Lead identification of novel and selective TYK2 inhibitors
Liang, Jun, Tsui, Vickie, Van Abbema, Anne, Bao, Liang, Barrett, Kathy, Beresini, Maureen, Berezhkovskiy, Leo, Blair, Wade S., Chang, Christine, Driscoll, James, Eigenbrot, Charles, Ghilardi, Nico, Gibbons, Paul, Halladay, Jason, Johnson, Adam, Kohli, Pawan Bir, Lai, Yingjie, Liimatta, Marya, Mantik, Priscilla, Menghrajani, Kapil, Murray, Jeremy, Sambrone, Amy, Xiao, Yisong, Shia, Steven, Shin, Young, Smith, Jan, Sohn, Sue, Stanley, Mark, Ultsch, Mark, Zhang, Birong, Wu, Lawren C., Magnuson, Steven
Published in European journal of medicinal chemistry (01.09.2013)
Published in European journal of medicinal chemistry (01.09.2013)
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Journal Article
Lead Optimization of a 4‑Aminopyridine Benzamide Scaffold To Identify Potent, Selective, and Orally Bioavailable TYK2 Inhibitors
Liang, Jun, van Abbema, Anne, Balazs, Mercedesz, Barrett, Kathy, Berezhkovsky, Leo, Blair, Wade, Chang, Christine, Delarosa, Donnie, DeVoss, Jason, Driscoll, Jim, Eigenbrot, Charles, Ghilardi, Nico, Gibbons, Paul, Halladay, Jason, Johnson, Adam, Kohli, Pawan Bir, Lai, Yingjie, Liu, Yanzhou, Lyssikatos, Joseph, Mantik, Priscilla, Menghrajani, Kapil, Murray, Jeremy, Peng, Ivan, Sambrone, Amy, Shia, Steven, Shin, Young, Smith, Jan, Sohn, Sue, Tsui, Vickie, Ultsch, Mark, Wu, Lawren C, Xiao, Yisong, Yang, Wenqian, Young, Judy, Zhang, Birong, Zhu, Bing-yan, Magnuson, Steven
Published in Journal of medicinal chemistry (13.06.2013)
Published in Journal of medicinal chemistry (13.06.2013)
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Journal Article
Predicting Long-Term Stability of an Oral Delivered Antibody Drug Product with Accelerated Stability Assessment Program Modeling
Dai, Lulu, Davis, Jeff, Nagapudi, Karthik, Mantik, Priscilla, Zhang, Kelly, Pellett, Jackson D., Wei, Bingchuan
Published in Molecular pharmaceutics (01.01.2024)
Published in Molecular pharmaceutics (01.01.2024)
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Journal Article
Probing the Protein–Excipient Interaction in the Orally Delivered Protein by Solid-State Hydrogen–Deuterium Exchange Mass Spectrometry and Molecular Dynamics
Pan, Xiao, Lenka, Sunidhi, Davis, Jeff, Nagapudi, Karthik, Mantik, Priscilla, Saggu, Miguel, Dai, Lulu, Cadang, Lance, Zhang, Hui-Min, Zhang, Jennifer, Izadi, Saeed, Yang, Feng, Wei, Bingchuan
Published in Analytical chemistry (Washington) (16.01.2024)
Published in Analytical chemistry (Washington) (16.01.2024)
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Journal Article
Cyclodextrin Reduces Intravenous Toxicity of a Model Compound
Mantik, Priscilla, Xie, Minli, Wong, Harvey, La, Hank, Steigerwalt, Ronald W., Devanaboyina, Uday, Ganem, Geoffrey, Shih, Danny, Flygare, John A., Fairbrother, Wayne J., Chakravarty, Paroma, Russell, David, Fernandez, Gilberto E., Narang, Ajit S.
Published in Journal of pharmaceutical sciences (01.06.2019)
Published in Journal of pharmaceutical sciences (01.06.2019)
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Journal Article
Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model
Liang, Jun, Van Abbema, Anne, Balazs, Mercedesz, Barrett, Kathy, Berezhkovsky, Leo, Blair, Wade S., Chang, Christine, Delarosa, Donnie, DeVoss, Jason, Driscoll, Jim, Eigenbrot, Charles, Goodacre, Simon, Ghilardi, Nico, MacLeod, Calum, Johnson, Adam, Bir Kohli, Pawan, Lai, Yingjie, Lin, Zhonghua, Mantik, Priscilla, Menghrajani, Kapil, Nguyen, Hieu, Peng, Ivan, Sambrone, Amy, Shia, Steven, Smith, Jan, Sohn, Sue, Tsui, Vickie, Ultsch, Mark, Williams, Karen, Wu, Lawren C., Yang, Wenqian, Zhang, Birong, Magnuson, Steven
Published in Bioorganic & medicinal chemistry letters (15.09.2017)
Published in Bioorganic & medicinal chemistry letters (15.09.2017)
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Journal Article
IMMEDIATE-RELEASE TABLETS CONTAINING A DRUG AND PROCESSES FOR FORMING THE TABLETS
MANTIK, PRISCILLA, MAUERER, ALEXANDER, KOTHARI, SANJEEV, REZAEI, HAMID
Year of Publication 13.05.2024
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Year of Publication 13.05.2024
Patent
IMMEDIATE-RELEASE TABLETS CONTAINING A DRUG AND PROCESSES FOR FORMING THE TABLETS
Rezaei, Hamid, Mauerer, Alexander, Kothari, Sanjeev, Mantik, Priscilla
Year of Publication 29.03.2024
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Year of Publication 29.03.2024
Patent
IMMEDIATE-RELEASE TABLETS CONTAINING A DRUG AND PROCESSES FOR FORMING THE TABLETS
MANTIK, Priscilla, KOTHARI, Sanjeev, MAUERER, Alexander, REZAEI, Hamid
Year of Publication 01.11.2023
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Year of Publication 01.11.2023
Patent
IMMEDIATE-RELEASE TABLETS CONTAINING A DRUG AND PROCESSES FOR FORMING THE TABLETS
MANTIK, PRISCILLA, MAUERER, ALEXANDER, KOTHARI, SANJEEV, REZAEI, HAMID
Year of Publication 24.01.2023
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Year of Publication 24.01.2023
Patent
IMMEDIATE-RELEASE TABLETS CONTAINING A DRUG AND PROCESSES FOR FORMING THE TABLETS
MANTIK, Priscilla, KOTHARI, Sanjeev, MAUERER, Alexander, REZAEI, Hamid
Year of Publication 27.10.2022
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Year of Publication 27.10.2022
Patent
Immediate-release tablets containing a drug and processes for forming the tablets
MANTIK, Priscilla, KOTHARI, Sanjeev, MAUERER, Alexander, REZAEI, Hamid
Year of Publication 10.03.2022
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Year of Publication 10.03.2022
Patent
Immediate-release tablets containing a drug and processes for forming the tablets
Rezaei, Hamid, Mauerer, Alexander, Kothari, Sanjeev, Mantik, Priscilla
Year of Publication 18.11.2021
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Year of Publication 18.11.2021
Patent
IMMEDIATE-RELEASE TABLETS CONTAINING A DRUG AND PROCESSES FOR FORMING THE TABLETS
MANTIK, PRISCILLA, MAUERER, ALEXANDER, KOTHARI, SANJEEV, REZAEI, HAMID
Year of Publication 11.10.2021
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Year of Publication 11.10.2021
Patent
IMMEDIATE-RELEASE TABLETS CONTAINING A DRUG AND PROCESSES FOR FORMING THE TABLETS
MANTIK, Priscilla, KOTHARI, Sanjeev, MAUERER, Alexander, REZAEI, Hamid
Year of Publication 22.09.2021
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Year of Publication 22.09.2021
Patent
IMMEDIATE-RELEASE TABLETS CONTAINING A DRUG AND PROCESSES FOR FORMING THE TABLETS
Rezaei, Hamid, Mauerer, Alexander, Kothari, Sanjeev, Mantik, Priscilla
Year of Publication 09.07.2021
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Year of Publication 09.07.2021
Patent
IMMEDIATE-RELEASE TABLETS CONTAINING A DRUG AND PROCESSES FOR FORMING THE TABLETS
MANTIK, Priscilla, KOTHARI, Sanjeev, MAUERER, Alexander, REZAEI, Hamid
Year of Publication 10.03.2021
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Year of Publication 10.03.2021
Patent