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Devalaraja-Narashimha, Kishor, Huang, Cong, Cao, Marc, Chen, Ya Ping, Borodovsky, Anna, Olson, William C, Morton, Lori G, Retter, Marc W
Published in PloS one (16.06.2022)
Published in PloS one (16.06.2022)
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Inhibition of complement pathway activation with Pozelimab, a fully human antibody to complement component C5
Latuszek, Adrianna, Liu, Yashu, Olsen, Olav, Foster, Randi, Cao, Marc, Lovric, Irena, Yuan, Ming, Liu, Nina, Chen, Henry, Zhang, Qian, Xiao, Hui, Springer, Carola, Ehrlich, George, Kamat, Vishal, Rafique, Ashique, Hu, Ying, Krueger, Pamela, Huang, Tammy, Poueymirou, William, Babb, Robert, Rosconi, Michael P, Retter, Marc W, Chen, Gang, Morton, Lori, Zambrowicz, Brian, Cao, Jingtai, Romano, Carmelo, Olson, William C
Published in PloS one (08.05.2020)
Published in PloS one (08.05.2020)
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Translational findings for odronextamab: From preclinical research to a first‐in‐human study in patients with CD20+ B‐cell malignancies
Zhu, Min, Olson, Kara, Kirshner, Jessica R., Khaksar Toroghi, Masood, Yan, Hong, Haber, Lauric, Meagher, Craig, Flink, Dina M., Ambati, Srikanth R., Davis, John D., DiCioccio, A. Thomas, Smith, Eric J., Retter, Marc W.
Published in Clinical and translational science (01.04.2022)
Published in Clinical and translational science (01.04.2022)
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Anti-PCSK9 antibody pharmacokinetics and low-density lipoprotein-cholesterol pharmacodynamics in nonhuman primates are antigen affinity-dependent and exhibit limited sensitivity to neonatal Fc receptor-binding enhancement
Henne, Kirk R, Ason, Brandon, Howard, Monique, Wang, Wei, Sun, Jeonghoon, Higbee, Jared, Tang, Jie, Matsuda, Katherine C, Xu, Ren, Zhou, Lei, Chan, Joyce C Y, King, Chadwick, Piper, Derek E, Ketchem, Randal R, Michaels, Mark Leo, Jackson, Simon M, Retter, Marc W
Published in The Journal of pharmacology and experimental therapeutics (01.04.2015)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2015)
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Effects of AMG 145 on Low-Density Lipoprotein Cholesterol Levels
Dias, Clapton S., PhD, Shaywitz, Adam J., MD, PhD, Wasserman, Scott M., MD, Smith, Brian P., PhD, Gao, Bing, PhD, Stolman, Dina S., MD, MSPH, Crispino, Caroline P., MS, Smirnakis, Karen V., MD, MPH, PhD, Emery, Maurice G., PhD, Colbert, Alexander, BA, Gibbs, John P., PhD, Retter, Marc W., PhD, Cooke, Blaire P., PharmD, Uy, Stephen T., MS, Matson, Mark, MD, Stein, Evan A., MD, PhD
Published in Journal of the American College of Cardiology (06.11.2012)
Published in Journal of the American College of Cardiology (06.11.2012)
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A Mucin 16 bispecific T cell-engaging antibody for the treatment of ovarian cancer
Crawford, Alison, Haber, Lauric, Kelly, Marcus P, Vazzana, Kristin, Canova, Lauren, Ram, Priyanka, Pawashe, Arpita, Finney, Jennifer, Jalal, Sumreen, Chiu, Danica, Colleton, Curtis A, Garnova, Elena, Makonnen, Sosina, Hickey, Carlos, Krueger, Pamela, DelFino, Frank, Potocky, Terra, Kuhnert, Jessica, Godin, Stephen, Retter, Marc W, Duramad, Paurene, MacDonald, Douglas, Olson, William C, Fairhurst, Jeanette, Huang, Tammy, Martin, Joel, Lin, John C, Smith, Eric, Thurston, Gavin, Kirshner, Jessica R
Published in Science translational medicine (19.06.2019)
Published in Science translational medicine (19.06.2019)
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Effects of AMG 145 on Low-Density Lipoprotein Cholesterol Levels: Results From 2 Randomized, Double-Blind, Placebo-Controlled, Ascending-Dose Phase 1 Studies in Healthy Volunteers and Hypercholesterolemic Subjects on Statins
DIAS, Clapton S, SHAYWITZ, Adam J, GIBBS, John P, RETTER, Marc W, COOKE, Blaire P, UY, Stephen T, MATSON, Mark, STEIN, Evan A, WASSERMAN, Scott M, SMITH, Brian P, BING GAO, STOLMAN, Dina S, CRISPINO, Caroline P, SMIRNAKIS, Karen V, EMERY, Maurice G, COLBERT, Alexander
Published in Journal of the American College of Cardiology (06.11.2012)
Published in Journal of the American College of Cardiology (06.11.2012)
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Industry Perspective on First-in-Human and Clinical Pharmacology Strategies to Support Clinical Development of T-Cell Engaging Bispecific Antibodies for Cancer Therapy
Nagaraja Shastri, Prathap, Shah, Nirav, Lechmann, Martin, Mody, Hardik, Retter, Marc W, Zhu, Min, Li, Tommy, Wang, Jun, Shaik, Naveed, Zheng, Xirong, Ovacik, Meric, Hua, Fei, Jawa, Vibha, Boetsch, Christophe, Cao, Yanguang, Burke, John, Datta, Kaushik, Gadkar, Kapil, Upreti, Vijay, Betts, Alison
Published in Clinical pharmacology and therapeutics (19.09.2024)
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A Biparatopic Antibody-Drug Conjugate to Treat MET-Expressing Cancers, Including Those that Are Unresponsive to MET Pathway Blockade
DaSilva, John O, Yang, Katie, Surriga, Oliver, Nittoli, Thomas, Kunz, Arthur, Franklin, Matthew C, Delfino, Frank J, Mao, Shu, Zhao, Feng, Giurleo, Jason T, Kelly, Marcus P, Makonnen, Sosina, Hickey, Carlos, Krueger, Pamela, Foster, Randi, Chen, Zhaoyuan, Retter, Marc W, Slim, Rabih, Young, Tara M, Olson, William C, Thurston, Gavin, Daly, Christopher
Published in Molecular cancer therapeutics (01.10.2021)
Published in Molecular cancer therapeutics (01.10.2021)
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Generation of T-cell-redirecting bispecific antibodies with differentiated profiles of cytokine release and biodistribution by CD3 affinity tuning
Haber, Lauric, Olson, Kara, Kelly, Marcus P., Crawford, Alison, DiLillo, David J., Tavaré, Richard, Ullman, Erica, Mao, Shu, Canova, Lauren, Sineshchekova, Olga, Finney, Jennifer, Pawashe, Arpita, Patel, Supriya, McKay, Ryan, Rizvi, Sahar, Damko, Ermelinda, Chiu, Danica, Vazzana, Kristin, Ram, Priyanka, Mohrs, Katja, D’Orvilliers, Amanda, Xiao, Jenny, Makonnen, Sosina, Hickey, Carlos, Arnold, Cody, Giurleo, Jason, Chen, Ya Ping, Thwaites, Courtney, Dudgeon, Drew, Bray, Kevin, Rafique, Ashique, Huang, Tammy, Delfino, Frank, Hermann, Aynur, Kirshner, Jessica R., Retter, Marc W., Babb, Robert, MacDonald, Douglas, Chen, Gang, Olson, William C., Thurston, Gavin, Davis, Samuel, Lin, John C., Smith, Eric
Published in Scientific reports (13.07.2021)
Published in Scientific reports (13.07.2021)
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proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates
Chan, Joyce C.Y, Piper, Derek E, Cao, Qiong, Liu, Dongming, King, Chadwick, Wang, Wei, Tang, Jie, Liu, Qiang, Higbee, Jared, Xia, Zhen, Di, Yongmei, Shetterly, Susan, Arimura, Ziva, Salomonis, Heather, Romanow, William G, Thibault, Stephen T, Zhang, Richard, Cao, Ping, Yang, Xiao-Ping, Yu, Timothy, Lu, Mei, Retter, Marc W, Kwon, Gayle, Henne, Kirk, Pan, Oscar, Tsai, Mei-Mei, Fuchslocher, Bryna, Yang, Evelyn, Zhou, Lei, Lee, Ki Jeong, Daris, Mark, Sheng, Jackie, Wang, Yan, Shen, Wenyan D, Yeh, Wen-Chen, Emery, Maurice, Walker, Nigel P.C, Shan, Bei, Schwarz, Margrit, Jackson, Simon M
Published in Proceedings of the National Academy of Sciences - PNAS (16.06.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (16.06.2009)
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A BCMAxCD3 bispecific T cell–engaging antibody demonstrates robust antitumor efficacy similar to that of anti-BCMA CAR T cells
DiLillo, David J., Olson, Kara, Mohrs, Katja, Meagher, Thomas Craig, Bray, Kevin, Sineshchekova, Olga, Startz, Thomas, Kuhnert, Jessica, Retter, Marc W., Godin, Stephen, Sharma, Prachi, Delfino, Frank, Lin, John, Smith, Eric, Thurston, Gavin, Kirshner, Jessica R.
Published in Blood advances (09.03.2021)
Published in Blood advances (09.03.2021)
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Preclinical PET imaging with the novel human antibody 89 Zr-DFO-REGN3504 sensitively detects PD-L1 expression in tumors and normal tissues
Kelly, Marcus P, Makonnen, Sosina, Hickey, Carlos, Arnold, T Cody, Giurleo, Jason T, Tavaré, Richard, Danton, Makenzie, Granados, Christian, Chatterjee, Ishita, Dudgeon, Drew, Retter, Marc W, Ma, Dangshe, Olson, William C, Thurston, Gavin, Kirshner, Jessica R
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Published in Journal for immunotherapy of cancer (01.01.2021)
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Impact of Glycation on Antibody Clearance
Yang, Jane, Primack, Ronya, Frohn, Mike, Wang, Wei, Luan, Peng, Retter, Marc W., Flynn, Gregory C.
Published in The AAPS journal (01.01.2015)
Published in The AAPS journal (01.01.2015)
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Placental Transfer of a Fully Human IgG2 Monoclonal Antibody in the Cynomolgus Monkey, Rat, and Rabbit: A Comparative Assessment from during Organogenesis to Late Gestation
Moffat, Graeme J., Retter, Marc W., Kwon, Gayle, Loomis, Mark, Hock, M. Benjamin, Hall, Colin, Bussiere, Jeanine, Lewis, Elise M., Chellman, Gary J.
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.04.2014)
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.04.2014)
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Investigation of maternal and fetal exposure to an IgG2 monoclonal antibody following biweekly intravaginal administration to cynomolgus monkeys throughout pregnancy
Moffat, Graeme J., Davies, Rhian, Kwon, Gayle, Retter, Marc W., Chellman, Gary J., Kanapuram, Sekhar, Moore, Meghan, Loomis, Mark, Wang, Wei, Pyrah, Ian T.G.
Published in Reproductive toxicology (Elmsford, N.Y.) (01.09.2014)
Published in Reproductive toxicology (Elmsford, N.Y.) (01.09.2014)
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Serum Antibodies to Lipophilin B Detected in Late Stage Breast Cancer Patients
CARTER, Darrick, DILLON, Davin C, PERSING, David H, HOUGHTON, Raymond L, REYNOLDS, Lisa D, RETTER, Marc W, FANGER, Gary, MOLESH, David A, SLEATH, Paul R, MCNEILL, Patricia D, VEDVICK, Thomas S, REED, Steven G
Published in Clinical cancer research (01.02.2003)
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Published in Clinical cancer research (01.02.2003)
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Preclinical PET imaging with the novel human antibody 89Zr-DFO-REGN3504 sensitively detects PD-L1 expression in tumors and normal tissues
Kelly, Marcus P, Makonnen, Sosina, Hickey, Carlos, Arnold, T Cody, Giurleo, Jason T, Tavaré, Richard, Danton, Makenzie, Granados, Christian, Chatterjee, Ishita, Dudgeon, Drew, Retter, Marc W, Ma, Dangshe, Olson, William C, Thurston, Gavin, Kirshner, Jessica R
Published in Journal for immunotherapy of cancer (01.01.2021)
Published in Journal for immunotherapy of cancer (01.01.2021)
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