The T cell receptor repertoire of tumor infiltrating T cells is predictive and prognostic for cancer survival
Valpione, Sara, Mundra, Piyushkumar A., Galvani, Elena, Campana, Luca G., Lorigan, Paul, De Rosa, Francesco, Gupta, Avinash, Weightman, John, Mills, Sarah, Dhomen, Nathalie, Marais, Richard
Published in Nature communications (02.07.2021)
Published in Nature communications (02.07.2021)
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Journal Article
Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF
Heidorn, Sonja J., Milagre, Carla, Whittaker, Steven, Nourry, Arnaud, Niculescu-Duvas, Ion, Dhomen, Nathalie, Hussain, Jahan, Reis-Filho, Jorge S., Springer, Caroline J., Pritchard, Catrin, Marais, Richard
Published in Cell (22.01.2010)
Published in Cell (22.01.2010)
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Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy
Smith, Michael P., Brunton, Holly, Rowling, Emily J., Ferguson, Jennifer, Arozarena, Imanol, Miskolczi, Zsofia, Lee, Jessica L., Girotti, Maria R., Marais, Richard, Levesque, Mitchell P., Dummer, Reinhard, Frederick, Dennie T., Flaherty, Keith T., Cooper, Zachary A., Wargo, Jennifer A., Wellbrock, Claudia
Published in Cancer cell (14.03.2016)
Published in Cancer cell (14.03.2016)
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Journal Article
Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF
Wellbrock, Claudia, Rana, Sareena, Paterson, Hugh, Pickersgill, Helen, Brummelkamp, Thijn, Marais, Richard
Published in PloS one (16.07.2008)
Published in PloS one (16.07.2008)
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Journal Article
Application of Sequencing, Liquid Biopsies, and Patient-Derived Xenografts for Personalized Medicine in Melanoma
Girotti, Maria Romina, Gremel, Gabriela, Lee, Rebecca, Galvani, Elena, Rothwell, Dominic, Viros, Amaya, Mandal, Amit Kumar, Lim, Kok Haw Jonathan, Saturno, Grazia, Furney, Simon J, Baenke, Franziska, Pedersen, Malin, Rogan, Jane, Swan, Jacqueline, Smith, Matthew, Fusi, Alberto, Oudit, Deemesh, Dhomen, Nathalie, Brady, Ged, Lorigan, Paul, Dive, Caroline, Marais, Richard
Published in Cancer discovery (01.03.2016)
Published in Cancer discovery (01.03.2016)
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Journal Article
Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma
Girotti, Maria R, Pedersen, Malin, Sanchez-Laorden, Berta, Viros, Amaya, Turajlic, Samra, Niculescu-Duvaz, Dan, Zambon, Alfonso, Sinclair, John, Hayes, Andrew, Gore, Martin, Lorigan, Paul, Springer, Caroline, Larkin, James, Jorgensen, Claus, Marais, Richard
Published in Cancer discovery (01.02.2013)
Published in Cancer discovery (01.02.2013)
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Journal Article
BRAF signaling and targeted therapies in melanoma
Dhomen, Nathalie, Marais, Richard
Published in Hematology/oncology clinics of North America (01.06.2009)
Published in Hematology/oncology clinics of North America (01.06.2009)
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Journal Article
ROCK and JAK1 Signaling Cooperate to Control Actomyosin Contractility in Tumor Cells and Stroma
Sanz-Moreno, Victoria, Gaggioli, Cedric, Yeo, Maggie, Albrengues, Jean, Wallberg, Fredrik, Viros, Amaya, Hooper, Steven, Mitter, Richard, Féral, Chloé C., Cook, Martin, Larkin, James, Marais, Richard, Meneguzzi, Guerrino, Sahai, Erik, Marshall, Chris J.
Published in Cancer cell (16.08.2011)
Published in Cancer cell (16.08.2011)
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Journal Article
Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface
Tang, HaoRan, Leung, Leo, Saturno, Grazia, Viros, Amaya, Smith, Duncan, Di Leva, Gianpiero, Morrison, Eamonn, Niculescu-Duvaz, Dan, Lopes, Filipa, Johnson, Louise, Dhomen, Nathalie, Springer, Caroline, Marais, Richard
Published in Nature communications (18.04.2017)
Published in Nature communications (18.04.2017)
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Journal Article
Resistance to BRAF inhibitors induces glutamine dependency in melanoma cells
Baenke, Franziska, Chaneton, Barbara, Smith, Matthew, Van Den Broek, Niels, Hogan, Kate, Tang, Haoran, Viros, Amaya, Martin, Matthew, Galbraith, Laura, Girotti, Maria R., Dhomen, Nathalie, Gottlieb, Eyal, Marais, Richard
Published in Molecular oncology (01.01.2016)
Published in Molecular oncology (01.01.2016)
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Journal Article
Intravital Imaging Reveals Transient Changes in Pigment Production and Brn2 Expression during Metastatic Melanoma Dissemination
PINNER, Sophie, JORDAN, Peter, SHARROCK, Kirsty, BAZLEY, Laura, COLLINSON, Lucy, MARAIS, Richard, BONVIN, Elise, GODING, Colin, SAHAI, Erik
Published in Cancer research (Chicago, Ill.) (15.10.2009)
Published in Cancer research (Chicago, Ill.) (15.10.2009)
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Journal Article
Ultraviolet radiation drives mutations in a subset of mucosal melanomas
Mundra, Piyushkumar A., Dhomen, Nathalie, Rodrigues, Manuel, Mikkelsen, Lauge Hjorth, Cassoux, Nathalie, Brooks, Kelly, Valpione, Sara, Reis-Filho, Jorge S., Heegaard, Steffen, Stern, Marc-Henri, Roman-Roman, Sergio, Marais, Richard
Published in Nature communications (11.01.2021)
Published in Nature communications (11.01.2021)
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Journal Article
Elucidating distinct roles for NF1 in melanomagenesis
Maertens, Ophélia, Johnson, Bryan, Hollstein, Pablo, Frederick, Dennie T, Cooper, Zachary A, Messiaen, Ludwine, Bronson, Roderick T, McMahon, Martin, Granter, Scott, Flaherty, Keith, Wargo, Jennifer A, Marais, Richard, Cichowski, Karen
Published in Cancer discovery (01.03.2013)
Published in Cancer discovery (01.03.2013)
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Journal Article
Anti-metastatic Inhibitors of Lysyl Oxidase (LOX): Design and Structure–Activity Relationships
Leung, Leo, Niculescu-Duvaz, Dan, Smithen, Deborah, Lopes, Filipa, Callens, Cedric, McLeary, Robert, Saturno, Grazia, Davies, Lawrence, Aljarah, Mohammed, Brown, Michael, Johnson, Louise, Zambon, Alfonso, Chambers, Tim, Ménard, Delphine, Bayliss, Natasha, Knight, Ruth, Fish, Laura, Lawrence, Rae, Challinor, Mairi, Tang, HaoRan, Marais, Richard, Springer, Caroline
Published in Journal of medicinal chemistry (27.06.2019)
Published in Journal of medicinal chemistry (27.06.2019)
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Journal Article
Wild-Type and Mutant B-RAF Activate C-RAF through Distinct Mechanisms Involving Heterodimerization
Garnett, Mathew J., Rana, Sareena, Paterson, Hugh, Barford, David, Marais, Richard
Published in Molecular cell (22.12.2005)
Published in Molecular cell (22.12.2005)
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Journal Article
Analysis of the efficacy and toxicity of sorafenib in thyroid cancer: a phase II study in a UK based population
Ahmed, Merina, Barbachano, Yolanda, Riddell, Angela, Hickey, Jen, Newbold, Katie L, Viros, Amaya, Harrington, Kevin J, Marais, Richard, Nutting, Christopher M
Published in European journal of endocrinology (01.08.2011)
Published in European journal of endocrinology (01.08.2011)
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Journal Article
The mutational burden of acral melanoma revealed by whole-genome sequencing and comparative analysis
Furney, Simon J., Turajlic, Samra, Stamp, Gordon, Thomas, J. Meirion, Hayes, Andrew, Strauss, Dirk, Gavrielides, Mike, Xing, Wei, Gore, Martin, Larkin, James, Marais, Richard
Published in Pigment cell and melanoma research (01.09.2014)
Published in Pigment cell and melanoma research (01.09.2014)
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