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Published in Journal of medicinal chemistry (11.09.2008)
Published in Journal of medicinal chemistry (11.09.2008)
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Discovery of orally active pyrrolopyridine- and aminopyridine-based Met kinase inhibitors
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Published in Bioorganic & medicinal chemistry (01.06.2008)
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Contribution of Ras GTPase/MAP Kinase and Cytochrome P450 Metabolites to Deoxycorticosterone-Salt–Induced Hypertension
Muthalif, Mubarack M, Benter, Ibrahim F, Khandekar, Zinat, Gaber, Lillian, Estes, Anne, Malik, Suzanna, Parmentier, Jean-Hugues, Manne, Veeraswamy, Malik, Kafait U
Published in Hypertension (Dallas, Tex. 1979) (01.01.2000)
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Phase I Pharmacokinetic and Pharmacodynamic Study of Weekly 1-Hour and 24-Hour Infusion BMS-214662, a Farnesyltransferase Inhibitor, in Patients With Advanced Solid Tumors
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Potent, Cell Active, Non-Thiol Tetrapeptide Inhibitors of Farnesyltransferase
Hunt, John T, Lee, Ving G, Leftheris, Katerina, Seizinger, Bernd, Carboni, Joan, Mabus, John, Ricca, Carol, Yan, Ning, Manne, Veeraswamy
Published in Journal of medicinal chemistry (19.01.1996)
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Farnesyl Diphosphate-Based Inhibitors of Ras Farnesyl Protein Transferase
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Published in Journal of medicinal chemistry (01.07.1995)
Published in Journal of medicinal chemistry (01.07.1995)
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Identification and Preliminary Characterization of Protein-Cysteine Farnesyltransferase
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Published in Proceedings of the National Academy of Sciences - PNAS (01.10.1990)
Published in Proceedings of the National Academy of Sciences - PNAS (01.10.1990)
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Development of Highly Potent Inhibitors of Ras Farnesyltransferase Possessing Cellular and in Vivo Activity
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Published in Journal of medicinal chemistry (05.01.1996)
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A phase Ib study of troriluzole (BHV-4157) in combination with nivolumab
Silk, Ann W., Saraiya, Biren, Groisberg, Roman, Chan, Nancy, Spencer, Kristen Renee, Girda, Eugenia, Shih, Weichung, Manne, Veeraswamy, Palmeri, Marisa, Berman, Robert, Coric, Vlad, Vieth, Joshua, Chen, Suzie, Mehnert, Janice M., Malhotra, Jyoti
Published in Journal of clinical oncology (10.02.2020)
Published in Journal of clinical oncology (10.02.2020)
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Discovery of N-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a Selective and Orally Efficacious Inhibitor of the Met Kinase Superfamily
Schroeder, Gretchen M, An, Yongmi, Cai, Zhen-Wei, Chen, Xiao-Tao, Clark, Cheryl, Cornelius, Lyndon A. M, Dai, Jun, Gullo-Brown, Johnni, Gupta, Ashok, Henley, Benjamin, Hunt, John T, Jeyaseelan, Robert, Kamath, Amrita, Kim, Kyoung, Lippy, Jonathan, Lombardo, Louis J, Manne, Veeraswamy, Oppenheimer, Simone, Sack, John S, Schmidt, Robert J, Shen, Guoxiang, Stefanski, Kevin, Tokarski, John S, Trainor, George L, Wautlet, Barri S, Wei, Donna, Williams, David K, Zhang, Yingru, Zhang, Yueping, Fargnoli, Joseph, Borzilleri, Robert M
Published in Journal of medicinal chemistry (12.03.2009)
Published in Journal of medicinal chemistry (12.03.2009)
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Gene-delivered butyrylcholinesterase is prophylactic against the toxicity of chemical warfare nerve agents and organophosphorus compounds
Parikh, Kalpana, Duysen, Ellen G, Snow, Benjamin, Jensen, Neil S, Manne, Veeraswamy, Lockridge, Oksana, Chilukuri, Nageswararao
Published in The Journal of pharmacology and experimental therapeutics (01.04.2011)
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Senescence Marker Protein 30
Arun, Peethambaran, Aleti, Vineela, Parikh, Kalpana, Manne, Veeraswamy, Chilukuri, Nageswararao
Published in PloS one (09.02.2011)
Published in PloS one (09.02.2011)
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Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors
Lackner, Mark R., Kindt, Rachel M., Carroll, Pamela M., Brown, Katherine, Cancilla, Michael R., Chen, Changyou, de Silva, Heshani, Franke, Yvonne, Guan, Bo, Heuer, Tim, Hung, Tak, Keegan, Kevin, Lee, Jae Moon, Manne, Veeraswamy, O’Brien, Carol, Parry, Dianne, Perez-Villar, Juan J., Reddy, Rajashekar K., Xiao, Hong, Zhan, Hangjun, Cockett, Mark, Plowman, Greg, Fitzgerald, Kevin, Costa, Michael, Ross-Macdonald, Petra
Published in Cancer cell (01.04.2005)
Published in Cancer cell (01.04.2005)
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Reversal of transformed phenotype by monoclonal antibodies against Ha- ras p21 proteins
Kung, Hsiang-Fu, Smith, Mark R., Bekesi, Eva, Manne, Veeraswamy, Stacey, Dennis W.
Published in Experimental cell research (01.02.1986)
Published in Experimental cell research (01.02.1986)
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Identification of pyrrolo[2,1- f][1,2,4]triazine-based inhibitors of Met kinase
Schroeder, Gretchen M., Chen, Xiao-Tao, Williams, David K., Nirschl, David S., Cai, Zhen-Wei, Wei, Donna, Tokarski, John S., An, Yongmi, Sack, John, Chen, Zhong, Huynh, Tram, Vaccaro, Wayne, Poss, Michael, Wautlet, Barri, Gullo-Brown, Johnni, Kellar, Kristen, Manne, Veeraswamy, Hunt, John T., Wong, Tai W., Lombardo, Louis J., Fargnoli, Joseph, Borzilleri, Robert M.
Published in Bioorganic & medicinal chemistry (15.03.2008)
Published in Bioorganic & medicinal chemistry (15.03.2008)
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Preclinical antitumor activity of BMS-214662, a highly apoptotic and novel farnesyltransferase inhibitor
ROSE, William C, LEE, Francis Y. F, FAIRCHILD, Craig R, LYNCH, Mark, MONTICELLO, Thomas, KRAMER, Robert A, MANNER, Veeraswamy
Published in Cancer research (Chicago, Ill.) (15.10.2001)
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Published in Cancer research (Chicago, Ill.) (15.10.2001)
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Design, synthesis and structure–activity relationships of novel biarylamine-based Met kinase inhibitors
Williams, David K., Chen, Xiao-Tao, Tarby, Christine, Kaltenbach, Robert, Cai, Zhen-Wei, Tokarski, John S., An, Yongmi, Sack, John S., Wautlet, Barri, Gullo-Brown, Johnni, Henley, Benjamin J., Jeyaseelan, Robert, Kellar, Kristen, Manne, Veeraswamy, Trainor, George L., Lombardo, Louis J., Fargnoli, Joseph, Borzilleri, Robert M.
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
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Discovery of (R)-7-Cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity
Hunt, John T, Ding, Charles Z, Batorsky, Roberta, Bednarz, Mark, Bhide, Rajeev, Cho, Young, Chong, Saeho, Chao, Sam, Gullo-Brown, Johnni, Guo, Peng, Kim, Soong Hoon, Lee, Francis Y. F, Leftheris, Katerina, Miller, Arthur, Mitt, Toomas, Patel, Manorama, Penhallow, Becky A, Ricca, Carol, Rose, William C, Schmidt, Robert, Slusarchyk, William A, Vite, Gregory, Manne, Veeraswamy
Published in Journal of medicinal chemistry (05.10.2000)
Published in Journal of medicinal chemistry (05.10.2000)
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