier, Sonia
Published in Vaccine (22.09.2023)
Published in Vaccine (22.09.2023)
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Safety and immunogenicity of an AS03-adjuvanted plant-based SARS-CoV-2 vaccine in Adults with and without Comorbidities
Charland, Nathalie, Gobeil, Philipe, Pillet, Stéphane, Boulay, Iohann, Séguin, Annie, Makarkov, Alexander, Heizer, Gretchen, Bhutada, Kapil, Mahmood, Asif, Trépanier, Sonia, Hager, Karen, Jiang-Wright, Julia, Atkins, Judith, Saxena, Pooja, Cheng, Matthew P., Vinh, Donald C., Boutet, Philippe, Roman, François, Van Der Most, Robbert, Ceregido, Maria Angeles, Dionne, Marc, Tellier, Guy, Gauthier, Jean-Sébastien, Essink, Brandon, Libman, Michael, Haffizulla, Jason, Fréchette, André, D’Aoust, Marc-André, Landry, Nathalie, Ward, Brian J.
Published in npj vaccines (09.11.2022)
Published in npj vaccines (09.11.2022)
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Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
Ward, Brian J., Gobeil, Philipe, Séguin, Annie, Atkins, Judith, Boulay, Iohann, Charbonneau, Pierre-Yves, Couture, Manon, D’Aoust, Marc-André, Dhaliwall, Jiwanjeet, Finkle, Carolyn, Hager, Karen, Mahmood, Asif, Makarkov, Alexander, Cheng, Matthew P., Pillet, Stéphane, Schimke, Patricia, St-Martin, Sylvie, Trépanier, Sonia, Landry, Nathalie
Published in Nature medicine (01.06.2021)
Published in Nature medicine (01.06.2021)
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Plant N-glycan profiling of minute amounts of material
Séveno, Martial, Cabrera, Gleysin, Triguero, Ada, Burel, Carole, Leprince, Jérome, Rihouey, Christophe, Vézina, Louis-Philippe, D’Aoust, Marc-André, Rudd, Pauline M., Royle, L., Dwek, Raymond A., Harvey, David J., Lerouge, Patrice, Cremata, José A., Bardor, Muriel
Published in Analytical biochemistry (01.08.2008)
Published in Analytical biochemistry (01.08.2008)
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Multiplexed, targeted gene editing in Nicotiana benthamiana for glyco‐engineering and monoclonal antibody production
Li, Jin, Stoddard, Thomas J, Demorest, Zachary L, Lavoie, Pierre‐Olivier, Luo, Song, Clasen, Benjamin M, Cedrone, Frederic, Ray, Erin E, Coffman, Andrew P, Daulhac, Aurelie, Yabandith, Ann, Retterath, Adam J, Mathis, Luc, Voytas, Daniel F, D'Aoust, Marc‐André, Zhang, Feng
Published in Plant biotechnology journal (01.02.2016)
Published in Plant biotechnology journal (01.02.2016)
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The production of hemagglutinin-based virus-like particles in plants: a rapid, efficient and safe response to pandemic influenza
D'Aoust, Marc-André, Couture, Manon M.-J., Charland, Nathalie, Trépanier, Sonia, Landry, Nathalie, Ors, Frédéric, Vézina, Louis-P.
Published in Plant biotechnology journal (01.06.2010)
Published in Plant biotechnology journal (01.06.2010)
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An industrial-grade Nicotiana benthamiana line for the production of glycoproteins carrying fucose-free galactosylated N-glycans
Kogelmann, Benjamin, Melnik, Stanislav, Keshvari, Tahereh, Bogner, Michaela, Lavoie, Pierre-Olivier, D`Aoust, Marc-Andre, Hermle, Antonia, Lux, Anja, Strasser, Richard, Stöger, Eva, Steinkellner, Herta
Published in New biotechnology (25.03.2025)
Published in New biotechnology (25.03.2025)
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Durability and cross-reactivity of immune responses induced by a plant-based virus-like particle vaccine for COVID-19
Gobeil, Philipe, Pillet, Stéphane, Boulay, Iohann, Charland, Nathalie, Lorin, Aurélien, Cheng, Matthew P., Vinh, Donald C., Boutet, Philippe, Van Der Most, Robbert, Roman, François, Ceregido, Maria Angeles, Landry, Nathalie, D’Aoust, Marc-André, Ward, Brian J.
Published in Nature communications (12.11.2022)
Published in Nature communications (12.11.2022)
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Protection of Recombinant Mammalian Antibodies from Development-Dependent Proteolysis in Leaves of Nicotiana benthamiana
Robert, Stéphanie, Khalf, Moustafa, Goulet, Marie-Claire, D’Aoust, Marc-André, Sainsbury, Frank, Michaud, Dominique
Published in PloS one (23.07.2013)
Published in PloS one (23.07.2013)
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Molecular responses of agroinfiltrated Nicotiana benthamiana leaves expressing suppressor of silencing P19 and influenza virus‐like particles
Hamel, Louis‐Philippe, Tardif, Rachel, Poirier‐Gravel, Francis, Rasoolizadeh, Asieh, Brosseau, Chantal, Giroux, Geneviève, Lucier, Jean‐François, Goulet, Marie‐Claire, Barrada, Adam, Paré, Marie‐Ève, Roussel, Élise, Comeau, Marc‐André, Lavoie, Pierre‐Olivier, Moffett, Peter, Michaud, Dominique, D'Aoust, Marc‐André
Published in Plant biotechnology journal (01.05.2024)
Published in Plant biotechnology journal (01.05.2024)
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Heterologous expression of influenza haemagglutinin leads to early and transient activation of the unfolded protein response in Nicotiana benthamiana
Hamel, Louis‐Philippe, Comeau, Marc‐André, Tardif, Rachel, Poirier‐Gravel, Francis, Paré, Marie‐Ève, Lavoie, Pierre‐Olivier, Goulet, Marie‐Claire, Michaud, Dominique, D'Aoust, Marc‐André
Published in Plant biotechnology journal (01.05.2024)
Published in Plant biotechnology journal (01.05.2024)
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A genome‐edited N. benthamiana line for industrial‐scale production of recombinant glycoproteins with targeted N‐glycosylation
Kogelmann, Benjamin, Melnik, Stanislav, Bogner, Michaela, Kallolimath, Somanath, Stöger, Eva, Sun, Lin, Strasser, Richard, D'Aoust, Marc‐André, Lavoie, Pierre‐Olivier, Saxena, Pooja, Gach, Johannes S., Steinkellner, Herta
Published in Biotechnology journal (01.01.2024)
Published in Biotechnology journal (01.01.2024)
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Expression of a constitutively active nitrate reductase increases SARS‐CoV‐2 Spike protein production in Nicotiana benthamiana leaves that otherwise show traits of senescence
Hamel, Louis‐Philippe, Paré, Marie‐Ève, Poirier‐Gravel, Francis, Tardif, Rachel, Comeau, Marc‐André, Lavoie, Pierre‐Olivier, Langlois, Andréane, Goulet, Marie‐Claire, D'Aoust, Marc‐André, Michaud, Dominique
Published in Plant biotechnology journal (08.06.2025)
Published in Plant biotechnology journal (08.06.2025)
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