Loading…
PM2.5 promotes platelet activation and thrombosis via ROS/MAPKs pathway-mediated mitochondrial dysfunction
Xie, Yuquan, Fan, Dongxia, Wu, Biao, Guo, Jianshu, Wang, Ge, Yu, Lu, Zhang, Chihang, Zhao, Jinzhuo, Zhang, Si
Published in Environmental research (15.10.2025)
Published in Environmental research (15.10.2025)
Get full text
Journal Article
Loading…
PM 2.5 promotes platelet activation and thrombosis via ROS/MAPKs pathway-mediated mitochondrial dysfunction
Xie, Yuquan, Fan, Dongxia, Wu, Biao, Guo, Jianshu, Wang, Ge, Yu, Lu, Zhang, Chihang, Zhao, Jinzhuo, Zhang, Si
Published in Environmental research (09.06.2025)
Published in Environmental research (09.06.2025)
Get full text
Journal Article
Loading…
Neuroprotective Effect of Oxysophocarpine by Modulation of MAPK Pathway in Rat Hippocampal Neurons Subject to Oxygen–Glucose Deprivation and Reperfusion
Zhao, Peng, Chang, Ren-Yuan, Liu, Ning, Wang, Jing, Zhou, Ru, Qi, Xue, Liu, Yue, Ma, Lin, Niu, Yang, Sun, Tao, Li, Yu-Xiang, He, Yan-Ping, Yu, Jian-Qiang
Published in Cellular and molecular neurobiology (01.03.2018)
Published in Cellular and molecular neurobiology (01.03.2018)
Get full text
Journal Article
Loading…
Propranolol Suppresses the Growth of Colorectal Cancer Through Simultaneously Activating Autologous CD8 + T Cells and Inhibiting Tumor AKT/MAPK Pathway
Liao, Ping, Song, Kun, Zhu, Zhanwei, Liu, Zhaoqian, Zhang, Wei, Li, Wei, Hu, Jiali, Hu, Qian, Chen, Cuiyu, Chen, Bohua, McLeod, Howard L, Pei, Haiping, Chen, Ling, He, Yijing
Published in Clinical pharmacology and therapeutics (01.09.2020)
Published in Clinical pharmacology and therapeutics (01.09.2020)
Get more information
Journal Article
Loading…
678TiP A phase I, first-in-human, dose escalation and expansion study of oral pan-RAF/MEK molecular glue NST-628 in subjects with solid tumors harboring RAS-MAPK pathway alterations
Lemech, C., Luke, J.J., Falchook, G.S., Mckean, M., Kichenadasse, G., Teng, C., Vandross, A.L., Salkeni, M.A., Atkinson, V.G., Liu, J.J., Kennedy, A.M., Clark, J., Ryan, M., Schmidt-Kittler, O., Steinhubel, D., Wages, D., Komarnitsky, P., Puzanov, I.
Published in Annals of oncology (01.09.2024)
Published in Annals of oncology (01.09.2024)
Get full text
Journal Article
Loading…
MAPK Pathway Inhibitors in Thyroid Cancer: Preclinical and Clinical Data
Schubert, Louis, Mariko, Mohamed Lamine, Clerc, Jérôme, Huillard, Olivier, Groussin, Lionel
Published in Cancers (24.01.2023)
Published in Cancers (24.01.2023)
Get full text
Journal Article
Loading…
Multiomic ALS signatures highlight subclusters and sex differences suggesting the MAPK pathway as therapeutic target
Caldi Gomes, Lucas, Hänzelmann, Sonja, Hausmann, Fabian, Khatri, Robin, Oller, Sergio, Parvaz, Mojan, Tzeplaeff, Laura, Pasetto, Laura, Gebelin, Marie, Ebbing, Melanie, Holzapfel, Constantin, Columbro, Stefano Fabrizio, Scozzari, Serena, Knöferle, Johanna, Cordts, Isabell, Demleitner, Antonia F., Deschauer, Marcus, Dufke, Claudia, Sturm, Marc, Zhou, Qihui, Zelina, Pavol, Sudria-Lopez, Emma, Haack, Tobias B., Streb, Sebastian, Kuzma-Kozakiewicz, Magdalena, Edbauer, Dieter, Pasterkamp, R. Jeroen, Laczko, Endre, Rehrauer, Hubert, Schlapbach, Ralph, Carapito, Christine, Bonetto, Valentina, Bonn, Stefan, Lingor, Paul
Published in Nature communications (07.06.2024)
Published in Nature communications (07.06.2024)
Get full text
Journal Article
Loading…
The role of MAPK pathway in gastric cancer: unveiling molecular crosstalk and therapeutic prospects
Yuan, Weiwei, Shi, Yin, Dai, Shiping, Deng, Mao, Zhu, Kai, Xu, Yuanmin, Chen, Zhangming, Xu, Zhou, Zhang, Tianlong, Liang, Song
Published in Journal of translational medicine (24.12.2024)
Published in Journal of translational medicine (24.12.2024)
Get full text
Journal Article
Loading…
Gut Microbiota and Therapy in Metastatic Melanoma: Focus on MAPK Pathway Inhibition
Guardamagna, Mora, Berciano-Guerrero, Miguel-Angel, Villaescusa-González, Beatriz, Perez-Ruiz, Elisabeth, Oliver, Javier, Lavado-Valenzuela, Rocío, Rueda-Dominguez, Antonio, Barragán, Isabel, Queipo-Ortuño, María Isabel
Published in International journal of molecular sciences (09.10.2022)
Published in International journal of molecular sciences (09.10.2022)
Get full text
Journal Article
Loading…
Butyrate promotes C2C12 myoblast proliferation by activating ERK/MAPK pathway
Guan, Li, Cao, Ziyi, Pan, Ziyue, Zhao, Chao, Xue, Mengjuan, Yang, Fan, Chen, Jie
Published in Molecular omics (14.08.2023)
Published in Molecular omics (14.08.2023)
Get full text
Journal Article
Loading…
Loading…
AD-1, a novel ginsenoside derivative, shows anti-lung cancer activity via activation of p38 MAPK pathway and generation of reactive oxygen species
Zhang, Lin-Hui, Jia, Yong-Liang, Lin, Xi-Xi, Zhang, Hong-Quan, Dong, Xin-Wei, Zhao, Jun-Ming, Shen, Jian, Shen, Hui-Juan, Li, Fen-fen, Yan, Xiao-Feng, Li, Wei, Zhao, Yu-Qing, Xie, Qiang-Min
Published in Biochimica et biophysica acta (01.08.2013)
Published in Biochimica et biophysica acta (01.08.2013)
Get full text
Journal Article
Loading…
Selenomethionine Alleviates Deoxynivalenol-Induced Oxidative Injury in Porcine Intestinal Epithelial Cells Independent of MAPK Pathway Regulation
Huang, Zhouyin, Zhong, Haopeng, Li, Ting, Wang, Zirui, Chen, Xingping, Zou, Tiande, You, Jinming, Chen, Jun
Published in Antioxidants (16.03.2024)
Published in Antioxidants (16.03.2024)
Get full text
Journal Article
Loading…
Loading…
Cathepsin C Is Involved in Macrophage M1 Polarization via p38/MAPK Pathway in Sudden Cardiac Death
Dai, Jialin, Liu, Jiangjin, Zhang, Qiong, An, Yang, Xia, Bing, Wan, Changwu, Zhang, Yuanyuan, Yu, Yanni, Wang, Jie
Published in Cardiovascular therapeutics (15.10.2021)
Published in Cardiovascular therapeutics (15.10.2021)
Get full text
Journal Article
Loading…
Aristolochic Acid Affects Upper Tract Urothelial Cancer Behavior through the MAPK Pathway
Chen, I-Hsuan, Luo, Hao-Lun, Su, Yu-Li, Huang, Chun-Chieh, Chiang, Po-Hui, Yu, Chia-Cheng, Lee, Nai-Lun, Lin, Jen-Jie, Sung, Ming-Tse
Published in Molecules (Basel, Switzerland) (15.10.2019)
Published in Molecules (Basel, Switzerland) (15.10.2019)
Get full text
Journal Article
Loading…
Loading…
Concurrent MEK targeted therapy prevents MAPK pathway reactivation during BRAFV600E targeted inhibition in a novel syngeneic murine glioma model
Grossauer, Stefan, Koeck, Katharina, Murphy, Nicole E., Meyers, Ian D., Daynac, Mathieu, Truffaux, Nathalene, Truong, Albert Y., Nicolaides, Theodore P., McMahon, Martin, Berger, Mitchel S., Phillips, Joanna J., James, C. David, Petritsch, Claudia K.
Published in Oncotarget (15.11.2016)
Published in Oncotarget (15.11.2016)
Get full text
Journal Article